In this review, we discuss a novel on‐site remodeling function that is mediated by the H2A‐ubiquitin binding protein ZRF1. ZRF1 facilitates the remodeling of multiprotein complexes at chromatin and lies at the heart of signaling processes that occur at DNA damage sites and during transcriptional activation. In nucleotide excision repair ZRF1 remodels E3 ubiquitin ligase complexes at the damage site. During embryonic stem cell differentiation, it contributes to retinoic acid‐mediated gene activation by altering the subunit composition of the Mediator complex. (...) We postulate that ZRF1 operates in conjunction with cellular remodeling machines and suggest that on‐site remodeling might be a hallmark of many chromatin‐associated signaling pathways. We discuss yet unexplored functions of ZRF1‐mediated remodeling in replication and double strand break repair. In conclusion, we postulate that on‐site remodeling of multiprotein complexes is essential for the timing of chromatin signaling processes. (shrink)

“Mother dear, I simply cannot weave my cloth; I'm overpowered by desire for a slender young man—and it's Aphrodite's fault.”“The Greeks required a woman to devote herself to the sedentary tranquillity of woolwork.”Sappho, Xenophon: these two juxtaposed texts, chosen for their dissonant tones, well introduce the Greek representation of weaving as a privileged metaphoric terrain defining the presence and the essence of an imaginary feminine, often expressed in antithetical terms, as a polarized place, with an ever precarious equilibrium. As discourse, (...) weaving is no longer a naturalistic depiction of an edifying occupation of the gynaeceum, an answer to the day-to-day realty of household tasks. As a literary object or ritualized activity, the loom appears as a “gendered” space, a place symbolic of feminine activity. (shrink)

Les objets publiés ici (2 outils, 6 armes et 1 vase), entrés au Musée Bénaki, proviennent de différentes collections privées sans que le lieu de trouvaille soit connu. Les deux outils nos 1-2, les 3 poignards nos 3, 4, 6 et le fer de lance n° 8, sont de types connue, datant de différentes périodes de l'Âge du Bronze. L'épée n° 5 appartient à un type intermédiaire entre les groupes Β et G et a dû être fabriquée en Grèce à (...) l'Helladique Récent II B-III A. Des animaux au galop (un lion et un cerf) ont été gravés à l'époque moderne, à l'imitation d'autres armes mycéniennes, sur la lame du poignard n° 7, qui date du HR III B. Le cratère n° 8, du HR III A 2 1-B, est décoré d'une scène unique, bizarre, avec trois animaux (cervidés ou caprins) ; il est sans doute d'origine chypriote. (shrink)

This paper employs an eclectic mix of paradigms in order to discuss constituting characteristics of young children's learning experiences. Drawing upon a phenomenological perspective it examines learning as a form of ‘Being’ and as the result of learners’ engagement with the world in their own, unique, intentional manners. The learners’ intentions towards their world are expressed in everyday activity and participation. A social constructivist perspective is thus employed to present learning as situated in meaningful socio‐cultural contexts of the everyday, lived (...) world and as a form of participation in those settings. These characteristics of learning are brought together into a holistic, synthesised model, a Gestalt of learning. The proposed synthesis has relevance for and is applicable to educational contexts as a means of making sense of children's learning experiences and of promoting and facilitating them. (shrink)

This paper employs an eclectic mix of paradigms in order to discuss constituting characteristics of young children's learning experiences. Drawing upon a phenomenological perspective it examines learning as a form of 'Being' and as the result of learners' engagement with the world in their own, unique, intentional manners. The learners' intentions towards their world are expressed in everyday activity and participation. A social constructivist perspective is thus employed to present learning as situated in meaningful socio-cultural contexts of the everyday, lived (...) world and as a form of participation in those settings. These characteristics of learning are brought together into a holistic, synthesised model, a Gestalt of learning. The proposed synthesis has relevance for and is applicable to educational contexts as a means of making sense of children's learning experiences and of promoting and facilitating them. (shrink)

L’usage de la forme catalogique et de la généalogie inscrit les auteurs dans une filiation intellectuelle. Partant de cette hypothèse, l’article réexamine la question de l’influence homérique sur l’œuvre d’Hérodote face à l’influence hésiodique sur la naissance de l’historio­graphie. L’objectif est de montrer que la manipulation de la forme catalogique est un critère d’innovation autant de l’école homérique face à l’école hésiodique que d’Hérodote face au style historiographique dominant. Les options poétiques « originelles » divergentes semblent ainsi avoir exercé une (...) influence durable sur le processus de la formation des genres en Grèce ancienne. Departing from the hypothesis that the use of catalogues and genealogies assigns authors to an intellectual genealogy, this paper re-examines the Homeric influence on Herodotus compared to the Hesiodic influence on the beginnings of historiography. The use of catalogues can be envisaged as a criterion of innovation, when one compares on this point the Homeric and Hesiodic “schools” as well as Herodotus and contemporary historiographers, and shows the lasting influence of the originally divergent poetic options on the process of the formation of genres in ancient Greece. (shrink)

The paper presents the main preliminary findings of GEITONIA research project (Growing and Enabling of Information Technologies for Online Neighborhoods: Implications and Applications). Focusing on the development of a local social network for neighborhoods of Nea Smyrni community in Attica (Greece), the main results of an exploratory mixed methods research study, are discussed. The local social network is a non-commercial social medium that operates as a mobile application. Residents of the local community will have the opportunity to use the application (...) for a pilot period, create their virtual neighborhoods, interact with other neighbors, and expand local social ties in a continuum of physical and virtual spatialities. Moreover, taking into consideration residents’ perceptions, demands and visions, regarding a local social network for their neighborhoods, the research project aims to enhance the rule that sets the focus on the users, as co-creators and co-producers of communication technologies. (shrink)

This article discusses the relationship between the post-2008 global economic crisis and trauma journalism through a quantitative study of reporters covering austerity’s everyday manifestations and examines the effects on the media professionals involved. The findings indicate that journalists who cover economic crisis-related incidents suffer specific symptoms of trauma. As such, the study re-conceptualizes the economic crisis as primarily affective for media workers, it establishes a direct correlation between the economic crisis and emotional trauma, and provides an insight into the kind (...) of trauma that stems from covering austerity and its impact on society. A regression analysis of symptoms indicates trauma journalism as an emerging field of research into the economic crisis. (shrink)