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  1.  28
    The Ebola Outbreak in Western Africa: Ethical Obligations for Care.Aminu Yakubu, Morenike Oluwatoyin Folayan, Nasir Sani-Gwarzo, Patrick Nguku, Kristin Peterson & Brandon Brown - 2016 - Journal of Medical Ethics 42 (4):209-210.
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  2.  15
    Ethical Considerations for HIV Cure-Related Research at the End of Life.Karine Dubé, Sara Gianella, Susan Concha-Garcia, Susan J. Little, Andy Kaytes, Jeff Taylor, Kushagra Mathur, Sogol Javadi, Anshula Nathan, Hursch Patel, Stuart Luter, Sean Philpott-Jones, Brandon Brown & Davey Smith - 2018 - BMC Medical Ethics 19 (1):83.
    The U.S. National Institute of Allergies and Infectious Diseases and the National Institute of Mental Health have a new research priority: inclusion of terminally ill persons living with HIV in HIV cure-related research. For example, the Last Gift is a clinical research study at the University of California San Diego for PLWHIV who have a terminal illness, with a prognosis of less than 6 months. As end-of-life HIV cure research is relatively new, the scientific community has a timely opportunity to (...)
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  3.  7
    A Call for Radical Transparency Regarding Research Payments.Emily E. Anderson & Brandon Brown - 2021 - American Journal of Bioethics 21 (3):45-47.
    In the target article “Promoting Ethical Payment in Human Infection Challenge Studies,” Fernandez Lynch et al. call for more information sharing about research payment amounts to study parti...
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  4.  5
    Ethics of HIV Cure Research: An Unfinished Agenda. [REVIEW]Jeremy Sugarman, John A. Sauceda, Brandon Brown, Parya Saberi, Mallory O. Johnson, Laney Henley, Samuel Ndukwe, Hursch Patel, Morénike Giwa Onaiwu, Danielle M. Campbell, David Palm, Orbit Clanton, David Kelly, Jan Kosmyna, Michael Louella, Laurie Sylla, Christopher Roebuck, Nora Jones, Lynda Dee, Jeff Taylor, John Kanazawa & Karine Dubé - 2021 - BMC Medical Ethics 22 (1):1-14.
    BackgroundThe pursuit of a cure for HIV is a high priority for researchers, funding agencies, governments and people living with HIV. To date, over 250 biomedical studies worldwide are or have been related to discovering a safe, effective, and scalable HIV cure, most of which are early translational research and experimental medicine. As HIV cure research increases, it is critical to identify and address the ethical challenges posed by this research.MethodsWe conducted a scoping review of the growing HIV cure research (...)
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  5. Ethical and Practical Considerations for HIV Cure-Related Research at the End-of-Life: A Qualitative Interview and Focus Group Study in the United States.Karine Dubé, Davey Smith, Brandon Brown, Susan Little, Steven Hendrickx, Stephen A. Rawlings, Samuel Ndukwe, Hursch Patel, Christopher Christensen, Andy Kaytes, Jeff Taylor, Susanna Concha-Garcia, Sara Gianella & John Kanazawa - 2022 - BMC Medical Ethics 23 (1):1-17.
    BackgroundOne of the next frontiers in HIV research is focused on finding a cure. A new priority includes people with HIV with non-AIDS terminal illnesses who are willing to donate their bodies at the end-of-life to advance the search towards an HIV cure. We endeavored to understand perceptions of this research and to identify ethical and practical considerations relevant to implementing it.MethodsWe conducted 20 in-depth interviews and 3 virtual focus groups among four types of key stakeholders in the United States (...)
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  6.  21
    Debating Ethics in HIV Research: Gaps Between Policy and Practice in Nigeria.Morenike Oluwatoyin Folayan, Kristin Peterson, Bridget Haire, Brandon Brown, Kadiri Audu, Olumide Makanjuola, Babatunde Pelemo & Vicki Marsh - 2015 - Developing World Bioethics 15 (3):214-225.
    HIV prevention is a critical health issue in Nigeria; a country that has one of the worst HIV epidemic profiles in the world. With 270,000 new infections in 2012, Nigeria is a prime site for HIV prevention research. One effect of the HIV epidemic has been to revolutionalise ethical norms for the conduct of research: it is now considered unethical to design and implement HIV related studies without community engagement. Unfortunately, there is very little commensurate effort in building the capacity (...)
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  7.  9
    Peruvian Female Sex Workers’ Ethical Perspectives on Their Participation in an HPV Vaccine Clinical Trial.Brandon Brown, Mariam Davtyan & Celia B. Fisher - 2015 - Ethics and Behavior 25 (2):115-128.
    This study examined female sex workers’ evaluation of ethically relevant experiences of participating in an HPV4 vaccine clinical trial conducted in Lima, Peru. The Sunflower Study provided all participants with HPV testing, treatment for those testing positive, and access to the vaccine for all testing negative. Themes that emerged from content analysis of interviews with 16 former participants included the importance of respectful treatment and access to healthcare not otherwise available and concerns about privacy protections, the potential for HIV stigma, (...)
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  8.  1
    The Need to Track Payment Incentives to Participate in HIV Research.Brandon Brown, Jerome T. Galea, Karine Dubé, Peter Davidson, Kaveh Khoshnood, Lisa Holtzman, Logan Marg & Jeff Taylor - 2018 - IRB: Ethics & Human Research 40 (4):8-12.
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  9.  75
    Post-Approval Monitoring and Oversight of U.S.-Initiated Human Subjects Research in Resource-Constrained Countries.Brandon Brown, Janni Kinsler, Morenike O. Folayan, Karen Allen & Carlos F. Cáceres - 2014 - Journal of Bioethical Inquiry 11 (2):119-123.
    The history of human subjects research and controversial procedures in relation to it has helped form the field of bioethics. Ethically questionable elements may be identified during research design, research implementation, management at the study site, or actions by a study’s investigator or other staff. Post-approval monitoring (PAM) may prevent violations from occurring or enable their identification at an early stage. In U.S.-initiated human subjects research taking place in resource-constrained countries with limited development of research regulatory structures, arranging a site (...)
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  10.  23
    Ethical Issues in Adolescents' Sexual and Reproductive Health Research in Nigeria.Morenike Oluwatoyin Folayan, Bridget Haire, Abigail Harrison, Morolake Odetoyingbo, Olawunmi Fatusi & Brandon Brown - 2015 - Developing World Bioethics 15 (3):191-198.
    There is increasing interest in the need to address the ethical dilemmas related to the engagement of adolescents in sexual and reproductive health research. Research projects, including those that address issues related to STIs and HIV, adverse pregnancy outcomes, violence, and mental health, must be designed and implemented to address the needs of adolescents. Decisions on when an individual has adequate capacity to give consent for research most commonly use age as a surrogate rather than directly assessing capacity to understand (...)
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  11.  25
    Using the Ebola Outbreak as an Opportunity to Educate on Vaccine Utility.Brandon Brown - 2014 - Journal of Bioethical Inquiry 11 (4):415-416.
    The first domestic death from Ebola in the United States occurred in Texas in October 2014. Family members who were potentially exposed to the infected individual were legally and involuntarily quarantined. Quarantine may not be a recent normal practice in the United States, but it was used extensively during the influenza pandemic in the early 20th century. However, health care ethics comes into play when we quarantine someone whose infection status is unknown versus active. To prevent the spread of a (...)
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  12.  11
    HIV Prevention Research and COVID-19: Putting Ethics Guidance to the Test.Jeremy Sugarman, Steven Wakefield, Brandon Brown, Ernest Moseki, Robert Klitzman, Florencia Luna, Leah A. Schrumpf, Wairimu Chege & Stuart Rennie - 2021 - BMC Medical Ethics 22 (1):1-10.
    BackgroundCritical public health measures implemented to mitigate the spread of the novel coronavirus disease pandemic have disrupted health research worldwide, including HIV prevention research. While general guidance has been issued for the responsible conduct of research in these challenging circumstances, the contours of the dueling COVID-19 and HIV/aids pandemics raise some critical ethical issues for HIV prevention research. In this paper, we use the recently updated HIV Prevention Trials Network Ethics Guidance Document to situate and analyze key ethical challenges related (...)
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  13.  8
    Considerations for Stakeholder Engagement and COVID‐19 Related Clinical Trials’ Conduct in Sub‐Saharan Africa.Morenike Oluwatoyin Folayan, Brandon Brown, Bridget Haire, Chinedum Peace Babalola & Nicaise Ndembi - 2021 - Developing World Bioethics 21 (1):44-50.
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  14.  11
    “Money Helps”: People Who Inject Drugs and Their Perceptions of Financial Compensation and its Ethical Implications.Roberto Abadie, Brandon Brown & Celia B. Fisher - 2019 - Ethics and Behavior 29 (8):607-620.
    This study documents how people who inject drugs in rural Puerto Rico perceive payments for participating in HIV epidemiological studies. In-depth interviews were conducted among a subset of active PWID older than 18 years of age who had been previously enrolled in a much larger study. Findings suggest that financial compensation was the main motivation for initially enrolling in the parent study. Then, as trust in the researchers developed, participants came to perceive compensation as part of a reciprocal exchange in (...)
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  15.  5
    Relevant Academic Literature, Applicable Federal Regulations for the Protection of Human Subjects on Emergency Research Involving Artificial/Substitute Blood Products (Including PolyHeme).Brandon Brown - forthcoming - Indiana University Center for Bioethics.
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