Pleiotropically acting eukaryotic corepressors such as retinoblastoma and SIN3 have been found to physically interact with many widely expressed “housekeeping” genes. Evidence suggests that their roles at these loci are not to provide binary on/off switches, as is observed at many highly cell‐type specific genes, but rather to serve as governors, directly modulating expression within certain bounds, while not shutting down gene expression. This sort of regulation is challenging to study, as the differential expression levels can be small. We hypothesize (...) that depending on context, corepressors mediate “soft repression,” attenuating expression in a less dramatic but physiologically appropriate manner. Emerging data indicate that such regulation is a pervasive characteristic of most eukaryotic systems, and may reflect the mechanistic differences between repressor action at promoter and enhancer locations. Soft repression may represent an essential component of the cybernetic systems underlying metabolic adaptations, enabling modest but critical adjustments on a continual basis. (shrink)

This paper seeks to highlight the East‐West asymmetry in philosophical exchanges. It draws attention to the absence of Eastern thought in the curriculum of philosophy in the West and suggests that cliches and stereotypes about cultures in general and thought‐traditions in particular are perpetuated in this manner. The aim of the paper is to encourage ‘cross‐cultural conversation’ among philosophers. A critical review of the project of ‘comparative philosophy’ is made to disclose the fact that despite the difficulties of such an (...) endeavor, it is an attempt to bring thought‐traditions together and is thereby useful for promoting intercultural understanding. (shrink)

Objective: To explore the relationship between the presentation of suffering and support for euthanasia in the British news media.Method: Data was retrieved by searching the British newspaper database LexisNexis from 1996 to 2000. Twenty-nine articles covering three cases of family assisted suicide were found. Presentations of suffering were analysed employing Heidegger’s distinction between technological ordering and poetic revealing.Findings: With few exceptions, the press constructed the complex terrain of FAS as an orderly or orderable performance. This was enabled by containing the (...) contradictions of FAS through a number of journalistic strategies: treating degenerative dying as an aberrant condition, smoothing over botched attempts, locating the object of ethical evaluation in persons, not contexts, abbreviating the decision making process, constructing community consensus and marginalising opposing views.Conclusion: The findings of this study support the view that news reporting of FAS is not neutral or inconsequential. In particular, those reports presenting FAS as an orderly, rational performance were biased in favor of technical solutions by way of the legalisation of euthanasia and/or the involvement of medical professionals. In contrast, while news reports sensitive to contradiction did not necessarily oppose euthanasia, they were less inclined to overtly support technical solutions, recognising the importance of a trial to address the complexity of FAS. (shrink)

The article explores Alexis de Tocqueville’s explication of democracy as ‘civil religion’ or the new sacred of modern times. In Democracy in America, Tocqueville analyzed democracy as a political system as well as a moral value. The article begins with Tocqueville’s analysis of the religious roots of American democracy. Dissociated from the affairs of the state through the principle of ‘disestablishment’, religion became secure in civil society, whereas the concept of democracy became inviolable and ‘set apart’ as sacred. He noted (...) that the power of the majority acquires an inviolable character in democracy that had the potential to turn against the very principles that it upholds. In the Indian context, the debate around a uniform civil code is one such issue that captures this predicament. Working out a roadmap for Indian pluralism signposted with a constitutional commitment to equality, liberty and fraternity has proved to be a task fraught with moral and political complexities, if not impasse. The article argues that Tocqueville’s discovery of the role of religion in civil society, his mistrust of democratic majoritarianism and his emphasis on understanding the ‘practice’ of democracy have something to offer to the polarized UCC debate in India. (shrink)

This book analyses the many facets-psychological, epistemological, metaphysical-of the repeated philosophical adventures over centuries to explore and explain the indubitability of I-consciousness. While the major focus is on the Upanisadic and the Buddhist traditions, this volume also examines Western philosophical traditions in a cross-cultural philosophical context.

This article seeks to delineate some of the fundamental philosophical traits that are special characteristics of the Indian cultural soil. Tracing these from the Vedic period, it is shown that this heritage is still alive and gives a distinctive flavor to the science–religion dialogue in the Indian context. The prevalent attitude is not to view science and religion as antagonistic, but rather as forces that together could create a world where the persistent epistemological and ethical problems can get resolved to (...) the benefit of humanity. In Indian thought rationality and spirituality are not viewed as opposed categories. The notion of “evidence” has played a crucial role in all enquiries for legitimizing the sources of knowledge and the criteria by which any claim to knowledge can be tested. References to investigations pertaining to such areas as cosmology, ecology, ethics, study of consciousness, and so on are made in order to bring out their relevance for science–religion dialogue today. (shrink)

In this paper, I discuss the ethical underpinnings to the anthropological analysis of age and reproductive decline in the ‘management’ of infertility, by suggesting that assisted reproductive technologies ‘use’ age and reproductive decline to further endanger women’s bodies by subjecting it to disaggregation into parts that do not belong to them anymore. Here, the category of age becomes a malleable concept to manipulate women seeking fertility management. In ethnographic findings from two Indian ART clinics, amongst women aged between 20 and (...) 35 years visiting an IVF/art clinic in Hyderabad city in South India, and women above 50 years of age visiting an IVF/art clinic in Hisar in North India—reproductive bodies are similarly disaggregated. In case of younger women, the treatment is fixated on rescuing eggs that may be in ‘decline’, and in case of older women, the aim is to engineer a viable pregnancy. Thus, the constant focus on eggs and wombs in infertility treatment creates a body that is not only not whole but also completely without agency. Age becomes a category that has rhetorical value to ‘push’ or persuade women into particular forms of fertility management through infertility medicine. I undertake a problematization of the egg and the uterus through the identification of the recurring motif of the menstrual cycle within IVF treatment to suggest that bodily holism is not part of ART discourse that unethically thrives on promoting technological intrusions to promote its use and normalization. (shrink)

Anthology of articles on the integral philosophy of Sri Aurobindo Ghose, 1872-1950, modern Indian philosopher.

This volume comprises a number of letters between author Anindita Niyogi Balslev and philosopher Richard Rorty. The letters explore ways to generate a creative and critical crosscultural discourse not only by challenging stereotypes about cultures and subcultures in general and traditions of thought in particular, but by being careful not to abolish the common ground on which stereotypes can be addressed.

Since its first publication, A Study of Time in Indian Philosophy has been acclaimed as having successfully shown •the simple falsityê of such clich_s that the Indian view of time is •cyclicê or that it is exclusively •illusoryê. Given the variety of views discussed in this work, it is evident that the theme of time is intimately related to such basic concepts as being and becoming, change and causality, creation and annihilation. It has been therefore, observed that this book makes (...) an excellent introduction to the heart of Indian thought. Based on Sanskrit source material, this book is a unique attempt to presenting a comprehensive review of the widely divergent views about time in Indian thought. Clearly written, it succeeds in setting out the issues of discussion pointedly and cogently. Since the concept of time intervenes with such major concepts as that of causality, being and non-being etc., this book also –serves as a general introduction to the classic heart of Indian Philosophy.” The author –has demonstrated a rare ability to translate technical doctrines from one tradition of thought into the language of another”, and thus has made it possible- for all those who are concerned with the question of time but do not have access in the Indian conceptual world to appreciate the contributions of Indian thought with regard to this complex question. Noteworthy is the fact that this book is the first attempt which –successfully exposes the simple falsity” of such cliches as that the Indian view of time is •cyclic as opposed to the Judaeo-Christian understanding of linear time. A Study of Time in Indian Philosophy, therefore, renders a valuable service to all those who are concerned with cross-cultural and inter religious exchange. (shrink)

would suspect him of murdering them and would not spare him. So he too killed himself. Gods were very much disturbed by this sad incident and realized the ...

Abstract. Does reflection on the phenomenon of I-consciousness only lead to a reaffirmation that what is closest to us is furthest from our understanding? This enigmatic theme has been addressed in Indian and Western philosophical traditions from various perspectives, with different intents. Why do philosophers disagree while accounting for this phenomenon, although they seem to generally accept the indubitability of I-consciousness? The discussion focuses on the kind of philosophical issues that are raised and how differently these are dealt with. In (...) the process, the reader will be acquainted with various types of analyses from the history of Indian thought, where one comes across many renditions of contrasting views about “Self” as a well as of “No-Self.” The focus is in how these enquiries gradually assume not only epistemological and metaphysical but also important ethico-religious dimensions. Beginning with naturalistic interpretations in the Indian context, it will be outlined why mainstream traditions reject naturalism as an explanatory model. (shrink)

. This paper outlines some major ideas concerning cosmogony and cosmogony and cosmology that pervade the Hindu conceptual world. The basic source for this discussion is the philosophical literature of some of the principal schools of Hindu thought, such as VaiVaiśika, Sānkhya, and Advaita Vedānta, focusing on the themes of cosmology, time, and soteriology. The core of Hindu philosophical thinking regarding these issues is traced back to the Rk Vedic cosmogonical speculations, analyzed, and contrasted with the “views of the opponent.” (...) The relevance of the Hindu worldview for overcoming the conflict between science and religion is pointed out. (shrink)

This book proposes a radical shift in the way the world thinks about itself by highlighting the significance of cross-cultural conversations. Moving beyond conventional boundaries such as nation-state and identity, it examines the language in which histories are written; analyses how scientific technology is changing the idea of identity, and highlights a larger identity across nationality, race, religion, gender, ethnicity and class. Cross-Cultural Conversation reviews and articulates the interconnectedness of people by 'crossing' the 'hard' boundaries of religious, national, racial, ethnic, (...) gender and other forms of social and local identities. It asks for a concerted effort to engaging each other in open conversational forums on a range of global issues, altering our attitudes towards self and the other, and unlearning prejudices that perpetuate divisive identities. Intended as a tool for conflict resolution, communication and forging human interrelationships, cross-cultural conversation emphasizes the crucial role of individuals, public institutions and civil society, and encourages partnership in various domains of social exchanges to enable us to imagine a new phase of human civilization. The book explores themes such as cultural diversity, political actions, solidarity-in-diversity, clash of social identities, tensions between nationalism and globalism, ethico-religious challenges, the quest for global peace and authentic meeting of world religions, the evolving connection between science and religion, and attitudinal differences between Western and Indian scientists toward religion as also on key philosophical ideas that have permeated the Indian cultural soil. unication and forging human interrelationships, cross-cultural conversation emphasizes the crucial role of individuals, public institutions and civil society, and encourages partnership in various domains of social exchanges to enable us to imagine a new phase of human civilization. The book explores themes such as cultural diversity, political actions, solidarity-in-diversity, clash of social identities, tensions between nationalism and globalism, ethico-religious challenges, the quest for global peace and authentic meeting of world religions, the evolving connection between science and religion, and attitudinal differences between Western and Indian scientists toward religion as also on key philosophical ideas that have permeated the Indian cultural soil. (shrink)

This book delves deep into the Social Construction of Theory, comparative epistemology and intellectual history to stress the interrelationship between diverse cultures during the colonial period and bring forth convincing evidence of how the 19th century was shaped. It approaches an interesting relation between the linguistic studies of 19th century’s scientific world and subsequent widespread acceptance of the empirically weak theory of the Aryan invasion. To show entangled history in a globalized world, the book draws on the Aryan Invasion Theory (...) to highlight how different socio-religious parties commonly shape a new theory. It also explores how research is affected by the so-called social construction of theory and comparative epistemology, and deals with scholarly advancement and its relation with contemporary socio-political demands. The most significant conclusion of the book is that academic studies are prone to comparative epistemology, even under the strict scrutiny of the so-called scientific methods. (shrink)

Acquiring expertise in a task is often thought of as an automatic process that follows inevitably with practice according to the log‐log law (aka: power law) of learning. However, as Ericsson, Chase, and Faloon (1980) showed, this is not true for digit‐span experts and, as we show, it is certainly not true for Tetris players at any level of expertise. Although some people may simply “twitch” faster than others, the limit to Tetris expertise is not raw keypress time but the (...) techniques acquired by players that allow them to use the tools provided by the hardware and software to compensate for the game's relentlessly increasing drop speed. Unfortunately, these increases in drop speed between Tetris levels make performance plateaus very short and quickly followed by game death. Hence, a player's success at discovering, exploring, and practicing new techniques for the tasks of board preparation, board maintenance, optimal placement discovery, zoid rotation, lateral movement of zoids, and other tasks important to expertise in Tetris is limited. In this paper, we analyze data collected from 492 Tetris players to reveal the challenges they confronted while constructing expertise via the discovery of new techniques for gameplay at increasingly difficult levels of Tetris. (shrink)

Rough Sets were introduced by Z. Pawlak in the year 1982 with the intention to address knowledge representation and data processing from the angle of computation and decision making. The main idea...

This article contains the principal ideas that I presented in four different sessions at the IRAS 2022 conference, on the theme “‘We' and ‘They’: Cross-Cultural Conversation on Identity.” Focusing on the central topic, the article begins with (i) the contents of my opening lecture; followed by (ii) a broad outline of the concerns discussed in my book, Cross-Cultural Conversation: A New Way of Learning, intertwined with glimpses of the intellectual journey that led me to CCC, delivered in the Book-discussion session; (...) (iii) a summary of the main ideas about the importance of meeting of religions today, which formed the background for the CCC Panel discussion on religion, where I was in conversation with spokespersons of five world religions; and (iv) my comments on how science–religion dialogue can help promote a sense for human solidarity by combining knowledge with wisdom, in the concluding session. (shrink)

Despite increasing pressure to deal with climate change, firms have been slow to respond with effective action. This article presents a multi-level framework for a better understanding of why many firms are failing to reduce their absolute greenhouse gas emissions, which contribute to climate change. The concepts of short-termism and uncertainty avoidance from research in psychology, sociology, and organization theory can explain the phenomenon of organizational inaction on climate change. Antecedents related to short-termism and uncertainty avoidance reinforce one another at (...) three levels—individual, organizational, and institutional—and result in organizational inaction on climate change. The article also discusses the implications of this multi-level framework for research on corporate sustainability. (shrink)

In this article I provide a critical perspective on governing the global corporation. While the papers in the 2009 special issue of Business Ethics Quarterly explore the political role of corporations I argue that they lack a sophisticated analysis of power acrossinstitutional and actor networks. The argument that corporate engagement with deliberative democracy can enhance the legitimacy of corporations does not take into account the effects of institutional, material and discursive forms of power that determine legitimacycriteria. As a result corporate (...) versions of citizenship mediate versions of social responsibility and morality, which are reflected in the institutional and political economic norms that are produced by this power/knowledge. In order to overcome the limits of corporate social responsibility there is a need to develop more democratic forms of global governance of corporations. A radical revisioning of democratic governance would also need to overcome the limits posed by sovereignty and would require new forms of multi-actor and multi-level translocal governance arrangements in an attempt to create forms of power that are more compatible with the principles of economic democracy. (shrink)

A hypertext learner navigates with a instinctive feeling for a knowledge. The learner does not know her queries, although she has a feeling for them. A learner’s navigation appears as complete upon the emergence of an aesthetic pleasure, called rasa. The order of arrival or the associational logic and even the temporal order are not relevant to this emergence. The completeness of aesthetics is important. The learner does not look for the intention of the writer, neither does she look for (...) significance. Lexia has a suggestive power and she is suggested in the arrival of aesthetics. Hypertext learning does not depend on communication. The learner in her pleasure transgresses the bounds of space-time to be in communion with several writers/learners. Hypertext learning does not appear to be fundamentally different from the analog learning; however, in performance, as in navigation, the learner assumes a mental state that helps her in her emergence into aesthetic bliss, of an arrival to the completed lexial navigation. This completeness is owing to aesthetics and is not owing to either the semantics or the query-fulfilling qualities. (shrink)

Contemporary democracy has given primacy to thought. Building up institutions on thought and reasoned discourse excludes out human actions derived not from thought that one thinks. Ordinary life is visited by emotion and passion. Such actions of unknown origin are captured best in the drama. Indian theory and practice of drama and the poetics offer communion between the performer and the viewer. Blissful relish of the actions and the dialogues lift up the banal actions from the ordinary to a state (...) beyond simple event. Relishing thus resides in cognition. Drama in theory and in its practice thus offers foundation to institutions that could embrace independent actions as well. In relish there is cognition and reasoning alone cannot lay claim. Folk life and folk actions thus could be emancipatory. (shrink)

This paper addresses questions of women’s autonomy in India and analyses its location within the legal discourse. The women’s movement has primarily tried to analyse questions of women’s autonomy through exploring women’s position in law. Among other indicators, women’s position in society is often analysed through marriage, divorce and property acts. This paper analyses the evolution of these acts and critiques whether they have led to women’s autonomy or merely subsumed questions of autonomy resulting in further marginalization of women in (...) the polity. The paper begins with the assumption that locations matter and that laws affect different women differently, particularly in the context of India where civil law is constantly pitted against personal and customary law. To understand the situation of women in India, therefore, an understanding of the evolution of laws seems necessary, because laws are considered to be primary markers of autonomy. (shrink)

Previous research with adults suggests that a catalog of minimally counterintuitive concepts, which underlies supernatural or religious concepts, may constitute a cognitive optimum and is therefore cognitively encoded and culturally transmitted more successfully than either entirely intuitive concepts or maximally counterintuitive concepts. This study examines whether children's concept recall similarly is sensitive to the degree of conceptual counterintuitiveness (operationalized as a concept's number of ontological domain violations) for items presented in the context of a fictional narrative. Seven- to nine-year-old children (...) who listened to a story including both intuitive and counterintuitive concepts recalled the counterintuitive concepts containing one (Experiment 1) or two (Experiment 2), but not three (Experiment 3), violations of intuitive ontological expectations significantly more and in greater detail than the intuitive concepts, both immediately after hearing the story and 1 week later. We conclude that one or two violations of expectation may be a cognitive optimum for children: They are more inferentially rich and therefore more memorable, whereas three or more violations diminish memorability for target concepts. These results suggest that the cognitive bias for minimally counterintuitive ideas is present and active early in human development, near the start of formal religious instruction. This finding supports a growing literature suggesting that diverse, early-emerging, evolved psychological biases predispose humans to hold and perform religious beliefs and practices whose primary form and content is not derived from arbitrary custom or the social environment alone. (shrink)

Research on moral psychology has frequently appealed to three, apparently consistent patterns: Males are more likely to engage in transgressions involving harm than females; educated people are likely to be more thorough in their moral deliberations because they have better resources for rationally navigating and evaluating complex information; political affiliations and religious ideologies are an important source of our moral principles. Here, we provide a test of how four factors ‐ gender, education, politics and religion ‐ affect intuitive moral judgments (...) in unfamiliar situations. Using a large-scale sample of participants who voluntarily logged on to the internet-based Moral Sense Test, we analyzed responses to 145 unique moral and conventional scenarios that varied widely in content. Although each demographic or cultural factor sometimes yielded a statistically significant difference in the predicted direction, these differences were consistently associated with extremely small effect sizes. We conclude that gender, education, politics and religion are likely to be relatively insignificant for moral judgments of unfamiliar scenarios. We discuss these results in light of current debates concerning the mechanisms underlying our moral judgments and, especially, the idea that we share a universal moral sense that constrains the range of cross-cultural variation. (shrink)

Acquiring expertise in a task is often thought of as an automatic process that follows inevitably with practice according to the log‐log law (aka: power law) of learning. However, as Ericsson, Chase, and Faloon (1980) showed, this is not true for digit‐span experts and, as we show, it is certainly not true for Tetris players at any level of expertise. Although some people may simply “twitch” faster than others, the limit to Tetris expertise is not raw keypress time but the (...) techniques acquired by players that allow them to use the tools provided by the hardware and software to compensate for the game's relentlessly increasing drop speed. Unfortunately, these increases in drop speed between Tetris levels make performance plateaus very short and quickly followed by game death. Hence, a player's success at discovering, exploring, and practicing new techniques for the tasks of board preparation, board maintenance, optimal placement discovery, zoid rotation, lateral movement of zoids, and other tasks important to expertise in Tetris is limited. In this paper, we analyze data collected from 492 Tetris players to reveal the challenges they confronted while constructing expertise via the discovery of new techniques for gameplay at increasingly difficult levels of Tetris. (shrink)

Rather than a natural product, a computational analysis leads us to characterize déjà vu as a failure of memory retrieval, linked to the activation in neocortex of familiar items from a compositional memory in the absence of hippocampal input, and to a misappropriation by the self of what is of others.

AbstractIn this paper I provide a decolonial critique of received knowledge about deliberative democracy. Legacies of colonialism have generally been overlooked in theories of democracy. These omissions challenge several key assumptions of deliberative democracy. I argue that deliberative democracy does not travel well outside Western sites and its key assumptions begin to unravel in the ‘developing’ regions of the world. The context for a decolonial critique of deliberative democracy is the ongoing violent conflicts over resource extraction in the former colonies (...) of Africa, Asia and Latin America. I argue that deliberative democracy cannot take into account the needs of marginalized stakeholders who are defending their lands and livelihoods. The paper contributes to the literature by (1) offering a critique of hegemonic models of democracy that cannot address issues of inequality and colonial difference and (2) offering possibilities to imagine counterhegemonic alternatives for a democratization of democracy from below. (shrink)

Through a philosophical engagement with “Arju” (communal dormitories for children/adolescents among the Ao tribe, India), we develop a distinct conceptualization of it as “caring space, in-between”. In its various ontological, epistemological, and ethical dimensions, Arju becomes a space for mothering of Ao children and of caring for the tribe at large. It provides a basis for developing a notion of “caring space” within a philosophy of care. Finally, while theorizing its “in-between” character, we argue that Arju resists mapping onto dominant (...) Western spatial binaries such as private/public, home/world, etc. This essay is not only an articulation of a non-dominant group’s philosophy of “mothering” and “care”, but also aims to create an alternative theoretical space from which to engage with the dominantly Western feminist philosophies of care. (shrink)

The collapse of the wavefunction is arguably the least understood process in quantum mechanics. A plethora of ideas—macro-micro divide, many worlds and even consciousness—have been put forth to resolve the issue. Contrary to the standard Copenhagen interpretation, objective collapse models modify the Schrödinger equation with nonlinear and stochastic terms in order to explain the collapse of the wavefunction. In this paper we propose a collapse model in which a particle’s wavefunction has a possibility of collapsing when it interacts with macroscopic (...) objects, without the intervention of a conscious observer. We propose four possible conditions of collapse of the wavefunction and make testable predictions which differ from standard quantum mechanics. (shrink)

Research on human-animal interaction has skyrocketed in the last decade. Rapid urbanization has led scientists to investigate its impact on several species living in the vicinity of humans. Domesticated dogs (Canis lupus familiaris) are one such species that interact with humans and are also called man’s best friend. However, when it comes to the free-ranging population of dogs, interactions become quite complicated. Unfortunately, studies regarding free-ranging dog-human interactions are limited even though the majority of the world’s dog population is free-ranging. (...) In this study, we observed twelve groups of free-ranging dogs in their natural habitat, the streets. We divided the study areas into two zones, namely – intermediate and high flux, based on human activity or movement. Six groups from each of the zones were observed mostly during daytime. We used social network analysis (SNA) to explore the dog-dog (intraspecific) and dog-human (interspecific) interactions. It was surprising to observe higher instances of interspecific interactions than the intraspecific ones, irrespective of the zones. Humans, in significantly higher occasions, initiated both positive and negative interactions in comparison to dogs. Our findings conclude that humans are a crucial part of the interaction network of Indian free-ranging dogs. (shrink)

differential from bottom to top, depth of fluid, and the coefficients of expansion, viscosity and thermal Bénard convection, is one of the more intensely conductivity of the fluid. Even though it is a simple studied dissipative systems, both theoretically and..

In this article, we examine the shifting roles played by non-state actors in governing areas of limited statehood. In particular, we focus on the emergence of voluntary grassroots organizations in Palestine and describe how regimes of international development aid transformed these organizations into professional nongovernmental organizations (NGOs) that created new forms of colonial control. Based on in-depth interviews with 145 NGO members and key stakeholders and a historical analysis of limited statehood in Palestine, we found that social relations became disembedded (...) from the local context and re-embedded in new relations with international donor organizations resulting in a depoliticized public sphere. NGOization of the economy also resulted in new forms of exclusion and inclusion as well as contestations between a new class of urban middle-class professionals working in NGOs and the older generation of activists who were involved in grassroots organizations. Our findings have implications for business and human rights and governance in areas of limited statehood, in particular how private actors such as NGOs are able to exercise power in the economy. (shrink)