The aim of this article is to question the nature of the socio-anthropological approach in Lefort’s thought. The author explores the complex relationship between Lefort and the Durkheimian French school of sociology in four stages: in the first, he shows Lefort as a sociologist ‘worthy of its name’ or, in other words, a sociologist interested in questioning the ‘institution of the social’. In the second, he focuses on the disturbing elements that Lefort introduces: the political and the division into the (...) French sociological approach. In the third stage, he focuses his attention on the sociological approach in Lefort’s way of thinking about democratic society. Finally, he concludes by referring to Lefort’s apparent opposition between philosophy and social sciences – and the errors that this may have engendered – in order to demonstrate the continuity of Lefort’s sociological approach. (shrink)

Introduction: Motor evoked potentials (MEPs) to transcranial magnetic stimulation are known to be susceptible to several sources of variability. However, conflicting evidences on individual characteristics in relatively small sample sizes have been reported. We investigated the effect of age, height, and sex on MEPs of the motor cortex and spinal roots in a large cohort. Methods: A total of 587 subjects clinically and neuroradiologically intact were included. MEPs were recorded during mild tonic contraction through a circular coil applied over the (...) “hot spot” of the first dorsal interosseous and tibialis anterior muscles, bilaterally. Central motor conduction time (CMCT) was estimated as the difference between MEP cortical latency and the peripheral motor conduction time by cervical or lumbar magnetic stimulation. Peak-to-peak MEP amplitude to cortical stimulation and right-to-left difference of each parameter were also measured. Results: After Bonferroni correction, general linear (multiple) regression analysis showed that both MEP cortical latency and peripheral motor conduction time at four limbs positively correlated with age and height. At lower limbs, an independent effect of sex on the same measures was also observed (with females showing smaller values than males). CMCT correlated with both age (negatively) and height (positively) when analyzed by a single regression; however, with a multiple regression analysis this significance disappeared, due to the correction for the multicollinearity within the dataset. Conclusions: Physical individual features need to be considered for a more accurate and meaningful MEPs interpretation. Both in clinical practice and in research setting, patients and controls should be matched for age, height, and sex. (shrink)

The article focuses on the social-lexical history of the terms fraternité and solidarité in France during the first half of the 19th century. In particular, the author highlights how, in 1848, fratenité is both used in the motto of the Republic and associated with the defeated socialist republicanism. Then, the author focuses on its synonymous, solidarité, and he reconstructs the different contexts of use of this term , in order to show that its use in the social context accompanies the (...) formation of the first sociological approach with a republican-saint-simonian matrix. (shrink)

The gene regulation function (GRF) provides an operational description of a promoter behavior as a function of the concentration of one of its transcriptional regulators. Behind this apparently trivial definition lies a central concept in biological control: the GRF provides the input/output relationship of each edge in a transcriptional network, independently from the molecular interactions involved. Here we discuss how existing methods allow direct measurement of the GRF, and how several trade‐offs between scalability and accuracy have hindered its application to (...) relatively large networks. We discuss the theoretical and technical requirements for obtaining the GRF. Based on these requirements, we introduce a simplified and easily scalable method that is able to capture the significant parameters of the GRF. The GRF is able to predict the behavior of a simple genetic circuit, illustrating how addressing the quantitative nature of gene regulation substantially increases our comprehension on the mechanisms of gene control. (shrink)

BackgroundSonographic mesenteric pattern in celiac disease (CD) suggests a hyperdynamic circulation. Despite the well-known CD-related neurological involvement, no study has systematically explored the cerebral hemodynamics to transcranial Doppler sonography.Materials and methodsMontreal Cognitive Assessment (MoCA) and 17-item Hamilton Depression Rating Scale (HDRS) were assessed in 15 newly diagnosed subjects with CD and 15 age-, sex-, and education-matched healthy controls. Cerebral blood flow (CBF) velocities and indices of resistivity (RI) and pulsatility (PI) from the middle cerebral artery (MCA), bilaterally, and the basilar (...) artery (BA) were recorded. We also assessed cerebral vasomotor reactivity (CVR) through the breath-holding test (BHT).ResultsWorse scores of MoCA and HDRS were found in patients compared to controls. Although patients showed higher values of CBF velocity from MCA bilaterally compared to controls, both at rest and after BHT, no comparison reached a statistical significance, whereas after BHT both RI and PI from BA were significantly higher in patients. A significant negative correlation between both indices from BA and MoCA score were also noted.ConclusionThese treatment-naïve CD patients may show some subtle CVR changes in posterior circulation, thus possibly expanding the spectrum of pathomechanisms underlying neuroceliac disease and in particular gluten ataxia. Subclinical identification of cerebrovascular pathology in CD may help adequate prevention and early management of neurological involvement. (shrink)

Censure and exclusion of The Republic are characteristics of many utopias, which become dystopias precisely because of turning to them. Plato´s reasons to censure certain types of poetry are ethical and political ones, although his arguments are epistemological . This paper proposes reading these two aspects of the platonic proposal in the light of three specific points of the Timaeus: 1) the theory of discourse about the concept of verisimilar , 2) its relation to the question of whether we can (...) represent objects we do not know, and 3) the demiurge model proposed by Plato in this dialogue. The aim is to show that two of the most problematic aspects of The Republic, are dissolved today in the Timaeus. (shrink)

Antes incluso de que la España de 1992 celebrara e l V centenario del descubrimiento de América, Ferlosio publi có en la prensa varios textos críticos sobre la con q uista que luego fueron reuni dos en Esas Yndias equivocadas y malditas. Comentarios a la historia. Part iend o de aquí, p lante o la s pregunta s de qué es la historia y cómo debería escribirse y ensayo una r esp uesta de sde la crítica de la violencia de (...) Benjamin y la identificación que hace Ferlosio de Historia, Dios, dominación y s entido, fundamento de l a m ora l expiatoria y el principio de intercambio de bienes por valores. D esarrollar é la tesis, compartida por Ferlosio, Dussel y Lomax, de que 1492 fue el año eje entre la Reconquista de la península ibérica y la conquista de América, r etrocederé a la fusión de Cristianismo e Imperio Romano en Nicea, presentare la caracterización hecha por Ferlo sio de la guerra escatológica, cuyo garante es Dios, y rastrear é los antecedentes estoic os d el sentido. Finalizaré con Dussel para m o stra r cómo el discurso histórico puede ser c rític o (Benjamin), transitiv o ( Ferlosio ) y congénito con su objeto ( Timeo ), se lib e re de la lógica del Sentido (Ferlosio) y n o tenga que taparse los ojos ante lo que dice ( Anne Carson ). (shrink)

L'articolo ricostruisce le riflessioni sulla crisi dell'educazione avanzate dal filosofo politico Marcel Gauchet. All'interno di una piů generale analisi delle trasformazioni della societÀ democratica e dell'approfondirsi del processo d'individualizzazione, viene posta all'attenzione la diffusa incapacitÀ di prendere in considerazione la formazione sociale dell'individuo. Solo a partire da tale constatazione č possibile comprendere le mutazioni storiche delle condizioni sociali in cui si educano i bambini. Il saggio si concentra inoltre su alcuni punti specifici dell'analisi della crisi dell'educazione.

Summary Within Husserl’s theory of perception, the role attributed to kinesthetic sensations determines a phase of the perceptive constitution that marks the boundary between pure receptivity and a first form of self-determination of consciousness. Kinesthetic experiences are, in fact, characterized not just as acts that are performed but rather that can be performed, albeit according to predetermined paths. This primitive form of ‘instinctive’ spontaneity of the Ego (linked to primal impulses) as realization of pre-established potentialities, characterizes what Husserl defines the (...) ‘ idiopsychic’ dimension of consciousness (Husserl, 1952, p. 135). However, although this level of consciousness unity presupposes a spontaneous activity, it can be investigated according to the ‘causal’ laws of motivation. The phenomenon of motivation was notoriously introduced by Husserl in §56 of Ideen II, as a specific law of spiritual life. However, there are two possible forms of motivation, one in which the Ego is actively involved, and a second one, called “associative motivation.” The latter basically indicates the passive tendency of creating associations between unities of the immanent sphere. In other terms, Husserl acknowledges the existence of “motivated relations” within the immanent sphere of mental acts which do not necessarily call for an active participation of the Ego. In this sense, the relation between motivating factors and motivated elements could be considered a kind of conditioning of the form “because-therefore,” in which the two elements arrange themselves in a succession of experiences. This work aims to show that this very kind of association is the same that pre-determines the unfolding possibility of kinesthetic chains. (shrink)

In the Summa theologiae, Aquinas distinguishes between an extrinsic and an intrinsic beatitude, the first being caused by God and the latter by human acts. The sixteenth-century Salamanca commentators on the Summa concentrate their interpretative efforts on the intrinsic beatitude, assigning to the human acts an indispensable role in order to reach beatitude. Their main concern is to refute the Lutheran conception of man’s passive role in his own justification.

Resumen La censura y la exclusión de la República son características de muchas utopías, las cuales se convierten en distopías precisamente por recurrir a ellas. Las razones de Platón para censurar determinados tipos de poesía son de índole ético-política, si bien sus argumentos son de carácter epistemológico (los poetas representan mal, sus mitos son falsos). Este trabajo propone leer estos dos aspectos de la propuesta platónica a la luz de tres puntos específicos del Timeo: 1) la teoría del discurso en (...) torno al concepto de "verosímil" (eikós) 2) su relación con la pregunta sobre si podemos representar objetos que no conocemos y 3) el modelo de demiurgo propuesto por Platón en dicho diálogo. El objetivo es mostrar que dos de los aspectos más problemáticos de ayer, la República, se disuelven hoy en el Timeo.Censure and exclusion of The Republic are characteristics of many utopias, which become dystopias precisely because of turning to them. Plato's reasons to censure certain types of poetry are ethical and political ones, although his arguments are epistemological (the poets represent in a wrong way, their myths are false). This paper proposes reading these two aspects of the platonic proposal in the light of three specific points of the Timaeus: 1) the theory of discourse about the concept of verisimilar (eikos), 2) its relation to the question of whether we can represent objects we do not know, and 3) the demiurge model proposed by Plato in this dialogue. The aim is to show that two of the most problematic aspects of The Republic, are dissolved today in the Timaeus. (shrink)

La question 104 de la II a II ae n’est qu’une de celles de la Summa theologiae où Thomas d’Aquin réfléchit sur l’obéissance, en théorisant sa nécessité à tous les niveaux de la réalité et en établissant sa portée et ses limites. Lorsque la réflexion de Thomas est appliquée à un contexte doctrinal et historique différent à divers égards, cette réflexion ouvre à l’inclusion d’éléments nouveaux, déclenchant ainsi une nouvelle discussion sur les relations complexes entre les autorités à obéir et (...) le sujet qui obéit, en les considérant dans leurs multiples aspects problématiques. C’est ce qu’on peut constater dans les commentaires de la Summa theologiae de Francisco de Vitoria, Luis de Molina et Pedro Luis. La nécessité d’éprouver ou d’adapter la théorie thomasienne de l’obéissance à une réalité qui doit faire face, avant tout, au protestantisme, conduit ces auteurs à focaliser leur attention sur des cas où le sujet qui doit obéir se trouve dans des situations d’impasse. La résolution des cas d’impasse les plus difficiles – par exemple le doute impliquant l’ordre du prélat – passe également par la récupération d’un élément clé de la réflexion proposée par Thomas dans la q. 104 : la caractérisation de l’obéissance comme vertu spécifique. (shrink)

Qu’est-ce que le travail? La question posée par le titre de ce recueil offre un tremplin pour des réponses multiples et nuancées, fruits de recherches sur un large spectre temporel et spatial. Les articles qui le composent répondent à cette question en interrogeant la façon dont le genre définit notre compréhension du travail. Se trouvent donc placés au premier plan les problèmes relatifs à l’égalité, le rôle du marché versus l’espace privé, la question des capacités de production comparée a...

In the second half of the sixteenth century, many universities influenced by Salamanca adopted the Summa theologiae as the textbook for teaching scholastic theology. At the same time, the universities decided that some minor chairs should teach one of the Sentences commentaries written by one of the following authors: Duns Scotus, Durand of Saint-Pourçain, or Gabriel Biel. As a result, some commentaries on these commentaries started to appear. This is most notably the case when it comes to the University of (...) Coimbra, where Aquinas’s Summa became the textbook only very late and where the chairs of Scotus, Durand and Biel were instituted in the second half of the century. This article provides a list of questions making up thirteen commentaries produced in Coimbra, where, unlike what happened in Salamanca, the professors belonged to different religious orders. It also presents the list of questions of one commentary connected with a Franciscan convent. Some reflections on the need to study late-scholastic manuscripts as well as on the structure of these commentaries are also offered. (shrink)

A new installment in the series that blew readers' minds with Biocentrism and Beyond Biocentrism, The Grand Biocentric Design offers an even deeper dive in to the nature of reality and our universe based on the latest groundbreaking research.

The aim of this work is to analyze some aspects that can have an influence on our evaluation of conditional statements. The final purpose is to provide a methodological frame of evaluation of this kind of statements without taking into account the truth values of antecedent and consequent as Formal Logic has been usually assumed.

This paper addresses the existence of Hopf bifurcations in a directed acyclic network of neurons, each of them being modeled by a Hindmarsh–Rose neuronal model. The bifurcation parameter is the small parameter corresponding to the ratio of time scales between the fast and the slow dynamics. We first prove that, under certain hypotheses, the single uncoupled neuron can undergo a Hopf bifurcation. Hopf bifurcation occurrences in a directed acyclic network of HR neurons are then discussed. Numerical simulations are carried out (...) to observe these bifurcations and to illustrate the theoretical results. (shrink)

En unos tiempos donde se cuestiona la utilidad de la Lógica dentro de los planes de estudio de Filosofía, llega, como maná caído del cielo, esta pequeña guía sobre argumentación y retórica de José Miguel Sagüillo. Pocas veces se han expresado tantos conceptos lógicos con tal claridad en un espacio tan breve. Sin duda, el libro constituye una herramienta pedagógicamente impecable para profesores y alumnos de Lógica, Retórica o Teoría de la Argumentación y una fuente de información imprescindible para el (...) ciudadano de a pie que tenga cierta querencia por el buen razonar y trate de evitar sucumbir a las sutiles garras de la manipulación retórica. Además, este pequeño tratado deja sin excusas a los que pretenden denigrar a la Lógica calificándola de incomprensible para los que son más diestros en las letras que en las ciencias o desconectada del campo de la Filosofía. (shrink)