An emerging concept is that quiescent mature skeletal cells provide an important cellular source for bone regeneration. It has long been considered that a small number of resident skeletal stem cells are solely responsible for the remarkable regenerative capacity of adult bones. However, recent in vivo lineage‐tracing studies suggest that all stages of skeletal lineage cells, including dormant pre‐adipocyte‐like stromal cells in the marrow, osteoblast precursor cells on the bone surface and other stem and progenitor cells, are concomitantly recruited to (...) the injury site and collectively participate in regeneration of the damaged skeletal structure. Lineage plasticity appears to play an important role in this process, by which mature skeletal cells can transform their identities into skeletal stem cell‐like cells in response to injury. These highly malleable, long‐living mature skeletal cells, readily available throughout postnatal life, might represent an ideal cellular resource that can be exploited for regenerative medicine. (shrink)

This article develops an axiom system to justify an additive representation for a preference relation ${\succsim}$ on the product ${\prod_{i=1}^{n}A_{i}}$ of extensive structures. The axiom system is basically similar to the n-component (n ≥ 3) additive conjoint structure, but the independence axiom is weakened in the system. That is, the axiom exclusively requires the independence of the order for each of single factors from fixed levels of the other factors. The introduction of a concatenation operation on each factor A i (...) makes it possible to yield a special type of restricted solvability, i.e., additive solvability and the usual cancellation on ${\prod_{i=1}^{n}A_{i}}$ . In addition, the assumption of continuity and completeness for A i implies a stronger type of solvability on A i . The additive solvability, cancellation, and stronger solvability axioms allow the weakened independence to be effective enough in constructing the additive representation. (shrink)

The project of the comprehensive reform of Japanese insolvency law started in October 1996. After many enactments and amendments, there are now two types of judicial proceedings for personal insolvencies in Japanese insolvency law. The first category is straight bankruptcy proceedings in which the debtor can be discharged; the other is special Civil Rehabilitation proceedings for individual debtors. In this Article, I will first give a brief overview of the special Civil Rehabilitation proceedings for individual debtors, including a short description (...) of two types of proceedings, and legislative issues. Then I will give a brief overview of major amendments of the Bankruptcy Law concerning individual bankruptcies, including amendments relating to the scope of exemption and discharge proceedings. (shrink)

Endosteal stem cells are a subclass of bone marrow skeletal stem cell populations that are particularly important for rapid bone formation occurring in growth and regeneration. These stem cells are strategically located near the bone surface in a specialized microenvironment of the endosteal niche. These stem cells are abundant in young stages but eventually depleted and replaced by other stem cell types residing in a non‐endosteal perisinusoidal niche. Single‐cell molecular profiling and in vivo cell lineage analyses play key roles in (...) discovering endosteal stem cells. Importantly, endosteal stem cells can transform into bone tumor‐making cells when deleterious mutations occur in tumor suppressor genes. The emerging hypothesis is that osteoblast‐chondrocyte transitional identities confer a special subset of endosteal stromal cells with stem cell‐like properties, which may make them susceptible for tumorigenic transformation. Endosteal stem cells are likely to represent an important therapeutic target of bone diseases caused by aberrant bone formation. (shrink)

Senshu University has hosted many international conferences on medieval English literature - primarily on Geoffrey Chaucer and William Langland - as well as in the related fields of Old Germanic, medieval French and Renaissance Italian literature. These international collaborations inform and contribute to the present volume, which addresses the heritage bequeathed to medieval English language and literature by the classical world.<BR> This volume explores the development of medieval English literature in light of contact with Germanic and Old Norse cultures, on (...) the one hand, and Romance languages, on the other. The book includes a comparative study of <I>Beowulf in the Germanic context, discusses aspects of <I>Piers Plowman and its tradition, and offers philological approaches to Chaucer (especially his <I>Troilus and Criseyde). The articles assembled here collectively suggest how the torches of classical learning were carried from continental Europe to illuminate the pages of medieval English literature. (shrink)

松下幸之助是日本著名的企业家,他除了出色地进行经营管理之外,还在晚年以谈话录的形式,对人生的各种问题进行了总结。本书是从他的谈话集中精选的,涉及到奠定人生大厦的基石、智慧的思考、处理人际关系、不怕挫折 、领导艺术等多方面的内容。.

Although modern education is expected to solve social problems, it has brought about new problems. While theoretical critiques of education have not always been successful, with the transition to a data-driven society, education as a historical product is actually losing its efficacy. However, this does not mean that acquisition of knowledge and skills is becoming unnecessary. Prompted by the need to change the purpose of public education, we are forced to rethink the nature of education boldly. Competency-based education, as advocated (...) by the OECD, appears to have led to such rethinking; however, it is widely accepted as a revised version of modern education. If this trend continues, the contradiction between education and society will deepen further. To overcome this contradiction, we must change our view of education. With education and learning having an asymmetrical relationship to begin with, the clue to changing our view of education lies in re-examining our view of learning. A more comprehensive way of learning that has accompanied human history is attracting the attention of various disciplines. I present a redefined framework for learning that is inherent to humans, which I call the ecological view of learning, and explore an alternative to modern education, learning from the Japanese thought on ‘Manabi (learning).’. (shrink)

Background: Long working hours and mental health problems among teachers are a concern in Japan. More specifically, it has been reported that junior high school teachers tend to work overtime. In this study, examined the working hours of junior high school teachers in public schools and investigated the association between overtime work and stress responses across job titles.Methods: From June to December 2018, 54,772 teachers in public junior high schools completed a web-based nationwide survey regarding occupational stress and submitted self-evaluated (...) working hours per day of the previous month. Psychological and physical stress responses were assessed using the Brief Job Stress Questionnaire.Results: Results showed that 59.6% of the participants worked 11 h or more per day. Additionally, the length of working hours significantly differed across job titles = 5295.8, p < 0.001, Cramér’s V = 0.14). With respect to tenured teachers, sex, age, taking charge of the class, number of working years in the same school, working hours of 10 to 11 h, 11 to 12 h, 12 to 13 h, and 13 h or more were significantly associated with high stress, compared to those who worked less than 9 h per day. Moreover, for fixed-term teachers, sex, age, working hours of 9 to 10 h, 10 to 11 h, 11 to 12 h, 12 to 13 h, and 13 h or more were related with more stress as compared to those who worked less than 9 h per day. On the other hand, there was no significant relationship between long working hours and stress response among vice-principals, even though they tended to work the longest hours.Conclusion: We verified that Japanese junior high school teachers work long hours. Long working hours were associated with stress responses in both tenured and fixed-term teachers, but not in vice-principals. However, vice-principals work the longest hours among teachers, and we suggest that these long working hours may be a hidden problem that is often overlooked. (shrink)

Under the presupposition that human time perception is distorted in intertemporal choice, this study constructs a time scale in the framework of axiomatic measurement. First, the conditions (homogeneity of degree one or two) to identify the form of a time scale are proposed so that one can determine whether the hyperbolic or exponential is a more suitable function for modeling people’s discounting. Homogeneity of degree one implies that subjective time delay is measured by a power scale and its discount function (...) becomes a power-exponential type, whereas homogeneity of degree two implies that subjective time delay is measured by a log scale and its discount function becomes a hyperbolic type. Second, a method is shown for constructing a model that can reflect subadditive and superadditive discounting. A non-commutative and non-associative concatenation operation is provided to generate a time string consisting of subdivided durations that incorporates the effect of repeated delay with a subdivided duration. The discounting model is yielded by substituting these strings in an exponential model equipped with a generalized time scale, and the determination of subadditivity or superadditivity depends on whether the discount function value of a product by the non-commutative and non-associative operation is, respectively, smaller or greater than that of a product by an operation of the usual extensive structure. (shrink)

地方自治体もまた一つの“政府”である。市民による自治体と国家は対等である。自治体改革やシビル・ミニマムの理論を創造し、戦後の政治と社会を変革した一政治学者の思想と行動の全貌。新たな都市政策や憲法理論に よって来たるべき市民政府を提唱し、偏狭なナショナリズムを超える未来への道筋を示す。.

The role of the business leader is key to develop the culture of an enterprise. To exemplify its importance in the national and globalcontext, the Muslim author from Indonesia points with admiration to Konosuke Matsushita, founder of Matsushita Electric Corporation, who already in the 1930s set up the seven ethical principles for healthy business growth, which also are commended by the Islamic imperative. Due to the current dynamic business environment, Muslims find themselves confronted with serious dilemmas and need (...) guidance from a clearly developed Islamic business ethics. For this purpose the author offers, first, the essentials of such an ethics: the utmost importance of all sort of productive work and the distribution of wealth in society; the vocation of trade; the fundamental principles of freedom and justice for business conduct; the prescription of certain manners such as leniency, service-motive, and consciousness of Allah; and mutual consultation. He, then, presents his personal view on leadership in business. It involves three basic ingredients: an inspiring vision of high and achievable standards; a value system based on the principles of freedom and justice and promoting fairness, business integrity, and efficiency; and courage to face tough decisions while putting one’s complete trust in Allah. (shrink)

The role of the business leader is key to develop the culture of an enterprise. To exemplify its importance in the national and globalcontext, the Muslim author from Indonesia points with admiration to Konosuke Matsushita, founder of Matsushita Electric Corporation, who already in the 1930s set up the seven ethical principles for healthy business growth, which also are commended by the Islamic imperative. Due to the current dynamic business environment, Muslims find themselves confronted with serious dilemmas and need (...) guidance from a clearly developed Islamic business ethics. For this purpose the author offers, first, the essentials of such an ethics: the utmost importance of all sort of productive work and the distribution of wealth in society; the vocation of trade; the fundamental principles of freedom and justice for business conduct; the prescription of certain manners such as leniency, service-motive, and consciousness of Allah; and mutual consultation. He, then, presents his personal view on leadership in business. It involves three basic ingredients: an inspiring vision of high and achievable standards; a value system based on the principles of freedom and justice and promoting fairness, business integrity, and efficiency; and courage to face tough decisions while putting one’s complete trust in Allah. (shrink)

A finales de la década de los ‘80, Matsushita Electric Industrial Co. Ltd. largó a la venta la primera máquina panificadora de uso doméstico. Su lanzamiento gozó de tal éxito, que sociólogos del conocimiento se abocaron a analizar el conocimiento involucrado en su diseño y producción. Para ello, Takeuchi y Nonaka (1995) analizaron detalladamente la noción de conocimiento tácito (POLANYI, 1966/2009). Defendieron que los ingenieros y desarrolladores lograron explicitar y traducir el conocimiento tácito presente en el ejercicio habilidoso del (...) maestro panadero al diseño de la máquina de hacer pan, reproduciendo el mismo resultado práctico. En el presente trabajo, discutiré su interpretación de la noción de conocimiento tácito y defenderé que el conocimiento tácito involucrado en el ejercicio de habilidades prácticas no puede explicitarse y traducirse en el diseño de la máquina de hacer pan sin perder, al menos, una parte sustancial de dichas habilidades. Para ello, me valdré de aportes de la sociología de la ciencia y de la fenomenología para argumentar que el conocimiento tácito involucrado en el ejercicio habilidoso de nuestro maestro panadero depende de una relación de familiaridad con el entorno. Dicha relación es epistémicamente relevante en la medida en que involucra representaciones aspectuales de nuestro entorno, las cuales permiten guiar la acción de nuestro maestro panadero. A diferencia, la máquina de hacer pan no posee tales representaciones y, en consecuencia, no puede implicar, al menos, el mismo tipo de conocimiento tácito como guía de su comportamiento. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Keigo in Modern Japan: Polite Language from Meiji to the PresentAnn WehmeyerKeigo in Modern Japan: Polite Language from Meiji to the Present. By Patricia J. Wetzel. Honolulu: University of Hawai'i Press, 2004. Pp. 206.In Keigo in Modern Japan: Polite Language from Meiji to the Present, Patricia Wetzel delves deeply into social and analytical aspects of honorific and polite language from historical and contemporary perspectives. It is a work (...) unlike any other, with a rigorous analysis of "language intervention," the attempt to standardize keigo usage, over the last one hundred years. Wetzel envisions the audience for this book as the student of Japan in a broad sense, and there is much in this work to compel the attention of those in history, sociology, and anthropology, in addition to linguistics. Wetzel characterizes her work as a "search for vocabulary," a vocabulary that can account for keigo as a complex, commonsense system that native speakers feel less than secure in their use thereof.The first chapter, "Keigo in Linguistics," surveys analytic frameworks concerning the structure and syntax of honorifics within Western linguistics. Wetzel also proposes [End Page 191] one modification to theory, in arguing that it is the subject that should be regarded as the trigger for honorification in all instances, doing away with the notion of "object honorification." There is also discussion of issues that have been targeted in research on pragmatics and in research from sociolinguistic perspectives.In the second chapter, "Keigo in Kokugogaku," Wetzel locates the inception of Japanese-language studies of keigo in the Meiji period, under the influence of Latin-based Western methodologies, and the move toward universal education. Following Tsujimura's (1992) lead, she identifies three basic frameworks in the early history of the analysis of keigo, namely through "person," "meaning," and "target." Under person-oriented analyses, Wetzel discusses the work of Mitsuhashi, Tokieda, and Tsujimura; under meaning-oriented frameworks, the work of Yoshioka, Hashimoto, and Uchiyama; and under target-oriented approaches the work of Mitsuya and Matsushita. More recently, theoretical discussions have focused on just what is to be included in the analysis of keigo, and have reincorporated the concept of taigū "consideration," first introduced by Okada in 1900. The latter half of the chapter focuses on the recent work of Ō ishi, Minami, and Kikuchi and their debates on whether to incorporate socially meaningful aspects of deportment into the paradigm as well as the vulgar, demeaning, and haughty ranges of expressions.With chapter 3, "Inventing Keigo: Standardization," Wetzel turns to the ideological aspects of keigo, in an investigation of the history of language intervention in Japan. The late Meiji period witnessed the drive to unify the spoken and written idioms in the genbun-itchi movement. Keigo, like other aspects of spoken language, was part of what needed to be pinned down under the process of codifying a standard language for the nation. Wetzel chronicles the succession of official bodies created to address, first of all, standardization of language and, later, a variety of issues including orthographic reforms and keigo use. Among these official bodies are the Kokugo Chō sakai in 1899, Kokugo Chō sa Iinkai in 1902, Rinji Kokugo Chō sakai in 1921, Kokugo Shingikai in 1950, and Bunka Shingikai in 2001. Wetzel argues that keigo acquired "real salience" and "came of age" only in the postwar period. The Kokugo Shingikai issued two policy statements outlining an optimal system of keigo use: Kore kara no keigo (Keigo from now on) (1952) and Gendai ni okeru keii-hyōgen no arikata (Guidelines for respect expressions in the modern age) (1998), both of which Wetzel translates in their entirety and includes in the book's appendixes, along with the original Japanese.In chapter 4, "The Modernization of Keigo," Wetzel studies the social phenomenon of keigo anxiety, as reflected in the plethora of popular how-to manuals on keigo usage, and the occasional "manner poster" displayed in public venues. She applies Giddens' notion of "disembedding," Faircloth's notion of "technologization of discourse," and Bourdieu's concept of "linguistic capital" to help understand why it is that people feel the need to be instructed on the proper use of keigo. Wetzel herself attended several... (shrink)