The field of synthetic biology is looking forward engineering framework for safely designing reliable de-novo biological functions. In this undertaking, Computer-Aided-Design environments should play a central role for facilitating the design. Although, CAD environment is widely used to engineer artificial systems the application in synthetic biology is still in its infancy. In this article we address the problem of the design of a high level language which at the core of CAD environment. More specifically the Gubs language is a specification (...) language used to describe the observations of the expected behaviour. The compiler appropriately selects components such that the observation of the synthetic biological function resulting to their assembly complies to the programmed behaviour. (shrink)

Today, thanks to biomedical technologies advances, some persons with fertility issues can conceive. Transgender persons benefit also from these advances and can not only actualize their self-identified sexual identities but also experience parenthood. Based on clinical multidisciplinary seminars that gathered child psychiatrists and psychoanalysts interested in the fields of assisted reproduction technology and gender dysphoria, philosophers interested in bioethics, biologists interested in ART, and endocrinologists interested in pubertal suppression, we explore how new biotechnical advances, whether in gender transition or procreation, (...) could create new ways to conceive a child possible. After reviewing the various medical/surgical techniques for physical gender transition and the current ART options, we discuss how these new ways for persons to self-actualize and to experience parenthood can not only improve the condition of transgender persons but also introduce some elements of change in the habitual patterns of thinking especially in France. Finally, we discuss the ethical issues that accompany the arrival of these children and provide creative solutions to help society handle, accept, and support the advances made in this area. (shrink)

Résumé Témoignage d’une collaboration au sein des musées et réflexion sur l’exposition à partir de « extraits » présentée au musée Sainte-Croix de Poitiers en 1989, d’après les saisons de nicolas poussin au musée des Beaux-Arts de Nancy en 2003 et 2004, et la peinture de claude rutault expose celle de Jean Gorin au musée des Beaux-Arts de Nantes en 2008.

Cet ouvrage part d’un paradoxe apparent : la coexistence, dans la Cuba de la fin du xixe siècle, de mécanismes d’exclusion raciale et d’un discours inclusif, élément clé d’un nationalisme cubain a-racial et construit sur la fraternité raciale, prôné par le héros national José Martí. En effet, les luttes anticoloniales et l’émancipation des esclaves ont favorisé la consolidation idéologique de cet a-racialisme (racelessness), qui s’est effectuée au prix d’un silence racial, impliquant que tou...

Soeurs ennemies ou soeurs jumelles, servante et maîtresse ou compagnes de labeur, s'ignorant l'une l'autre ou unies au point de presque s'identifier, la foi et la raison entretiennent à l'évidence une relation intense et tumultueuse. N'est-ce pas justement au coeur du mouvement qui tantôt les rapproche tantôt les oppose que s'ajuste leur rapport? Plus que d'un état stable acquis une fois pour toutes il s'agit bien d'une dynamique, d'un processus. C'est cc que visent à montrer les essais réunis dans cc (...) livre, qui rassemble les fruits d'un colloque de théologie et de philosophie tenu à l'initiative du Studium de Philosophie de Chartres et de l'Institut de Théologie des Dombes, centres de formation de la Communauté du Chemin Neuf. (shrink)

Malgré une littérature fournie sur les marqueurs de discours, le cas de_ wait_ reste assez peu traité à ce jour. L’étude présente les arguments permettant de classer certains emplois de ce terme (non intégrés à la syntaxe de la phrase, et possédant une valeur pragmatique) en tant que marqueur de discours, et définit les contours de cet emploi. L’étude se donne également pour objectif de déterminer ses effets de sens en contexte, en se basant sur un corpus d’exemples issus du (...) COCA et du BNC. Le rôle du MD et le rôle de l’environnement linguistique doivent être distingués, ce qui conduit à rechercher la valeur fondamentale de _wait_ dans cet emploi pragmatique. Cette dernière n’est pas totalement étrangère à celle du terme lexical, mais réinvestie dans le domaine de la construction énonciative. Elle peut ainsi être décrite en termes de suspension de la construction énonciative, mise à profit dans le domaine des réajustements du discours. (shrink)

Personhood is ascribed on others, such that someone who is recognized to be a person is bestowed with certain civil rights and the right to decision making. A rising question is how severely brain-injured patients who regain consciousness can also regain their personhood. The case of patients with locked-in syndrome is illustrative in this matter. Upon restoration of consciousness, patients with LIS find themselves in a state of profound demolition of their bodily functions. From the third-person perspective, it can be (...) expected that LIS patients might experience a differential personal identity and may lose their status as persons. However, from the patients’ perspective, it is uncontested that they retain their personal identity and that they consider themselves to be persons. We here include results from a survey with patients with LIS aimed at identifying the primary expectations of patients for their care by non-medical professionals. Based on these first-hand reports, we argue that personhood in LIS is progressively regained as the widening circle of others recognizes them as persons. (shrink)

Defined as the ability to understand and share others' feelings and suffering, empathy seems to come naturally to mind when we consider Simone Weil's life and works. If this concept doesn't explicitly appear in her writings, "pity", "sympathy" and "compassion" are pervasive: the purpose of this paper is to demonstrate how these notions converge on the contemporary understanding of "empathy". Since the turn of the century, this concept has known such a development that it has become difficult to clearly identify (...) its object, and to appreciate its ethical value. To study Simone Weil's works from the angle of empathy offers both a new approach of the concept, and a very relevant point of view to put in light the great continuity between all the fields of the philosopher's thought. Our main hypothesis is that the weilian theory of empathy is based on the idea of "transposition", a process that allows someone to transport himself into another person, and from the natural to the supernatural dimension. It is in this last dimension that Simone Weil can found intersubjectivity, and solve the ethical problem of empathy: the right distance between the Self and the Other. (shrink)

The excavations carried out beside the north rampart of the lower town of Amathus have revealed the existence of a large archaic deposit, most probably originating from a destruction of the palace on the acropolis. This is the first part of a series of articles devoted to the material from this deposit. It deals with the context of its discovery, and considers the circular structure, which requires careful attention, filled by this material.

La spettacolare invasione della parola “biodiversità” nelle sfere scientifiche e politiche così come nei media ha suggerito la possibile nascita di un nuovo campo d’indagine scientifica. Tuttavia, la diversità del mondo vivente è stata l’oggetto di studio della storia naturale sin dai primordi. Gli ecologi non hanno aspettato la pubblicazione di “Biodiversity” di Wilson e Peter, nel 1988, per prendere in esame la diversità delle specie all’interno degli ecosistemi e per occuparsi di questioni fondamentali come i processi di diversificazione e (...) il significato funzionale della diversità specifica. L’analisi degli articoli pubblicati a partire dagli anni Quaranta, fino al 1988, ci permette di comprendere di quali argomenti, relativi al tema della diversità, si sono occupati gli ecologi, e come le intuizioni, gli approcci teorici e la ricerca empirica abbiano interagito. La domanda che si pone è: l’invenzione della biodiversità ha promosso la ricerca? Uno sguardo alle pubblicazioni post-1988 consente di suggerire una risposta. (shrink)

Personhood is ascribed on others, such that someone who is recognized to be a person is bestowed with certain civil rights and the right to decision making. A rising question is how severely brain-injured patients who regain consciousness can also regain their personhood. The case of patients with locked-in syndrome is illustrative in this matter. Upon restoration of consciousness, patients with LIS find themselves in a state of profound demolition of their bodily functions. From the third-person perspective, it can be (...) expected that LIS patients might experience a differential personal identity and may lose their status as persons. However, from the patients’ perspective, it is uncontested that they retain their personal identity and that they consider themselves to be persons. We here include results from a survey with patients with LIS aimed at identifying the primary expectations of patients for their care by non-medical professionals. Based on these first-hand reports, we argue that personhood in LIS is progressively regained as the widening circle of others recognizes them as persons. (shrink)

Blandine Kriegel, at one time a collaborator with Michel Foucault, is one of France's foremost political theorists. This translation of her celebrated work L'Etat et les esclaves makes available for English-speaking readers her impassioned defense of the state. Published in France in 1979 and republished in 1989, this work challenged not only the anti-statism of the 1960s but also generations of romanticism in politics that, in Kriegel's view, inadvertently threatened the cause of liberty by refusing to distinguish between the (...) despotic and the lawful state. In a work that addresses the urgent concerns of Europe and the contemporary world as a whole, Kriegel examines the background of modern liberal democracy in the late seventeenth and eighteenth centuries and argues cogently for the future of constitutional social-democracy. She maintains, among other positions, that European liberal democracies would have been impossible without the political basis provided by the lawful state first developed by monarchies. She also shows that early modern centralized states became liberal insofar as they developed a centralized legal system, rather than a centralized administration. In developing these ideas, she presents a picture of the state as a major force for human liberty. (shrink)

La campagne de fouille 2014 au palais d’Amathonte (fig. 1) a eu lieu du 16 juin au 11 juillet 2014. Les objectifs de cette campagne étaient triples : finir la fouille, commencée en 2011, de la zone 26‑27 ; en vue de la publication finale, réaliser un certain nombre de sondages stratigraphiques pour établir un phasage des différents sols et structures architecturales mis au jour ; améliorer la présentation générale du site en rectifiant plusieurs arrêts de fouille érodés. Fig. 1 (...) – Zones fouill... (shrink)

Pourquoi tant d'énergie à masquer les origines de notre Etat moderne? Que doit-il donc au droit romain et à la féodalité? Est-il vraiment né de la guerre comme on le répète depuis des années?