This book provides an introduction to applied statistical mechanics by considering physically realistic models. It provides a simple and accessible introduction to theories of thermal fluctuations and diffusion, and goes on to apply them in a variety of physical contexts. The first part of the book is devoted to processes in thermal equilibrium, and considers linear systems. Ideas central to the subject, such as the fluctuation dissipation theorem, Fokker-Planck equations and the Kramers-Kroenig relations are introduced during the (...) course of the exposition. The scope is then expanded to include non-equilibrium systems and also illustrates simple nonlinear systems. This book will be of interest to final year undergraduate and graduate students studying statistical mechanics, plasma physics, basic electronics, solid state physics and anyone who wants an accessible introduction to the subject. (shrink)

The main goal of this paper is to present the Marian Smoluchowski’s work on thermal and primordial fluctuations which are the main cause of Brownian motion and one of the first empirical evidences for molecular structure of matter.

The traditional formalism of quantum mechanics is mainly used to describe ensembles of identical systems (with a density-operator formalism) or single isolated systems, but is not capable of describing single open quantum objects with many degrees of freedom showing pure-state stochastic dynamical behaviour. In particular, stochastic 'line-migration' as in single-molecule spectroscopy of defect molecules in a molecular matrix is not adequately described. Starting with the Bohr scenario of stochastic quantum jumps (between strict energy eigenstates), we try to incorporate more general (...) pure-state stochastic dynamical behaviour into the quantum mechanical formalism.Probability distributions of (approximately) pure states, arising through the stochastic pure-state dynamics for long times, give rise to appropriate decompositions of thermal density operators. These decompositions of density operators into pure states mediate between quantum mechanics for ensembles of molecules and quantum theory for single molecules (or single dressed quantum objects). We suggest that such decompositions should be consistent with infinite limits (e.g. the Born-Oppenheimer limit for infinite nuclear masses) in the sense that quantum fluctuations (around classical behaviour in the infinite limit) die out asymptotically. (shrink)

It is shown that if mental influence can change a position or momentum coordinate within the limits of the uncertainty principle, such change, when magnified by a single interaction, is sufficient to order the direction of traveling molecules. Mental influence could initiate an action potential in the brain through this process by using the impact of ordered molecules to open the gates of sodium channels in neuronal membranes. It is shown that about 80 ordered molecules, traveling at thermal velocity (...) in the intercellular medium in the brain, can break an ionic or covalent bond, and that the number needed to initiate an action potential is relatively small. If mental influence can act within the brain, it is reasonable to suppose it can act to some extent outside of it. If mental influence could not only order the direction of individual molecules, but coordinate this effect to produce a longitudinal pressure wave which is reasonably coherent across a macroscopic surface, only 10^4 molecules need be simultaneously affected to produce a detectible sound wave. Such an effect is not ordinarily observed, which suggests that if mental influence acts by ordering the direction of molecules, it acts at the level of individual molecules, but does not coordinate their motion. (shrink)

We present a framework for analyzing black hole backreaction from the point of view of quantum open systems using influence functional formalism. We focus on the model of a black hole described by a radially perturbed quasi-static metric and Hawking radiation by a conformally coupled massless quantum scalar field. It is shown that the closed-time-path (CTP) effective action yields a non-local dissipation term as well as a stochastic noise term in the equation of motion, the Einstein–Langevin equation. Once the (...) class='Hi'>thermal Green's function in a Schwarzschild background becomes available to the required accuracy, the strategy described here can be applied to obtain concrete results on backreaction. We also present an alternative derivation of the CTP effective action in terms of the Bogolyubov coefficients, thus making a connection with the interpretation of the noise term as measuring the difference in particle production in alternative histories. (shrink)

Landauer's Principle asserts that there is an unavoidable cost in thermodynamic entropy creation when data is erased. It is usually derived from incorrect assumptions, most notably, that erasure must compress the phase space of a memory device or that thermodynamic entropy arises from the probabilistic uncertainty of random data. Recent work seeks to prove Landauer’s Principle without using these assumptions. I show that the processes assumed in the proof, and in the thermodynamics of computation more generally, can be combined to (...) produce devices that both violate the second law and erase data without entropy cost, indicating an inconsistency in the theoretical system. Worse, the standard repertoire of processes selectively neglects thermal fluctuations. Concrete proposals for how we might measure dissipationlessly and expand single molecule gases reversibly are shown to be fatally disrupted by fluctuations. Reversible, isothermal processes on molecular scales are shown to be disrupted by fluctuations that can only be overcome by introducing entropy creating, dissipative processes. (shrink)

Equilibrium states are used as limit states to define thermodynamically reversible processes. When these processes are implemented in statistical physics, these limit states become unstable and can change with time, due to thermal fluctuations. For macroscopic systems, the changes are insignificant on ordinary time scales and what little there is can be suppressed by macroscopically negligible, entropy-creating dissipation. For systems of molecular sizes, the changes are large on short time scales and can only sometimes be suppressed with significant (...) entropy-creating dissipation. As a result, at molecular scales, thermodynamically reversible processes are impossible in principle, even as approximations, when we account for all sources of dissipation. (shrink)

The translocation of tRNAs through the ribosome proceeds through numerous small steps in which tRNAs gradually shift their positions on the small and large ribosomal subunits. The most urgent questions are: (i) whether these intermediates are important; (ii) how the ribosomal translocase, the GTPase elongation factor G (EF‐G), promotes directed movement; and (iii) how the energy of GTP hydrolysis is coupled to movement. In the light of recent advances in biophysical and structural studies, we argue that intermediate states of translocation (...) are snapshots of dynamic fluctuations that guide the movement. In contrast to current models of stepwise translocation, kinetic evidence shows that the tRNAs move synchronously on the two ribosomal subunits in a rapid reaction orchestrated by EF‐G and GTP hydrolysis. EF‐G combines the energy regimes of a GTPase and a motor protein and facilitates tRNA movement by a combination of directed Brownian ratchet and power stroke mechanisms. (shrink)

The Brownian motion of small particles interacting with a field at a finite temperature is a well-known and well-understood phenomenon. At zero temperature, even though the thermal fluctuations are absent, quantum fields still possess vacuum fluctuations. It is then interesting to ask whether a small particle that is interacting with a quantum field will exhibit Brownian motion when the quantum field is assumed to be in the vacuum state. In this paper, we study the cases of a (...) small charge and an imperfect mirror interacting with a quantum scalar field in (1 + 1) dimensions. Treating the quantum field as a classical stochastic variable, we write down a Langevin equation for the particles. We show that the results we obtain from such an approach agree with the results obtained from the fluctuation-dissipation theorem. Unlike the finite temperature case, there exists no special frame of reference at zero temperature and hence it is essential that the particles do not break Lorentz invariance. We find that that the scalar charge breaks Lorentz invariance, whereas the imperfect mirror does not. We conclude that small particles such as the imperfect mirror will exhibit Brownian motion even in the quantum vacuum, but this effect can be so small that it may prove to be difficult to observe it experimentally. (shrink)

In this paper, we examine the pioneering research on electronic noise—the current fluctuations in electronic circuit devices due to their intrinsic physical characteristics rather than their defects—in Germany and the U.S. during the 1910s–1920s. Such research was not just another demonstration of the general randomness of the physical world Einstein’s work on Brownian motion had revealed. In contrast, we stress the importance of a particular engineering context to electronic noise studies: the motivation to design and improve high-gain thermionic-tube amplifiers (...) for radio and wired communications. Engineering scientists’ endeavors to understand electronic noise started in 1918, when Walter Schottky at Siemens formulated a theory of “shot noise,” current fluctuations owing to the random emissions of discrete electrons in a tube. Schottky’s theory was revised and experimentally tested at Siemens, General Electric, and AT&T during the 1920s, leading to the discoveries of several other types of noise and an increasing interest in the thermal fluctuations in electronic circuits. In 1925–1928, J.B. Johnson and Harry Nyquist at Bell Labs developed a theory of thermal noise for any electrical resistor at a non-zero temperature. Although these studies were initiated to chart the fundamental performance limit of electronic technology, they ended up assisting the empirical determination of individual electronic components’ characteristics. (shrink)

This article presents information about facades, their thermal insulating role in buildings in Albania. The façade in construction is one of the necessary factors to ensure a longer life of the buildings and indoor thermal comfort. Façade systems are composed of different materials, which provide a protective effect during the life of the building. The article will focus on the characteristic materials used in Albania for the construction of facades and the main materials used from the year 2000 (...) up to today. The article will be informative, statistical, and comparative in order to draw conclusions. Nowadays building facades are again becoming one of the main subjects of discussion, undoubtedly due to the increasing importance of the building envelope in relation to energy consumption. In the 90s, minimal attention was paid to the efficiency and quality of facades; everything was done strictly in relation to residency requirements. But, during this last decade, Albania experienced a construction boom, with a series of good new buildings, which are accompanied by progress in the architectural style and in the techniques of building materials usage. However, the advantages of façade systems in construction are not only to make the building long-lasting. The function of facades always undergoes changes and advances over time, in terms of their impact on the temperature fluctuations inside the building or energy storage. (shrink)

The main bioclimatic passive strategies include optimization of the use of natural light, reducing the need for artificial light, maximizing the solar gain using thermal traps and promotion of natural ventilation in order to avoid the need for air conditioning for cooling. The usage of cool air passing through the underground tunnels located in the selected neighborhood in Tirana in order to enhance the cooling process is of huge importance. On the other hand, the building must benefit from the (...) passive solar systems and thermal energy conservation strategies implementing thermal insulation materials. These strategies improve both the indoor comfort and economic aspect. The aim is to be aware of the community for the big benefits of such strategies, increasing the number of passive bioclimatic implementations not only in Albania but also in the region. Through the use of such systems the building can obtain indoor thermal comfort without a traditional cooling system. The passive systems discourage the use of mechanical systems for lighting, cooling, and heating, supporting the natural phenomena such as power of the sun, underground constant temperature, wind direction, and other climate parameters. The selection of the proper thermal insulation materials is complex and sometimes determinant in order to reduce heat gain. The thermal accumulation capacity depends on material width, material type, density, and porosity of the material. The top insulating materials are mostly used in the Tirana. Albania is the expanded polystyrene (EPS). The energy needed for its production is relatively low compared to the other insulating materials. Passive design encourages the application of such kind of materials, reducing the ecological footprint of the buildings. Water recycling is another aspect that bioclimatic design takes into consideration, promoting it. The use of specific materials in order to recycle the rain water through drainage is an important task. The building is faced with significant thermal losses due to the windows. The sizing of the glass area, the orientation, as well as the choice of glass determine the penetration of solar radiation in the building. The selection of the correct type of window is also a complex task. The designer should consider the climate type, the area of the openings, the typology of the window, and the characteristics of the window materials and its thermal performance before implementing it. The usage of the high thermal capacity materials (stone, water) is getting noticed nowadays in bioclimatic and passive building designs. These materials are efficient when having large surfaces and face a strong solar radiation. PCM (phase change materials) are innovative materials that undergo a physical transformation stabilizing the temperature fluctuations in the indoor area of the building archiving and improving thermal comfort parameters inside the building. The typology of such materials and their field of implementation is a very large one. Such materials have resulted to be an added value when implemented and are part of passive systems such as Trombe wall, enhancing its performance. The piezo-electric materials are another group of innovative materials used to gain energy. Their role in energy gaining nowadays is very small but the future belongs to them. The use of such materials is promoted by bioclimatic design benefiting by their mechanical properties, producing electricity. The Empathic house is one of the examples of the future generations. The implementation of some other materials such as ETFE in the building envelope in contrast to glass allows the long-wave penetration inside the building increasing the solar gain capacity. The visibility of such materials is still under examination. (shrink)

Rapid polymerization and depolymerization of actin filaments in response to extracellular stimuli is required for normal cell motility and development. Profilin is one of the most important actin‐binding proteins; it regulates actin polymerization and interacts with many cytoskeletal proteins that link actin to extracellular membrane. The molecular mechanism of profilin has been extensively considered and debated in the literature for over two decades. Here we discuss several accepted hypotheses regarding the mechanism of profilin function as well as new recently emerged (...) possibilities. Thermal noise is routine in molecular world and unsurprisingly, nature has found a way to utilize it. An increasing amount of theoretical and experimental research suggests that fluctuation‐based processes play important roles in many cell events. Here we show how a fluctuation‐based process of exchange diffusion is involved in the regulation of actin polymerization. (shrink)

We consider the simple case of a nonrelativistic charged harmonic oscillator in one dimension, to investigate how to take into account the radiation reaction and vacuum fluctuation forces within the Schrödinger equation. The effects of both zero-point and thermal classical electromagnetic vacuum fields, characteristic of stochastic electrodynamics, are separately considered. Our study confirms that the zero-point electromagnetic fluctuations are dynamically related to the momentum operator p=−i ℏ ∂/∂ x used in the Schrödinger equation.

Some modern cosmological models predict the appearance of Boltzmann Brains: observers who randomly fluctuate out of a thermal bath rather than naturally evolving from a low-entropy Big Bang. A theory in which most observers are of the Boltzmann Brain type is generally thought to be unacceptable, although opinions differ. I argue that such theories are indeed unacceptable: the real problem is with fluctuations into observers who are locally identical to ordinary observers, and their existence cannot be swept under (...) the rug by a choice of probability distributions over observers. The issue is not that the existence of such observers is ruled out by data, but that the theories that predict them are cognitively unstable: they cannot simultaneously be true and justifiably believed. (shrink)

Organisms must adapt to environmental stresses to ensure their survival and prosperity. Different types of stresses, including thermal, mechanical, and hypoxic stresses, can alter the cellular state that accompanies changes in gene expression but not the cellular identity determined by a chromatin state that remains stable throughout life. Some tissues, such as adipose tissue, demonstrate remarkable plasticity and adaptability in response to environmental cues, enabling reversible cellular identity changes; however, the mechanisms underlying these changes are not well understood. We (...) hypothesized that positive and/or negative “Integrators” sense environmental cues and coordinate the epigenetic and transcriptional pathways required for changes in cellular identity. Adverse environmental factors such as pollution disrupt the coordinated control contributing to disease development. Further research based on this hypothesis will reveal how organisms adapt to fluctuating environmental conditions, such as temperature, extracellular matrix stiffness, oxygen, cytokines, and hormonal cues by changing their cellular identities. (shrink)

Automatic Generation Control in modern power systems is getting complex, due to intermittency in the output power of multiple sources along with considerable digressions in the loads and system parameters. To address this problem, this paper proposes an approach to calculate Power System Restoration Indices of a 2-area thermal-hydro restructured power system. This study also highlights the necessary ancillary service requirements for the system under a deregulated environment to cater to large-scale power failures and entire system outages. An abrupt (...) change in consumer load demands and disturbances in any control region of a multiarea system causes severe fluctuations in frequency and interarea power exchanges. However, simple Proportional and Integral controllers are most prevalent in the literature to effectively resolve AGC issues, while its integral gain is smaller due to the larger overshoot in transient performance. Therefore, an attempt has been made with a novel control strategy, known as the pseudoderivative feedforward with feedback controller, is developed to keep the interarea power exchanges and the frequency to the specified limits after load changes. A PDFF controller is designed and implemented using the flower pollination algorithm to obtain optimal dynamic performance for different types of potential power flows in a restructured power system under investigation. The proposed PDFF controller localizes the zero at an optimal place that reduces the rise time of the step-response to reduce the excessive overshoot and gives much better dynamic performances as compared to the PI control structure. The Integral Square Error is considered as a performance criterion to derive the optimized gain of the PDFF control structure using FPA. Different PSRI are computed based on the transient response of the 2-area deregulated multisource system and different restoration measures to be taken are also discussed. The simulation results clearly show that the proposed approach is very powerful in decreasing the frequency and tie-power digressions under different load perturbations. (shrink)

My life as a quantum physicist / M. Nakahara -- A review on operator quantum error correction - Dedicated to Professor Mikio Nakahara on the occasion of his 60th birthday / C.-K. Li, Y.-T. Poon and N.-S. Sze -- Implementing measurement operators in linear optical and solid-state qubits / Y. Ota, S. Ashhab and F. Nori -- Fast and accurate simulation of quantum computing by multi-precision MPS: Recent development / A. Saitoh -- Entanglement properties of a quantum lattice-gas model on (...) square and triangular ladders / S. Tanaka, R. Tamura and H. Katsura -- On signal amplification from weak-value amplification / Y. Shikano -- Topological protection of quantum information / K. Fujii -- Quantum annealing with antiferromagnetic fluctuations for mean-field models / Y. Seki and H. Nishimori -- A method to change phase transition nature - Toward annealing methods / R. Tamura and S. Tanaka -- Computational analysis of the first stage of the photosynthetic system, the light-dependent reaction, by quantum chemical simulation method / M. Tada-Umezaki -- Two-qubit gate operation on selected nearest neighboring qubits in a neutral atom quantum computer / E. Hosseini Lapasar... [et al.] -- A simple operator quantum error correction scheme avoiding fully correlated errors / C. Bagnasco, Y. Kondo and M. Nakahara -- Black hole predictability, classical and quantum / A. Ishibashi -- Classical field simulation of finite-temperature Bose gases / T. Sato -- Atomic quantum simulations of lattice gauge theory: Effect of gauge symmetry breaking / K. Kasamatsu, I. Ichinose and T. Matsui -- Recursive construction of noiseless subsystem for qudits / U. Gungordu... [et al.] -- Composite quantum gates for precise quantum control / M. Bando... [et al.] -- New formulation of statistical mechanics using thermal pure quantum states / S. Sugiura and A. Shimizu -- Thermodynamics in unitary time evolution / T. N. Ikeda -- Second law of thermodynamics with QC-mutual information / T. Sagawa. (shrink)

Tissues are shaped and patterned by mechanical and chemical processes. A key mechanical process is the positioning of the mitotic spindle, which determines the size and location of the daughter cells within the tissue. Recent force and position-fluctuation measurements indicate that pushing forces, mediated by the polymerization of astral microtubules against­ the cell cortex, maintain the mitotic spindle at the cell center in Caenorhabditis elegans embryos. The magnitude of the centering forces suggests that the physical limit on the accuracy and (...) precision of this centering mechanism is determined by the number of pushing microtubules rather than by thermally driven fluctuations. In cells that divide asymmetrically, anti-centering, pulling forces generated by cortically located dyneins, in conjunction with microtubule depolymerization, oppose the pushing forces to drive spindle displacements away from the center. Thus, a balance of centering pushing forces and anti-centering pulling forces localize the mitotic spindles within dividing C. elegans cells. We discuss microtubule-based mechanisms of the mitotic spindle positioning, a key mechanical process that shapes and patterns tissues. The magnitude of the centering forces indicates that the physical limit on the accuracy and precision of centering is set by the number of contributing microtubules rather than by thermally driven fluctuations. (shrink)

Tissues are shaped and patterned by mechanical and chemical processes. A key mechanical process is the positioning of the mitotic spindle, which determines the size and location of the daughter cells within the tissue. Recent force and position-fluctuation measurements indicate that pushing forces, mediated by the polymerization of astral microtubules against­ the cell cortex, maintain the mitotic spindle at the cell center in Caenorhabditis elegans embryos. The magnitude of the centering forces suggests that the physical limit on the accuracy and (...) precision of this centering mechanism is determined by the number of pushing microtubules rather than by thermally driven fluctuations. In cells that divide asymmetrically, anti-centering, pulling forces generated by cortically located dyneins, in conjunction with microtubule depolymerization, oppose the pushing forces to drive spindle displacements away from the center. Thus, a balance of centering pushing forces and anti-centering pulling forces localize the mitotic spindles within dividing C. elegans cells. We discuss microtubule-based mechanisms of the mitotic spindle positioning, a key mechanical process that shapes and patterns tissues. The magnitude of the centering forces indicates that the physical limit on the accuracy and precision of centering is set by the number of contributing microtubules rather than by thermally driven fluctuations. (shrink)

Wavefunction collapse models modify Schrödinger's equation so that it describes the rapid evolution of a superposition of macroscopically distinguishable states to one of them. This provides a phenomenological basis for a physical resolution to the so-called “measurement problem.” Such models have experimentally testable differences from standard quantum theory. The most well developed such model at present is the Continuous Spontaneous Localization (CSL) model in which a universal fluctuating classical field interacts with particles to cause collapse. One “side effect” of this (...) interaction is that the field imparts energy to the particles: experimental evidence on this has led to restrictions on the parameters of the model, suggesting that the coupling of the classical field to the particles must be mass-proportional. Another “side effect” is that the field imparts momentum to particles, causing a small blob of matter to undergo random walk. Here we explore this in order to supply predictions which could be experimentally tested. We examine the translational diffusion of a sphere and a disc, and the rotational diffusion of a disc, according to CSL. For example, we find that the rms distance an isolated 10−5 cm radius sphere diffuses is ≈(its diameter, 5 cm) in (20 sec, a day), and that a disc of radius 2 ⋅ 10−5 cm and thickness 0.5 ⋅ 10−5 cm diffuses through 2πrad in about 70 sec (this assumes the “standard” CSL parameter values). The comparable rms diffusions of standard quantum theory are smaller than these by a factor 10−3±1. It is shown that the CSL diffusion in air at STP is much reduced and, indeed, is swamped by the ordinary Brownian motion. It is also shown that the sphere's diffusion in a thermal radiation bath at room temperature is comparable to the CSL diffusion, but is utterly negligible at liquid He temperature. Thus, in order to observe CSL diffusion, the pressure and temperature must be low. At the low reported pressure of 5 ⋅ 10−17 Torr, achieved at 4.2°K, the mean time between air molecule collisions with the (sphere, disc) is ≈(80, 45)min. This is ample time for observation of the putative CSL diffusion with the standard parameters and, it is pointed out, with any parameters in the range over which the theory may be considered viable. This encourages consideration of how such an experiment may actually be performed, and the paper closes with some thoughts on this subject. (shrink)

Bohr and Heisenberg suggested that the thermodynamical quantities of temperature and energy are complementary in the same way as position and momentum in quantum mechanics. Roughly speaking their idea was that a definite temperature can be attributed to a system only if it is submerged in a heat bath, in which case energy fluctuations are unavoidable. On the other hand, a definite energy can be assigned only to systems in thermal isolation, thus excluding the simultaneous determination of its (...) temperature. Rosenfeld extended this analogy with quantum mechanics and obtained a quantitative uncertainty relation in the form ΔU Δ(1/T) ≥ k, where k is Boltzmann's constant. The two “extreme” cases of this relation would then characterize this complementarity between isolation (U definite) and contact with a heat bath (T definite). Other formulations of the thermodynamical uncertainty relations were proposed by Mandelbrot (1956, 1989), Lindhard (1986), and Lavenda (1987, 1991). This work, however, has not led to a consensus in the literature. It is shown here that the uncertainty relation for temperature and energy in the version of Mandelbrot is indeed exactly analogous to modern formulations of the quantum mechanical uncertainty relations. However, his relation holds only for the canonical distribution, describing a system in contact with a heat bath. There is, therefore, no complementarily between this situation and a thermally isolated system. (shrink)

The blackbody radiation field is studied from different points of view. The existence of zero-point fluctuations is shown to be crucial in determining the form of the thermal part of the spectrum. The notion of a continuous field is seen to be compatible with a discrete structure for its interaction: The description normally used in the quantum context does not refer to the field but to its interaction with atomic systems, which involves statistically independent elementary acts of absorption (...) and emission. The same classical field has different effects on absorption and on emission, and these are conveniently, but not necessarily, described in terms of non-commuting operators. (shrink)

We make a brief review of the Kramers escape rate theory for the probabilistic motion of a particle in a potential well U(x), and under the influence of classical fluctuation forces. The Kramers theory is extended in order to take into account the action of the thermal and zero-point random electromagnetic fields on a charged particle. The result is physically relevant because we get a non-null escape rate over the potential barrier at low temperatures (T → 0). It is (...) found that, even if the mean energy is much smaller than the barrier height, the classical particle can escape from the potential well due to the action of the zero-point fluctuating fields. These stochastic effects can be used to give a classical interpretation to some quantum tunneling phenomena. Relevant experimental data are used to illustrate the theoretical results. (shrink)

This work assembles some basic theoretical elements on thermal equilibrium, stability conditions, and fluctuation theory in self-gravitating systems illustrated with a few examples. Thermodynamics deals with states that have settled down after sufficient time has gone by. Time dependent phenomena are beyond the scope of this paper. While thermodynamics is firmly rooted in statistical physics, equilibrium configurations, stability criteria and the destabilizing effect of fluctuations are all expressed in terms of thermodynamic functions. The work is not a review (...) paper but a pedagogical introduction which may interest theoreticians in astronomy and astrophysicists. It contains sufficient mathematical details for the reader to redo all calculations. References are only to seminal works or readable reviews. Delicate mathematical problems are mentioned but are not discussed in detail. (shrink)

A general framework by which dynamic interactions within a protein will promote the necessary series of structural changes, or “conformational cycle,” required for function is proposed. It is suggested that the free‐energy landscape of a protein is biased toward this conformational cycle. Fluctuations into higher energy, although thermally accessible, conformations drive the conformational cycle forward. The amino acid interaction network is defined as those intraprotein interactions that contribute most to the free‐energy landscape. Some network connections are consistent in every (...) structural state, while others periodically change their interaction strength according to the conformational cycle. It is reviewed here that structural transitions change these periodic network connections, which then predisposes the protein toward the next set of network changes, and hence the next structural change. These concepts are illustrated by recent work on tryptophan synthase. Disruption of these dynamic connections may lead to aberrant protein function and disease states. (shrink)

The effects of the vacuum electromagnetic fluctuations and the radiation reaction fields on the time development of a simple microscopic system are identified using a new mathematical method. This is done by studying a charged mechanical oscillator (frequency Ω 0)within the realm of stochastic electrodynamics, where the vacuum plays the role of an energy reservoir. According to our approach, which may be regarded as a simple mathematical exercise, we show how the oscillator Liouville equation is transformed into a Schrödinger-like (...) stochastic equation with a free parameter h′ with dimensions of action. The role of the physical Planck's constant h is introduced only through the zero-point vacuum electromagnetic fields. The perturbative and the exact solutions of the stochastic Schrödinger-like equation are presented for h′>0. The exact solutions for which h′<h are called sub-Heisenberg states. These nonperturbative solutions appear in the form of Gaussian, non-Heisenberg states for which the initial classical uncertainty relation takes the form 〈(δx 2)〉〈(δp) 2 〉=(h′/2) 2,which includes the limit of zero indeterminacy (h → 0). We show how the radiation reaction and the vacuum fields govern the evolution of these non-Heisenberg states in phase space, guaranteeing their decay to the stationary state with average energy hΩ 0 /2 and 〈(δx) 2 〉〈(δp) 2 〉=h 2 /4 at zero temperature. Environmental and thermal effects-are briefly discussed and the connection with similar works within the realm of quantum electrodynamics is also presented. We suggest some other applications of the classical non-Heisenberg states introduced in this paper and we also indicate experiments which might give concrete evidence of these states. (shrink)

It is demonstrated that Maxwell’s demon can be used to allow a machine to extract energy from a heat bath by use of information that is processed by the demon at a remote location. The model proposed here effectively replaces transmission of energy by transmission of information. For that we use a feedback protocol that enables a net gain by stimulating emission in selected fluctuations around thermal equilibrium. We estimate the down conversion rate and the efficiency of energy (...) extraction from the heat bath. (shrink)

A new event is defined as an intervention in the time reversible dynamical trajectories of particles in a system. New events are then assumed to be quantum fluctuations in the spatial and momentum coordinates, and mental action is assumed to work by ordering such fluctuations. It is shown that when the cumulative values of such fluctuations in a mean free path of a molecule are magnified by molecular interaction at the end of that path, the momentum of (...) a molecule can be changed from its original direction to any other direction. In this way mental action can produce effects through the ordering of thermal motions. Examples are given which show that the ordering of 10^4 10^5 molecules is sufficient to (a) produce detectible PK results and (b) open sufficient ion channels in the brain to initiate a physical action. The relationship of the above model to the arrow of time is discussed. (shrink)

In this paper we explore the possibility of giving a justification of the “semantic information” content and measure, in the framework of the recent coalgebraic approach to quantum systems and quantum computation, extended to QFT systems. In QFT, indeed, any quantum system has to be considered as an “open” system, because it is always interacting with the background fluctuations of the quantum vacuum. Namely, the Hamiltonian in QFT always includes the quantum system and its inseparable thermal bath, formally (...) “entangled” like an algebra with its coalgebra, according to the principle of the “doubling” of the degrees of freedom between them. This is the core of the representation theory of cognitive neuroscience based on QFT. Moreover, in QFT, the probabilities of the quantum states follow a Wigner distribution, based on the notion and measure of quasiprobability, where regions integrated under given expectation values do not represent mutually exclusive states. This means that a computing agent, either natural or artificial, in QFT, against the quantum Turing machine paradigm, is able to change dynamically the representation space of its computations. This depends on the possibility of interpreting QFT system computations within the framework of category theory logic and its principle of duality between opposed categories, such as the algebra and coalgebra categories of QFT. This allows us to justify and not only to suppose, like in the “theory of strong semantic information” of L. Floridi, the definition of modal “local truth” and the notion of semantic information as a measure of it, despite both measures being defined on quasiprobability distributions. (shrink)

Fluctuation phenomena are the ''tip of the iceberg'' revealing the existence, behind even the most quiescent appearing macroscopic states, of an underlying world of agitated, ever-changing microscopic processes. While the presence of these fluctuations can be ignored in some cases, e.g. if one is satisfied with purely thermostatic description of systems in equilibrium, they are central to the understanding of other phenomena, e.g. the nucleation of a new phase following the quenching of a system into the co-existence region. This (...) volume, originally published several years ago, has stood the test of time well, as interest in fluctuation phenomena continues to grow. It contains a collection of review articles, some of them updated, written by experts in the field, on the subject of fluctuation phenomena. Some of the articles are of a very general nature discussing the modern mathematical formulation of the problems involved, while other articles deal with specific topics such as kinetics of phase transitions and conductivity in solids. The juxtaposition of the variety of physical situations in which fluctuation phenomena play an important role is novel and should give the reader a comprehensive and deeper insight into this fascinating subject. (shrink)

In 1916, Einstein rederived the blackbody radiation law of Planck that originated the idea of quantized energy one hundred years ago. For this purpose, Einstein introduced the concept of transition probability, which had a profound influence on the development of quantum theory. In this article, we adopt Einstein's assumptions with two exceptions and seek the statistical condition for the thermal equilibrium of matter without referring to the inner details of either statistical thermodynamics or quantum theory. It is shown that (...) the conditions of thermodynamic equilibrium of electromagnetic radiation and the energy balance of thermal radiation by the matter, between any of its two energy-states, not only result in Planck's radiation law and the Bohr frequency condition, but they remarkably yield the law of the statistical thermal equilibrium of matter: the Maxwell–Boltzmann distribution. Since the transition probabilities of the modern quantum theory of radiation coincide with their definition in Einstein's theory of blackbody radiation, the presented deduction of the Maxwell–Boltzmann distribution is equally valid within the bounds of modern quantum theory. Consequently, within the framework of the fundamental assumptions, the Maxwell–Boltzmann distribution of energy-states is not only a sufficient, but a necessary condition for thermal equilibrium between the matter and radiation. (shrink)

Protein α-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of peptide groups leads to self-trapping of the amide I energy, thereby creating a localized quasiparticle (soliton) that persists at zero temperature. The presence of thermal noise, however, could destabilize the protein soliton and dissipate its energy within a finite lifetime. In this work, we have computationally solved the system of (...) stochastic differential equations that govern the quantum dynamics of protein solitons at physiological temperature, T=310 K, for either a single isolated α-helix spine of hydrogen bonded peptide groups or the full protein α-helix comprised of three parallel α-helix spines. The simulated stochastic dynamics revealed that although the thermal noise is detrimental for the single isolated α-helix spine, the cooperative action of three amide I exciton quanta in the full protein α-helix ensures soliton lifetime of over 30 ps, during which the amide I energy could be transported along the entire extent of an 18-nm-long α-helix. Thus, macromolecular protein complexes, which are built up of protein α-helices could harness soliton-assisted energy transport at physiological temperature. Because the hydrolysis of a single adenosine triphosphate molecule is able to initiate three amide I exciton quanta, it is feasible that multiquantal protein solitons subserve a variety of specialized physiological functions in living systems. (shrink)

Touch is standardly taken to be a proximal sense, principally constituted by capacities to detect proximal pressure and thermal stimulation, and contrasted with the distal senses of vision and audition. It has, however, recently been argued that the scope of touch extends beyond proximal perception; touch can connect us to distal objects. Hence touch generally should be thought of as a connection sense. In this paper, I argue that whereas pressure perception is a connection sense, thermal perception is (...) not. Thermal perception is a proximal sense distinct from touch. One significant consequence of this is that it motivates an alternative explanation of how we detect the thermal properties of the things we touch and what they are. (shrink)

The paper addresses a problem for the unification of quantum physics with the new Aristotelianism: the identification of the members of the category of substance. I outline briefly the role that substance plays in Aristotelian metaphysics, leading to the postulating of the Tiling Constraint. I then turn to the question of which entities in quantum physics can qualify as Aristotelian substances. I offer an answer: the theory of thermal substances, and I construct a fivefold case for thermal substances, (...) based on the irreversibility of time, the definition of thermodynamic concepts, spontaneous symmetry breaking, phase transitions, and chemical form. (shrink)

The two parameters of leaf dimension namely, length and width, show inverse correlation with the third parameter, the thickness. A thermal diffusion model is proposed which explains the inverse relationship between these and envisages that while leaf length and width are directly influenced by the microclimate the thickness is affected by the microclimate through endoclimate and energy balance in the leaves. The significance of the model is discussed in the light of its importance in assessing the survival range of (...) plant species along the altitudinal gradient. (shrink)

Fluctuating asymmetry (FA) is small deviations from perfect symmetry in normally bilaterally symmetrical traits. We examined the relationship between FA of five body traits (ear height, length of three digits, and ankle circumference) and self-reported scores of physical and verbal aggression in a sample of 90 boys aged 10 to 15 years. The relationships between FA and scores of aggression (particularly physical aggression) were found to be negative; in other words, the most symmetrical boys showed highest aggression. One trait (ankle (...) circumference) showed the characteristics of “ideal” FA—parametric mean of zero and a normal distribution. Mean asymmetries calculated from six repeated measures of ankle FA in 30 subjects taken over a period of five months showed strong negative associations with scores of physical aggression which were independent of age, height, and weight.It is argued that soft tissue “cyclical” FA (as opposed to “fixed” bony FA) is dependent on the secretion of hormones: for example, cortisol. Causal associations between behavioral traits such as aggresion and hormones will lead to similar correlations between FA and behavior. (shrink)

Literature shows that psychological phenomena, including values, personality, and behaviors, are geographically clustered. The effects of temperature on interpersonal and intergroup aggression have been studied by many social psychologists. To date the interactions between temperature and other geographical factors have not been addressed. This study is aiming to examine the effects of thermal demands and the moderating effects of natural geographical factors on aggressive behavior at national level. Data for 156 societies was obtained from publicly available databases. Consistent with (...) the life-history theory, results of this study showed that aggressive behavior has a positive relationship with heat demands, and a negative relationship with cold demands. Aggressive behavior is also positively correlated with sunlight and altitude, and negatively correlated with coastline vicinity. Forest, coastline vicinity, and rainfall moderated the effect of thermal demands on aggressive behavior. In societies with more forests, with more rainfall, and closer to coastline, the negative effects of cold demands on aggressive behavior are stronger. (shrink)

A thermal-mechanical analysis of the behavior of the segments of the rollers of the briquetting machines is carried out due to the effect of thermal shock and efforts exerted on the part. It is intended to obtain the main causes that generate this problem, through a mechanical analysis that simulated the behavior in the presence of several thermal gradients. The purpose of the study is to reduce maintenance costs and the continuous replacement and repair of segments, as (...) well as losses in tons of production due to the failure that are of great impact to the industry. This investigation allows us to know to what extent the operating parameters, such as: material temperature, pressure, torque, speed of the rollers influence the life of the segments according to their manufacturing material and based on these the behavior is simulated during the briquetting process. Keywords: Simulation, Finite element, Briquettes. [1]D. F. Pinzón, «Diseño óptimo de Sistemas de Distribución,» Universidad Nacional de Colombia, Bogotá, 2014. [2]F. A. Mendoza Lameda, «Diseño multiobjetivo y multietapa de sistemas de distribución de energía eléctrica aplicando algoritmos evolutivos,» Universidad de Zaragoza, Zaragoza, 2010. [3]L. Miró Hernández y R. Vizcón Toledo, «Sistema Hibrido Propuesto Para la Generación de Electricidad en un Policlínico,» Revista Avanzada Científica, vol. 9, nº 2, pp. 50-56, 2006. [4]J. Lagunas M., C. Ortega S. y P. Caratozzolo M., «Control supervisorio para sistemas híbridos de geración eléctrica basado en lógica difusa,» Boletin UE, Monterrey, 2005. [5]J. L. Bernal Agustín, «Aplicación de algoritmos genéticos al diseño óptimo de sistemas de distribución de energía eléctrica,» Universidad de Zaragoza, Zaragoza, 1998. [6]V. MIranda, J. V. Ranito y L. Proenca, «Genetic Algorithms in Optimal Multistage Distribution Network Planning, » IEEE, Porto, 1994. [7]I. Ramirez-Rosado y J. Dominguez-Navarro, «Computer Aided Desing of Power Distribution Systems: Multiobjective Mathematical Simulations» International Journal of Power and Energy Systems, vol. 19, nº 4, pp. 1801-1810, 2004. (shrink)

I now understand why the invitation to contribute an article on “chaos theory” invoked both my excitement and reticience. Let me first explain my excitement in terms of intriguing developments generated by the Cosmic Background Explorer satellite. Since COBE strengthened an “inflationary” Big Bang Theory wherein the structure of the universe was induced by random statistical fluctuations, there are implications inter alia of thermodynamics for chaotic fluctuations in both the structure and biological systems formed from it. I shall (...) then explain my reticence concerning a chaosladen cosmology. Though it seems to call for an epistemological revision of deterministic scientific truth, the cosmology is as likely as one influenced by quantum mechanics to lead to either a pseudo-scientific connection of indeterminism to freedom and purpose or their dogmatic exclusion as possible “realities” by the natural and social sciences. What I will be concerned about are the conflation of physics with metaphysics and the need to metaphysically articulate the continuity between a primordial quantum fluctuation, biological “possibilities,” and human freedom. (shrink)

Fluctuations in attentional state and their relation to goal neglect were examined in the current study. Participants performed a variant of the Stroop task in which attentional state ratings were given prior to each trial. It was found that pre-trial attentional state ratings predicted subsequent trial performance, such that when participants rated their current attentional state as highly focused on the current task, performance tended to be high compared to when participants reported their current attentional state as being unfocused (...) on the current task. This effect was larger for incongruent than congruent trials leading to differences in the magnitude of the Stroop effect as a function of pre-trial attentional state. Furthermore, variability in attentional state was correlated with overall levels of performance, and when attentional state was covaried out, the Stroop effect was greatly reduced. These results suggest a link between fluctuations in pre-trial attentional state and goal neglect. (shrink)

Fluctuating asymmetry is more a signal of genetic fitness than a marker observable only to the researcher. Hence, it has to be demonstrated that low FA is an honest signal of genetic quality; this has not been demonstrated in Gangestad & Simpson's otherwise useful review.

Macroeconomic fluctuations in interest rates, exchange rates, and inflation can be considered sources of good or bad “luck” for corporate performance if management is unable to adjust operations to these fluctuations. Based on a sample of 2,091 US firms, we decompose the impacts of macroeconomic fluctuations on three measures of CEO compensation. Our study provides empirical support for the importance of considering macroeconomic fluctuations in designing CEO incentive schemes. It adds to the managerial power literature on (...) moral hazard and CEO compensation by pinpointing the obvious risk that the CEO in an asymmetric and non-linear reward system will be inclined to prioritize his/her own cash flow at the expense of fulfilling an assumed agency role. The policy conclusion for remuneration committees and board of directors is to filter out macroeconomic influences on performance to be rewarded whenever an asymmetric compensation scheme has been opted for. (shrink)

The distribution function associated with a classical gas at equilibrium is considered. We prove that apart from a factorisable multiplier, the distribution function is fully determined by the correlations among local momenta fluctuations. Using this result we discuss the conditions which enable idealised local observers, who are immersed in the gas and form a part of it, to determine the distribution 'from within'. This analysis sheds light on two views on thermodynamic equilibrium, the 'ergodic' and the 'thermodynamic limit' schools, (...) and the relations between them. It also provides an outline for a new definition of equilibrium that is weaker than full ergodicity. Finally, we briefly discuss the possibility that the distribution can be determined by external observers. (shrink)

The theoretical principles and methodological aspects of the thermal field-flow fractionation applied to study the thermal diffusion of the macromolecules in solution and colloidal particles in suspension were developed. The theoretical analysis indicated that the miniaturization of the separation channel for thermal field-flow fractionation should improve the performance of this technique. A new microchannel was conceived and built. The experimental results obtained for polymer samples with an extended range of molar masses from relatively low up to ultrahigh (...) and for the colloidal particles confirmed that the achieved resolution is the same but the versatility of the microchannel is superior to that of the standard size channels owing to the substantial decrease in the heat energy flux. This important improvement allows us to achieve very high resolution when applying constant-field-force operation, it makes it much easier to program the temperature drop which is an advantageous operational mode from the viewpoint of the time of analysis, and it extends considerably the range of perfectly controlled temperatures of the cold and hot walls. The sample amount needed for one analysis can be as small as a few nanograms. (shrink)

This paper explores a variety of perfect being theism that combines Yujin Nagasawa’s maximal God thesis with the view that God is not atemporal. We argue that the original maximal God thesis still implicitly relies on a “static” view of divine perfections. Instead, following the recent re-evaluation of divine immutability by analytic philosophers, we propose that thinking of divine great-making properties as fluctuating but nevertheless remaining maximal either for every time t or across all times strengthens the original maximal God (...) thesis. Furthermore, we show that “temporalising” Nagasawa’s maximal God and adopting what we call the fluctuating maximal God thesis provides more effective ways of responding to objections to perfect being theism, in particular, the argument from evil and some conceptual problems pertaining to the Incarnation. Finally, we demonstrate that our proposal is compatible with Christian Scriptures and coheres with numerous biblical passages better than Nagasawa’s original proposal does. (shrink)

Albania is part of the emerging economies of the Western Balkan region. Polis University is one of the pioneering institutions in the field of architecture, built environment, and city sciences that represents innovative methodologies and concepts for educational and scientific purposes. Nowadays, many constructions in Albania involve a wide range of different materials. The building envelope is one of the main elements that provide protection from the outside environment but also the required thermal comfort for the inhabitants. The necessary (...) balance must be archived between energy efficiency and the durability of buildings. This paper will focus on the thermal performance and materials composition of two different types of masonry walls, a constituent part of Polis University's main building. The study will be based on an experiment using specific instruments to diagnose these typologies of wall composition. The results are further analyzed and compared. Specific instruments such as the thermal camera (Testo 882), U-value(Testo 435-2), and “Silverline Digital Moisture Meter” (from POLIS Energy lab) are engaged. The collected data are further interpreted through graphs, tables, and diagrams for both cases. It is observed that ventilated facades perform much better than standard facades, therefore their usage is strongly recommended. (shrink)

We consider an isolated, macroscopic quantum system. Let H be a microcanonical “energy shell,” i.e., a subspace of the system’s Hilbert space spanned by the (finitely) many energy eigenstates with energies between E and E + δE. The thermal equilibrium macro-state at energy E corresponds to a subspace Heq of H such that dim Heq/ dim H is close to 1. We say that a system with state vector ψ H is in thermal equilibrium if ψ is “close” (...) to Heq. We show that for “typical” Hamiltonians with given eigenvalues, all initial state vectors ψ0 evolve in such a way that ψt is in thermal equilibrium for most times t. This result is closely related to von Neumann’s quantum ergodic theorem of 1929. (shrink)