Pediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrolls in a trial during treatment. This paper discusses the ethical consequences of the unprecedented integration of research and care in pediatric oncology from the perspective of parents and physicians. An empirical ethical approach, combining (1) a narrative review of (primarily) qualitative studies on parents' and physicians' experiences of the pediatric (...) oncology research practice, and (2) comparison of these experiences with existing theoretical ethical concepts about (pediatric) research. The use of empirical evidence enriches these concepts by taking into account the peculiarities that ethical challenges pose in practice. Analysis of the 22 studies reviewed revealed that the integration of research and care has consequences for the informed consent process, the promotion of the child's best interests, and the role of the physician (doctor vs. scientist). True consent to research is difficult to achieve due to the complexity of research protocols, emotional stress and parents' dependency on their child's physician. Parents' role is to promote their child's best interests, also when they are asked to consider enrolling their child in a trial. Parents are almost never in equipoise on trial participation, which leaves them with the agonizing situation of wanting to do what is best for their child, while being fearful of making the wrong decision. Furthermore, a therapeutic misconception endangers correct assessment of participation, making parents inaccurately attribute therapeutic intent to research procedures. Physicians prefer the perspective of a therapist over a researcher. Consequently they may truly believe that in the research setting they promote the child's best interests, which maintains the existence of a therapeutic misconception between them and parents. Due to the integration of research and care, their different ethical perspectives become intertwined in the daily practice of pediatric oncology. Increasing awareness of what this means for the communication between parents and physicians is essential. Future research should focus on efforts that overcome the problems that the synchronicity of research and care evokes. (shrink)

According to Fondane, rationalist philosophy implies arguments that aim at a separation of the intelligible and the sensible which, in the Platonic tradition represents a degradation of the de-signified individual. Supporting itself on Lévinas’ thematization of the ethical as a prime philosophy, the interpretation regards the nucleus of the strong relation between morality and religion. Following the Christic example, the moment man is emptied of himself, he may free himself from his fake central placing. A radical passivity of a de-moralized (...) conscience that, having nothing to do, gives itself to the Good from before its possibility of choosing it. A humiliated ethics, invisible to transcendence, in the light of which it is not primordial to do something good, but to let oneself be made by the immemorial Good. (shrink)

We investigated the effect of culture, moral discourse, and motivation to engage in prosocial behavior on benefactors’ positive affect. Participants from three cultures responded to scenarios in which they could perform small acts of kindness for different targets. A stronger relationship between agentic and obligated motivation to perform acts of kindness, as well as between obligated motivation and positive affect, was observed for participants from Japan, and for individuals with higher endorsement of the Community Ethic. Agentic motivation to engage in (...) prosocial behavior was related to benefactors’ positive affect, regardless of relationship type. (shrink)

There has been considerable debate on how to teach ethics within the marketing curriculum to accommodate the AACSB requirements requiring emphasis on ethical issues within the business curricula. Since introducing a separate course on marketing ethics has limited reach, we propose incorporating the ethical dimension through guest speeches and reflective learning in a mandatory Marketing course for all business majors. Through phenomenographic analysis of 121 student reflections, we report evidence supporting the effectiveness of this approach in significantly raising awareness of (...) ethics in the marketing domain and in initiating the nurturing of ethical reasoning abilities in undergraduate business students early in their college careers. Students absorbed substantial amounts of knowledge at different levels and demonstrated significant cognitive processing within the revised Bloom’s taxonomy. Using this method to teach marketing ethics promotes awareness and application of ethical reasoning without compromising disciplinespecific instruction. (shrink)

The common opinion has been that evolution results in the continuing development of more complex forms of life, generally understood as more complex organisms. The arguments supporting that opinion have recently come under scrutiny and been found wanting. Nevertheless, the appearance of increasing complexity remains. So, is there some sense in which evolution does grow complexity? Artificial life simulations have consistently failed to reproduce even the appearance of increasing complexity, which poses a challenge. Simulations, as much as scientific theories, are (...) obligated at least to save the appearances! We suggest a relation between these two problems, understanding biological complexity growth and the failure to model even its appearances. We present a different understanding of that complexity which evolution grows, one that genuinely runs counter to entropy and has thus far eluded proper analysis in information-theoretic terms. This complexity is reflected best in the increase in niches within the biosystem as a whole. Past and current artificial life simulations lack the resources with which to grow niches and so to reproduce evolution’s complexity. We propose a more suitable simulation design integrating environments and organisms, allowing old niches to change and new ones to emerge. (shrink)

PurposeThis paper aims to demonstrate the relevance of worldviews of the global south to debates of artificial intelligence, enhancing the human rights debate on artificial intelligence (AI) and critically reviewing the paper of UNESCO Commission on the Ethics of Scientific Knowledge and Technology (COMEST) that preceded the drafting of the UNESCO guidelines on AI. Different value systems may lead to different choices in programming and application of AI. Programming languages may acerbate existing biases as a people’s worldview is captured in (...) its language. What are the implications for AI when seen from a collective ontology? Ubuntu (I am a person through other persons) starts from collective morals rather than individual ethics.Design/methodology/approachLiterature overview on the African philosophy of Ubuntu as applied to artificial intelligence. Application of it to the United Nations Educational, Scientific and Cultural Organisation (UNESCO) debates on establishing guidelines to the ethics of artificial intelligence.FindingsMetaphysically, Ubuntu and its conception of social personhood (attained during one’s life) largely rejects transhumanism. When confronted with economic choices, Ubuntu favors sharing above competition and thus an anticapitalist logic of equitable distribution of AI benefits, humaneness and nonexploitation. When confronted with issues of privacy, Ubuntu emphasizes transparency to group members, rather than individual privacy, yet it calls for stronger (group privacy) protection. In democratic terms, it promotes consensus decision-making over representative democracy. Certain applications of AI may be more controversial in Africa than in other parts of the world, like care for the elderly, that deserve the utmost respect and attention, and which builds moral personhood. At the same time, AI may be helpful, as care from the home and community is encouraged from an Ubuntu perspective. The report on AI and ethics of the UNESCO World COMEST formulated principles as input, which are analyzed from the African ontological point of view. COMEST departs from “universal” concepts of individual human rights, sustainability and good governance which are not necessarily fully compatible with relatedness, including future and past generations. Next to rules based approaches, which may hamper diversity, bottom-up approaches are needed with intercultural deep learning algorithms.Research limitations/implicationsThere is very few existing literature on AI and Ubuntu. Therefore, this paper is of an explorative nature.Practical implicationsThe ethics of Ubuntu offers unique vantage points in looking at the organization of society and economics today, which are also relevant for development of AI, especially in its tenet of relatedness rather than individuality (and practical use of AI for individuals), taking responsibility for society as a whole (such as analyzing the benefit of AI for all strata of society), and embodying true inclusiveness. Whether looking at top-down guidelines for the development and implementation of AI or the bottom-up ethical learning process of AI (deep learning), ethics of the Global South can have an important role to play to combat global individualist tendencies and inequity, likely reinforced by AI. This warrants far more research.Social implicationsApplications of AI in Africa are not contextualized, do not address the most pressing needs of the African continent, lead to cybersecurity issues and also do not incorporate African ethics. UNESCO’s work in this regard is important but expert inputs are largely centered around Western “universal” principles and Organisation for Economic Cooperation and Development and EU precedence. African ethics have, so far, a small role to play in global ethics and philosophy and therefore risk to be overlooked in the discussion on AI and ethics. This is why the consultation process of UNESCO on ethics of AI was of paramount importance. However, it does not automatically lead to consultation of African philosophers or sages, as many are educated in Western (ized) education systems. See further details under practical implications.Originality/valueThis is a new area of research in which little work has been done so far. This paper offers the opportunity to widen the debate on AI and ethics beyond the conventional discourse, involving multiple worldviews, of which Ubuntu is just one. (shrink)

Developmental coordination disorder is a heterogeneous condition. Besides motor impairments, children with DCD often exhibit poor visual perceptual skills and executive functions. This study aimed to characterize the motor, perceptual, and cognitive profiles of children with DCD at the group level and in terms of subtypes. A total of 50 children with DCD and 31 typically developing peers underwent a comprehensive neuropsychological and motor assessment. The percentage of children with DCD showing impairments in each measurement was first described. Hierarchical agglomerative (...) and K-means iterative partitioning clustering analyses were then performed to distinguish the subtypes present among the complete sample of children in a data-driven way. Moderate to large percentages of children with DCD showed impaired executive functions and praxis, as well as attentional, visual perceptual, and visuomotor skills. Clustering analyses identified five subtypes, four of them mainly consisting of children with DCD and one of TD children. These subtypes were characterized by: generalized impairments, impaired manual dexterity, poor balance, planning, and alertness, impaired manual dexterity, cognitive inhibition, and poor visual perception, impaired manual dexterity and cognitive inhibition, and no impairment. Besides subtle differences, the motor and praxis measures did not enable to discriminate between the four subtypes of children with DCD. The subtypes were, however, characterized by distinct perceptual or cognitive impairments. These results highlight the importance of assessing exhaustively the perceptual and cognitive skills of children with DCD. (shrink)

While the recognition of ambiguous emotions is crucial for successful social interactions, previous work has shown that they are perceived differently depending on whether they are viewed on male or female faces. The present paper aims to shed light on this phenomenon by exploring two hypotheses: the confounded signal hypothesis, which posits the existence of perceptual overlaps between emotions and gendered morphotypes, and the social role hypothesis, according to which the observer's responses are biased by stereotypes. Participants were asked to (...) categorise blended faces (i.e. artificial faces made ambiguous by mixing two emotions) in a forced-choice task. Six emotions were used to create each blend (neutral, surprise, sadness, fear, happiness, anger), for a total of 15 expressions. We then applied signal detection theory – considering both the morphotype of the stimuli and the participants’ gender – to distinguish participants’ perceptual processes from their response biases. The results showed a perceptual advantage for anger on male faces and for sadness on female faces. However, different strategies were deployed when labelling emotions on gendered morphotypes. In particular, a response bias towards angry male faces establishes their special status, as they resulted in both excellent detection and a tendency to be over-reported, especially by women. (shrink)

Over the past 20 years, along with official endeavors directed towards the accession of Romania into the European structures, political parties tried to integrate themselves into wider European families. Approaching the European People’s Party (the most prominent group in the European Parliament) - dominated by Christian democrats whose existence was largely influenced by the Catholic social teaching - seemed to be one of the most difficult tasks. For their first European elections held in 2007 several Romanian political parties - apart (...) from the National Christian Democrat Peasant Party (a member of the European Christian Democratic Union since 1987) - changed their orientation and claimed themselves as Christian Democratic. This article intends to explore the extent to which Romanian political parties who assert themselves as Christian-democratic can be considered to belong to this political family or whether their claim has a rather administrative motivation. (shrink)

This commentary focuses on the limitations of the E-Z Reader model in its attempt to explain refixation saccades in reading. Listing factors that influence probability of refixating leads the model to assume two sorts of refixations. However, taking into account data on the metrics of refixation saccades allows us to propose an alternative explanation for empirical observations reported in the literature.

Sebastian Şebu, Monica Opriş, Dorin Opriş, Metodica predării religiei (Methodology of Teaching Religion) Reîntregirea Publishing House, Alba Iulia, 2000.

'You're 82 years old. You've shrunk six centimetres, you only weigh 45 kilos yet you're still beautiful, graceful and desirable' – so begins André Gorz's 'open love letter' to the woman he has lived with for 58 years and who lies dying next to him. As one of France's leading post-war philosophers, André Gorz wrote many influential books, but nothing he wrote will be read as widely or remembered as long as this simple, passionate, beautiful letter to his dying wife. (...) In a bittersweet postscript a year after Letter to D was published, a note pinned to the door for the cleaning lady marked the final chapter in an extraordinary love story. André Gorz and his terminally ill wife, Dorine, were found lying peacefully side by side, having taken their lives together. They simply could not live without one another. An international bestseller, _Letter to D_ is the ultimate love story – and all the more poignant because it's true. (shrink)