The debate between Classicism and Connectionism can be properly characterized as a debate concerning the appropriate levels of analysis for psychological theorizing. Classicists maintain that the level of analysis defined by the Classical architecture is the level of analysis at which psychological theorizing should reside. This level is called the symbolic level. On the other hand, Connectionists claim that the proper level of analysis for cognitive modeling is at the subsymbolic level which is considered a level lower than the symbolic (...) level. This thesis argues that both Classicism and Connectionism characterized in the above way are single-level approaches. It is argued in this thesis that Classicism is wrong in denying the cognitive relevancy of the lower-level theorizing; and some forms of Connectionism should be rejected because they underestimate the theoretical significance of the higher-level modeling. ;The concept of level is widely employed by philosophers and cognitive scientists, but has not received sufficient analysis. This thesis offers a general theory of levels, and evaluates Classicism and Connectionism on the basis of this general theory of levels. Basically this thesis argues that a cognitive system should be regarded as a system organized into a hierarchy of levels of organization. Different levels of organization may demand different levels of analysis. This thesis argues that each level of analysis enjoys a degree of autonomy, i.e., it is not totally reducible to the lower-level analysis. The traditional dichotomy of the cognitive and the implementational levels is too simplistic and overlooks the complexity of a cognitive system. Not all levels of organization of a system are cognitively relevant. But much empirical evidence has shown that many levels of organization are either strongly relevant or at least weakly relevant to cognitive modeling. It would be theoretically more plausible and fruitful to adopt a multi-level approach which takes many levels of analysis seriously in cognitive modeling. A very general picture of a multi-level approach to the mind is depicted in this thesis. (shrink)

Both Carnap and Quine made significant contributions to the philosophy of mathematics despite their diversedviews. Carnap endorsed the dichotomy between analytic and synthetic knowledge and classified certainmathematical questions as internal questions appealing to logic and convention. On the contrary, Quine wasopposed to the analytic-synthetic distinction and promoted a holistic view of scientific inquiry. The purpose of thispaper is to argue that in light of the recent advancement of experimental mathematics such as Monte Carlosimulations, limiting mathematical inquiry to the domain of (...) logic is unjustified. Robustness studies implemented inMonte Carlo Studies demonstrate that mathematics is on par with other experimental-based sciences. (shrink)

Lateral temporal measures of the auditory evoked potential including the T-complex, as well as an earlier negative peak index maturation of auditory/speech processing. Previous studies have shown that these measures distinguish neural processing in children with typical language development from those with disorders and monolingual from bilingual children. In this study, bilingual children with Turkish as L1 and German as L2 were compared with monolingual German-speaking children with developmental language disorder and monolingual German-speaking children with TD in order to disentangle (...) effects of limited language input vs. reduced perceptual abilities in the processing of speech and non-speech stimuli. Sensory processing reflected by the T-complex was compared in response to a German vowel and a sine-wave tone in the three groups of children, ages 5 through 6 years. Stimuli were presented while children watched a muted video. Auditory evoked potentials were time-locked to the vowels and tones. AEPs to the frequent stimuli within an oddball paradigm were analyzed at the left and right temporal electrode sites.The results revealed language status, stimulus, and language test measures all influenced the T-complex amplitudes. Particularly, the peak amplitude of Ta was modulated by language status and stimulus type. Bilingual children had significantly more negative Ta responses than the monolingual children with TD for both vowels and tones while DLD children differed from TD children only for the vowel stimulus. The amplitude of the T-complex was overall more negative at the left than at the right site. The Na peak latency was longer for the bilingual group than that observed for the two monolingual groups. The Tb latency was shorter for DLD and bilingual groups than that for TD children in the vowel condition, but no such latency difference between DLD and bilingual children was found. We suggest that the attenuated T-complex for bilingual children indicates continued plasticity of the auditory cortex to allow for learning of novel, second-language speech sounds. (shrink)

Ṣadr al-Dīn Shīrāzī, Muḥammad ibn Ibrāhīm, -1641--Criticism and interpretation. ; Islamic philosophy.

Many studies have observed modulation of the amplitude of the neural index mismatch negativity (MMN) related to which member of a phoneme contrast [phoneme A, phoneme B] serves as the frequent (standard) and which serves as the infrequent (deviant) stimulus (i.e., AAAB vs. BBBA) in an oddball paradigm. Explanations for this amplitude modulation range from acoustic to linguistic factors. We tested whether exchanging the role of the mid vowel /ε/ vs. high vowel /ɪ/ of English modulated MMN amplitude and whether (...) the pattern of modulation was compatible with an underspecification account, in which the underspecified height values are [−high] and [−low]. MMN was larger for /ε/ as the deviant, but only when compared across conditions to itself as the standard. For the within-condition comparison, MMN was larger to /ɪ/ deviant minus /ε/ standard than to the reverse. A condition order effect was also observed. MMN amplitude was smaller to the deviant stimulus if it had previously served as the standard. In addition, the amplitudes of late discriminative negativity (LDN) showed similar asymmetry. LDN was larger for deviant /ε/ than deviant /ɪ/ when compared to themselves as the standard. These findings were compatible with an underspecification account, but also with other accounts, such as the Natural Referent Vowel model and a prototype model; we also suggest that non-linguistic factors need to be carefully considered as additional sources of speech processing asymmetries. (shrink)

Wir leben in einer Welt, in der die verschiedenen Kulturen und Religionen zunehmend eine gemeinsame Antwort auf die ethischen Fragen unseres Zusammenlebens finden müssen. Dieser Band leistet deshalb zweierlei: Einerseits informiert er über die übergreifenden ethischen Traditionen und Paradigmen in den Kulturregionen und in den größeren und kleineren Religionsgemeinschaften dieser Welt. Andererseits versucht er, die Grundlagen bereitzustellen, die eine völkerübergreifende Verständigung über die Grundfragen der Moral ermöglichen können. Wer über den Tellerrand eines ausschließlich im Westen entwickelten Diskurses hinausblicken und den (...) interkulturellen Dialog fruchtbar führen will, findet mit diesem Band das unentbehrliche Hilfsmittel. (shrink)

​Vielleicht nie zuvor war Toleranz so wichtig wie in der heutigen Welt, in der Menschen verschiedenster Kulturregionen und Religionsgemeinschaften zusammenkommen. Der Toleranzbegriff wird nach wie vor fast ausschließlich aus der Perspektive der europäisch-westlichen Traditionen dargestellt. Mit dem vorliegenden Band wird zum ersten Mal versucht, umfassend in die Weltgeschichte der Toleranz einzuführen. Über 30 Autoren aus verschiedenen Fachgebieten und Nationen haben ihre Forschungen zu Methoden und Themen der Toleranzfrage zusammengetragen. So ist sowohl ein einführendes und weitere Forschungen anregendes Kompendium als auch (...) ein Lehrbuch für Studierende der Sozial- und Kulturwissenschaften, der Philosophie, Theologie, Rechts- sowie Religionswissenschaft entstanden. (shrink)

Cyclin-dependent kinase 5 has been implicated in Alzheimer's disease pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5, led to increased levels of BACE1 mRNA and protein in vitro and in vivo. A p25/cdk5 responsive region containing multiple sites for signal transducer and activator of transcription was identified in the BACE1 promoter. STAT3 interacts with the BACE1 promoter, and p25-overexpressing mice had elevated levels of pSTAT3 and BACE1, whereas cdk5-deficient mice had reduced levels. Furthermore, mice with a (...) targeted mutation in the STAT3 cdk5 responsive site had lower levels of BACE1. Increased BACE levels in p25 overexpressing mice correlated with enhanced amyloidogenic processing that could be reversed by a cdk5 inhibitor. These data demonstrate a pathway by which p25/cdk5 increases the amyloidogenic processing of APP through STAT3-mediated transcriptional control of BACE1 that could have implications for AD pathogenesis. (shrink)

Purpose: to characterize ethics course content, structure, resources, pedagogic methods, and opinions among academic administrators and course directors at U.S. medical schools. Method: An online questionnaire addressed to academic deans and ethics course directors identified by medical school websites was emailed to 157 Association of American Medical Colleges member medical schools in two successive waves in early 2022. Descriptive statistics were utilized to summarize responses. Results: Representatives from 61 (39%) schools responded. Thirty-two (52%) respondents were course directors; 26 (43%) were (...) deans of academic affairs, medical education, or curriculum; and 3 with other roles also completed the survey (5%). All 61 schools reported some form of formal ethics education during the first year of medical school, with most (n = 54, 89%) reporting a formal mandatory introductory course during preclinical education. Schools primarily utilized lecture and small-group teaching methods. Knowledge-based examinations, attendance, and participation were most commonly used for assessment. A large majority regarded ethics as equally or more important than other foundational courses, but fewer (n = 37, 60%) provided faculty training for teaching ethics. Conclusions: Despite a response rate of 39 percent, the authors conclude that medical schools include ethics in their curricula in small-group and lecture formats with heterogeneity regarding content taught. Preclinical curricular redesigns must innovate and implement best practices for ensuring sound delivery of ethics content in future curricula. Additional large-scale research is necessary to determine said best practices. (shrink)

Ibn al-Fārid, Muqadimāt fī al-taṣawwuf.--2. Abū al-ʻAlāʼ al-Maʻarrī fī Luzūmiyyātih.--3. Muqaddimat Ibn Khaldūn.--4. al-Ghazālī. 2 v.--5. Ibn Ṭufayl.--6. Ibn Rushd. 2 v.--7. Ikhwān al-Safāʼ--8. al-Kindī.--9. al-Farābī. 2 v.--10. Ibn Sīnā. 2 v.

Prospective memory is the ability to perform a planned action at a future time, while carrying on with other unrelated tasks. Implementation Intentions is a promising metacognitive strategy for improving PM in older adults, though its generalization and longer-term effects are not well-understood. We examined the effects of II on PM in 48 community-dwelling older adults and 59 young adults. Participants were randomly allocated to a conventional instruction or II group and administered a laboratory-based PM task in the first session. (...) In the second session, participants returned to complete a similar but new laboratory-based PM task and an ecological PM task without prompts to use a strategy. We found strong age effects on PM performance whereby older adults performed worse than young adults across all PM tasks. While the overall facilitation effect of II was not statistically significant, there was a trend that this strategy facilitated PM performance on the laboratory-based PM task in the first session for older adults with a medium sized effect. The generalization and longer-term effect of II were not significant for either the similar laboratory-based or the ecological PM task. These results suggest that a single-session II intervention may not be sufficient to elicit transfer to other similar new PM tasks in healthy populations. (shrink)

Prospective memory is the ability to perform a planned action at an intended future time. This study examined the neural correlates of PM using functional near-infrared spectroscopy. This study employed a within-participants design. A laboratory PM task was adapted for use with fNIRS to investigate regions of interest and levels of brain activation during task performance in 32 participants. Participants first completed a working memory task followed by a WM plus PM task while neural activity was measured using fNIRS. Behavioral (...) results revealed an interference effect for reaction time on the WM task, whereby participants were significantly slower to respond in the WM plus PM task compared to the WM task. Ongoing task accuracies did not differ between the two conditions. fNIRS results revealed a higher level of neural activity in the fronto-polar prefrontal cortex and dorsolateral prefrontal cortex in the WM plus PM task compared to the WM Condition. These findings highlight that fNIRS is a suitable tool for studying and understanding the neural basis of PM. (shrink)