Working memory (WM) is a fundamental cognitive ability to support complex thought, but it is limited in capacity. WM training has shown the potential to make benefit for those in need. Many studies have shown the potential of transcranial direct current stimulation (tDCS) to transiently enhance WM performance by delivering low current to the brain cortex of interest via electrodes on the scalp. TDCS has also been revealed as a promising intervention to augment WM training in a few studies. However, (...) those few tDCS-paired WM training studies focused more on the effect of tDCS on WM enhancement and its transferability after training but paid less attention to the variation of cognitive performance during the training procedure. The current study attempted to explore the effect of tDCS on the variation of performance during WM training in healthy young adults. All the participant received WM training with the load-adaptive verbal N-back task for five days. During the training procedure, active/sham anodal high-definition tDCS (HD-tDCS) was used to stimulate the left dorsolateral prefrontal cortex (DLPFC). To examine the training effect, pre- and post-test were performed respectively one-day before and after the training sessions respectively. At the beginning of each training session, stable-load WM tasks were performed to examine the performance variation during training. Compared to the sham stimulation, higher learning rates of performance metrics during the training procedure were found when WM training was combined with active anodal HD-tDCS. The performance improvements (post-pre) of the active group were also found to be higher than those of sham group and were transferred to a similar untrained WM task. Further analysis revealed that the negative relation between the training improvements and baseline performance. These findings show the potential that tDCS may be leveraged as an intervention to facilitate WM training for those in need of higher WM ability. (shrink)

In order to discover the justice and argue that it is a goodness, Socrates draws an analogy between the justice of a polis and the justice of an individual in the book II of the Republic. According to him, a polis is a large version of an individual. In Book IV, Socrates proves their congruity from two perspectives --- the polis and the soul are the same “tripartite”: Both of them have the same four virtues. He thus explains why the (...) vulgar justice is good, and makes a preliminary definition of the nature of justice as well. In his view, the justice is doing one’s own; therefore like temperance, it runs through all the notes of the scale and brings both the polis and the soul harmony and symphony. Seen in the context of the Republic as a whole, this argument of Socrates’ is obviously not convincing. Readers are reasonable in raising the following questions: First, are a polis and an individual of the same composition? Second, are virtues of the state necessarily virtues of the soul? In other words, must a good man be a good citizen? This paper is to deal with Socrates’ argument from these two aspects. In fact, a polis cannot achieve the same harmony and symphony as an individual, nor can political virtues come to the same level as philosophical ones. Hence, a good citizen is not necessarily a good man. Rather, the justice of polis is more of temperance while the justice of soul is more of wisdom. If it is true that the genuine virtue is knowledge, therefore only philosophers are the most just and happiest in the world, then more thought needs to be given to the view that the vulgar virtuesinevitably mean happiness. (shrink)

Traditional spatial enabled grammars lack flexibility in specifying the spatial semantics of graphs. This paper describes a new graph grammar formalism called the multigranularity Coordinate Graph Grammar (mgCGG) for spatial graphs. Based on the Coordinate Graph Grammar (CGG), the mgCGG divides coordinates into two categories, physical coordinates and grammatical coordinates, where physical coordinates are the common coordinates in the real world, and grammatical coordinates describe the restrictions on the spatial semantics. In the derivation and reduction of the mgCGG, the spatial (...) matching conditions between nodes are evaluated on the basis of the grammatical coordinates, which can be obtained by the specified granularities. By adjusting the granularities, both qualitative and quantitative analyses for spatial semantics can be obtained, including the transition states between them. In addition, a new redex searching algorithm with polynomial time complexity is designed for the mgCGG. A running example of drawing a flowchart is given to illustrate a practical application of the mgCGG. Through a detailed comparison with related spatial-enabled grammars, it is found that the mgCGG has good performance in four critical aspects—the semantics processing mechanism, fault-tolerance, redex searching algorithm, and practical application—providing a flexible yet uniform way to specify spatial graphs and building a bridge between nonspatial and spatial grammars. (shrink)

本书紧扣三木哲学的现实性和时代性特质,以昭和前半期的主要思潮为主线剖析三木清的哲学的形成和发展.

In vitro reconstitution assays are commonly used to study biological membrane fusion. However, to date, most ensemble and single‐vesicle experiments involving SNARE proteins have been performed only with lipid‐mixing, but not content‐mixing indicators. Through simultaneous detection of lipid and small content‐mixing indicators, we found that lipid mixing often occurs seconds prior to content mixing, or without any content mixing at all, during a 50‐seconds observation period, for Ca2+‐triggered fusion with SNAREs, full‐length synaptotagmin‐1, and complexin. Our results illustrate the caveats of (...) commonly used bulk lipid‐mixing fusion experiments. We recommend that proteoliposome fusion experiments should always employ content‐mixing indicators in addition to, or in place of, lipid‐mixing indicators. (shrink)

Teaching research activities in China are practical and reflective research of teachers on teaching. These required activities are meant to ensure quality education and facilitate the professional development of teachers. However, in TRA, teachers encounter many challenges such as low efficiency and weak team collaboration. These problems make it hard to achieve the expected outcomes. W Primary School reformed its activities using Change Laboratory, a formative intervention approach to workplace learning and development based on activity theory. The data collected included (...) seven recorded meetings in the Change Laboratory. The conversations in the meetings were then transcribed into texts. A deductive method of content analysis was used to code the data, focusing on categorizing comments of teachers about the transformative agency. The findings showed the following: There were five types of transformative agencies, namely, resisting, criticizing, explicating, envisioning, and committing to actions. Resisting and criticizing were represented less frequently, and taking action did not emerge as a type of transformative agency. The comments about transformative agency about tools were more frequent than comments about other elements in the activity system. There were some differences in the expression of transformative agency across participants. At the end of this study, the implications for the development of TRA are discussed. (shrink)

本书通过对庄子生存哲学的人生、生死、语言、天人、宇宙、科技、生态、思维等向度的深入考察来反思传统、拷问现在、探寻未来。.

With the innovation of computer, virtual clothing has also emerged. This research mainly discusses the real-time animation complex of interactive clothing design based on computer simulation. In the process of realizing virtual clothing, the sample interpolation synthesis method is used, and the human body sample library is constructed using the above two methods first, and then, the human body model is obtained by interpolation calculation according to the personalized parameters. Building a clothing model is particularly important for the effect of (...) trying on. The clothing that needs to be displayed can be scanned and then input into the computer to build the model. The model can be directly built in 3DMAX and other software and then its surface texture can be mapped, or the clothing model can be directly built. The 3D model in the 3ds file is loaded by the loop body nested switch branch selection structure. Correspondingly, the write-back operation of 3ds files is similar. Just follow the general structure of the 3ds file and write the root block, version information block, edit information block, key frame information block, etc. to a brand new file in sequence. The main reason for this article to perform the 3ds file write-back operation is that, after the clothing model is dynamically simulated through the dynamic principle, the deformed key animation frame needs to be saved as a 3ds file so that it can be further imported into the 3DSMAX software and generated by the renderer, form high-quality picture information, and finally get high-definition animation video. In the CPU-GPU hybrid method, modules such as force calculation, collision processing, and position update use the GPU method, while overstretching is processed by the CPU method, making the overall performance 10 times higher than the pure CPU method. This research helps to promote the development of 3D virtual clothing design. (shrink)

BackgroundTemporal interference (TI) stimulation is a novel technique that enables the non-invasive modulation of deep brain regions. However, the implementation of this technology in humans has not been well-characterized or examined, including its safety and feasibility.ObjectiveWe aimed to examine the feasibility, safety, and blinding of using TI on human participants in this pilot study.Materials and methodsIn a randomized, single-blinded, and sham-controlled pilot study, healthy young participants were randomly divided into four groups [TI and transcranial alternating current stimulation (tACS) targeting the (...) right frontoparietal region, TI-sham, and tACS-sham]. Each participant was asked to complete N-back (N = 1 to 3) tasks before, during, and after one session of stimulation to assess their working memory (WM). The side effects and blinding efficacy were carefully assessed. The accuracy, reaction time (RT), and inverse efficiency score (IES, reaction time/accuracy) of the N-back tasks were measured.ResultsNo severe side effects were reported. Only mild-to-moderate side effects were observed in those who received TI, which was similar to those observed in participants receiving tACS. The blinding efficacy was excellent, and there was no correlation between the severity of the reported side effects and the predicted type of stimulation that the participants received. WM appeared to be only marginally improved by TI compared to tACS-sham, and this improvement was only observed under high-load cognitive tasks. WM seemed to have improved a little in the TI-sham group. However, it was not observed significant differences between TI and TI-sham or TI and tACS in all N-back tests.ConclusionOur pilot study suggests that TI is a promising technique that can be safely implemented in human participants. Studies are warranted to confirm the findings of this study and to further examine the effects of TI-sham stimulation as well as the effects of TI on deeper brain regions. (shrink)

With the development of China’s higher education, China has become increasingly popular as an education destination for international students. To explore the rationale and the influencing factors for them to attend Chinese universities, this research adopted a questionnaire survey and interviews with international students from a top university in China. The data were analyzed from four aspects: home countries’ push factors, China’s pull factors, university attractiveness factors and personal choice factors. The findings show that university attractiveness factors are more significant (...) than the China’s pull factors and the home countries push factors; China’s pull factors have significant influence on the university attractiveness factors; For students from different regions, the factors of China’s pull, home country’s push and university attractiveness play significantly different role in affecting their choice of university, with Asian students much more affected than those from other parts of the world. Besides, individual subjective norms and individual value choices also affect students’ choices to study abroad. (shrink)

At present, although artificial intelligence (AI) has made great progress in the aspects of control policy and operation, there is still no unified ethical decision mode, laws and regulations in ethical dilemma, which seriously affect application and development of artificial intelligence. Therefore, this paper studies and analyzes various ethical decision mode of AI system, then the current research status and advantages, deficiencies of these decision modes are analyzed and summarized. According to the characteristics of the current ethical decision modes and (...) existing problems, the future implementation mode for the future ethical decision of artificial intelligence is explored and discussed. A hierarchical hybrid ethical decision mode will be proposed and designed, which has the advantages of the existing ethical decision modes. In addition, it will provide a few references for research, design and formulation of laws, regulations of AI. (shrink)

To construct fractional rogue waves, this paper first introduces a conformable fractional partial derivative. Based on the conformable fractional partial derivative and its properties, a fractional Schrödinger equation with Lax integrability is then derived and first- and second-order fractional rogue wave solutions of which are finally obtained. The obtained fractional rogue wave solutions possess translational coordination, providing, to some extent, the degree of freedom to adjust the position of the rogue waves on the coordinate plane. It is shown that the (...) obtained first- and second-order fractional rogue wave solutions are steeper than those of the corresponding NLS equation with integer-order derivatives. Besides, the time the second-order fractional rogue wave solution undergoes from the beginning to the end is also short. As for asymmetric fractional rogue waves with different backgrounds and amplitudes, this paper puts forward a way to construct them by modifying the obtained first- and second-order fractional rogue wave solutions. (shrink)

We here review primary methods used in quantifying and mapping 5‐hydroxymethylcytosine (5hmC), including global quantification, restriction enzyme‐based detection, and methods involving DNA‐enrichment strategies and the genome‐wide sequencing of 5hmC. As discovered in the mammalian genome in 2009, 5hmC, oxidized from 5‐methylcytosine (5mC) by ten‐eleven translocation (TET) dioxygenases, is increasingly being recognized as a biomarker in biological processes from development to pathogenesis, as its various detection methods have shown. We focus in particular on an ultrasensitive single‐molecule imaging technique that can detect (...) and quantify 5hmC from trace samples and thus offer information regarding the distance‐based relationship between 5hmC and 5mC when used in combination with fluorescence resonance energy transfer. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Narrative Symposium:Conflicting Interests in MedicineLaura Jean Bierut, Sal Cruz-Flores, Laura E. Hodges, Anthony A. Mikulec, Govind K. Nagaldinne, Erine L. Bakanas, John F. Peppin, Joel S. Perlmutter, William H. Seitz Jr., Edward Diao, Andre N. Sofair, and David M. Zientek• To Recruit or Not to Recruit for a Clinical Trial• An Unexpected Lesson• Am I on call for the entire Midwest?• Why is Medicare Wasting Away?• The Downside (...) of the Informed Consent Juggernaut• Expert Testimony at the Food and Drug Administration: Who Wants the Truth?• Crossroads: The Intersection of Personal, Professional Society, and Industry Relationships• A Change of Heart• The Evolution of Conflicts of Interest in a New Subspecialty: A Case Study of the Development of Interventional CardiologyCopyright © 2011 The Johns Hopkins University Press... (shrink)

Aerial work platform is a kind of engineering vehicle which is used for hoisting personnel to the appointed place for maintenance or installation. Based on the dynamics model considering the flexible deformation existing in the arm system of folding-boom aerial platform vehicle, this study presents a NN-based backstepping controller used for trajectory tracking control of work platform. The proposed controller can reduce tracking error of work platform and suppress the vibration simultaneously by using the RBF neural network system to compensate (...) model uncertainties and disturbances. Furthermore, we prove that the whole system is stable and convergent by Lyapunov stability theorem. In addition, we give the simulation results which show that the good control performance of the designed controller for trajectory tracking and vibration inhabiting of work platform in the case of model uncertainties. (shrink)

Collaborative research practices in the field of plant genetic resources must follow the principles of fairness and equity as defined in the Convention on Biological Diversity (CBD) and in the International Treaty on Plant Genetic Resources for Food and Agriculture (ITPGRFA). In this context the concepts of fairness and equity generally refer to the substantive and procedural dimensions associated with sharing the benefits of this research. But neither term is clearly defined by these international treaties, and the meanings attributed to (...) the concepts vary among different societies. This paper looks at the question of how to account for the diversity among value systems when conducting research that implicates diverse stakeholders and respects the requirements of fairness and equity. We incorporated an auto-ethnography method developed as part of a multi-stakeholder network involved in research projects on plant genetic resources in West Africa. A theatrical device was used as a framework for testing the principles of fairness and equity, helping us to collectively identify feelings of injustice, and explore the conditions for making collaborative research practices more ethical in ways that respect the perspectives of different stakeholders. In an environment of extensive political and socio-cognitive inequality, this approach makes it possible to explain the criteria relating to interactional justice and expectations in terms of socio-political and socio-emotional benefits. It also invites us to consider the principles of fairness and equity in a framework of ethical competence that goes beyond international directives. (shrink)

BackgroundProfessional ethics is the regulation and discipline of nurses’ daily nursing work. Nurses often encounter various ethical challenges and problems in their clinical work, but there are fe...

Numerous studies had found that creativity is not only associated with low effort and flexible processes, but also associated with high effort and persistent processes especially when defensive behavior being induced negative emotions. The important role of self-esteem is to buffer the negative emotions and low self-esteem are prone to instigate various forms of defensive behaviors. Thus, we thought that the relationships between trait creativity and executive control brain networks might be modulated by self-esteem. The resting-state electroencephalogram (RS-EEG) microstates can (...) divided into four classical types (MS1, MS2, MS3 and MS4) which can reflect the brain networks as well as the dynamic characteristic of them. Thus, Williams creative tendency scale (WCTS) and Rosenberg Self-Esteem Scale (RSES) were used to investigate the modulating role of self-esteem on the relationships between trait creativity and the RS-EEG microstates. As our results showed, self-esteem consistently modulated the relationships between creativity and the duration and contribution of MS2 related to visual or imagery processing, the occurrence of MS3 related to cingulo-opercular networks, as well as transitions between MS2 and MS4 which was related to frontoparietal control networks. Based on these results, we thought that Moreover, individuals with low self-esteem might be more prone to influenced by negative emotions and develop low trait creativity; bottom-up information from vision or visual imagery might be beneficial to develop trait creativity for individuals with high self-esteem to improve trait creativity, while inhibition of irrelevant information could facilitate trait creativity for individuals with low self-esteem. (shrink)

The quality of Innovation and Entrepreneurship Education in higher institutions is closely related to the degree to which the undergraduates absorb relevant innovation and entrepreneurship knowledge and their entrepreneurial motivation. Thus, an effective Evaluation of Educational Quality is essential. In particular, fault tree analysis, a common EEQ approach, has some disadvantages, such as fault data reliance and insufficient uncertainties handleability. Thereupon, this article first puts forward a theoretical model based on the deep learning method to analyze the factors of IEE (...) quality; consequently, based on the traditional FTA, fuzzy fault tree analysis is proposed to evaluate the reliability of IEE classroom teaching for college teachers and students. Finally, based on the top event of entrepreneurial teaching failure, the hyper-ellipsoid model is implemented to restrict the interval probability of basic events and describe the deviation of uncertain events. Furthermore, the model accuracy is verified by a questionnaire survey, based upon which the factors of IEE quality are analyzed. The results show that the designed QS has good reliability, validity, and fitness; the path coefficients of cooperative ability to critical thinking and innovative thinking are 0.9 and 0.66, respectively, indicating that the students’ cooperative ability plays a vital role in the classroom teaching. By calculation, the probability of “teaching failure” in entrepreneurial classroom teaching is 0.395, 3, 0.462, and 5. To sum up, the proposed method can effectively and quantitatively evaluate the quality of IEE in higher institutions, thus providing a certain basis for formulating relevant improvement strategies. The purpose is to provide important technical support for improving the IEE quality. (shrink)

The prevalence of mobile phone addiction has increased rapidly in recent years, and it has had a certain negative impact on emotions and cognitive capacities. At the level of neural circuits, the continued increase in activity in the brain regions associated with addiction leads to neural adaptations and structural changes. At present, the spontaneous brain microstates that could be negatively influenced by MPA are unclear. In this study, the temporal characteristics of four resting-state electroencephalogram microstates related to mobile phone addiction (...) tendency were investigated using the Mobile Phone Addiction Tendency Scale. We attempted to analyze the correlation between MPAT and corresponding microstates and provide evidence to explain the brain and behavioral changes caused by MPA. The results showed that the total score of the MPATS was positively correlated with the duration of MS1, related to phonological processing and negatively correlated with the duration of MS2, related to visual or imagery processing, and MS4, related to the attentional network; the score of the withdrawal symptoms subscale was additionally associated with duration of MS3, related to the cingulo-opercular emotional network. Based on these results, we believe that MPAT may have some negative effects on attentional networks and sensory brain networks; moreover, withdrawal symptoms may induce some negative emotions. (shrink)

Several recent studies have found that when the other’s gain is greater, even subjects’ reward may seem like a loss and lead to a negative experience. These studies indicate the complexity of reward evaluation in the context of social comparison. The satisfaction rating of reward outcome not only depends on objective social comparison but also on subjective evaluation. However, less is known about the neural time course of subjective evaluation. Therefore, we employed a 2 × 2 within-subjects factorial design, in (...) which we manipulated the reward distribution for the subjects. Electroencephalography responses were recorded, while two subjects concurrently but independently performed a simple dot-estimation task that entailed monetary rewards. Behavioral results showed that the subjects were more satisfied with the advantageous distribution, regardless of upward or downward comparison. The analysis of event-related potentials revealed that disadvantageous distribution elicited a larger P2 than advantageous distribution, and this effect was not modulated by comparison direction. In contrast, the late positive potential showed an effect of comparison direction independent of subjective evaluation. The data suggest that subjective evaluation acts upon the early stage of reward processing and manifests in the P2 component, whereas social comparison plays a role in the later appraisal process. (shrink)

At present, most of the research in the field of medical-assisted diagnosis is carried out based on image or electronic medical records. Although there is some research foundation, they lack the comprehensive consideration of comprehensive image and text modes. Based on this situation, this article proposes a fusion classification auxiliary diagnosis model based on GoogleNet model and Bi-LSTM model, uses GoogleNet to process brain computed tomographic images of ischemic stroke patients and extract CT image features, uses Bi-LSTM model to extract (...) the electronic medical record text, integrates the two features using the full connection layer network and Softmax classifier, and obtains a method that can assist the diagnosis from two modes. Experiments show that the proposed scheme on average improves 3.05% in accuracy compared to individual image or text modes, and the best performing GoogleNet + Bi-LSTM model achieves 96.61% accuracy; although slightly less in recall, it performs better on F1 values, and has provided feasible new ideas and new methods for research in the field of multi-model medical-assisted diagnosis. (shrink)

Previous studies have explored the impact of the cost ratio of individual solutions versus collective solutions on people’s cooperation tendency in the presence of individual solutions. This study further explored the impact of team credibility on people’s propensity to cooperate in the presence of individual solutions. Study 1 investigated the influence of different level of altruistic tendencies or the self-interest tendencies of teammates on participants’ decision-making. Study 2 explored the influence of the distribution of altruistic tendencies or self-interest tendencies on (...) participants’ decision-making. The results of Study 1 showed that the proportion of participants who chose the collective solution increased with an increase in the altruistic tendencies of the team. When the altruistic tendencies of the teammates reached a certain value, the proportion of participants taking the collective solution showed a trend to stabilize. Furthermore, the proportion of participants who chose the individual solution increased with the increase in the self-interest tendencies of the team. When the self-interest tendencies of the teammates reached a certain value, the individual solution was stably adopted. The results of Study 2 showed that with the total altruistic tendency remaining unchanged, the more altruistic group members that altruistic tendencies were allocated to, the higher a participant’s level of trust in the team would be, which showed the decentralized effect of altruistic tendencies. In the case that the total self-interest tendency was unchanged, the fewer self-interest group members the self-interest tendencies were allocated to, the higher a participant’s level of trust in the team would be, which showed the convergent effect of self-interest tendencies. (shrink)

本书收录了“说出你的权利”、“被遗忘的和被轻侮的”、“理性与宽容”、“民主的后援力量”等文集。.

本书共分十五章,内容包括:证据制度的历史沿革,证据资格和证据分类,证据的法定形式类,司法证明的标准与方法,司法证明的对象与责任,证据调查的主体等.