The Diagnostic and Statistical Manual (DSM) of the American Psychiatric Association, currently in its fourth edition and considered the reference for the characterization and diagnosis of mental disorders, has undergone various developments since its inception in the mid-twentieth century. With the fifth edition of the DSM presently in field trials for release in 2013, there is renewed discussion and debate over the extent of its relative successes - and shortcomings - at iteratively incorporating scientific evidence on the often ambiguous nature (...) and etiology of mental illness. Given the power that the DSM has exerted both within psychiatry and society at large, this essay seeks to analyze variations in content and context of various editions of the DSM, address contributory influences and repercussion of such variations on the evolving landscape of psychiatry as discipline and practice over the past sixty years. Specifically, we document major modifications in the definition, characterization, and classification of mental disorders throughout successive editions of the DSM, in light of shifting trends in the conceptualization of psychopathology within evolving schools of thought in psychiatry, and in the context of progress in behavioral and psychopharmacological therapeutics over time. We touch upon the social, political, and financial environments in which these changes took places, address the significance of these changes with respect to the legitimacy (and legitimization) of what constitutes mental illness and health, and examine the impact and implications of these changes on psychiatric practice, research, and teaching. We argue that problematic issues in psychiatry, arguably reflecting the large-scale adoption of the DSM, may be linked to difficulties in formulating a standardized nosology of psychopathology. In this light, we highlight 1) issues relating to attempts to align the DSM with the medical model, with regard to increasing specificity in the characterization of discrete mental disease entities and the incorporation of neurogenetic, neurochemical and neuroimaging data in its nosological framework; 2) controversies surrounding the medicalization of cognition, emotion, and behavior, and the interpretation of subjective variables as 'normal' or 'abnormal' in the context of society and culture; and 3) what constitutes treatment, enablement, or enhancement - and what metrics, guidelines, and policies may need to be established to clarify such criteria. (shrink)

In 1980, Ronald Reagan was elected President, and the conservative revolution emerged. Who provoked this revolution? Author Shadia Drury provides a fascinating answer to the question, as she looks at the work of Leo Strauss, a German Jewish emigre and scholar, who was one of the most influential individuals in the conservative movement. Among his disciples are Chief Justice Clarence Thomas and Speaker of the House Newt Gingrich.

In 1980, Ronald Reagan was elected President of the United States for his first term and the conservative revolution that was slowly developing in the United States finally emerged in full-throated roar. Who provoked the conservative revolution? Shadia Drury provides a fascinating answer to the question as she looks at the work of Leo Strauss, a seemingly reclusive German Jewish emigré and scholar, who was one of the most influential individuals in the conservative movement, a man widely seen as (...) the godfather of the Republican party’s failed “Contract With America.” Among his students were individuals such as Alan Bloom, author of The Closing of the American Mind. Strauss influenced the work of Irving Kristol, Gertrude Himmelfarb and William Kristol, as well as Chief Justice Clarence Thomas and Speaker of the House Newt Gingrich. Drury delves deeply into Strauss’s work at the University of Chicago where he taught his students that, if they truly loved America, they must save her from her fateful enchantment with liberalism. Leo Strauss and the American Right is a fascinating piece of work that anyone interested in understanding our current political situation will want to read. (shrink)

The COVID-19 Vaccines Global Access Facility represents an unprecedented global collaboration facilitating the development and distribution of vaccines for COVID-19. COVAX pools and channels funds from state and non-state actors to promising vaccine candidates, and has started to distribute successful candidates to participating states. The WHO, one of the leaders of COVAX, recognised vaccine doses would initially be scarce, and therefore, prepared a two-staged allocation mechanism they considered fair. In the first stage, vaccine doses are distributed equally among participating countries, (...) while in the second stage vaccine doses will be allocated according to a country’s need. Ethicists have questioned whether this is the fairest distribution—they argue a country’s need should be taken into account from the start and correspondingly, have proposed a framework that treats individuals with equal moral concern, aims to minimise harm and gives priority to the worst-off. In this paper, we seek to explore these concerns by comparing COVAX’s allocation mechanism to a targeted allocation based on need. We consider which distribution would more likely maximise well-being and align with principles of equity. We conclude that although in theory, a targeted distribution in proportion to a country’s need would be more morally justifiable, when political realities are taken into account, an equal distribution seems more likely to avert a greater number of deaths and reduce disparities. (shrink)

We show that for an uncountable κ in a suitable Cohen real model for any family {A ν } ν<κ of sets of reals there is a σ-homomorphism h from the σ-algebra generated by Borel sets and the sets A ν into the algebra of Baire subsets of 2 κ modulo meager sets such that for all Borel B, B is meager iff h(B) = 0. The proof is uniform, works also for random reals and the Lebesgue measure, and in (...) this way generalizes previous results of Carlson and Solovay for the Lebesgue measure and of Kamburelis and Zakrzewski for the Baire property. (shrink)

a relatively more sympathetic attitude among younger judges, many of them women, and among trainees, may reflect a historical evoluti.

The purpose of this study was to compare exploratory behaviours in children with autism and typically developing preschool children and the course of their adaptation to novelty. A series of five repeated trials was conducted, during which children were allowed to freely explore the experimental room. The results revealed differences between study groups in the overall rate of exploratory activity, which was lower in children with autism. Patterns of time characteristics of exploratory activity showed both similarities and differences between the (...) groups. In both groups, the rate of simple exploratory behaviours decreased with time, while the levels of diversive exploration increased. Children with autism engaged in less complex object manipulation than their peers. Similarly, their adaptation and habituation to a novel environment proceeded in a different way in the low stimulation zone than in the high stimulation zone. In the low and medium stimulation zones, the rate of exploration decreased with time, while in the high stimulation zone it remained relatively constant. In typically developing children, habituation occurred in all stimulation zones. These results suggest the presence of some differences between the patterns of adaptation to novelty in the two groups, which emerge in a stimulation-rich environment. Due to the limitations of the study, in particular the small number of subjects, the present paper should be treated as a preliminary report. (shrink)

ABSTRACT In Mexico informed consent is a legal requirement that ensures that patients who are invited to participate in clinical trials are provided with all the information needed to decide whether to participate, or not, in a research protocol. To improve our understanding of the problems physicians in developing countries encounter, when obtaining informed consent (IC), we examined their opinion on the importance of IC in clinical research, the quantity and quality of the information provided to the participant, and the (...) conditions in which the IC is obtained. Investigators considered that IC was useful to the patients, providing information that helped the patient to make a decision about his/her participation. Nevertheless, they felt that for some aspects of the research, like drug development in general, the use of placebos, and the randomization process, many of the patients were not capable of fully understanding the information provided, referring to the complexity of the information and illiteracy as the main reasons. Many investigators were not acquainted with some of the guidelines established in the Mexican General Law of Health,1 36% of them admitting to not having completed their IC letters. Most investigators gave only minutes to the patient to make a decision and 20% of ICs were obtained while the patient was hospitalized. Except for one investigator, all of them considered that specific training in medical ethics would be useful for the daily clinical work. (shrink)

Religion is among the determinants of human beliefs and values in various societies, shaping people’s behaviours in a range of life aspects, including the workplace. In view of the influence of religion in Malaysia, this issue becomes highly significant. With regard to the profound impact of religion on creating individual and collective behaviours, the present study aims to investigate the effects of religious behaviours (RBs) on organisational commitment (OC) among Malaysian healthcare workers (HCWs) in 2022, by a survey method implemented (...) using standardised questionnaires for data collection. The statistical population comprised of 2500 HCWs from 10 hospitals in Kuala Lumpur, Georgetown and Malacca, Malaysia, selected by the simple random sampling among the Muslim staff. The data analysis was further fulfilled using the AMOS software package for structural equation modelling (SEM). In general, the study results demonstrated a significant and positive relationship between RBs and OC among Malaysian HCWs (p-value = 0.84, t-statistic = 6.50).Contribution: As demonstrated by the study results, it is possible to inspire OC among employees through strengthening RBs and take advantages of the results. Thus, RBs shown by employees can definitely bring positive results to organisations; therefore, OC in Malaysian HCWs improves. (shrink)

Alexandre Kojve (1902-1968) was Hegel's most famous interpreter, reading Hegel through the eyes of Marx and Heidegger simultaneously. The result was a wild if not hypnotic mlange of ideas. In this book, Drury reveals the nature of Kojve's Hegelianism and the extraordinary influence it has had on French postmodernists on the left (Raymond Queneau, Georges Bataille, and Michel Foucault) and American postmodernists on the right (Leo Strauss, Allan Bloom, and Francis Fukuyama). According to Drury, Kojve followed Hegel in thinking that (...) reason has triumphed in the course of history, but it is a cold, soulless, instrumental, and uninspired rationalism that has conquered and disenchanted the world. Drury maintains that Kojve's conception of modernity as the fateful triumph of this arid rationality is the cornerstone of postmodern thought. Kojve's picture of the world gives birth to a dark romanticism that manifests itself in a profound nostalgia for what reason has banished - myth, madness, disorder, spontaneity, instinct, passion, and virility. In Drury's view, these ideas romanticize the gratuitous violence and irrationalism that characterize the postmodern world. (shrink)

In this startling book, Drury overturns the long-standing reputation of Thomas Aquinas as the most moderate and rational exponent of the Christian faith. She reveals Aquinas to be one of the most zealous Dominicans or Hounds of the Lord—an ardent defender of papal supremacy, the Inquisition, and the persecution of Jews. Despite her unstinting criticism, Drury sets out to retrieve the rationalism and naturalism that Aquinas failed to reconcile with his faith.

This collection by some of the leading scholars of Strauss's work is the first devoted to Strauss's thought regarding education. It seeks to address his conception of education as it applies to a range of his most important concepts, such as his views on the importance of revelation, his critique of modern democracy and the importance of modern classical education.

This book poses a radical challenge to the legend of Socrates bequeathed by Plato and echoed by scholars through the ages: that Socrates was an innocent sage convicted and sentenced to death by the democratic mob, merely for merely questioning the political and religious ideas of his time. This legend conceals an enigma: How could a sage who was pious and good be so closely associated with the treasonous Alcibiades, who betrayed Athens in the Peloponnesian war? How could Critias and (...) Charmides, who launched a reign of terror in Athens after her defeat, have been among his students and closest associates? The book makes the case for the prosecution, denouncing the religion of Socrates for inciting a radical politics of absolutism and monism that continues to plague Western civilization. It is time to recognize that Socrates was no liberator of the mind, but quite the contrary-he was the architect of a frightful authoritarianism, which continues to manifest itself, not only in Islamic terror, but also in liberal foreign policy. Defending Homer and the tragic poets, the book concludes that the West has imbibed from the wrong Greeks. (shrink)

The purpose of this paper is to show that the ‘simple natures’ which appear in the Regulae are those very ‘modes’ and ‘attributes’ of ‘substance’ which appear in all of Descartes’ later works. Contrary to the opinions of some critics, I hope to show that simple natures were not discarded by Descartes for being inconsistent with his later philosophy; that is, if they were discarded at all! I also hope to show that simple natures do not have such a “wide (...) berth” that they are inadequate in dealing with Descartes’ “mature philosophy”. On the contrary, I hope to make it sufficiently clear that they are indispensable for our understanding of the relationship between his epistemology and ontology.Descartes’ account of ‘simple natures’ is of utmost importance to his epistemology. His account of ‘substance’ constitutes the very essence of his ontology. We shall see that while ‘simple natures’ are all we can know, ‘ substance’ is all that exists. Hence the relationship of simple natures to substance should aid us in understanding the relationship of thought to being. This relationship serves to illustrate the correspondence between knowledge and existence which is the hallmark of Cartesian thought. (shrink)