This paper aims to overview the dynamical character of science and scientific knowledge within the changing biotechnological era, as well as the emergent discourse of geneticization and its relevance to genetic counseling and the human body. Its main purpose is to carefully explore and comprehensively critique the contemporary theoretical literature on these distinct but interdependent issues from an interdisciplinary standpoint. The paper encourages further critical contributions to thinking about what it means to be human, as well as about how to (...) cope with current genetic and bodily knowledge and practices.key words: science, genetic knowledge, human body, nature, ethics. (shrink)

There is a gap in the clinical bioethics literature concerning the approach to assessment of medical decision-making capacity of adolescents or young adults who demonstrate diminished maturity due to longstanding reliance on caregiver support, despite having reached the age of majority. This paper attempts to address this question via the examination of a particular case involving assessment of the decision-making capacity of a young adult pregnant patient who also had a physically disabling neurological condition. Drawing on concepts from adolescent bioethics (...) and feminist critiques of bioethical theory, we argue that limited life experience, secondary to a disabling neurological condition, can result in a lack of adult-like capacity even in a patient who is legally an adult. In such cases, it may be that autonomy, to the extent that it is to be relevant and meaningful, must be viewed through a relational lens. Furthermore, clinicians may avoid unjustifiably paternalistic practices by working with the patient help her gain a better appreciation of the consequences of her decision, thereby calling forward her capacity rather than resorting to being directive in counseling. We conclude that lessons from this case can be used to approach ethically complex instances of medical decision-making in adult patients with normal cognition but diminished experiential maturity. (shrink)

We examined how social cues and representational ones jointly shape people's spatial memory representations and their subsequent descriptions. In 24 pairs, Directors studied an array with a symmetrical structure while either knowing their Matcher's subsequent viewpoint or not. During the subsequent description of the array, the array's intrinsic structure was aligned with the Director, the Matcher, or neither partner. According to memory tests preceding descriptions, Directors who had studied the array while aligned with its structure were more likely to use (...) its orientation as an organizing direction. Directors who had studied the array while misaligned with its structure used its orientation more frequently as an organizing orientation when knowing that the Matcher would be aligned with it, but used their own viewpoint more frequently as an organizing direction when not knowing the Matcher's viewpoint. Directors also adapted their descriptions strategically, using more egocentric expressions when aligned with the intrinsic structure and more partner-centered expressions when their Matchers were the ones aligned with the structure, even when this information wasn't available in advance. These findings suggest that speakers are guided by converging social and representational cues to adapt flexibly the organization of their memories and the perspectives of their descriptions. (shrink)

In this article we present a possible way to make usual quantum mechanics fully compatible with physical realism, defined as the statement that the goal of physics is to study entities of the natural world, existing independently from any particular observer’s perception, and obeying universal and intelligible rules. Rather than elaborating on the quantum formalism itself, we propose a new quantum ontology, where physical properties are attributed jointly to the system, and to the context in which it is embedded. In (...) combination with a quantization principle, this non-classical definition of physical reality sheds new light on counter-intuitive features of quantum mechanics such as the origin of probabilities, non-locality, and the quantum-classical boundary. (shrink)

Written in the 1960s, TRUTH AND METHOD is Gadamer's magnum opus.

In previous articles we presented a simple set of axioms named “Contexts, Systems and Modalities”, where the structure of quantum mechanics appears as a result of the interplay between the quantized number of modalities accessible to a quantum system, and the continuum of contexts that are required to define these modalities. In the present article we discuss further how to obtain Born’s rule within this framework. Our approach is compared with other former and recent derivations, and its strong links with (...) Gleason’s theorem are particularly emphasized. (shrink)

Systemic risks are risks produced through interconnected non-wrongful actions of individuals, in the sense that an individual's action is a negligible cause of the risk. Due to scale effects of interaction, their consequences can be serious but they are also difficult to predict and assess via a risk assessment. Since we can have good reason to engage in the interconnected activities giving rise to systemic risk, we incur a concurrent collective responsibility to ensure that the risks are fairly distributed and (...) well regulated. James argues that fairness in this context requires taking reasonably available precautions ensuring for each risk-bearer a favourable ratio of expected benefits over expected losses. In sections 2 and 3 we argue that such a conception of fairness applies but only on the condition that the systemic risks created are irreversible risks and that the general background conditions of justice are imperfectly fair. When risks are reversible, compensatory justice can correct for unfairness in risk imposition. Where risks are irreversible, compensatory justice necessarily fails, giving rise to a collective responsibility to regulate fairly ex ante. Additionally, where background conditions of justice are fully fair and the systemic risk is well understood, risk bearers can be said to have consented to the systemic risk. If they are not fair, we argue that the primary political obligation should lie in fixing the fairness of the backgrounds of justice. A related reason for addressing the general background conditions of fairness is that James’ account of fairness in systemic risk imposition encounters a baseline problem. If expected risks and benefits are calculated again an unfair historic background condition, systemic risk imposition would not be fully fair. Section 4 shows why differences in evidentiary uncertainty as to probability and levels of harm and effective responses require a normatively appropriate response in the form of additional precautions. We show that the evidentiary standards set for risk-based cost-benefit analysis have a connection with deontology because they express a postulate of equal treatment in formal terms. Systemic risks can have different possible degrees of epistemological certainty due to factors of social and natural origin, such as more available research funding or higher degrees of complexity for some systemic risks but not others. These differences have to be mitigated by taking even greater precautions in difficult-to-research systemic risks. (shrink)

George Berkeley (1685-1753) is the superstar of Irish Philosophy. He entered Trinity College, Dublin, in 1700 and became a fellow in 1707. In 1724 he resigned his Fellowship to become Dean of Derry, and in 1734 he was made Bishop of Cloyne. He settled in Oxford in 1752 and died the following year. The work of George Berkeley is marked by its diversity and range. His writings take in such topics as mathematics, psychology, politics, health, economics, deism and (...) education, as well as that with which he is most associated - philosophy. Whatever topic he dealt with, his grasp of the subject matter was always impressive and his criticisms of his contemporaries often acute. Among the most noteable of the British Empiricists, he took his starting point from Locke's new 'way of ideas', but he rejected abstract ideas and the possibility of real existence outside perception. It is for this doctrine that he is most known - that there is no such thing as matter, and that things are collections of ideas which can exist only in our minds and only for so long as they are perceived. This philosophy, summed up in his phrase 'to be is to be perceived', he termed 'immaterialism'. A.C. Fraser's collection includes a series of what were previously unpublished notes by Berkeley on all the main topics of his philosophy. This, the 1901 edition, was the first complete edition of his works. (shrink)

This paper aims to show that fairness in trade calls for relaxing existing WTO rules to include a greater liberalisation of labour migration. After having addressed several objections to global egalitarianism, it will argue, first, that the world’s rich and the world’s poor participate in a same multilateral trading system whose point is primarily to reduce trade barriers, and hence to establish global economic competitions, in order to raise their standards of living; second, that these competitions are subject to requirements (...) of formal and substantive fairness; and, third, that the substantive fairness of the competitions that are taking place in the field of trade in goods is likely to require a greater liberalisation of labour migration, especially low-skilled labour from developing countries. (shrink)

A brilliant and comprehensive history of the creation of the modern Western mind. Soul Machine takes us back to the origins of modernity, a time when a crisis in religious authority and the scientific revolution led to searching questions about the nature of human inner life. This is the story of how a new concept—the mind—emerged as a potential solution, one that was part soul and part machine, but fully neither. In this groundbreaking work, award-winning historian George Makari shows (...) how writers, philosophers, physicians, and anatomists worked to construct notions of the mind as not an ethereal thing, but a natural one. From the ascent of Oliver Cromwell to the fall of Napoleon, seminal thinkers like Hobbes, Locke, Diderot, and Kant worked alongside often-forgotten brain specialists, physiologists, and alienists in the hopes of mapping the inner world. Conducted in a cauldron of political turmoil, these frequently shocking, always embattled efforts would give rise to psychiatry, mind sciences such as phrenology, and radically new visions of the self. Further, they would be crucial to the establishment of secular ethics and political liberalism. Boldly original, wide-ranging, and brilliantly synthetic, Soul Machine gives us a masterful, new account of the making of the modern Western mind. (shrink)

A coletânea de artigos de Herbert Marcuse comemora em 2007 o lançamento de mais um volume: Art and Liberation. Originada de uma série de visitas empreendidas, a partir de 1989, por Douglas Kellner aos Arquivos Marcuse em Frankfurt, esta coletânea de artigos prevê o lançamento de seis volumes, cada um dos quais dedicado ao tratamento de um tema específico. Único impresso no Brasil, o primeiro engloba alguns textos escritos em colaboração com o governo norte-americano, e discute a relação entre a (...) tecnologia, a guerra e o fascismo (MARCUSE, 1999). (shrink)

Throughout The Blessed and Boundless God, he proves his doctrine by demonstrating God's incomparableness in His being, attributes, works, and words. Swinnock is a pastor-theologian who views theology as the means by which we grow in acquaintance with God and, consequently, in godliness.

Gustave de Molinari (1819–1912) is one of the most important representatives of the French liberal school in the 19th century. Although a Belgian by birth, he is, without contest, a member of the French tradition in the same way as Jean-Baptiste Say or Frédéric Bastiat. Yet, his work is little-known, or only limited to the knowledge of his most controversial theories, which are set out in his most famous publications, “De la Production de la Sécurité.

Résumé Cet article explore le processus de déshumanisation et ses effets sur les individus et plus particulièrement sur leur corps. Pour approcher l’univers de la déshumanisation, les auteurs se sont plongées dans l’irreprésentable des violences génocidaires survenues dans la région des Grands Lacs au Burundi. Deux grandes interrogations constituent le fil rouge de la réflexion : le corps et le paradoxal. Le cas de Nemesa, jeune ex-rebelle burundaise, a permis de penser la souffrance paradoxale liée aux violences extrêmes et inhumaines.

Résumé Cet article explore le processus de déshumanisation et ses effets sur les individus et plus particulièrement sur leur corps. Pour approcher l’univers de la déshumanisation, les auteurs se sont plongées dans l’irreprésentable des violences génocidaires survenues dans la région des Grands Lacs au Burundi. Deux grandes interrogations constituent le fil rouge de la réflexion : le corps et le paradoxal. Le cas de Nemesa, jeune ex-rebelle burundaise, a permis de penser la souffrance paradoxale liée aux violences extrêmes et inhumaines.

Through theoretical discussion, literature review, and a computational model, this paper poses a challenge to the notion that perspective-taking involves a fixed architecture in which particular processes have priority. For example, considerable work has shown that egocentric perspectives can arise more quickly, with other perspectives (such as of task partners) emerging only secondarily. This theoretical dichotomy is challenged here, and we propose a general view of perspective-taking as an emergent phenomenon governed by the interplay among several cognitive mechanisms. We first (...) describe the pervasive relevance of perspective-taking to cognitive science. A dynamical systems model is then introduced which explicitly formulates the timescale interaction proposed. Implications are discussed, with ideas for future empirical research. (shrink)

Although there is a growing recognition that older adults and those with extensive comorbid conditions undergo cancer screening too frequently, there is little information about patients’ perceptions regarding cessation of cancer screening. Information on older adults’ views of screening cessation would be helpful both for clinicians and for those designing interventions to reduce overscreening.

Olgária Chain Féres Matos é professora titular aposentada pelo Departamento de Filosofia da Universidade de São Paulo e professora titular no Departamento de Filosofia da Universidade Federal de São Paulo. Sua trajetória tem início em fins dos anos 1960, quando ingressa como estudante na Faculdade de Filosofia, Ciências e Letras da Universidade de São Paulo, então situada à rua Maria Antonia. Rousseau, Marcuse, Adorno, Derrida e principalmente Walter Benjamin são algumas de suas referências filosóficas mais importantes, a partir das quais (...) a filósofa compõe uma constelação de ideias animadas pelo afeto e pelo erótico. Tendo a utopia como bússola, o desvio como método e a astúcia como guia, seu esforço constantemente renovado é o de iluminar os clássicos com a potência do efêmero e o brilho questionador do extemporâneo. (shrink)

Aujourd’hui, la question du consentement se règle par une dichotomie universellement admise : oui c’est oui et non c’est non. Mais que faire des « peut-être », des silences, des hésitations, ou encore des relations sexuelles acceptées mais non désirées? En déplaçant la focale analytique sur les sexualités quotidiennes des individu-e-s, le consentement apparaît finalement comme un spectre constitué de « zones grises », impossibles à expliquer via le cadre juridique et social du « vrai viol » ou du consentement (...) « libre et éclairé ». Pourtant, cette vision binaire hégémonique est la seule lecture reconnue pour juger de la légalité des pratiques sexuelles en France. Cet article pointe ainsi le décalage d’un système juridique garant d’une égalité théorique qui s’exerce au sein d’une société hétéronormative, et questionne l’efficacité des dispositifs institutionnels actuels pour comprendre et réguler le consentement sexuel. (shrink)

Jane Campion’s work regularly revolves around women’s often complex relationship with socio-cultural discourses and their articulation in language, whether in familial and institutional structures or in cultural and creative practice. In this sense, Campion’s filmmaking continues a feminist tradition of exploration regarding female subjectivity, identity and desire as it is represented in language (cinematic or otherwise). In the Cut (2003), adapted from Susanna Moore’s novel of the same name, again places language and the (dis)articulation of the female voice at its (...) heart: the renewal of which is positioned within the film as crucial to women’s survival. In taking its cue from Hélène Cixous’s ‘The Laugh of the Medusa’ (1976) and later writings such as ‘Castration or Decapitation?' (1981) and ‘Coming to Writing' (1991), this article frames its discussion of Campion’s interrogation of ‘Woman’s’ attempts at the articulation of the self as an exemplar (in both theme and form) of Cixousian strategies. The article will argue that techniques such as a cinematic écriture feminine, and the appropriation and adaptation of the language of Hollywood genre film, form part of Campion’s feminist inquiry into the discourses and legacies of a phallogocentric patriarchal culture which traditionally delimit Woman as a ‘speaking’ subject. In this way, In the Cut exposes the tensions between what Cixous calls the ‘Absolute Woman’ of culture (the aphonic hysteric) and attempts towards agency, thus challenging phallogocentric representations of women. In using these strategies, Campion’s adaptation creates a polyphonic artefact which not only revises Moore’s novel but also re-visits (in order to reclaim) female articulation; re-writing phallogocentric claims to agency and subjectivity, imagining women's ‘survival’ through language. In this sense, then, adaptation itself can be thought of as a feminist act of subversion. (shrink)

Resumo: Para ampliar a compreensão das problemáticas ambientais atuais, este texto reúne as análises interpretativas de dois documentos, os quais, por possuírem perspectivas distintas, contribuem significativamente com o estudo da teoria fleckiana. São dois coletivos de pensamento desenvolvendo práticas científicas com intencionalidades advindas das opções teóricas e políticas, configurando um processo dinâmico de produção de conhecimento. A essência de cada um desses coletivos de pensamento consiste na ampliação e na disseminação da ideia transpessoal, por ela não pertencer, de forma exclusiva, (...) a nenhum dos componentes do coletivo. Propiciar a troca constante de concepções interna e externamente impulsiona o conhecimento científico, cuja evolução depende do processo coletivo em que o pensamento se desenvolve por vínculos e interferências engendradas pelo condicionamento social.: With the intention of broadening the understanding of current environmental issues, this article contains interpretive analysis of two documents which, because of their different perspectives, contribute significantly to the study of Fleckian theory. They are two collective thought manifestoes which develop scientific practices, their goals arising from theoretical and political options that configure a dynamic process of knowledge production. The essence of each of these collective thoughts consists in the expansion and spread of transpersonal ideas that do not belong exclusively to any of the components of the collective. Propitiating the constant exchange of internal and external views drives scientific knowledge, whose evolution depends on a collective process in which thought is developed by bonds and interferences engendered by social conditioning. (shrink)

Salvo contadas excepciones, el itinerario de Antonio Gramsci en la Argentina es generalmente asociado a los gramscianos argentinos reunidos en la revista Pasado y presente, encabezada por José Aricó, sin atender a su historia previa. Sin embargo, se olvida u omite que la introducción del pensamiento de Gramsci en este país fue realizada por Héctor P. Agosti, quien ejerció una notable influencia en muchos de aquellos jóvenes que luego confluirían en el grupo en torno a Aricó. El objetivo de este (...) trabajo es, más allá de las observaciones que se hacen sobre los detractores de Agosti, contribuir a la difusión, y presentación en algunos casos, del pensamiento de uno de los intelectuales más notables que ha dado el Partido Comunista Argentino . Se pretende profundizar en algunos de los vínculos entre las elaboraciones teóricas de Agosti y las de Gramsci que no han sido suficientemente atendidos, así como incidir en el papel que Agosti tuvo en la inserción del pensador italiano en el debate comunista argentino. (shrink)

Although tissue plasminogen activator (tPA) is the only medication approved by the United States Food and Drug Administration (FDA) for acute ischemic stroke, there is no consensus about the need for informed consent for its use. As a result, hospitals throughout the U.S. have varying requirements regarding obtaining informed consent from patients for the use of tPA, ranging from no requirement for informed consent to a requirement for verbal or written informed consent. We conducted a study to (1) determine current (...) beliefs about obtaining patients’ informed consent for tPA among a large group of stroke clinicians and (2) identify the ethical, clinical, and organizational factors that influence tPA consent practices. Semi-structured interviews were conducted by trained and experienced investigators and research staff to identify key barriers to implementing acute stroke services. Part of the interview explored current beliefs and practices around informed consent for tPA.This was a multicenter study that included 38 Veterans Health Administration (VHA) hospital locations. Participants were 68 stroke team clinicians, serving primarily on the neurology (35 percent) or emergency medicine (41 percent) service. We conducted thematic analysis based on principles of grounded theory to identify codes about consent for tPA. We used interpretive convergence to ensure consistency among the individual investigators’ codes and to ensure that all of the investigators agreed on coding and themes.We found that 38 percent of the stroke clinicians did not believe any form of consent was necessary for tPA, 47 percent thought that some form of consent was necessary, and 15 percent were unsure. Clinicians who believed tPA required informed consent were divided on whether consent should be written (40 percent) or verbal (60 percent). We identified three factors describing clinicians’ attitudes about consent: (1) legal and policy factors, (2) ethical factors, and (3) medical factors.The lack of consensus regarding consent for tPA creates the potential for delays in treatment, uneasiness among clinicians, and legal liability. The identified factors provide a potential framework to guide discussions about developing a standard of care for acquiring the informed consent of patients for the administration of tPA. (shrink)

George Herbert Mead (1863-1931) had a powerful influence on the development of American pragmatism in the twentieth century. He also had a strong impact on the social sciences. This classic book represents Mead's philosophy of experience, so central to his outlook. The present as unique experience is the focus of this deep analysis of the basic structure of temporality and consciousness. Mead emphasizes the novel character of both the present and the past. Though science is predicated on the assumption (...) that the present is predictable based on a thorough knowledge of the past, the experience of the present, says Mead, is an utterly unique moment comparable to no other, and when it is past the novel character of that unique experience is irrevocable. The emergence of novelty within the perceived rational order of reality is the crux of the problem that Mead explores. The present, in his words, is "the emergent event . . . something which is more than the processes that have led up to it and which by its change, continuance, or disappearance, adds to later passages a content they would not otherwise have possessed." The present as "the seat of reality" heavily conditions our retrospective view of the past as much as it helps to shape the future. The novelty of every present experience causes us to reconstruct our preceding experiences to make sense of the past, which is naturally assumed to be the main cause of what we presently experience. Our perspective on reality is thus relative to the conditioning of each new event and it changes continuously as the effects of the present shift our view of the past and future. This emphasis on the integrative, holistic nature of reality, in which everything past, present, and future is a condition of everything else, makes Mead's philosophy highly relevant to today's scientific picture of a quantum universe, where chance and probability play a role in the emergence of reality. Also of great interest is the way in which he extends his basic analysis of temporal-spatial reality to the emergence of mind and consciousness as a natural development of the evolutionary process. This stimulating and provocative work attests to John Dewey's praise of Mead as "the most original mind in philosophy in America" of his generation. (shrink)

touch 27 Thirrdly, the straining of the eye 28 The occasions which suggest distance have in their own nature no relation to it 29 A difficult case proposed by Dr. Barrow as repugnant to all the known theories 30 This case contradicts a ...

The Oxford Philosophical Texts series consists of authoritative teaching editions of canonical texts in the history of philosophy from the ancient world down to modern times. Each volume provides a clear, well laid out text together with a comprehensive introduction by a leading specialist,giving the student detailed critical guidance on the intellectual context of the work and the structure and philosophical importance of the main arguments. Endnotes are supplied which provide further commentary on the arguments and explain unfamiliar references and (...) terminology, and a fullbibliography and index are also included.The series aims to build up a definitive corpus of key texts in the Western philosophical tradition, which will form a reliable and enduring resource for students and teachers alike.In his Principles of Human Knowledge Berkeley makes the striking claim that physical things consist of nothing but ideas, and so do not exist outside the mind. This establishes Berkeley as the founder of the idealist tradition in philosophy. Berkeley argues vigorously that once we correct ourunderstanding of the physical, we can find a new proof of the existence of God, refute sceptical attacks on human knowledge, and resolve many difficulties and paradoxes raised by the advance of science.The text printed in this volume is the 1734 edition of the Principles which is generally agreed to represent Berkeley's mature thought. Also included are the four important letters between George Berkeley and Samuel Johnson, written in 1729-30. The text is supplemented by a comprehensiveintroduction which looks at the structure and main arguments of the text, as well as discussing Berkeley's life, influences, and general philosophy. In addition the volume includes an analysis of the text, a glossary, detailed notes, and a full bibliography with guidance on further reading.This new edition of Berkeley's most famous work, published alongside his other masterpiece, the Three Dialogues (also edited by Jonathan Dancy) provides the student with a thorough introduction to the central ideas of one of the world's greatest philosophers. (shrink)

This book, written by one of the most distinguished of contemporary philosophers of mathematics, is a fully rewritten and updated successor to the author's earlier The Unprovability of Consistency. Its subject is the relation between provability and modal logic, a branch of logic invented by Aristotle but much disparaged by philosophers and virtually ignored by mathematicians. Here it receives its first scientific application since its invention. Modal logic is concerned with the notions of necessity and possibility. What George Boolos (...) does is to show how the concepts, techniques, and methods of modal logic shed brilliant light on the most important logical discovery of the twentieth century: the incompleteness theorems of Kurt Godel and the 'self-referential' sentences constructed in their proof. The book explores the effects of reinterpreting the notions of necessity and possibility to mean provability and consistency. (shrink)

First published in 1713, this work was designed as a vivid and persuasive presentation of the remarkable picture of reality that Berkeley had first presented two years earlier in his Principles of Human Knowledge. His central claim there, as here, was that physical things consist of nothing but ideas in minds--that the world is not material but mental. Berkeley uses this thesis as the ground for a new argument for the existence of God, and the dialogue form enables him to (...) raise and respond to many of the natural objections to his position. The text printed in this volume is that of the 1734 edition of the Dialogues. (shrink)