The question of whether corporate social responsibility (CSR) has a positive impact on firm value has been almost exclusively analysed from the perspective of the stock market. We have therefore investigated the relationship between the valuation of Euro corporate bonds and the standards of CSR of mainly European companies for the first time in this article. Generally, the debt market exhibits a considerable weight for corporate finance, for which reason creditors should basically play a significant role in the transmission of (...) CSR into the valuation of financial instruments. Given that socially responsible firms are often regarded as economically more successful and less risky, they should have lower risk premia. The results of the empirical analysis, however, reveal that based on an extensive data panel the risk premium for socially responsible firms – according to the classification by SAM Group – was ceterius paribus higher than for non-socially responsible companies. However, only one case of the models investigated was weakly significant. Thus, largely the relationship has to be classified as marginal; so CSR has apparently not yet been incorporated into the pricing of corporate bonds. (shrink)

Science is a matter of facts, not only of objects. (1) This applies to the theory itself and to experimental research as well. Experiments do not confirm hypotheses but are themselves the scientific result because they demonstrate security of action. (2) Thus not only experimental action is to be evaluated ethically but science itself. The development of atomic weapons has shown that there is no segregation between ,,basic research' and technical application. (3) Ethical criteria for the evaluation of scientific action (...) in laboratory research and beyond are love, adequacy, and embedding (conservation knowledge). (4) A moral order of scientific action could be developed along these orientations in justice and freedom if they were granted to the connatural world as they are in human society. German Die moderne Naturwissenschaft handelt von Tat-Sachen, nicht nur von den Sachen. (1) Handlungsförmig ist bereits der theoretische Entwurf, nicht erst das Experiment. Das letztere dient in der Regel nicht der Bestätigung von Hypothesen, sondern ist selbst das wissenschaftliche Ergebnis, denn es zeigt die Sicherheit im Handeln. (2) Das ethisch zu bewertende Handeln umfaßt also über die Laborforschung hinaus die ganze Wissenschaft. Die Entwicklung der Atombombe hat die grundsätzliche Untrennbarkeit von ,,Grundlagenforschung' und technischer Anwendung bewiesen. (3) Ethische Kriterien für das Erkenntnishandeln in der Laborforschung und darüber hinaus sind Liebe, Angemessenheit und Einbettung (Erhaltungswissen). (4) Eine sittliche Ordnung dieses Handelns kann sich nach den drei Kriterien in Gerechtigkeit und Freiheit ergeben, wenn diese über die menschlichen Gesellschaften hinaus auch der natürlichen Mitwelt zuteil werden sollen. (shrink)

Nanotechnology is an important platform technology which will add new features like improved biocompatibility, smaller size, and more sophisticated electronics to neuro-implants improving their therapeutic potential. Especially in view of possible advantages for patients, research and development of nanotechnologically improved neuro implants is a moral obligation. However, the development of brain implants by itself touches many ethical, social and legal issues, which also apply in a specific way to devices enabled or improved by nanotechnology. For researchers developing nanotechnology such issues (...) are rather distant from their daily work in the lab, but as soon as they use their materials or devices in medical applications such as therapy of brain diseases they have to be aware of and deal with them. This paper is intended to raise sensitivity for the ethical, legal and social aspects (ELSA) involved in applying nanotechnology in brain implants or other devices by highlighting the short term problems of testing and clinical trials within the existing regulatory frameworks (A), the short and medium-term questions of risks in the application of the devices (B) and the long-term perspectives related to problems of enhancement (C). To identify and address such issues properly nanotechnologists should involve ethical, legal and social experts and regulatory bodies in their research as early as possible. This will help to remove pressure from regulatory bodies, to settle public concern and to prevent non-acceptable developments for the benefit of the patients. (shrink)

Nanomedicine offers remarkable options for new therapeutic avenues. As methods in nanomedicine advance, ethical questions conjunctly arise. Nanomedicine is an exceptional niche in several aspects as it reflects risks and uncertainties not encountered in other areas of medical research or practice. Nanomedicine partially overlaps, partially interlocks and partially exceeds other medical disciplines. Some interpreters agree that advances in nanotechnology may pose varied ethical challenges, whilst others argue that these challenges are not new and that nanotechnology basically echoes recurrent bioethical dilemmas. (...) The purpose of this article is to discuss some of the ethical issues related to nanomedicine and to reflect on the question whether nanomedicine generates ethical challenges of new and unique nature. Such a determination should have implications on regulatory processes and professional conducts and protocols in the future. (shrink)

BackgroundTo prevent the planet from catastrophic global warming a reduction of greenhouse gas emissions to net zero is required. Thus, divestment from fossil fuels must be a strategic interest for health insurers. The aim of this study was to analyse the implementation of environmental, social and governance criteria in German private health insurers’ investments.MethodsIn 2019 a survey about ESG strategies was sent to German private health insurance companies. The survey evaluated investment strategies and thresholds for the exclusion of sectors and (...) business practices, as well as company strategies for sustainable business development.FindingsGiven their business reports, German private health insurers manage assets of more than €350 billion. 11 of 40 insurance companies provided quantitative data, 10 refused to answer. According to quantitative data, €66 billion of assets is managed according to any ESG criteria; this equals an average of 76% of each company’s bonds. None of these insurers excluded the production and sale of fossil fuels. All excluded coal mining but only at high thresholds. For €226 billion, no data were provided.InterpretationThe findings are in contrast to the expected intrinsic economic interest of the insurers to stop global warming and improve public health. The majority of assets are managed in a highly problematic manner, especially the absence of capital allocated in fields contrary to medical ethics cannot be presumed. Lack of transparency is a major problem that limits clients in choosing the insurer who has the most advanced ESG criteria. (shrink)

Abilities such as peripheral reaction are of special importance in soccer. Whether these abilities can be improved by sport-specific on-field interventions remains unclear. The aim of the present controlled trial was to investigate the effect of a soccer-specific perceptual-cognitive on-field training on peripheral reaction of highly talented soccer players aged 12 to 13 years. N = 38 male elite athletes from young talent centers were allocated to an intervention (n = 19) and a control group (n = 19). Computer-based peripheral (...) perception tests were conducted pre- and post-intervention. Combining a sport-specific and a juggling task, the intervention was performed once a week (8 weeks, 20 min. per week) in addition to team training. The control group exclusively underwent usual team training. Analyzes show significant differences between the two groups for Peripheral Reaction Time, with significant improvements for the intervention group and none for the control group. Furthermore, results indicate that improvements in peripheral reaction might be due to changes in the reaction time of right-footed players. Future studies should be conducted to clarify the effect of sport-specific on-field training approaches on peripheral reaction time. These analyzes should consider the influence of lateralization on effectivity of perceptual-cognitive on-field training approaches. (shrink)

Proceedings of a conference held Sept. 2010 in Jena, Germany.

Meine Untersuchung gliedert sich in folgende Abschnitte: In einer Art Vorspiel wird anhand einiger Beispiele daran erinnert, wie Fichte selbst zum Gegenstand einer politischen Historiographie geworden ist, die dazu neigt, sich über die hochkomplexe interne Struktur der Theorie hinwegzusetzen. In einem zweiten Abschnitt wird Fichtes Geschichtsphilosophie umrissen. Ein dritter Abschnitt geht in den Texten zur Französischen Revolution der Frage nach, welcher Sinn dort eigentlich der Historiographie zugeschrieben wird. Und im vierten Abschnitt wird die gleiche Frage mit Blick auf das spätere (...) Werk, insbesondere die »Grundzüge«, traktiert. (shrink)

Meine Untersuchung gliedert sich in folgende Abschnitte: In einer Art Vorspiel wird anhand einiger Beispiele daran erinnert, wie Fichte selbst zum Gegenstand einer politischen Historiographie geworden ist, die dazu neigt, sich über die hochkomplexe interne Struktur der Theorie hinwegzusetzen. In einem zweiten Abschnitt wird Fichtes Geschichtsphilosophie umrissen. Ein dritter Abschnitt geht in den Texten zur Französischen Revolution der Frage nach, welcher Sinn dort eigentlich der Historiographie zugeschrieben wird. Und im vierten Abschnitt wird die gleiche Frage mit Blick auf das spätere (...) Werk, insbesondere die »Grundzüge«, traktiert. (shrink)

English translation by Kneller and Losonsky of Klaus Reich, Die Vollständigkeit der Kantischen Urteilstafel -/- "This classic of Kant scholarship, whose first edition appeared in 1932, deals with one of the most controversial and difficult topics in the Critique of Pure Reason: Kant's table of judgments and their connection to the table of categories. Kant's attempt to derive the latter from the former is called the "Metaphysical Deduction," and it paves the way for the Transcendental Deduction that is universally (...) recognized as the heart of the Critique." "Many commentators have passed over the Metaphysical Deduction in silence, as if embarrassed by Kant's fatuity, and his critics are almost unanimous in finding its premise ungrounded, its argument incorrect, and its conclusion false. At the heart of the failure of the Metaphysical Deduction, it is alleged, is Kant's inability to justify the table of the forms of judgment. Critics argue that Kant simply took these forms of judgment from the logic textbooks of his day and doctored them so as to yield the required categories. Such objections were current even in Kant's time; they were repeated by Hegel, and are commonplaces of Kant criticism today." "This book is the fullest and most systematic evaluation ever made of the Metaphysical Deduction. Reich argues that its principal conclusion is correct even though Kant failed to establish it in the Metaphysical Deduction proper, and he defends the conclusion by using Kant material far removed from the text of the Metaphysical Deduction, notes by Kant that only became available in the 1920's and that remain even now untranslated into English. With the publication of this translation for English-speaking Kant scholars, a neglected and impugned part of the Critique of Pure Reason can finally receive the attention it deserves."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)

Der Band "Idealismus und Romantik in Jena" nimmt die Jenaer Blütezeit zwischen 1794 und 1807 in den Blick und interpretiert sie als ein Neben- und Gegeneinander der beiden einflussreichsten Geistesströmungen um 1800. In Jena entstehen zwischen 1794 und 1807 zwei geistesgeschichtliche Strömungen von Weltgeltung: der Idealismus und die Romantik. Die rasante Entwicklung immer neuer Ideen ist durch eine beträchtliche Anzahl junger, kreativer Geister geprägt, die in fruchtbarem Austausch und gegenseitiger Kritik um ein neues, angemessenes Verständnis der Moderne ringen. Im Fokus (...) des Bandes stehen Fragen zu einzelnen Autoren genauso wie zum Verhältnis beider Strömungen zueinander. The volume Idealism and Romanticism in Jena focuses on the period between 1794 and 1807 in which creative and original minds developed new ideas for understanding the modern world. The contributions examine the relationship between German Idealism and Early Romanticism: What distinguishes/combines Idealism and Romanticism? What common aspects, synergies and goals arise? And what does the opposition between the two movements means for the question of modernity? (shrink)

Die Begriffe Körper und Gesundheit sind (nicht erst) seit dem sogenannten body-, corporeal- oder somatic-turn Gegenstand sehr unterschiedlicher Disziplinen und Perspektiven: Die Komplexität der Zusammenhänge, Verschränkungen, Bedingungen des Gegenstandspaares Körper-Gesundheit bis hin zur Identifikation macht es erforderlich, multidisziplinär und multiperspektivisch vorzugehen. In diesem Band sind unterschiedliche Disziplinen und Perspektiven versammelt, die sich aus ihrer Fachgenese und wissenschaftlichen Position heraus mit Körper, Leib und Gesundheit beschäftigen, um v.a. Forschungsfelder zu erschließen und praxeologische Konsequenzen zu benennen.

Die Beiträge fokussieren drei prominente Anwendungsgebiete von Big Data: Wissenschaft, Gesundheitswesen und Finanzmärkte. Dabei ist der Zweck nicht derjenige, Lösungen für ethische Probleme vorzulegen, sondern zuallererst diejenigen Aspekte der Anwendung von Big-Data-Technologien zu identifizieren, durch die ethische Fragen aufgeworfen werden, und den Rahmen abzustecken für ethische und wissenschaftstheoretische Reflexion und Beurteilung.Hinsichtlich des Anwendungsfeldes Wissenschaft ist dabei vorrangig von Interesse, ob Big Data – wie des Öfteren propagiert wird – einen Paradigmenwechsel auslösen könnte, und welche Erklärungskraft und praktische Verlässlichkeit Ergebnissen zugesprochen (...) werden können, die durch Verfahren wie Data Mining, maschinelles Lernen usw. zustande kommen.Big-Data-Technologien in Gesundheitswesen und medizinischer Praxis verstärken den Widerstreit zwischen Entlastung und Entmündigung. Die Gestaltung der Mensch-Maschine-Interaktion wird zu einer Kernaufgabe. Rückt der Werkzeugcharakter der Technologien aus dem Blick, geraten wir in die Zwänge einer Macht, die den Patienten entindividualisiert und menschliche Interaktionsformen in der medizinischen Praxis infrage stellt. (shrink)

Human severe combined immune deficiency (SCID) is the most serious inherited immunological deficit. Recent work has revealed defects in the predominant pathway for double‐strand break repair called nonhomologous DNA end joining, or NHEJ. Progress in the biochemistry and genetics of NHEJ and of human SCID has proven to be synergistic between these two fields in a manner that covers the range from biochemical etiology to considerations about possible gene therapy for the B− SCID patients. BioEssays 25:1061–1070, 2003. © 2003 Wiley (...) Periodicals, Inc. (shrink)