In a sense, all technology is biotechnology: machines interacting with human organisms. Technology is designed to overcome the frailties and limitations of human beings in a state of nature -- to make us faster, stronger, longer-lived, smarter, happier. And all technology raises questions about its real contribution to human welfare: are our lives really better for the existence of the automobile, television, nuclear power? These questions are ethical and political, as well as medical; and they even reach to the philosophical (...) and spiritual. On the whole, we seem pretty well adapted to our technology, at least on the face of it -- but there have always been doubts about whether the human soul thrives best in the oppressively technological world we have created for ourselves. (I am continually struck by how much time I have to spend fixing the machines that supposedly improve my life.). (shrink)

Ever since its first publication in 1992, The End of History and the Last Man has provoked controversy and debate. Francis Fukuyama's prescient analysis of religious fundamentalism, politics, scientific progress, ethical codes, and war is as essential for a world fighting fundamentalist terrorists as it was for the end of the Cold War. Now updated with a new afterword, The End of History and the Last Man is a modern classic.

「仁」と「天理」はどう語られてきたか―『春秋』三伝・『論語』をはじめとする経典類から二十四史まで、さらに「侯馬盟書」等の出土史料を渉猟して「仁」の原義とその変質、「天理」観との関わりを検討し、その観念 と暦・天文・度量衡・十二方位・楽・易との関係、建築物への數理的表象に説き及ぶ。.

Francis Fukuyama's controversial new book, Our Posthuman Future: Consequences of the Biotechnology Revolution, has elicited varied reactions, but like it or not, it seems likely to be influential. Here are three opinions. —Ed.

Francis Fukuyama is one of the most significant political theorists of the past thirty years. Bursting into public awareness in 1989 with his provocative thesis about "the end of history," Fukuyama has made fascinating contributions to a wide range of subjects - the importance of trust in societies, the potential dangers of biotechnology, the development of political authority and the modern state, and most recently, the role of identity in politics. This book records a series of conversations with Fukuyama in (...) which he discusses his background and its role in shaping his thinking, the context and genesis of his major works, and his thoughts in light of the dramatic developments of the past decade, especially the rise of populism around the world. The result is a fascinating picture of a major intellectual. The book both provides an overview of Fukuyama's thought and reveals new insights into his best-known work. This book also allows readers to trace the themes which have animated Fukuyama's entire intellectual career. (shrink)

The objective of this study is to design a laboratory experiment to explore the effect of ambiguity on a subject’s search behavior in a finite-horizon sequential search model. In so doing, we employ a strategy to observe the potential trend of reservation points that is usually unobserved. We observe that subjects behaving consistently across treatments reduce their reservation points in the face of ambiguity over point distribution. Our result is consistent with the theoretical implication obtained by Nishimura and Ozaki.

Clinical ethics support, including ethics consultation, has become established in the field of medical practice throughout the world. This practice has been regarded as useful, most notably in the UK and the USA, in solving ethical problems encountered by both medical practitioners and those who receive medical treatment. In Japan, however, few services are available to respond to everyday clinical ethical issues, although a variety of difficult ethical problems arise daily in the medical field: termination of life support, euthanasia and (...) questions about patient autonomy. In light of these conditions, a group of 17 volunteer educators and researchers from the area of biomedical ethics, including the authors, have formed the Clinical Ethics Support and Education Project, and began providing Japan’s first small team clinical ethics consultation service in October, 2006. Members include scholars of biomedical ethics, scholars of philosophy and ethics, legal professionals and legal scholars, nurses and doctors, consisting of five women and 12 men. Consultation teams, made up of a small number of members, were organised each time a request for consultation was received. Over approximately 15 months (October 2006–December 2007), the programme received 22 consultation requests from medical practitioners and medical institutions, and three from the families of patients. In this paper, we will discuss the status of our consultation service and examples of consultation cases we have handled. In addition, we will examine the process of evaluating small team clinical ethics consultation services, as well as the strengths and weakness of such programmes. (shrink)

In the past thirty years, the United States has undergone a profound transformation in its social structure: Crime has increased, trust has declined, families have broken down, and individualism has triumphed over community. Has the Great Disruption of recent decades rent the fabric of American society irreparably? In this brilliant and sweeping work of social, economic, and moral analysis, Francis Fukuyama shows that even as the old order has broken apart, a new social order is already taking its place. The (...) Great Disruption forges a new model for understanding the Great Reconstruction that is under way. (shrink)

This paper proposes a class of independence axioms for simple acts. By introducing the E\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathcal {E}}$$\end{document}-cominimum independence axiom that is stronger than the comonotonic independence axiom but weaker than the independence axiom, we provide a new axiomatization theorem of simple acts within the framework of Choquet expected utility. Furthermore, in order to provide the axiomatization of simple acts, we generalize Kajii et al. into an infinite state space. Our axiomatization theorem relates (...) Choquet expected utility to multi-prior expected utility through the core of a capacity that is explicitly derived within our framework. Our result in this paper also derives Gilboa, Eichberger and Kelsey, and Rohde as a corollary. (shrink)

This article analyzes investors’ portfolio selection problems in a two-period dynamic model of Knightian uncertainty. We account for the existence of portfolio inertia in this two-period framework. Furthermore, by incorporating investors’ updating behavior, we analyze how observing new information in the first period will affect investors’ behavior. By this analysis, we show that observing new information in the first period will expand portfolio inertia in the second period compared with the case in which observing new information has not been gained (...) in the first period if the degree of Knightian uncertainty is sufficiently large. (shrink)

意味の研究は、言語研究の中でも比較的歴史が新しい。はじめに、語や文の意味とは何か、意味をどう記述するかをめぐる基本的な問題を明らかにする。そして、意味の形式化を徹底したモンタギュー意味論の展開と、言語 現象を人間の認知過程の反映ととらえた認知的意味論の方法論について紹介する。その後、自然言語処理における意味と概念の表現とその計算機構について解説する。.

A circadian clock, with physiological characteristics similar to those of eukaryotes, functions in the photosynthetic prokaryote, cyanobacteria. The molecular mechanism of this clock has been efficiently dissected using a luciferase reporter gene that reports the status of the clock. A circadian clock gene cluster, kaiABC, has been cloned via rhythm mutants of cyanobacterium, Synechococcus, and many clock mutations mapped to the three kai genes. Although kai genes do not share any homology with clock genes so far identified in eukaryotes, analysis (...) of their expression suggests that a negative feedback control of kaiC expression by KaiC generates the circadian oscillation and that KaiA functions as a positive factor to sustain this oscillation. BioEssays 22:10–15, 2000. ©2000 John Wiley & Sons, Inc. (shrink)

The argument contained in The End of History and the Last Man consists of an empirical part and a normative part: critics have confused the two and their proper relationship. The assertion that we have reached the "end of history" is not a statement about the empirical condition of the world, but a normative argument concerning the justice or adequacy of liberal democratic political institutions. The normative judgment is critically dependent on empirical evidence concerning, for example, the workability of capitalist (...) and socialist economic systems, but ultimately rests on supra-empirical grounds. The empirical part concerns whether there is something like the Hegelian-Marxist concept of History as a coherent, directional evolution of human societies taken as a whole. The answer to this is yes, and lies in the phenomenon of economic modernization based on the directional unfolding of modern natural science. The latter has unified mankind to an unprecedented degree, and gives us a basis for believing that there will be a gradual spread of democratic capitalist institutions over time. This empirical conclusion, however, does no more than give us hope that there is a progressive character to world history, and does not prove the normative case. The normative grounding of modern liberal democracy has indeed been put in jeopardy by the philosophical "crisis of modernity" inaugurated by Nietzsche and Heidegger. Contemporary postmodernist critiques of the possibility of such a grounding have not, however, adequately come to terms with the destructive consequences of their views for liberal democratic societies. This aporia, discussed most seriously in the Strauss-Kojève debate, is the central intellectual issue of our age. (shrink)

本書では、水戸学の探究のためにも現代水戸学論の批判と修正を図りつつ、虚心坦懐に水戸の先人が求めたところを明らかにする。水戸学に革命論が存在するか?水戸学に徂徠学の影響が認められるか?また、関連する続編 や論賛の問題にも考察を加える。.

後期水戸学の中心的存在で水戸学の本流であった藤田幽谷の青少年期の学問成果に注目し、その形成の一端を明らかにする。幽谷門下の吉田活堂を中心とする水戸の国学、そして『大日本史』や『扶桑拾葉集』の研究を経て 辿り着く、幽谷研究の決定版。.

本書は、戦国時代の混乱を武力を以て終わらせた徳川家康の統治思想が、日本の公共哲学の原型であるという意表を突く主張から始まる。そして、家康に淵源し、以後250年に及ぶ平和と安定を支えた公共哲学を、鈴木正 三、『葉隠』、白隠慧鶴、太宰春台、海保青陵、そして福澤諭吉の思想に探ってゆくのである。西欧のヒューマニズムが基づく軍事と土地所有ではなく、軍事と商業。すなわち、武士と商人の相互性と、両者のバランス感覚 としてのヒューマニズム、そしてそれが育んだ自生的秩序が日本の公共性の核心にあることを、「慈悲」と「正直」を鍵語に解き明かす。現代の公共哲学に歴史からの再考を迫る、知的冒険の書である。.