The U.S. National Institute of Allergies and Infectious Diseases and the National Institute of Mental Health have a new research priority: inclusion of terminally ill persons living with HIV in HIV cure-related research. For example, the Last Gift is a clinical research study at the University of California San Diego for PLWHIV who have a terminal illness, with a prognosis of less than 6 months. As end-of-life HIV cure research is relatively new, the scientific community has a timely opportunity to (...) examine the related ethical challenges. Following an extensive review of the EOL and HIV cure research ethics literature, combined with deliberation from various stakeholders and our experience with the Last Gift study to date, we outline considerations to ensure that such research with terminally ill PLWHIV remains ethical, focusing on five topics: 1) protecting autonomy through informed consent, 2) avoiding exploitation and fostering altruism, 3) maintaining a favorable benefits/risks balance, 4) safeguarding against vulnerability through patient-participant centeredness, and 5) ensuring the acceptance of next-of-kin/loved ones and community stakeholders. EOL HIV cure-related research can be performed ethically and effectively by anticipating key issues that may arise. While not unique to the fields of EOL or HIV cure-related research, the considerations highlighted can help us support a new research approach. We must honor the lives of PLWHIV whose involvement in research can provide the knowledge needed to achieve the dream of making HIV infection curable. (shrink)

There are some texts about moral sentences in the Islamic logical literature especially in the logical books of Ibn Sina that have been interpreted in completely opposite ways. Relying on these texts, some scholars take Ibn Sina to be proposing a non-cognitive theory of ethics and to the contrary some scholars hold that he is a proponent of a sort of moral intuitionism. Reflecting on the alleged textual evidence in Ibn Sina’s books, I propose a middle way in the interpretation (...) that accepts the cognitive status of the moral sentences but at the same time rejects intuitionism. (shrink)

In this paper I will discuss the main approaches of moral epistemology in the major sects of Islamic theology; the Mu’tazilah and Shi‘ite, who formulated rationalistic ethical system between the eighth and tenth centuries, and the Ash‘arites, who developed a voluntaristic system of morality. At first the answer of Mu’tazila and Shi‘ite to the main question of moral epistemology namely the justification of moral beliefs will be discussed and compared with the intuitionism of Western ethics. Secondly the voluntarism of Ash‘arite (...) concerning the moral knowledge will be discussed and rejected. (shrink)

Divine Motivation theory is an ethical theory with a theological foundation, attempting to explain the relation between religion and morality in the context of Christian theology with emphasizing on neo-Aristotelian and motivation-based ethics. This theory that is presented by Linda Zagzebski, provides a new form of virtue ethics that God's motives, especially that of love, are foundations of moral life and these motivational states are considered ontologically and explanatorily the basis for all moral properties and values. This theory uses five (...) steps to advance its destination. In the first step, this theory proves the personhood of God. In the second step, it argues that God has perfect virtues and motives. In the third step, it shows that God's motive in the Creation is motive of love that is the central and fundamental divine motive. In the fourth step, it discusses the doctrine of imitatio Dei and focuses on the problems of this doctrine. In the last step, it attempts to link this doctrine to the doctrine of the incarnation to resolve its problems. (shrink)

نسبی‌انگاری اخلاقی یکی از مکاتب کهن فرااخلاقی است که به وجود ویژگی‌های اخلاقی، و صدق و توجیه احکام اخلاقی می‌پردازد. با این حال، بخشی از بحث‌های مربوط به نسبی‌انگاری متوجّه معناشناسی جملات نسبی است. نظریات نسبی‌انگارانۀ سنّتی زمینه‌گرا هستند، به این معنا که احکام اخلاقی را دارای عنصری می‌دانند که به نحوی ارجاع به گوینده دارد. این دیدگاه نسبی‌انگاری را با چالش‌هایی مواجه می‌کند، از جمله این‌که اختلاف نظر که یکی از اسباب عمدۀ گرایش به نسبی‌انگاری است، به سوء تفاهم (...) فروکاسته می‌شود. برخی نسبی‌انگاران اخیراً تلاش کرده‌اند تا نظریاتی ارائه دهند که با ثابت دانستن محتوای احکام، دچار مشکلات زمینه‌گرایی سنتی نباشد. یکی از این تلاش‌ها، نظریۀ نسبی‌انگاریِ دربارۀ خود (de se relativism) اندی ایگن است. ایگن با ترکیب نظریۀ دیوید لویس درباب محتوای باور، نظریۀ رابرت استالنیکر درباب اظهار، و نظریۀ استعدادی دیوید لویس درباب ارزش، بر آن است که نظریه‌ای نسبی‌انگارانه دربارۀ ارزش ارائه کند که با طبیعی‌انگاری، درونی‌انگاری احکام اخلاقی، و شناختی‌انگاری سازگار باشد، و از اشکالات دیگری که خودِ او بر زمینه‌گرایی وارد می‌کند مبرّا باشد. در این مقاله نظریۀ ایگن بررسی می‌شود و نشان داده می‌شود که نظریۀ او نه‌تنها از اشکالات وارد بر زمینه‌گرایی رها نیست، بلکه به دلیل پذیرش نظریۀ لویس در باب محتوای باور بار بیشتری بر دوش دارد که آن را نسبت به دیگر نظریات نسبی‌انگارانه مرجوح می‌سازد. -/- . (shrink)

This paper is going to re-read Imam Mohammad al-Ghazali’s moral ideas in order to find the responses to the questions of moral psychology. Al-Ghazali, following the Greek and Islamic philosophers, relates each virtue or vice to a particular faculty in man’s soul. Moreover, following the Asharites, he considers the basis of moral good and badness to be religious. Furthermore, having mentioned al-Ghazali and Hume’s opinions as well as their similarities, this writing explains why al-Ghazali’s view on the moral motivation has (...) not encountered Hume’s objections. And finally, it presents the differences between al-Ghazali and the Greek philosophers’ views on virtues and vices as well as evaluates al-Ghazali’s psychological opinions in ethics. (shrink)

The enjoyment and pleasure derived from sad music has sparked fascination among researchers due to its seemingly paradoxical nature in producing positive affect. Research is yet to develop a comprehensive understanding of this “paradox.” Contradictory findings have resulted in a great variability within the literature, meaning results and interpretations can be difficult to derive. Consequently, this review collated the current literature, seeking to utilize the variability in the findings to propose a model of differential sad states, providing a means for (...) past and future findings to be interpreted. The proposed model is based on theoretical understanding, as such it requires full empirical support. Comparisons to alternative models, theoretical, clinical, and cognitive implications, as well as future directions are discussed. (shrink)

Tabatabai’s theory about the meaning of life can be referred to as active objectivism, where a man plays an important role in achieving the meaningful life, rather than merely discovering the divine view about his existence. If the man chooses the divine purpose from a “real life” perspective as his meaning of life, God’s purpose and man’s purpose will converge in order to shape a meaningful life and the ultimate achievement of Pure Life. However, if he chooses the unreal counterpart, (...) he will be trapped in an unreal life which is referred to as the “pseudo-meaningful life.” It is necessary that human beings discover the divine purpose with the help of conceptual intellect, define the essentials of achieving the purpose with his practical intellect and ultimately, choose the essentials with his own free will. To achieving compliance of a man’s purpose with the divine goal requires faith and good deeds. (shrink)

Theories of decision-making and its neural substrates have long assumed the existence of two distinct and competing valuation systems, variously described as goal-directed vs. habitual, or, more recently and based on statistical arguments, as model-free vs. model-based reinforcement-learning. Though both have been shown to control choices, the cognitive abilities associated with these systems are under ongoing investigation. Here we examine the link to cognitive abilities, and find that individual differences in processing speed covary with a shift from model-free to model-based (...) choice control in the presence of above-average working memory function. This suggests shared cognitive and neural processes; provides a bridge between literatures on intelligence and valuation; and may guide the development of process models of different valuation components. Furthermore, it provides a rationale for individual differences in the tendency to deploy valuation systems, which may be important for understanding the manifold neuropsychiatric diseases associated with malfunctions of valuation. (shrink)

Tabatabai’s theory about the meaning of life can be referred to as active objectivism, where a man plays an important role in achieving the meaningful life, rather than merely discovering the divine view about his existence. If the man chooses the divine purpose from a “real life” perspective as his meaning of life, God’s purpose and man’s purpose will converge in order to shape a meaningful life and the ultimate achievement of Pure Life. However, if he chooses the unreal counterpart, (...) he will be trapped in an unreal life which is referred to as the “pseudo-meaningful life.” It is necessary that human beings discover the divine purpose with the help of conceptual intellect, define the essentials of achieving the purpose with his practical intellect and ultimately, choose the essentials with his own free will. To achieving compliance of a man’s purpose with the divine goal requires faith and good deeds. (shrink)

Persian translation by Mohsen Javadi of 'Recent Work on the Meaning of Life' (first published in Ethics 2002).

وارد کردن شانس به حوزۀ اخلاق به این معناست کهعواملی خارج از کنترل شخص‌ در سعادت‌مندی او دخیل‌ و دارای تأثیر‌اند. از آن‌جا که ارسطو نیل به سعادت را به داشتن فضایل و بهره‌مندی از خواسته‌های بیرونی منوط کرده و «خوش‌بخت بودنِ طبیعی انسان‌ها» را نیز مسئله‌ای اخلاقی انگاشته است، به‌ نظر می‌رسد به‌نوعی شانسِ محیطی و نهادینه را به سعادت آدمی راه داده است، اما با این همه، شانس را در ارزیابی مسئولیت و شأن اخلاقی فرد مؤثر ندانسته است. (...) از همین‌رو، جولیا آناس - فیلسوف نوارسطویی معاصر - ارسطو را مرتکب امر متناقض‌نمای «شانس اخلاقیِ محیطی و نهادینه» می‌داند. در این مقاله ضمن بررسی چگونگی ورود شانس به حوزۀ اخلاق از سوی ارسطو، به مرورِ دیدگاه جولیا آناس در این زمینه می‌پردازیم. آناس با گزینش رویکردی متزلزل، در نهایت، به این نتیجه می‌رسد که نمی‌توان به قطعیتی میان آراء رواقیون و ارسطو در باب این موضوع دست یافت. بنابراین، آناس با چشم‌پوشی نکردن از رأی رواقیون مبنی بر این‌که «سعادت‌مندیِ انسان به‌طورکلی مبرّا از شانس است» مسئولیت انسان و شأن اخلاقی او را نادیده نمی‌انگارد و از این رو مرتکب شانس اخلاقی نمی‌شود. | [email protected] ** استاد گروه فلسفه و کلام دانشگاه قم | [email protected]. (shrink)