While endorsing Gopnik's proposal that studies of the emergence and modification of scientific theories and studies of cognitive development in children are mutually illuminating, we offer a different picture of the beginning points of cognitive development from Gopnik's picture of "theories all the way down." Human infants are endowed with several distinct core systems of knowledge which are theory-like in some, but not all, important ways. The existence of these core systems of knowledge has implications for the joint research program (...) between philosophers and psychologists that Gopnik advocates and we endorse. A few lessons already gained from this program of research are sketched. (shrink)

Background Dynamic consent has been proposed as a process through which participants and patients can gain more control over how their data and samples, donated for biomedical research, are used, resulting in greater trust in researchers. It is also a way to respond to evolving data protection frameworks and new legislation. Others argue that the broad consent currently used in biobank research is ethically robust. Little empirical research with cohort study participants has been published. This research investigated the participants’ opinions (...) of adding a dynamic consent interface to their existing study. Methods Adult participants in the Extended Cohort for E-health, Environment and DNA longitudinal cohort study who are members of the EXCEED Public and Participant Engagement Group were recruited. Four focus groups were conducted and analysed for thematic content. Discussion topics were derived from a review of the current literature on dynamic consent. Results Participants were in favour of many aspects of a dynamic consent interface, such as being able to update their information, add additional data to their records and choose withdrawal options. They were supportive provided it was simple to use and not intrusive. Participants expressed a markedly high level of trust in the study and its investigators and were unanimously happy with their current participation. No strong support was found for adding a dynamic consent interface to EXCEED. Conclusions Trust in the study researchers was the strongest theme found. Openness and good data security were needed to retain their trust. While happy to discuss dynamic consent, participants were satisfied with the current study arrangements. There were indications that changing the study might unnecessarily disturb their trust. This raised the question of whether there are contexts where dynamic consent is more appropriate than others. This study was limited by the small number of participants who were committed to the study and biased towards it. More research is needed to fully understand the potential impact of adding a dynamic consent interface to an existing cohort study. (shrink)

This dissertation concerns the methodology Kant employs in the first two sections of the Groundwork of the Metaphysics of Morals (Groundwork I-II) with particular attention to how the execution of the method of analysis in these sections contributes to the establishment of moral metaphysics as a science. My thesis is that Kant had a detailed strategy for the Groundwork, that this strategy and Kant’s reasons for adopting it can be ascertained from the Critique of Pure Reason (first Critique) and his (...) lectures on logic, and that understanding this strategy gains us interpretive insight into Kant’s moral metaphysics. At the most general level of methodology, Kant says there are four steps for the establishment of any science: 1) make distinct the idea of the natural unity of its material 2) determine the special content of the science 3) articulate the systematic unity of the science 4) critique the science to determine its boundaries The first two of these steps are accomplished by the genetically scholastic method of analysis, paradigmatically the method whereby confused and obscure ideas are made clear and distinct, thereby logically perfecting them and transforming them into possible grounds of cognitive insight that are potentially complete and adequate to philosophical purposes. The analysis of Groundwork I is a paradigmatic analysis that makes distinct what is contained in common understanding, i.e. its Inhalt or intension, making distinct the higher partial concepts that together define the concept of morality. The analysis of Groundwork II is an employment more specifically of the method of logical division, which makes distinct what is contained under the concept, i.e. its Umfang, by which the extension or object of morality is determined. Part I introduces Kant’s conception of moral metaphysical science and why he took it to be in need of establishment, explains the general method for establishing science and the scholastic method of analysis by which its first two steps are to be accomplished, then provides an interpretation of Groundwork I as an execution of this method. Part II details Kant’s determination of the special content of moral science in Groundwork II in relation to the central problem for moral metaphysics – how synthetic a priori practical cognition is possible. (shrink)

We examined the effects of three different training conditions, all of which involve the motor system, on kindergarteners’ mental transformation skill. We focused on three main questions. First, we asked whether training that involves making a motor movement that is relevant to the mental transformation—either concretely through action or more abstractly through gestural movements that represent the action —resulted in greater gains than training using motor movements irrelevant to the mental transformation. We tested children prior to training, immediately after training, (...) and 1 week after training, and we found greater improvement in mental transformation skill in both the action and move-gesture training conditions than in the point-gesture condition, at both posttest and retest. Second, we asked whether the total gain made by retest differed depending on the abstractness of the movement-relevant training, and we found that it did not. Finally, we asked whether the time course of improvement differed for the two movement-relevant conditions, and we found that it did—gains in the action condition were realized immediately at posttest, with no further gains at retest; gains in the move-gesture condition were realized throughout, with comparable gains from pretest-to-posttest and from posttest-to-retest. Training that involves movement, whether concrete or abstract, can thus benefit children's mental transformation skill. However, the benefits unfold differently over time—the benefits of concrete training unfold immediately after training ; the benefits of more abstract training unfold in equal steps immediately after training and during the intervening week with no additional training. These findings have implications for the kinds of instruction that can best support spatial learning. (shrink)

The presence of the Tuskegee Syphilis Study was palpable at the June 16, 2005, Food and Drug Administration’s Advisory Committee meeting on BiDil, a heart medication from the pharmaceutical company NitroMed that sought approval as the first race-specific drug. So ubiquitous is the restless and unsettled spirit of Tuskegee that it continues to hover over the African American public and the biomedical research/health care provider communities more than three and a half decades after the actual study “died.” No one invoked (...) the word “Tuskegee” in that dimly lit meeting room as BiDil gained the Advisory Committee’s approval. Yet its power was exerted even when it was not named. The FDA Committee’s chairman, Cleveland Clinic cardiology chief Steven Nissen, acknowledged this after the committee met: “We were putting [Tuskegee]…to rest.”. (shrink)

Where research was once strictly confined to one laboratory or office, investigators now widely share and compare their plans, analyses, and results. With the advent of genomic knowledge, researchers are seeking to understand the genetics and genomics of complex human disease. They are combining their efforts into international consortia in order to take on problems that face individuals around the world, such as cancer and malaria — problems that are too large to solve by one country alone. These consortia bring (...) together diverse research groups from different parts of the world to focus on a common goal. Their projects may all focus on one disease or condition, but examine it from different perspectives and share the newly gained information with each other and the wider scientific community. (shrink)

The debate between impartialists and their critics has dominated both moral and political philosophy for over a decade. Characteristically, impartialists argue that any sensible form of impartialism can accommodate the partial concerns we have for others. By contrast, partialists deny that this is so. They see the division as one which runs exceedingly deep and argue that, at the limit, impartialist thinking requires that we marginalise those concerns and commitments that make our lives meaningful. This book attempts to show both (...) that the dispute between impartialists and their critics runs very deep, and that it can nonetheless be resolved. The resolution begins by asking how impartialist political philosophy can defend the priority of justice when it conflicts with people's commitments to their conceptions of the good. It is argued that priority can only defended if political impartialism has a moral foundation, and that moral foundation must not be a foundation in the ideal of equality (as is often thought), but a foundation in the partial concerns we have for others. In short, impartialist moral philosophy must take our partial concerns as central if it is to gain allegiance. However, if it does take our partial concerns as central, then it can generate a defence of political impartialism which shows why justice must take priority, but which also acknowledges that pluralism about the good is permanent. (shrink)

Language is the species-specific human version of the animal system of communication. In contrast to non-human animals, language enables humans to invent a plurality of possible worlds; reflect upon signs; be responsible for our actions; gain conscious awareness of our inevitable mutual involvement in the network of life on this planet; and be responsibly involved in the destiny of the planet. The author looks at semiotics, the study of signs, symbols, and communication as developing sequentially rather than successively, more synchronically (...) than diachronically. She discusses the contemporary phenomenon that people in today's society have witnessed and participated in, as part of the development of semiotics. Although there is a long history preceding semiotics, in a sense the field is, as a phenomenon, more "of our time" than of any time past. Its leading figures, whom Petrilli examines, belong to the twentieth and twenty-first century. Semiotics is associated with a capacity for listening. This capacity is also the condition for reconnecting to and recovering the ancient vocation of semiotics as that branch of medical science relating to the interpretation of signs or symptoms. The pragmatic aspect of global semiotics studies the impact of language or signs on those who use them, and looks for consequences in actual practice. In this respect, Petrilli theorizes that the task for semiotics in the era of globalization is nothing less than to take responsibility for life in its totality. (shrink)

First published in 1985, the _Handbook for Achieving Gender Equity Through Education_ quickly established itself as the essential reference work concerning gender equity in education. This new, expanded edition provides a 20-year retrospective of the field, one that has the great advantage of documenting U.S. national data on the gains and losses in the efforts to advance gender equality through policies such as Title IX, the landmark federal law prohibiting sex discrimination in education, equity programs and research. Key features include:_ (...) Expertise_ – Like its predecessor, over 200 expert authors and reviewers provide accurate, consensus, research-based information on the nature of gender equity challenges and what is needed to meet them at all levels of education._ Content Area Focus_ – The analysis of gender equity within specific curriculum areas has been expanded from 6 to 10 chapters including mathematics, science, and engineering._ Global/Diversity Focus_ – Global gender equity is addressed in a separate chapter as well as in numerous other chapters. The expanded section on gender equity strategies for diverse populations contains seven chapters on African Americans, Latina/os, Asian and Pacific Island Americans, American Indians, gifted students, students with disabilities, and lesbian, gay, bisexual, and transgender students. _ Action Oriented_ – All chapters contain practical recommendations for making education activities and outcomes more gender equitable. A final chapter consolidates individual chapter recommendations for educators, policymakers, and researchers to achieve gender equity in and through education._ New Material_ – Expanded from 25 to 31 chapters, this new edition includes: *more emphasis on male gender equity and on sexuality issues; *special within population gender equity challenges ; *coeducation and single sex education; *increased use of rigorous research strategies such as meta-analysis showing more sex similarities and fewer sex differences and of evaluations of implementation programs; *technology and gender equity is now treated in three chapters; *women’s and gender studies; *communication skills relating to English, bilingual, and foreign language learning; and *history and implementation of Title IX and other federal and state policies. Since there is so much misleading information about gender equity and education, this _Handbook_ will be essential for anyone who wants accurate, research-based information on controversial gender equity issues—journalists, policy makers, teachers, Title IX coordinators, equity trainers, women’s and gender study faculty, students, and parents. (shrink)

(From the Publisher 2017) Featuring many important updates and revisions, the highly-anticipated second edition of The Blackwell Companion to Consciousness offers a collection of readings that together represent the most thorough and comprehensive survey of the nature of consciousness available today. Chapters delve deeply into the wide variety of scientific and philosophical problems that arise from the study of consciousness—as well as the philosophical, cognitive, neuroscientific, and phenomenological approaches to solving them. -/- Along with updates to existing scientific readings reflecting (...) the latest research data, this edition features 18 entirely new theoretical, empirical and methodological chapters covering such areas as integrated information theory, the resurgence in panpsychism, the renewed interest in more sophisticated first-person methodologies for the investigation of conscious phenomenology, and many others. Featuring contributions by leading experts in the study of consciousness, from across a variety of academic disciplines, the 54-chapter collection reasserts its role as the most thorough, authoritative, and up-to-date survey of the subject available today. Illuminating and thought-provoking, The Blackwell Companion to Consciousness, Second Edition is an indispensable resource for those wishing to gain insights into the latest contemporary thinking on consciousness. (shrink)

METCO, America’s longest-running voluntary school desegregation program, has for 34 years bused black children from Boston’s city neighborhoods to predominantly white suburban schools. In contrast to the infamous violence and rage of forced school busing within the city in the 1970s, METCO has quietly and calmly promoted school integration. How has this program affected the lives of its graduates? Would they choose to participate if they had it to do over again? Would they place their own children on the bus (...) to suburbia? Sixty-five METCO graduates vividly recall their own stories in this revealing book. Susan E. Eaton interviewed program participants who are now adults, asking them to assess the benefits and hardships of crossing racial and class lines on their way to school. Their answers poignantly show that this type of racial integration is not easy—they struggled to negotiate both black and white worlds, often feeling fully accepted in neither. Even so, nearly all the participants believe the long-term gains outweighed the costs and would choose a similar program for their own children—though not without conditions and apprehensions. Even as courts and policymakers today are forcing the abandonment of desegregation, educators warn that students are better prepared in schools that reflect our national diversity. This book offers an accessible and moving account of a rare program that, despite serious challenges, provides a practical remedy for the persistent inequalities in American education. (shrink)

Nobody seriously doubts the possibility, or the usefulness, of finding things out; that is something we all take for granted when we inquire about our plane schedule, the state of our bank account, the best treatment for our child's illness, and so forth – a presupposition of the most ordinary, everyday looking into things as well as of the most sophisticated scientific research, not to mention of the legal system. Of course, nobody seriously doubts, either, that sometimes, instead of really (...) looking into things, people fake, fudge, and obfuscate to avoid discovering unpalatable truths or having to give up comfortable tenets; that is something we all take for granted when we ask who paid for a reassuring (or a damning) study, who stands to gain from an Official Inquiry, which party an expert witness works for, and so on. -/- Of late, however, radical feminists, multiculturalists, sociologists and rhetoricians of science, and (I am embarrassed to say) a good many philosophers as well – though they look into questions about their plane schedules, bank accounts, medical treatments, etc., just like everyone else – profess to have seen through what the rest of us take for granted. (shrink)

This article critiques peter van inwagen's application of quinean ontology to the problem of whether fictional entities exist. It is argued that nothing is gained by considering fictional entities to be theoretical entities, And that van inwagen's claim that fictional entities 'hold' rather than 'have' certain properties does not avoid logical difficulties and is inconsistent with his commitment to quinean ontology.

Philosophical discussion of Alan Turing’s writings on intelligence has mostly revolved around a single point made in a paper published in the journal Mind in 1950. This is unfortunate, for Turing’s reflections on machine (artificial) intelligence, human intelligence, and the relation between them were more extensive and sophisticated. They are seen to be extremely well-considered and sound in retrospect. Recently, IBM developed a question-answering computer (Watson) that could compete against humans on the game show Jeopardy! There are hopes it can (...) be adapted to other contexts besides that game show, in the role of a collaborator of, rather than a competitor to, humans. Another, different, research project—an artificial intelligence program put into operation in 2010—is the machine learning program NELL (Never Ending Language Learning), which continuously ‘learns’ by ‘reading’ massive amounts of material on millions of web pages. Both of these recent endeavors in artificial intelligence rely to some extent on the integration of human guidance and feedback at various points in the machine’s learning process. In this paper, I examine Turing’s remarks on the development of intelligence used in various kinds of search, in light of the experience gained to date on these projects. (shrink)

Usually viewed as the premier apologist for laissez-faire capitalism, Smith is seen in this new interpretation within the context of an earlier tradition that condemned the British aristocracy for relinquishing its moral obligation to promote the public good in favor of an unceasing pursuit of private gain. Through separate chapters on Mandeville, Bolingbroke, and Hume, Gallagher shows that Smith echoed civic humanist sermons against the avaricious inclinations of the nobles who profited most from commercial expansion. Unlike earlier critics, however, Smith (...) concluded that the most prudent response to aristocratic corruption was not to hold ministers, kings, and social notables to higher standards but to limit their access to political power. _The Rule of the Rich?_ accordingly shows that the case for limited government made in _The Wealth of Nations_ was not a defense of individual liberty so much as a concession to the apparent incompetence of the British upper class. (shrink)

Usually viewed as the premier apologist for laissez-faire capitalism, Smith is seen in this new interpretation within the context of an earlier tradition that condemned the British aristocracy for relinquishing its moral obligation to promote the public good in favor of an unceasing pursuit of private gain. Through separate chapters on Mandeville, Bolingbroke, and Hume, Gallagher shows that Smith echoed civic humanist sermons against the avaricious inclinations of the nobles who profited most from commercial expansion. Unlike earlier critics, however, Smith (...) concluded that the most prudent response to aristocratic corruption was not to hold ministers, kings, and social notables to higher standards but to limit their access to political power. _The Rule of the Rich?_ accordingly shows that the case for limited government made in _The Wealth of Nations_ was not a defense of individual liberty so much as a concession to the apparent incompetence of the British upper class. (shrink)

To get an idea of how personalized medicine could reshape patient care in the years ahead, one need only look at how it is beginning to reshape the care of patients with cancer. Cancer is where personalized medicine has gained its firmest foothold. The longstanding scattershot practice of prescribing the same drugs to virtually all patients with a particular type of cancer is giving way to a more selective approach in which genetic tests are run on tumor samples to identify (...) which patients are likely to benefit from which drugs, or to tell whether they need drugs at all. This shift holds the prospect of improving cancer care and the stewardship of costly cancer care resources. It has had its successes and failures .. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Sympathy in Mind (1876–1900)Susan LanzoniIn the April 1884 issue of Mind, William James published his influential account of emotion, which stressed the bodily and physiological constitution of various feeling-states.1 The article reflected new trends in physiological psychology, but came under attack by numerous respondents in the journal who argued that there was more to the emotions than physiology.2 As the evolutionary psychologist Hiram Stanley intoned, "emotions in the (...) higher stages are filled out by knowledge and will."3 Many noted that the higher emotions—aesthetic sentiments, sympathy, pity, envy, love—were not marked by clear physiological changes. Charles Darwin had observed that love was not discernable by prominent facial expressions.4 There was also little agreement as to how to divide sentiments from appetites, affections, and passions. What came to be known as the James-Lange theory [End Page 265] of emotion, then, was only one of a variety of theories of emotion circulating in Anglo-American intellectual culture of the late nineteenth century.5In debates about the nature of emotion, the higher emotions—particularly that of sympathy—played a crucial role. Sympathy was most often understood to be a kind of tenderheartedness linked to, but distinct from love. At the same time, sympathy was tethered to a variety of moral and epistemological ends—as a cornerstone in evolutionary ethics, an element in aesthetic appreciation, and even as a source for knowledge of other minds. Sympathy had had a prominent place in eighteenth-century theories of aesthetics, moral sentiments and taste, in the writings of Adam Smith and Edmund Burke. In the late Victorian period, theories of sympathy drew on this lineage and increasingly became tinged with evolutionary and developmental features.Although sympathy in the Victorian period has gained the attention of literary scholars, historians of the mind sciences have not paid it much due, even though its psychological origins and moral correlates were of sustained interest in this period.6 Stefan Collini has argued that British intellectual culture was intrigued by the interplay of egoistic and altruistic tendencies, and the birth of a number of ethical societies in the final two decades of the century attests to the increased emphasis on the moral dimensions of sympathy.7 Anti-vivisection movements and societies for the prevention of cruelty to animals and children, often with appeals to sympathy, gained adherents in this period in Britain and America.8 In one study, [End Page 266] psychologists distributed scientific questionnaires in order to assess the experiences of sympathy and pity of nearly four hundred subjects.9 There was no underestimating the importance of sympathy for Anglo-American intellectuals, who confidently claimed it was becoming more refined and more widely diffused in their era. Darwin believed that sympathy had been extended to those of the same nation, and prescriptively wrote that it should extend to all nations and races, as well as the imbecile and the maimed. Darwin was echoing here the broader enlightenment sentimentalist tradition that linked the feeling of sympathy to a conception of humanity.10In the pages of the British professional psychological and philosophical journal Mind, sympathy was under scrutiny by scholars in evolutionary and developmental psychology, ethics, and aesthetics. This journal, first published in 1876, and funded by Alexander Bain, examined new trends in physiological and scientific psychology and sought a broad philosophical framework for the understanding of mental life.11 It played a mediating role in the overlapping discussions of science and philosophy and published on a diverse array of topics. Although Mind saw itself as a specialized journal for psychology and philosophy, it was founded at an historical moment when discussions of the mind were not narrowly portioned out to the psychological sciences, as would increasingly be the case after 1900. Indeed, the experimental psychological laboratory emerged as a new scientific institution [End Page 267] only in 1879 with Wilhelm Wundt's Leipzig laboratory, and then in 1897 at the Universities of London and Cambridge. Specialization in the late Victorian age on topics relating to the mind was downright eclectic: during the editorships of George Croom Robertson (1876–1892) and of G.F. Stout (1892–1920), Mind published on physiological... (shrink)

Developmental psychologists have long recognized the extraordinary influence of action on learning (Held & Hein, 1963; Piaget, 1952). Action experiences begin to shape our perception of the world during infancy (e.g., as infants gain an understanding of others’ goal-directed actions; Woodward, 2009) and these effects persist into adulthood (e.g., as adults learn about complex concepts in the physical sciences; Kontra, Lyons, Fischer, & Beilock, 2012). Theories of embodied cognition provide a structure within which we can investigate the mechanisms underlying action’s (...) impact on thinking and reasoning. We argue that theories of embodiment can shed light on the role of action experience in early learning contexts, and further that these theories hold promise for using action to scaffold learning in more formal educational settings later in development. (shrink)

By the late 1980s, Government and Binding Theory - which was central to almost all research in generative grammar - threatened to become as large and as intricate as the language it described. To counter this, Noam Chomsky introduced a minimalist program with the aim of making explanations of language as simple and general as possible. It has since gained widespread acceptance, to the extent that the most recent first-year textbook in syntax is based on it. One of the areas (...) subjected to this minimalist scrutiny has been phrase structure, the fundamental basis of grammar. This book focuses on the most controversial area of phrase structure, the notion of specifiera notion encompassing the traditional categories of subjects, possessors, determiners, auxiliaries, and adjuncts. It examines what place the notion has in the new theory and how the projection of specifiers is to be eliminated or extended. The contributors draw on empirical, theoretical research in cross-linguistic phenomena and first and second language acquisition. The substantial introductory chapter provides an up-to-date account of minimalist syntactic theory and a critical evaluation of the notion of specifier within it. (shrink)

In this article, drawing upon a feminist epistemology, we examine the critical roles that philosophical standpoint, historical usage, gender, and language play in a knowledge arena which is increasingly opaque to the general public. Focussing on the language dimension in particular, in its historical and social dimensions, we explicate how some keywords in use across artificial intelligence (AI) discourses inform and misinform non-expert understandings of this area. The insights gained could help to imagine how AI technologies could be better conceptualised, (...) explained, and governed, so that they are leveraged for social good. (shrink)

Nobody seriously doubts the possibility, or the usefulness, of finding things out; that is something we all take for granted when we inquire about our plane schedule, the state of our bank account, the best treatment for our child's illness, and so forth – a presupposition of the most ordinary, everyday looking into things as well as of the most sophisticated scientific research, not to mention of the legal system. Of course, nobody seriously doubts, either, that sometimes, instead of really (...) looking into things, people fake, fudge, and obfuscate to avoid discovering unpalatable truths or having to give up comfortable tenets; that is something we all take for granted when we ask who paid for a reassuring study, who stands to gain from an Official Inquiry, which party an expert witness works for, and so on.Of late, however, radical feminists, multiculturalists, sociologists and rhetoricians of science, and a good many philosophers as well – though they look into questions about their plane schedules, bank accounts, medical treatments, etc., just like everyone else – profess to have seen through what the rest of us take for granted. (shrink)

Why wasn’t Hume a sceptic about matters of taste? He was a thoroughgoing sceptic about fundamental matters in traditional metaphysics, such as cause, causal necessitation, inductive inferences, the self, even external objects. Yet, without exception, Hume’s aesthetics is read as abruptly reversing his sceptical position and promoting a timeless and objective standard for judging beauty. I reject the dominant approach for displacing the gains of his scepticism. To impute to Hume knowledge of a standard that depends essentially on a relation (...) to certain persons makes him sound more like an idealist than an empiricist philosopher with naturalistic leanings. Instead, I read his aesthetic naturalism against the background of his sceptical commitments, by reconstructing his dilemma of taste along the lines of his general scepticism about cause. I argue that he deduces ‘that’ an unknown standard is operative, but in a qualified sense not ruled out by his scepticism. (shrink)

In pediatric emergency rooms (ERs), social workers must navigate diverse responsibilities including acting as advocates and liaisons between families and multidisciplinary treatment teams, providing compassionate support to families in crisis, and assessing for and reporting any suspicions of child abuse or neglect. These potentially contrasting roles can place social workers at the center of dealing with ethical dilemmas and advocating against ethical violations, such as bias and discrimination toward families. This qualitative study seeks to gain insight into ethical issues commonly (...) encountered in pediatric ERs by exploring the perspectives of 23 social workers at Level 1 trauma centers in the United States. Thematic analysis was used to develop major themes and subthemes related to ethical violations, dilemmas, and best practices in pediatric ERs. Major themes emerged related to unfair treatment of families (with subthemes of bias, discrimination, and compassion fatigue), ethical dilemmas (with subthemes of cultural issues, safety and system issues), and promoting ethical practices (with subthemes of self-awareness, advocacy, and efforts to change the system). This study provides important insights into ethical issues in pediatric ERs as experienced by social workers and can inform efforts to improve the quality and equity of care for all families in pediatric ERs. (shrink)

Background Currently there is increasing recognition of the need for research in developing countries where disease burden is high. Understanding the role of local factors is important for undertaking ethical research in developing countries. We explored factors relating to information and communication during the process of informed consent, and the approach that should be followed for gaining consent. The study was conducted prior to a family-based genetic study among people with podoconiosis (non-filarial elephantiasis) in southern Ethiopia. Methodology/Principal Findings We adapted (...) a method of rapid assessment validated in The Gambia. The methodology was entirely qualitative, involving focus-group discussions and in-depth interviews. Discussions were conducted with podoconiosis patients and non-patients in the community, fieldworkers, researchers, staff of the local non-governmental organisation (NGO) working on prevention and treatment of podoconiosis, and community leaders. We found that the extent of use of everyday language, the degree to which expectations of potential participants were addressed, and the techniques of presentation of information had considerable impact on comprehension of information provided about research. Approaching podoconiosis patients via locally trusted individuals and preceding individual consent with community sensitization were considered the optimal means of communication. Prevailing poverty among podoconiosis patients, the absence of alternative treatment facilities, and participants' trust in the local NGO were identified as potential barriers for obtaining genuine informed consent. Conclusions Researchers should evaluate the effectiveness of consent processes in providing appropriate information in a comprehensible manner and in supporting voluntary decision-making on a study-by-study basis. (shrink)

This article examines continuity and change in Star trek’s expression of the American Frontier Myth, moving from an American ideal of imperialist expansion across an unlimited feminized landscape and destruction of Indians and animals in the myth’s early form, to one of benevolent redemption of the Other as misguided or evil alien in the unlimited expanse of outer space in early Star Trek. Analysis of symbol and narrative in Star Trek Voyager show further change, as feminist and environmental ethics are (...) included. Now, movement is toward earth rather than away from it, raced and gendered Others are often internalized rather than projected onto Indians and aliens, and nature is vulnerable and spiritual rather than unlimited and inert. Though women and nature are still linked and idealized as selfless givers, progress is also made as women gain equal rank and air time and men take on some traditionally feminine roles. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 43.1 (2005) 83-105 [Access article in PDF] Does Malebranche Need Efficacious Ideas? The Cognitive Faculties, the Ontological Status of Ideas, and Human Attention Susan Peppers-Bates But whatever effort of mind I make, I cannot find an idea of force, efficacy, of power, save in the will of the infinitely perfect Being. Malebranche, Elucidation 15 One of the signatures of 17th century rationalists (...) is their replacement of the Scholastics's dependence on the deliverances of the senses with a dependence on the deliverances of the intellect as the key to gaining knowledge.1 Correct use of the intellect leading to freedom from the passions and to certain knowledge figures prominently in the works of Spinoza and Leibniz. Descartes's Meditations uses skeptical doubt to withdraw the mind from the senses, and his reliance on the meditative genre not only reveals to his readers the intellect as a distinct source of knowledge, but also trains them to use properly their will or faculty of judgment. Commentators have argued persuasively that overthrowing the sense-based epistemology and metaphysics of the Aristotelians depended on "discovering" the primacy of one's intellect over the senses, and using the deliverances of the mind to establish solid foundations for a new metaphysics and epistemology.2 Indeed, [End Page 83] outlining the proper use of the mind's faculties arguably lay at the basis of the Cartesian program in particular. This importance can be seen in Arnauld and Nicole's influential Port-Royal Logic, which aimed at training its readers in the proper use of the intellect.3Few would question Nicolas Malebranche's inclusion in the rationalist tradition.4 For while Malebranche famously takes ideas out of the Cartesian mind and transports them to God's—thus privileging the divine over the natural light—he shares Descartes's belief that our intellect, not our senses, holds the key to metaphysical truths such as the essence of matter, the mind-body distinction, and the existence of God.5 Yet, recently, Nicholas Jolley has contended that Malebranche's later commitment to "efficacious ideas" undermines his earlier belief in the power of the cognitive faculties: he believes that Malebranche abandons his view that the mind makes "real use" of the intellect to know intelligible objects.6 Jolley's position builds upon Alquié and Robinet's claims that around 1694-95 Malebranche moved from a vision "in" God to a vision "by" God. Now God's ideas act on and modify the soul with both sensations and intellectual concepts, rather than the human intellect contemplating ideas in the Divine Reason.7Alquié and Robinet argue that Malebranche, pushed by the battles with Arnauld and Régis over the status of ideas, introduced the language of "efficacious" ideas to explain how the union of the human and the divine mind is supposed to work.8 Robinet in particular suggests that in cashing out the metaphor of God enlightening human minds, Malebranche moved from a static "ontologist" view of idea-objects in God to an active "illuminationist" view whereby divine ideas cause(intellectual [End Page 84] and sensory) perception by modifying the soul.9 Once one accepts this view of the place and function of efficacious ideas in Malebranche's metaphysics, it seems natural to accept Jolley's declaration that the only way for the mind to apprehend ideas in God is if those ideas "act directly on the mind; [if] they thereby cause cognitive states to arise in a substance which is devoid of all genuine cognitive capacities of its own."10 Indeed, Jolley suggests that Malebranche ultimately made the soul passive in all its states, including its volitional ones.11In this paper, I argue that a strong interpretation of efficacious ideas, whereby they appear to become true causal agents, must be rejected precisely because it pushes us into an incorrect reading of Malebranche's theory of the divine and human faculties. Making ideas true causal agents within God privileges divine reason at the... (shrink)

The impact of stress and other psychological variables on Inflammatory Bowel Disease prognosis, treatment response, and functional level is well-established; however, typical IBD treatment focuses on the physiological pathology of the disease and neglects complementary stress-reducing interventions. Recent pilot studies report the benefits of mindfulness-based interventions in people living with IBD, but are limited by small sample sizes. Recruitment challenges to in-person studies may be in part due to the difficulty IBD patients often have adhering to fixed schedules and travel (...) as a result of IBD symptoms such as pain, fatigue, and incontinence. The current study aimed to address this barrier by offering participants access to online mindfulness training, allowing individuals to engage with intervention materials to fit their own schedule. Online mindfulness programs have gained popularity in recent years, as they increase access and flexibility and decrease cost to the user; however, the dropout rate tends to be high. The current study compared the rate of adherence and efficacy of mindfulness training as a function of level of support: self-guided versus supported. Analysis revealed no significant difference in the benefits received between participants in the two groups; however, a significant difference group was found in terms of rate of completion, with 44.1% of the supportive group completing the protocol compared to 11.7% of the self-guided. Common challenges to meditation were measured, but did not significantly predict adherence to the intervention, and experience of these challenges did not significantly change over the duration of the study. Implications of the current research, future directions for the use of MBI for IBD patients, and a discussion of methodological considerations are provided. (shrink)

Did protolanguage users use discrete words that referred to objects, actions, locations, etc., and then, at some point, combine them; or on the contrary did they have words that globally indexed whole semantic complexes, and then come to divide them? Our answer is: early humans were forming language units consisting of global and discrete dimensions of semiosis in dynamic opposition. These units of thinking-for-speaking, or ‘growth points’ (GPs) were, jointly, analog imagery (visuo-spatio-motoric) and categorically-contrastive (-emic) linguistic encodings. This discrete-global duality (...) was a new mode of embodied cognition that enabled thinking and acting in new ways: the dawn of protolanguage. Where did this mode of cognition come from? We have some suggestions based on the hypothesis that gestures gained the power to orchestrate actions, manual and vocal, with significances other than those of the actions themselves, giving rise to cognition framed in the proposed dual terms. Note, however, our proposal is not one of the ‘gesture-first’ theories of language origins. Such theories predict what did not evolve: a language of pantomime; rather than what did evolve: an integrated system of synchronized gestures and spoken forms. GP theory is an account of the cognition underlying such an integrated system. A scenario for the evolutionary selection of this cognitive mode is ‘Mead’s Loop’, a model in which one’s cognition is enriched by one’s own gestures, insofar as they are objects in social interactions. (shrink)