We hypothesize that heritable epigenetic changes can affect rates of fitness increase as well as patterns of genotypic and phenotypic change during adaptation. In particular, we suggest that when natural selection acts on pure epigenetic variation in addition to genetic variation, populations adapt faster, and adaptive phenotypes can arise before any genetic changes. This may make it difficult to reconcile the timing of adaptive events detected using conventional population genetics tools based on DNA sequence data with environmental drivers of adaptation, (...) such as changes in climate. Epigenetic modifications are frequently associated with somatic cell differentiation, but recently epigenetic changes have been found that can be transmitted over many generations. Here, we show how the interplay of these heritable epigenetic changes with genetic changes can affect adaptive evolution, and how epigenetic changes affect the signature of selection in the genetic record. (shrink)

This research aims to examine access to medical treatment during the COVID-19 pandemic for people living with disabilities. During the COVID-19 pandemic, the practical and ethical problems of allocating limited medical resources such as intensive care unit beds and ventilators became critical. Although different countries have proposed different guidelines to manage this emergency, these proposed criteria do not sufficiently consider people living with disabilities. People living with disabilities are therefore at a higher risk of exclusion from medical treatments as physicians (...) tend to assume they have poor quality of life, whereas access to medical treatment should be based on several parameters, including clinical data and prognosis. However, the COVID-19 pandemic shifts the medical paradigm from person-centred medicine to community-centred medicine, challenging the main ethical theories. We reviewed the main guidelines and recommendations for resources allocation and examined their position toward persons with disabilities. Based on our findings, we propose criteria for not discriminating against people with disabilities in allocating resources. The shift from person-centred to community-centred medicine offers opportunities but also risks sacrificing the most vulnerable people. The principle of reasonable accommodation must always be considered to guarantee the rights of persons with disabilities. (shrink)

This book identifies the criteria for successful constitutions in both theory and practice using the research and methodology of Vincent Ostrom.

BackgroundInformation and communication technology solutions have the potential to support active and healthy aging and improve monitoring and treatment outcomes. To make such solutions acceptable, all stakeholders must be involved in the requirements elicitation process. Due to the COVID-19 situation, alternative approaches to commonly used face-to-face methods must often be used. One aim of the current article is to share a unique experience from the Pharaon project where due to the COVID-19 outbreak alternative elicitation methods were used. In addition, an (...) overview of common functional, quality, and emotional goals identified by six pilot sites is presented to complement the knowledge about the needs of older adults.MethodsOriginally planned face-to-face co-creation seminars were impossible to carry out, and all pilot sites chose alternative requirements elicitation methods that were most suitable in their situation. The elicited requirements were presented in the form of goal models. In one summary goal model, we provide an overview of common functional, quality, and emotional goals.ResultsDifferent elicitation methods were combined based on the digital literacy of the target group and their access to digital tools. Methods applied without digital technologies were phone interviews, reviews of literature and previous projects, while by means of digital technologies online interviews, online questionnaires, and virtual co-creation seminars were conducted. The combination of the methods allowed to involve all planned stakeholders. Virtual and semi-virtual co-creation seminars created collaborative environment comparable to face-to-face situations, while online participation helped to save the time of the participants. The most prevalent functional goals elicited were “Monitor health,” “Receive advice,” “Receive information.” “Easy to use/comfortable,” “personalized/tailored,” “automatic/smart” were identified as most prevalent quality goals. Most frequently occurring emotional goals were “involved,” “empowered,” and “informed.”ConclusionThere are alternative methods to face-to-face co-creation seminars, which effectively involve older adults and other stakeholders in the requirements elicitation process. Despite the used elicitation method, the requirements can be easily transformed into goal models to present the results in a uniform way. The common requirements across different pilots provided a strong foundation for representing detailed requirements and input for further software development processes. (shrink)

Étienne Souriau a développé une philosophie originale de l’Instauration enracinée dans une nouvelle anthropologie de la création : l’homme est conçu comme l’ animal instaurateur. Il a développé systématiquement cette intuition fondatrice en explorant ses enjeux à l’intérieur de trois domaines principaux : l’instauration artistique (l’art étant le genre le plus pur de l’instauration, il constitue le modèle pour les autres), l’instauration philosophique, et enfin ce qu’il a appelé « l’instauration de soi ». Ce dernier domaine instauratif a été thématisé (...) dans un cours public que Souriau a donné à Lyon en 1929-1930, qui s’intitulait justement L’esthétique et l’art de vivre. La vie constitue donc une matière à partir de laquelle on peut donner une forme (forme-de-vie) et qui peut devenir ainsi, en elle-même, œuvre. Mais – on pourrait se demander – de quelle forme s’agit-il? Souriau répond que la vie peut être matière, tour à tour prenant des formes pythagoriques, dynamiques, skeuologiques et psycho-esthétiques. Il faudrait aussi considérer la notion d’ œuvre. L’œuvre d’art, précise Souriau, doit être considérée, en elle-même à l’instar d’une personne – c’est-à-dire comme un être plurimodal, qui rassemble en soi et synthétise plusieurs niveaux existentiels à la fois. Selon l’ontologie développée dans Les Différents Modes d’existence enfin, le plus haut but de l’existence doit être celui d’un devenir sur-existentiel, visant à se dépasser en transcendance, la vie devenant ainsi vie sublime. On pourrait donc soutenir que, selon Souriau, la vie peut devenir une œuvre d’art, et l’œuvre d’art est une forme-de-vie. (shrink)

BERNARD VOUILLOUX, L’oeuvre en souffrance. Belin 2004 BERNARD VOUILLOUX, Tableaux d’auteurs. P.U.V. 2004.

In the ontology of the artwork and its regimes of existence, Gérard Genette gives but little room to the theory and practice of restoration. However, restoration is seen in relation to the identity of the work itself and to its material and pragmatic temporality and anachronism. In the wake of Nelson Goodman, it is also understood as a form of actuation and implementaion of the aesthetic experience. Starting from these premises, the present essay intends to examine the relationship between Genette’s (...) and Daniel Arasse’s reflections on restoration and the history of art, highlighting their similarities and differences with Cesare Brandi’s theory of restoration and, therefore, pointing out their as yet undischarged debts to Sartre’s phenomenology of image. (shrink)

Étienne Souriau (1892-1979) demeure un philosophe et esthécien français du xx e siècle encore largement méconnu. Cette première biographie coécrite par Filippo Domenicali et Fabien Le Tinnier – regroupant leurs recherches respectives sur l’œuvre d’Étienne Souriau, pour l’un sur ses années lyonnaises, l’autre sur ses années parisiennes –, cherche à restaurer la place qu’occupait l’œuvre du philosophe au sein de l’histoire de la philosophie française contemporaine. Fondée sur l’étude de nombreuses archives pour la première fois mises au jour, cette biographie (...) retrace le cursus honorem du professeur Souriau durant plus soixante ans. En resituant ainsi la trajectoire intellectuelle de Souriau, l’évolution de sa carrière, la toile de ses amitiés philosophes ainsi que ses réseaux collégiaux parmi les lieux qu’il a fréquenté, cette biographie vise encore à éclairer son travail à la lumière des livres, idées et événements qui ont chacun participé à façonner son abondante œuvre philosophique que depuis quelques années de nombreux chercheurs et universitaires français, belges et italiens redécouvrent. Depuis ses années parisiennes de formation passées à l’École Normale Supérieure jusqu’au faste de ces années passée à l’université de Paris occupant la chaire d’esthétique à partir de juillet 1946, Souriau fait rayonner la philosophie française par-delà les frontières françaises comme en témoignent ses nombreuses publications étrangères et déplacements professionnels. Figure majeure de la philosophie universitaire, Souriau et son œuvre parcourent ainsi le monde philosophique du milieu du xx e siècle. (shrink)

Non c’è alcun dubbio, Leibniz si sbagliava: non viviamo nel migliore dei mondi possibili. In passato, l’arte perlomeno forniva all’uomo consolazione sotto forma di opere che, con la loro bellezza, profondità e inventività, suggerivano vie d’uscita dalla realtà o dischiudevano nuovi orizzonti. Ma ai nostri giorni, non ci è più possibile trovare conforto nell’arte, specie se ci immergiamo nel mondo delle arti visive, dove a dominare incontrastate il mercato, a ricevere le più entusiastiche recensioni critiche e a stimolare l’interesse dei (...) filosofi sono opere davvero povere d’immaginazione formale e, conseguentemente, di contenuto incarnato. Basti pensare ai teschi tempestati di diamanti di Damien Hirst, ai bambini-manichini appesi da Cattelan a un albero di Porta Ticinese a Milano, ai cani di palloncini di Jeffrey Koons, o al Terzo Paradiso di Pistoletto. Cosa possono fare gli studiosi di estetica per invertire la rotta, per rendere il nostro mondo, se non il migliore dei mondi possibili, per lo meno artisticamente più allettante di quello odierno? La risposta la si potrà trovare nella messa a punto di una definizione estetica dell’arte e di un perfezionamento dei suoi criteri di classificazione, che sono anche norme di valutazione. (shrink)

Answering some of the main questions from [L. Motto Ros, The descriptive set-theoretical complexity of the embeddability relation on models of large size, Ann. Pure Appl. Logic164(12) (2013) 1454–1492], we show that whenever κ is a cardinal satisfying κ<κ=κ>ω, then the embeddability relation between κ-sized structures is strongly invariantly universal, and hence complete for (κ-)analytic quasi-orders. We also prove that in the above result we can further restrict our attention to various natural classes of structures, including (generalized) trees, graphs, or (...) groups. This fully generalizes to the uncountable case the main results of [A. Louveau and C. Rosendal, Complete analytic equivalence relations, Trans. Amer. Math. Soc.357(12) (2005) 4839–4866; S.-D. Friedman and L. Motto Ros, Analytic equivalence relations and bi-embeddability, J. Symbolic Logic76(1) (2011) 243–266; J. Williams, Universal countable Borel quasi-orders, J. Symbolic Logic79(3) (2014) 928–954; F. Calderoni and L. Motto Ros, Universality of group embeddability, Proc. Amer. Math. Soc.146 (2018) 1765–1780]. (shrink)

In 1979, A. D. Woozley proposed an interpretation of Apology 29c–d which was intended to alleviate the well-known tension between the Apology and Crito on the citizen's obligation to obey the law. According to his interpretation, the court's hypothetical offer – to release Socrates on the condition that he will be put to death if he does not give up philosophy – is not an order, but a warning as to what would happen should he accept their acquittal and yet (...) continue to philosophize. Obviously, if this is the spirit of the words he puts into the court's mouth, Socrates would not be guilty of disobedience should he refuse the offer, or even if he should accept it and then disregard the warning. To support this interpretation, Woozley suggested a novel construal of the words in which Socrates makes his refusal – πεσομαι δ μγγον τ θε ἢ μν. (shrink)

In 1979, A. D. Woozley proposed an interpretation of Apology 29c–d which was intended to alleviate the well-known tension between the Apology and Crito on the citizen's obligation to obey the law. According to his interpretation, the court's hypothetical offer – to release Socrates on the condition that he will be put to death if he does not give up philosophy – is not an order, but a warning as to what would happen should he accept their acquittal and yet (...) continue to philosophize. Obviously, if this is the spirit of the words he puts into the court's mouth, Socrates would not be guilty of disobedience should he refuse the offer, or even if he should accept it and then disregard the warning. To support this interpretation, Woozley suggested a novel construal of the words in which Socrates makes his refusal – πεσομαι δ μγγον τ θε ἢ μν. (shrink)

L’estiu de 1947, tres joves amics, Yves Klein, Claude Pascal i Armand Fernandez, s’asseuen a la platja de Niça. Encara no són artistes, no fan res i perden el temps omplint-lo de projectes i paraules. Prenen el sol, miren el mar i el cel de la Mediterrània, fan declaracions entusiastes sobre el Gran Art del futur i comparteixen la natura, com uns nens que es divideixen un regne imaginari. Klein pren el blau del cel que abasta amb la mirada, com (...) el color absolut i ideal de la pintura. -/- Yves le Monochrome dirà diverses vegades que, aquell matí d’estiu, va fer un viatge fantàstic, com si fos un astronauta conquerint l’espai, i va signar, com si es tractés d’un llenç pintat de blau, l’altre costat d’aquest bell cel sense núvols: la més bella i la més gran de les seves obres. Aquest cel blau pintat de blau és una obra immaterial i impossible, no feta per les mans de l’artista, amb colors, pinzells i teles, sinó explicada amb les seves paraules, mites i llegendes. (shrink)

Cet article vise à éclairer le développement des visions méta-éthiques proposées par les deux fondateurs de l’approche des capabilités, Amartya Sen et Martha Nussbaum. Les deux auteurs fondent leurs différentes conceptions de la justice sur certaines versions de l’objectivisme et se confrontent aux questions d’argumentation rationnelle dans le cas de désaccords pratiques. La réponse est différente chez Sen et chez Nussbaum. Leurs justifications méta-éthique de la théorie et leurs visions du raisonnement pratique et de l’argumentation morale présentent des similitudes et (...) des différences. (shrink)

Inspired by the text entitled The Collapse of the Fact/Value Dichotomy and Other Essays (2004) of Hilary Putnam, the volume focuses on the theory and practice of knowledge, but one can legitimately extend it to other fields, most especially in aesthetics. Certain observable features in the fields of aesthetics, practice and artistic creation show that old evaluation criteria may now be obsolete. This is because upon further consideration, the definition of value remains opaque : should the artwork be judged according (...) to its moral value, its market value, or its formal value ? To side with or against the concept of value in art and aesthetics does not preclude a certain number of differences concerning the very nature of what is meant by value. If traditionally the ‘fact’ was the work, taken in all its tangibility, currently the materiality of the object no longer seems to play such a major role. Art is increasingly populated by so-called ‘immaterial’ or ‘ephemeral’ works and is therefore rarely, or badly, quantifiable according to old aesthetic and economic evaluation criteria. The progressively pragmatic contextualization of works within the social space puts forward a new definition of aesthetic value, no longer eternal and ideal, but rather anchored in the sensible and the politico-economic issues of a culturally specific situation. The current changes too support the idea that the question of ‘value’ and its confrontation with the concept of ‘fact’ is urgent. What role do artistic practices and aesthetic theories play ? A role of emancipation, of liberation, escape, or transformation ? Or on the contrary, could art become another means to subject individuals to the status quo ? As can easily be noticed, the question of maintaining or rejecting the dichotomy of facts and values is at the heart of the most pressing issues. (shrink)

The Seven Heavenly Palaces were created by Anselm Kiefer to inaugurate the HangarBicocca in Milan in 2004, and, after an intervention on the site in 2008, were transferred, preserved and repaired, finally relocated differently for a new and definitive exhibition, with some paintings, in 2015. Erected around prefabricated containers, these monumental ruins in reinforced concrete, are in fact assembled, reconstructed and restored ruins, nonarchitectural and metaphorical buildings with a mass of complementary materials considered an integral part of the work and (...) credited as produced by the artist in person. According to what preunderstandings and values the operation of conservation and operation has been established and carried out ? According to which idea of the ontological, perceptual and semantic identity of the work of art the aesthetic experience of this high problematic site-specific installation has been reconfigured ? (shrink)

Résumé Entre la construction d’une monstruosité étatique absolue, censée anéantir toute rébellion par la crainte et la menace (d’un côté) et la monstrification de la part du Pouvoir de tout «autre» rebelle, hérétique, contestataire (de l’autre), l’auteur indique la possibilité d’un troisième concept de la monstruosité. Une monstruosité qui échappe à cette alternative pour affirmer son altérité radicale, monstrueuse non pas par son apparence mais par sa revendication d’autonomie par rapport à toute norme transcendante et finaliste, dans l’immanence absolue de (...) sa condition actuelle et puissante. (shrink)

BackgroundFunctional changes after spinal cord injury are related to changes in cortical plasticity. These changes can be measured with electroencephalography and has potential to be used as a clinical biomarker.MethodIn this longitudinal study participants underwent a total of 30 sessions of robotic-assisted gait training over a course of 6 weeks. The duration of each session was 30 min. Resting state EEG was recorded before and after 30-session rehabilitation therapy. To measure gait, we used the Walking Index for Spinal Cord Injury (...) Scale, 10-Meter- Walking Test, Timed-Up-and-Go, and 6-Min-Walking Test. Balance was measured using Berg Balance Scale.ResultsFifteen participants with incomplete SCI who had AIS C or D injuries based on American Spinal Cord Injury Association Impairment Scale classification were included in this study. Mean age was 35.7 years and the mean time since injury was 17.08 months. All participants showed clinical improvement with the rehabilitation program. EEG data revealed that high beta EEG activity in the central area had a negative correlation with gait and balance measured at baseline, in a way that greater high beta EEG power was related to worse clinical function at baseline. Moreover, improvement in gait and balance had negative correlations with the change in alpha/theta ratio in the parietal area.ConclusionIn SCI, functional impairment and subsequent improvement following rehabilitation therapy with RAGT correlated with the change in cortical activity measured by EEG. Our results suggest that EEG alpha/theta ratio may be a potential surrogate marker of functional improvement during rehabilitation. Future studies are necessary to improve and validate these findings as a neurophysiological biomarker for SCI rehabilitation. (shrink)

This article surveys Filippo Tommaso Marinetti's social utopia from the inception of Futurism until its end during World War II, contextualizing it in relation to the various diffused anarchistic ideologies of European artists and intellectuals. From the second half of the nineteenth century onward radical politics and the artistic avant-garde were in close dialogue. Max Stirner's individual anarchy held a special appeal to modernist artists, including Gabriele D'Annunzio and Marinetti. Marinetti's aim of renovating Italy's cultural and political life initially led (...) him to glorify the destruction of old institutions. At the end of World War I he developed a more or less coherent utopian vision of a new society, based principally on the exaltation of individual freedom and the importance of art. During the Fascist regime, Marinetti abandoned politics and concentrated his efforts on making the Aerofuturism of the interwar years the official art of Fascism, which the Futurists saw as the fulfillment of their “anarchist” dream. (shrink)

This is the short version, in French translation by Anne Querrien, of the originally jointly authored paper: Müller, Vincent C., ‘Autonomous killer robots are probably good news’, in Ezio Di Nucci and Filippo Santoni de Sio, Drones and responsibility: Legal, philosophical and socio-technical perspectives on the use of remotely controlled weapons. - - - L’article qui suit présente un nouveau système d’armes fondé sur des robots qui risque d’être prochainement utilisé. À la différence des drones qui sont manoeuvrés à distance (...) mais comportent une part importante de discernement humain, il s’agit de machines programmées pour défendre, attaquer, ou tuer de manière autonome. Les auteurs, philosophes, préfèrent prévenir de leur prochaine diffusion et obtenir des Nations Unies leur régulation. Une campagne internationale propose plutôt leur interdiction. (shrink)

D. H. Mellor; VI*—Conscious Belief, Proceedings of the Aristotelian Society, Volume 78, Issue 1, 1 June 1978, Pages 87–102, https://doi.org/10.1093/aristotelian.

Everything we do relies on causation. We eat and drink because this causes us to stay alive. Courts tell us who causes crimes, criminology tell us what causes people to commit them. D.H. Mellor shows us that to understand the world and our lives we must understand causation. _The Facts of Causation_, now available in paperback, is essential reading for students and for anyone interested in reading one of the ground-breaking theories in metaphysics. We cannot understand the world and our (...) place in it without understanding causation. Yet a complete account of the nature and implications of causation does not exist. D.H Mellor's new book is that account. (shrink)

D. H. Mellor; VI*—Conscious Belief, Proceedings of the Aristotelian Society, Volume 78, Issue 1, 1 June 1978, Pages 87–102, https://doi.org/10.1093/aristotelian.

Everything we do relies on causation. We eat and drink because this causes us to stay alive. Courts tell us who causes crimes, criminology tell us what causes people to commit them. D.H. Mellor shows us that to understand the world and our lives we must understand causation. _The Facts of Causation_, now available in paperback, is essential reading for students and for anyone interested in reading one of the ground-breaking theories in metaphysics. We cannot understand the world and our (...) place in it without understanding causation. Yet a complete account of the nature and implications of causation does not exist. D.H Mellor's new book is that account. (shrink)

It might be expected that it would suffice for the entry for “moral anti-realism” to contain only some links to other entries in this encyclopedia. It could contain a link to “moral realism” and stipulate the negation of the view there described. Alternatively, it could have links to the entries “anti-realism” and “morality” and could stipulate the conjunction of the materials contained therein. The fact that neither of these approaches would be adequate—and, more strikingly, that following the two procedures would (...) yield substantively non-equivalent results—reveals the contentious and unsettled nature of the topic. -/- “Anti-realism,” “non-realism,” and “irrealism” may for most purposes be treated as synonymous. Occasionally, distinctions have been suggested for local pedagogic reasons (see, e.g., Wright 1988a; Dreier 2004), but no such distinction has generally taken hold. (“Quasi-realism” denotes something very different, to be discussed in the supplement Projectivism and quasi-realism below.) All three terms are to be defined in opposition to realism, but since there is no consensus on how “realism” is to be understood, “anti-realism” fares no better. Crispin Wright (1992: 1) comments that “if there ever was a consensus of understanding about ‘realism’, as a philosophical term of art, it has undoubtedly been fragmented by the pressures exerted by the various debates—so much so that a philosopher who asserts that she is a realist about theoretical science, for example, or ethics, has probably, for most philosophical audiences, accomplished little more than to clear her throat.” This entry doesn't purport to do justice to the intricacy and subtlety of the topic of realism; it should be acknowledged at the outset that the fragmentation of which Wright speaks renders it unlikely that the label “moral anti-realism” even succeeds in picking out a definite position. Yet perhaps we can at least make an advance on clearing our throats. (shrink)

'Why did the window break when it was hit by the stone? Because the window is brittle and the stone is hard; hardness and brittleness are powers, dispositional properties or dispositions.' Dispositions are essential to our understanding of the world. This book is a record of the debate on the nature of dispositions between three distinguished philosophers - D. M. Armstrong, C. B. Martin and U. T. Place - who have been thinking about dispositions all their working lives. Their distinctive (...) accounts cover many of the issues surrounding dispositions such as the nature of mind, matter, universals, existence, laws of nature and causation. Dispositions illuminates this central topic in analytic philosophy and at the same time highlights deeper concerns of metaphysics. (shrink)

This paper argues that the concept and role of ‘institutional racism’ in contemporary discussions of race should be reconsidered. It starts by distinguishing between ‘intrinsic institutional racism’, which holds that institutions are racist in virtue of their constitutive features, and ‘extrinsic institutional racism’, which holds that institutions are racist in virtue of their negative effects. It accepts intrinsic institutional racism, but argues that a ‘disparate impact’ conception of extrinsic conception faces a number of objections, the most serious being that it (...) has no plausible account of what it is that makes extrinsically racist institutions racist. It also argues that claims about the explanatory indispensability of institutional racism are overstated (individual racism is at least as important), critiques structural approaches to racial inequality, and suggests that there is reason to doubt whether institutional reform can provide us with all that morality may require in the racial domain. (shrink)

Teleological terms such as "function" and "design" appear frequently in the biological sciences. Examples of teleological claims include: A (biological) function of stotting by antelopes is to communicate to predators that they have been detected. Eagles' wings are (naturally) designed for soaring. Teleological notions were commonly associated with the pre-Darwinian view that the biological realm provides evidence of conscious design by a supernatural creator. Even after creationist viewpoints were rejected by most biologists there remained various grounds for concern about the (...) role of teleology in biology, including whether such terms are: 1. vitalistic (positing some special "life-force"); 2. requiring backwards causation (because future outcomes explain present traits); 3. incompatible with mechanistic explanation (because of 1 and 2); 4. mentalistic (attributing the action of mind where there is none); 5. empirically untestable (for all the above reasons). Opinions divide over whether Darwin's theory of evolution provides a means of eliminating teleology from biology, or whether it provides a naturalistic account of the role of teleological notions in the science. Many contemporary biologists and philosophers of biology believe that teleological notions are a distinctive and ineliminable feature of biological explanations but that it is possible to provide a naturalistic account of their role that avoids the concerns above. Terminological issues sometimes serve to obscure some widely-accepted distinctions. (shrink)

This article endeavors to identify the strongest versions of the two primary arguments against epistemic scientific realism: the historical argument—generally dubbed “the pessimistic meta-induction”—and the argument from underdetermination. It is shown that, contrary to the literature, both can be understood as historically informed but logically validmodus tollensarguments. After specifying the question relevant to underdetermination and showing why empirical equivalence is unnecessary, two types of competitors to contemporary scientific theories are identified, both of which are informed by science itself. With the (...) content and structure of the two nonrealist arguments clarified, novel relations between them are uncovered, revealing the severity of their collective threat against epistemic realism and its “no-miracles” argument. The final section proposes, however, that the realist’s axiological tenet “science seeks truth” is not blocked. An attempt is made to indicate the promise for a nonepistemic, purely axiological scientific realism—here dubbed “Socratic scientific realism.”. (shrink)

In The Quantum Self, Danah Zohar argues that the insights of modem physics can illuminate our understanding of everyday life -- our relationships to ourselves, to others, and to the world at large. Guiding us through the strange and fascinating workings of the subatomic realm to create a new model of human consciousness, the author addresses enduring philosophical questions. Does the new physics provide a basis by which our consciousness might continue beyond death? How does the material world (for instance, (...) ugly inner cities) impinge upon our sense of self? Is there a subatomic wellspring from which our creativity, our empathy with others, and our feelings of unity with the inanimate world originate?Most important, Zohar shows how the vitality of the new physics combats the alienation and fragmentation of twentieth-century life, and replaces it with a model of reality in which the universe itself may possess a type of consciousness, of which human consciousness is one expression. (shrink)

Objective—To determine the prevalence of, and attitudes towards, observed and personal research misconduct among newly appointed medical consultants. Design—Questionnaire study.Setting—Mersey region, United Kingdom.Participants—Medical consultants appointed between Jan 1995 and Jan 2000 in seven different hospital trusts (from lists provided by each hospital's personnel department). Main outcome measures—Reported observed misconduct, reported past personal misconduct and reported possible future misconduct.Results—One hundred and ninety-four replies were received (a response rate of 63.6%); 55.7% of respondents had observed some form of research misconduct; 5.7% of (...) respondents admitted to past personal misconduct; 18% of respondents were either willing to commit or unsure about possible future research misconduct. Only 17% of the respondents reported having received any training in research ethics. Anaesthetists reported a lower incidence of observed research misconduct (33.3%) than the rest of the respondents (61.5%) (p<0.05). Conclusion—There is a higher prevalence of observed and possible future misconduct among newly appointed consultants in the UK than in the comparable study of biomedical trainees in California. Although there is a need for more extensive studies, this survey suggests that there is a real and potential problem of research misconduct in the UK. (shrink)

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience associated with remembering the past and imagining the future. Participants mentally “re-experienced” or “pre-experienced” positive and negative events that differed in their temporal distance from the present , and then rated the phenomenal characteristics associated with their representations. For both past and future, representations of positive events were associated with a greater feeling of (...) re-experiencing than representations of negative events. In addition, representations of temporally close events contained more sensorial and contextual details, and generated a stronger feeling of re-experiencing than representations of temporally distant events. It is suggested that the way we both remember our past and imagine our future is constrained by our current goals. (shrink)

It was proposed that the data from Monte Carlo statistical investigations be subjected to analysis of variance methods rather than the conventional techniques of tabling, graphing, and inspecting the data. Two examples in which analysis of variance methods were applied to published Monte Carlo studies were presented. It was suggested that balanced factorial designs should be used whenever possible in Monte Carlo studies so that analysis of variance methods would be directly applicable. Finally, three advantages of analysis of variance methods (...) over conventional techniques were described and analysis of variance methods were contrasted with a possible alternative analytical method, multiple regression analysis. (shrink)