In recent years, exposome research has been put forward as the next frontier for the study of human health and disease. Exposome research entails the analysis of the totality of environmental exposures and their corresponding biological responses within the human body. Increasingly, this is operationalized by big-data approaches to map the effects of internal as well as external exposures using smart sensors and multiomics technologies. However, the ethical implications of exposome research are still only rarely discussed in the literature. Therefore, (...) we conducted a systematic review of the academic literature regarding both the exposome and underlying research fields and approaches, to map the ethical aspects that are relevant to exposome research. We identify five ethical themes that are prominent in ethics discussions: the goals of exposome research, its standards, its tools, how it relates to study participants, and the consequences of its products. Furthermore, we provide a number of general principles for how future ethics research can best make use of our comprehensive overview of the ethical aspects of exposome research. Lastly, we highlight three aspects of exposome research that are most in need of ethical reflection: the actionability of its findings, the epidemiological or clinical norms applicable to exposome research, and the meaning and action–implications of bias. (shrink)

Computational modeling has long been one of the traditional pillars of cognitive science. Unfortunately, the computer models of cognition being developed today have not kept up with the enormous changes that have taken place in computer technology and, especially, in human-computer interfaces. For all intents and purposes, modeling is still done today as it was 25, or even 35, years ago. Everyone still programs in his or her own favorite programming language, source code is rarely made available, accessibility of models (...) to non-programming researchers is essentially non-existent, and even for other modelers, the profusion of source code in a multitude of programming languages, written without programming guidelines, makes it almost impossible to access, check, explore, re-use, or continue to develop. It is high time to change this situation, especially since the tools are now readily available to do so. We propose that the modeling community adopt three simple guidelines that would ensure that computational models would be accessible to the broad range of researchers in cognitive science. We further emphasize the pivotal role that journal editors must play in making computational models accessible to readers of their journals. (shrink)

Elliott Currie, Confronting Crime: An American Challenge New York: Pantheon Books, 1985, viii + 326 pp.

This paper addresses Joseph Heath’s attempt to derive moral obligations from the conditions that are specified by the model of the perfectly competitive market. Through his market failures approach to business ethics he argues that firms should behave as if they are operating in a perfectly competitive market. However, I argue that this derivation of moral obligations runs counter to the metaethical principle that moral actions need to be voluntarily chosen from a set of alternatives. To the extent that Milton (...) Friedman’s derivation follows the same lines, my objection is also applicable to his approach to business ethics. I bring out the fact that the conditions required by the model of the perfectly competitive market cannot be realized in the actual world and argue that this causes problems for any moral obligations that might follow. My objection is illustrated by an intuitive example of someone set to an impossible task. I also bring in a way that Heath could work around this objection, but I argue that this would imply the collapse of his approach into another kind of theory that he wishes to distinguish himself from. More deeply, I show that my metaethical objection has epistemological consequences that undermine the very basis of the model of the perfectly competitive market. I conclude by stating that we need a different conception of competition, pointing to the facts that such a perspective would need to take into account, and suggesting that the concept of rivalry is up to the job. (shrink)

Exposome research is put forward as a major tool for solving the nature-versus-nurture debate because the exposome is said to represent “the nature of nurture.” Against this influential idea, we argue that the adoption of the nature-versus-nurture debate into the exposome research program is a mistake that needs to be undone to allow for a proper bioethical assessment of exposome research. We first argue that this adoption is originally based on an equivocation between the traditional nature-versus-nurture debate and a debate (...) about disease prediction/etiology. Second, due to this mistake, exposome research is pushed to adopt a limited conception of agential control that is harmful to one's thinking about the good that exposome research can do for human health and wellbeing. To fully excise the nature-versus-nurture debate from exposome research, we argue that exposome researchers and bioethicists need to think about the exposome afresh from the perspective of actionability. We define the concept of actionability and related concepts and show how these can be used to analyze the ethical aspects of the exposome. In particular, we focus on refuting the popular “gun analogy” in exposome research, returning results to study participants and risk-taking in the context of a well-lived life. (shrink)

It is now standard to interpret symmetry-related models of physical theories as representing the same state of affairs. Recently, a debate has sprung up around the question when this interpretational move is warranted. In particular, Møller-Nielsen :1253–1264, 2017) has argued that one is only allowed to interpret symmetry-related models as physically equivalent when one has a characterisation of their common content. I disambiguate two versions of this claim. On the first, a perspicuous interpretation is required: an account of the models’ (...) common ontology. On the second, stricter, version of this claim, a perspicuous formalism is required in addition: one whose mathematical structures ‘intrinsically’ represent the physical world, in the sense of Field. Using Dewar’s :485–521, 2019) distinction between internal and external sophistication as a case study, I argue that the second requirement is decisive. This clarifies the conditions under which it is warranted to interpret symmetry-related models as physically equivalent. (shrink)

The presence of symmetries in physical theories implies a pernicious form of underdetermination. In order to avoid this theoretical vice, philosophers often espouse a principle called Leibniz Equivalence, which states that symmetry-related models represent the same state of affairs. Moreover, philosophers have claimed that the existence of non-trivial symmetries motivates us to accept the Invariance Principle, which states that quantities that vary under a theory’s symmetries aren’t physically real. Leibniz Equivalence and the Invariance Principle are often seen as part of (...) the same package. I argue that this is a mistake: Leibniz Equivalence and the Invariance Principle are orthogonal to each other. This means that it is possible to hold that symmetry-related models represent the same state of affairs whilst having a realist attitude towards variant quantities. Various arguments have been presented in favour of the Invariance Principle: a rejection of the Invariance Principle is inter alia supposed to cause indeterminism, undetectability or failure of reference. I respond that these arguments at best support Leibniz Equivalence. (shrink)

ABSTRACT In this journal, Middleton and Murgueitio Ramírez argue that absolute velocity is measurable, contrary to the received wisdom. Specifically, they claim that ‘there exists at least one reasonable analysis of measurement according to which the speedometer in [a world called “the Basic World”] measures the absolute velocity of the car.’ In this note, I critically respond to that claim: the analysis of measurement that Middleton and Murgueitio Ramírez propose is not reasonable; nor does it entail that absolute velocities are (...) measurable. (shrink)

Shifts are a well-known feature of the literature on spacetime symmetries. Recently, discussions have focused on so-called dynamic shifts, which by analogy with static and kinematic shifts enact arbitrary linear accelerations of all matter (as well as a change in the gravitational potential). But in mathematical formulations of these shifts, the analogy breaks down: while static and kinematic shift act on the matter field, the dynamic shift acts on spacetime structure instead. I formulate a different, `active' version of the dynamic (...) shift which does act on matter. (shrink)

In 1436, Leon Battista Alberti wrote a letter to Filippo Brunelleschi, which he attached to a manuscript of his recently completed treatise on painting, De pictura. In it, Alberti lauded some of the Florentine artists of his day, singling out Brunelleschi for particular praise on account of the unprecedented engineering feat of constructing the cupola of the Florentine cathedral of Santa Maria del Fiore. This article undertakes a close reading of some parts of the letter, focusing especially on the link (...) that Alberti draws between great intellects and giants. Exploring the cultural traditions that might have informed Alberti’s thinking—in particular, canto XXXI of Dante’s Inferno —the article considers how the giants introduce an element of moral jeopardy, significantly complicating what might otherwise appear to be a purely celebratory text. This sense of ambivalence is further explored in relation to the ‘long exile’ from which Alberti says that his family had recently returned. Similar phrases appear in Virgil’s Aeneid and Ovid’s Metamorphoses, and consideration of these poems, it is argued, might further inflect our understanding of Alberti’s words in the letter. In this way, the article investigates how Alberti employed sophisticated literary means in order to express his own feelings regarding Brunelleschian ingegno and technical mastery; feelings that were both highly nuanced and, ultimately, unsettled. (shrink)

(No abstract is available for this citation).

Ruetsche ([2011]) argues that the occurrence of unitarily inequivalent representations in quantum theories with infinitely many degrees of freedom poses a novel interpretational problem. According to Ruetsche, such theories compel us to reject the so-called ideal of pristine interpretation; she puts forward the ‘coalescence approach’ as an alternative. In this paper I offer a novel defence of the coalescence approach. The defence rests on the claim that the ideal of pristine interpretation already fails before one considers the peculiarities of QM∞: (...) there are pre-QM∞ parallels to coalescence. Despite this departure from pristinism, the ‘modest’ view that emerges poses no threat to scientific realism. (shrink)

The distinction between dimensions and units in physics is commonplace. But are dimensions a feature of reality? The most widely-held view is that they are no more than a tool for keeping track of the values of quantities under a change of units. This anti-realist position is supported by an argument from underdetermination: one can assign dimensions to quantities in many different ways, all of which are empirically equivalent. In contrast, I defend a form of dimensional realism, on which some (...) assignments of dimensions to quantities better describe reality than others. The argument I provide is a form of inference to the best explanation. In particular, the technique of dimensional analysis is explanatory, but it is only successful for certain systems of dimensions. Since these dimensional systems support scientific explanations, we have reason to believe that they are real. (shrink)

Caspar Hare makes an original and compelling case for "egocentric presentism," a view about the nature of first-person experience, about what happens when we see things from our own particular point of view. A natural thought about our first-person experience is that "all and only the things of which I am aware are present to me." Hare, however, goes one step further and claims, counterintuitively, that the thought should instead be that "all and only the things of which I (...) am aware are present." There is, in other words, something unique about me and the things of which I am aware. On Myself and Other, Less Important Subjects represents a new take on an old view, known as solipsism, which maintains that people's experiences give them grounds for believing that they have a special, distinguished place in the world--for example, believing that only they exist or that other people do not have conscious minds like their own. Few contemporary thinkers have taken solipsism seriously. But Hare maintains that the version of solipsism he argues for is in indeed defensible, and that it is uniquely capable of resolving some seemingly intractable philosophical problems--both in metaphysics and ethics--concerning personal identity over time, as well as the tension between self-interest and the greater good. This formidable and tightly argued defense of a seemingly absurd view is certain to provoke debate. (shrink)

This is about the rights and wrongs of bringing people into existence. In a nutshell: sometimes what matters is not what would have happened to you, but what would have happened to the person who would have been in your position, even if that person never actually exists.

Caspar Hare presents a bold and original approach to questions of what we ought to do, and why we ought to do it. He breaks with tradition to argue that we can tackle difficult problems in normative ethics by starting with a principle that is humble and uncontroversial. Being moral involves wanting particular other people to be better off.

Physics presents us with a symphony of natural constants: G, h, c, etc. Up to this point, constants have received comparatively little philosophical attention. In this paper I provide an account of dimensionful constants, in particular the gravitational constant. I propose that they represent inter-quantity structure in the form of relations between quantities with different dimensions. I use this account of G to settle a debate over whether mass scalings are symmetries of Newtonian Gravitation. I argue that they are not, (...) but only if we interpret mass anti-quidditistically. This is analogous to anti-haecceitism in the presence of spacetime symmetries. (shrink)

- Emilie du Châtelet offers an interesting and unusual account of the origin of our representation of extension. - She is an idealist about the essence extension, bodies and space, regarding them as mental constructs. - Du Châtelet's account requires a brute fact about the mind, in apparent tension with the Principle of Sufficient Reason.

In this dissertation I spell out, and make a case for, egocentric presentism, a view about what it is for a thing to be me. I argue that there are benefits associated with adopting this view. ;The chief benefit comes in the sphere of ethics. Many of us, when we think about what to do, feel a particular kind of ambivalence. On the one hand we are moved by an impartial concern for the greater good. We feel the force of (...) considerations of the form: 'all things considered, doing...will make things better overall'. On the other hand we are selfish. We feel the force of considerations of the form 'doing...will make things better for me.' And it appears as if these sorts of considerations often conflict. Often by doing what makes things better for me I do not make things better overall, and vice-versa. But egocentric presentism is capable of resolving this conflict. As an egocentric presentist I can think both that considerations of the greater good always count in favor my doing what's good for me, and that considerations of the greater good always count in favor of other people doing what's good for them. ;Another benefit comes in the sphere of metaphysics. As an egocentric presentist I can make sense of some otherwise perplexing puzzles about personal identity over time, by combining a non-reductionist view about who I will be, with Parfitian reductionism about personal identity over time and a lean physicalist ontology. (shrink)

Dans Le Plaisir et la Nécessité, Pierre-Marie Morel (= M.) réunit des articles presque tous déjà publiés (neuf sur dix) au cours des vingt dernières années et traitant de multiples sujets abordés par deux philosophes qu’il connaît magistralement, Démocrite et épicure. Le livre est composé d’une introduction suivie de dix chapitres articulés en trois parties, d’un épilogue, de remerciements et d’une bibliographie sélective structurée. Il se termine par deux index témoignant de l’ampleur et de...

Some moral theories tell you, in some situations in which you are interacting with a group of people, to avoid acting in the way that is expectedly best for everybody. This essay argues that such theories are mistaken. Go ahead and do what is expectedly best for everybody. The argument is based on the thought that when interacting with an individual it is fine for you to act in the expected interests of the individual and that many interactions with individuals (...) may compose an interaction with a group. (shrink)

CASPAR: JOHANNES KEPLERS WISSENSCH. PHIL. STEL. SC 13 E-BOOK.

It is natural to distinguish between objective and subjective senses of.

It is often claimed that one can avoid the kind of underdetermination that is a typical consequence of symmetries in physics by stipulating that symmetry-related models represent the same state of affairs (Leibniz Equivalence). But recent commentators (Dasgupta 2011; Pooley 2021; Pooley and Read 2021; Teitel 2021a) have responded that claims about the representational capacities of models are irrelevant to the issue of underdetermination, which concerns possible worlds themselves. In this paper I distinguish two versions of this objection: (1) that (...) a theory’s formalism does not (fully) determine the space of physical possibilities, and (2) that the relevant notion of possibility is not physical possibility. I offer a refutation of each. (shrink)

In this chapter on time‐the emotional asymmetry, the author addresses two questions concerning future‐bias. The first is with respect to the sorts of things are people future‐biased. Do people want all things that they regard as bad to be in the past, or just some of them? Second, are people justified in being future‐biased? The second question has received a good deal of attention from philosophers. The author aims to survey different answers to the question, and to give a sense (...) of how things presently lie. A section presents some poor arguments for future‐bias, including discussions on the shrinking block theory of time. It is also said that, even if four‐dimensionalism is false, a charge of arbitrariness can be leveled at future‐bias. Finally, the chapter presents a discussion on some incoherence arguments against future‐bias. (shrink)

This is about the metaphysics of the self and ethical egoism. It can serve as a preview for my manuscript-in-progress below.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:A Field on Fire: The Future of Environmental History ed. by Mark D. Hersey and Ted SteinbergJeff HirschyA Field on Fire: The Future of Environmental History EDITED BY MARK D. HERSEY AND TED STEINBERG Tuscaloosa: The University of Alabama Press, 2019In the beginning, there was something. Usually filled in with more details, the phrase “in the beginning” is a universal phrase that can cross academic fields, religions, governments, (...) works of literature, and many other things. In A Field on Fire: The Future of Environmental History, the “in the beginning” is used to refer to the works of famed environmental historian Donald Worster. Using Worster’s writings as a guide, editors Mark D. Hersey and Ted Steinberg use their contributors to lead readers through an examination of the past, present, and future of the field of environmental history.The concepts from Worster that Hersey and Steinberg organize their work around include the problems of natural limits, the transnational nature of environmental issues, and questions regarding method. This framework allows the editors and contributors to examine the relationship between democracy, capitalism, technology, and the environment; the ways that environmental history can and should cross borders; and the tools and the methods of the field. The framework built around Worster’s writings allows for a rich examination of environmental history and shows that many of the ideas that Worster pioneered almost forty years ago are still valid and important.A Field on Fire is divided into three sections containing six, six, and five chapters, respectively. The first section focuses on the relationship between capitalism, the environment, and technology. The second focuses on the international nature of environmental history. The third focuses on the ways that environmental history, including its methods and tools, can be useful in other fields. Together, all three sections [End Page 133] show the richness of environmental history and the influence Worster has had, and still has, on the field.The first section of the book focuses on ideas like resource use, capitalism, and the radical roots of the field. It is driven by Worster’s desire to “get out of parliamentary chambers, out of the birthing rooms and factories, get out of doors altogether, and ramble into the fields, woods, and the open air” (2). The contributors use Worster has a guide to “get out” and examine environmental history and concepts across the United States. They show that environmental history does, in fact, have radical roots dating back to the late 1960s and early 1970s, that capitalism was the lens through which the United States usually engaged with nature, and that humans will continue to have an influence on nature in the United States and around the world. For example, in chapter 3 Frank Zelko writes, “Changing historical interpretations of humans’ impact on landscapes and ecosystems, as well as a willingness among scholars to write histories on a large spatial and temporal scale, have also contributed significantly to the managerial worldview of the Anthropocene” (49). All the authors of this section show that the field of environmental history is an important one for the changing environmental, cultural, economic, and political conditions in the United States in the early 21st century.Section two of A Field on Fire travels outside the United States and shows that Worster’s wish to create a field that could more easily cut across national borders to both enrich the field and its readers is alive and well. This section shows how examinations of things and ideas in many places, like Abaca fiber (chapter 7) or human migration (chapter 10), can tell a complex and often transnational story that can shed historical light on often overlooked ideas, peoples, and concepts. The contributors in this section show that environmental history should consider things such as migrant history, nationalism, race, and economic history. These contributors show that Worster’s ideas have merit and are taking flight in the early 21st century. Take, for example, the idea that immigrants and colonists traveling around the world take their own ideas about nature with them. This simple individual and collective act shows the transnational nature of this and many other aspects of environmental history. [End... (shrink)

This little book provides basic 7-minute yoga exercises for each day of the week. The exercises are organized by the mythological and planetary significances of each particular day.

We start by presenting three different views that jointly imply that every person has many conscious beings in their immediate vicinity, and that the number greatly varies from person to person. We then present and assess an argument to the conclusion that how confident someone should be in these views should sensitively depend on how massive they happen to be. According to the argument, sometimes irreducibly de se observations can be powerful evidence for or against believing in metaphysical theories.

Recently, Dewar (2019) has suggested that one can apply the strategy of 'sophistication' - as exemplified by sophisticated substantivalism as a response to the diffeomorphism invariance of General Relativity - to gauge theories such as electrodynamics. This requires a shift to the formalism of fibre bundles. In this paper, I develop and defend this suggestion. Where my approach differs from previous discussions is that I focus on the metaphysical picture underlying the fibre bundle formalism. In particular, I aim to affirm (...) the physical reality of gauge properties. I argue that this allows for a local and separable explanation of the Aharonov-Bohm effect. Its puzzling features are explained by a form of holism inherent to fibre bundles. (shrink)

It is nearly impossible to open a textbook on Newtonian mechanics without encountering the concept of inertial frames: the frames that are privileged by the theory’s dynamics. In this paper, I argue that extant definitions of inertial frames are unsatisfactory. I criticise two common definitions of inertial frames: law-based definitions, according to which inertial frames are simply those in which the laws are true, and structure-based definitions, according to which inertial frames are those that are ‘adapted’ to spatiotemporal structure. I (...) then offer a new, symmetry-based definition of inertial frames. This definition offers a non-conventional way of specifying the dynamically privileged frames. The result clarifies the foundations of Newtonian mechanics and accounts for the empirical success of coordinate-dependent formulations of it. (shrink)

Although physical theories routinely posit absolute quantities, such as absolute position or intrinsic mass, it seems that only comparative quantities such as distance and mass ratio are observable. But even if there are in fact only distances and mass ratios, the success of absolutist theories means that the world looks just as if there are absolute positions and intrinsic masses. If comparativism is nevertheless true, there is a sense in which it is a cosmic conspiracy that the world looks just (...) as if there are absolute quantities: the comparative quantities satisfy certain relations that only absolutism can explain. I show that such cosmic conspiracies are a pervasive feature of comparativist theories. The argument is structurally similar to the well-known No Miracles Argument for scientific realism. Just as anti-realism cannot explain the empirical adequacy of our theories in general, so comparativism cannot explain the empirical adequacy of absolutist theories in particular. (shrink)

Should we be time-biased on behalf of other people? 'Sometimes yes, sometimes no'—it is tempting to answer. But this is not right. On pain of irrationality, we cannot be too selective about when we are time-biased on behalf of other people.