Viruses and related infectious genetic parasites are the most abundant biological agents on this planet. They invade all cellular organisms, are key agents in the generation of adaptive and innate immune systems, and drive nearly all regulatory processes within living cells.

La “referencia al origen es un invariante cultural” . Sin embargo, cada país tiene modos particulares de procesar su propia historia. Este trabajo analiza una de las modalidades en que –en Argentina– se narra ese origen, en el contexto de los bicentenarios latinoamericanos. Ese momento originario –la Revolución de Mayo de 1810– aparece representado en producciones literarias que han sido best sellers de historia. Esos relatos de no-ficción junto a otros de ficción permiten problematizar la cuestión del género y su (...) relación con “la nación” como matriz cultural. Un modo de imaginar un “nosotros” y de permitir ciertas inclusiones y exclusiones identitarias en el momento del origen y en el presente del Bicentenario. (shrink)

ABSTRACTIn the process of teaching law, is necessary to address some aspects that are not framed in strictly legal knowledge and require different strategies to be approach by the professor. An exa...

This study presents a web-based sentence comprehension test aimed at identifying high school students who are at risk for a language delay. By assessing linguistic skills on a sample of high school students with Italian as an L2 and their monolingual peers, attending a vocational school, we were able to identify a subgroup of L2 students with consistent difficulties in sentence comprehension, though their reading skills were within the average range. The same subgroup revealed to experience a lack of support (...) within the school context, suggesting that poor L2 skills might be a critical variable to consider in order to identify students at risk for school exclusion. Regarding the test, accuracy to the on-line sentence comprehension task was significantly predicted by reading abilities and vocabulary skills, thus indicating that this test might represent a rapid but efficient way to assess linguistic abilities at school. We recommend that establishing a valid and practical procedure for the evaluation of linguistic skills in bilingual students who struggle with their L2 is the first step towards promoting social inclusion in the multilingual classroom, in order to increase their ability to actively participate in school and social activities. (shrink)

Decisions in the environmental and in particular the climate domain are burdened with uncertainty. Here, we focus on uncertainties faced by individuals when making decisions about environmental behavior, and we use the statistical sampling framework to develop a classification of different sources of uncertainty they encounter. We then map these sources to different public policy strategies aiming to help individuals cope with uncertainty when making environmental decisions.

La significación del espacio como construcción subjetiva y como subjetivadora y su aplicación al aula escolar y a la escuela.

À la fin du xixe siècle, la plupart des nations latino-américaines étaient intégrées au commerce international par l’exportation de produits agricoles, miniers ou d’élevage et l’importation de biens manufacturés. Le développement des moyens de transport, principalement le train, et le processus d’urbanisation s’étaient accélérés. De nombreuses villes surgirent, de grandes villes furent transformées et embellies par de nouveaux bâtiments, parcs et jardins. La demande de main d’œuvre impulsa un...

Doing phenomenological research entails a complex process that is only minimally published in scientific journals. What is often missing reflects how being in research calls into question the researchers themselves. Anyone who has conducted qualitative empirical research knows that personal engagement does not come at no cost; there are multiple pedagogical and professional practice gains. This article’s aim is to share the phenomenology behind phenomenology: the reflection and personal experience of doing/being in phenomenological research and the personal narrative of what (...) this experience has meant concerning the authors' own context: health care and nursing. Taking advantage of a conducted research exploring the lived experience of family caregivers of hematological patients assisted at home, we propose considerations about the perceived epistemic and cognitive gains, the formative and personal/professional sequels of having been reflective participants of phenomenologically oriented research. (shrink)

En medio de una época donde la incertidumbre, la inseguridad y la desprotección crecen, la teoría de la hegemonía, elaborada por Gramsci y reformulada por E. Laclau y Ch. Mouffe, constituye un punto nodal para pensar la política. Esta categoría surge como respuesta a una crisis que pone en cuestión las concepciones tradicionales para explicar la contingencia de las formas históricas concretas. La sociedad no debe ser entendida como un espacio cerrado sino como una estructura, resultado de prácticas articulatorias que (...) organizan y constituyen las relaciones sociales. La hegemonía, entonces, entendida como articulación contingente de elementos en torno a las luchas de los agentes sociales concretos, configura una valiosa herramienta teórica para reflexionar acerca de nuestra compleja realidad. (shrink)

Recent investigations surprisingly indicate that single RNA "stem-loops" operate solely by chemical laws that act without selective forces, and in contrast, self-ligated consortia of RNA stem-loops operate by biological selection. To understand consortial RNA selection, the concept of single quasi-species and its mutant spectra as drivers of RNA variation and evolution is rethought here. Instead, we evaluate the current RNA world scenario in which consortia of cooperating RNA stem-loops are the basic players. We thus redefine quasispecies as RNA quasispecies consortia (...) and argue that it has essential behavioral motifs that are relevant to the inherent variation, evolution and diversity in biology. We propose that qs-c is an especially innovative force. We apply qs-c thinking to RNA stem-loops and evaluate how it yields altered bulges and loops in the stem-loop regions, not as errors, but as a natural capability to generate diversity. This basic competence-not error-opens a variety of combinatorial possibilities which may alter and create new biological interactions, identities and newly emerged self identity functions. Thus RNA stem-loops typically operate as cooperative modules, like members of social groups. From such qs-c of stem-loop groups we can trace a variety of RNA secondary structures such as ribozymes, viroids, viruses, mobile genetic elements as abundant infection derived agents that provide the stem-loop societies of small and long non-coding RNAs. (shrink)

La presente investigación aborda el estudio de las transformaciones producidas en el paisaje del poblado de Puerto Morelos, Quintana Roo, por la incorporación de la actividad turística en la vida cotidiana de sus pobladores. A medida que los objetos, usos y el lenguaje del turismo se incorporan a las costumbres, tradiciones, relaciones sociales y estilos de vida de la población; los espacios de vida -laboral, vecinal, doméstico y de ocio- adquieren características físicas poco tradicionales y formas excluyentes de aprovechamiento que (...) contribuyen a configurar y fortalecer paisajes funcionales al capital turístico. La propiedad privada y el mercado de tierras, las políticas para la conservación de los recursos naturales, la deslocalización empresarial, la imagen turística y las oleadas migratorias son factores que han permitido la reorganización de los espacios de vida y, por consiguiente, la configuración de diversos paisajes turísticos a lo largo de la costa. (shrink)

Cognitive science has been traditionally organized around the individual as the basic unit of cognition. Despite developments in areas such as communication, human–machine interaction, group behavior, and community organization, the individual-centric approach heavily dominates both cognitive research and its application. A promising direction for cognitive science is the study of augmented intelligence, or the way social and technological systems interact with and extend individual cognition. The cognitive science of augmented intelligence holds promise in helping society tackle major real-world challenges that (...) can only be discovered and solved by teams made of individuals and machines with complementary skills who can productively collaborate with each other. (shrink)

This study conforms an essay, in the terms of an investigation of a faculty subject at University, on the usage of exploratory methods of multivaried analysis. The exercise consists in conforming a regionalisation of subprovincial areas according to their level of social development. In order to ac..

We comment on the limits of relying on prior literature when constructing the design space for an integrative experiment; the adaptive nature of social and behavioral phenomena and the implications for the use of theory and modeling when constructing the design space; and on the challenges of measuring random errors and lab-related biases in measurement without replication.

Desde los remotos tiempos de la tragedia Ática en Grecia, el teatro es y ha sido siempre movimiento, siendo este una característica esencial de los seres orgánicos, es decir, de los dotados de vida. No obstante, se corre el riesgo de reemplazar su mecánica natural con metafísica, cuando ello no es coherente ni siquiera en hipótesis. Cabe demostrar las disimilitudes del teatro con las doctrinas escolásticas, idealistas, o hinduistas, y su compatibilidad con los átomos, electrones y las leyes de la (...) física, sometiendo sus conceptos al rigor epistemológico. La creación artística nace del psiquismo humano, aun no siendo material en primera instancia, pero ya luego cobra su forma cualitativa definitiva. Para ello atraviesa por varios tipos de censura, tanto física como psicológica, buscando expresarse mediante el lenguaje en que se comunican los distintos géneros dramáticos, dando a conocer su situación de crisis sin retorno, esa que se debate entre crueldad y violencia. Antonin Artaud intrinca al teatro las ideas cabalísticas y no busca contrastarlas con argumentación lógica. La evidencia demuestra que, si es que hay una unidad, esa es la del teatro con lo físico. Lo físico es su verdadero “doble”. Un sucinto pero conciso repaso histórico, bien prodigado de documentación y basado en los preceptos erigidos por el materialismo dialectico, nos dará la certeza de que el teatro pertenece exclusivamente al mundo físico, no solo en la práctica, sino también en esencia, y esta es la materia, siendo solo la metafísica un estadio improbable dentro de ella. (shrink)

Individual differences in demographics, personality, and other related beliefs are associated with coronavirus disease 2019 threat beliefs. However, the relative contributions of these different types of individual differences to COVID-19 threat beliefs are not known. In this study, a total of 1,700 participants in Croatia completed a survey that included questions about COVID-19 risks, questions about related beliefs including vaccination beliefs, trust in the health system, trust in scientists, and trust in the political system, the HEXACO 60 personality inventory, as (...) well as demographic questions about gender, age, chronic diseases, and region. We used hierarchical regression analyses to examine the proportion of variance explained by demographics, personality, and other related beliefs. All three types of individual differences explained a part of the variance of COVID-19 threat beliefs, with related beliefs explaining the largest part. Personality facets explained a slightly larger amount of variance than personality factors. These results have implications for communication about COVID-19. (shrink)

Objective: Traditionally, asymmetric spatial processing has been assessed with paper-and-pencil tasks, but growing evidence indicates that computer-based methods are a more sensitive assessment modality. It is not known, however, whether simply converting well-established paper-and-pencil methods into a digital format is the best option. The aim of the present study was to compare sensitivity in detecting contralesional omissions of two different computer-based methods: a “digitally converted” cancellation task was compared with a computer-based Visual and Auditory dual-tasking approach, which has already proved (...) to be very sensitive.Methods: Participants included 40 patients with chronic unilateral stroke in either the right hemisphere or the left hemisphere and 20 age-matched healthy controls. The cancellation task was implemented on a very large format or in a smaller paper-and-pencil version. The computer-based dual-tasks were implemented on a 15′′ monitor and required the detection of unilateral and bilateral briefly presented lateralized targets.Results: Neither version of the cancellation task was able to show spatial bias in RH patients. In contrast, in the Visual dual-task RH patients missed significantly more left-sided targets than controls in both unilateral and bilateral trials. They also missed significantly more left-sided than right-sided targets only in the bilateral trials of the Auditory dual-task.Conclusion: The dual-task setting outperforms the cancellation task approach even when the latter is implemented on a screen. Attentionally demanding methods are useful for revealing mild forms of contralesional visuospatial deficits. (shrink)

For the authors' responses to comments similar to those expressed here by Balsam & Drew, please see: M. Domjan, B. Cusato, & R. Villarreal (2000). Extensions, elaborations, and explanations of the role of evolution and learning in the control of social behavior. BBS 23(2):269–82. [Authors' Response to first round of commentary.].

Adolescence is the period of growth between childhood and adulthood. This period of development, which goes from 13 to 18 years, is usually presented as critical, due to the profound modifications of physiological and psychological order in this research we worked with a sample of 60 students, from Secondary School No. 8, morning and evening shift. An instrument was made with 45 variables, 5 of them signalytic: age, gender, an average of the previous cycle, performing some extracurricular activity, and shift. (...) The information was processed in the SPSS and STATISTIC programs. The conclusions showed that the student, by showing a need to learn, is able to develop different academic skills through different factors, such as motivation, thus improving their school performance. Thus proposes the development of an intervention model, for training teachers, on motivation methods in the classroom; As well as conferences on the importance of the topic of adolescent motivation and the factors involved in improving academic performance, teachers and parents will be taught and publicity will be developed on the importance of school motivation in adolescents and how it intervenes from home, at school and how this influences academic results. (shrink)

Reactions to the target article included requests for extensions and elaborations of the schema we proposed and discussions of apparent shortcomings of our approach. In general, we welcome suggestions for extension of the schema to additional kinds of social behavior and to forms of learning other than Pavlovian conditioning. Many of the requested elaborations of the schema are consistent with our approach, but some may limit its generality. Many of the apparent shortcomings that commentators discussed do not seem problematic. Our (...) schema encourages a broad view of the behavioral consequences of Pavlovian conditioning – including learned modifications of responding to the unconditioned stimulus. Costs and benefits addressed by our schema are the long-range reproductive consequences of learning – not the immediate reinforcing consequences of particular conditioned responses. Our approach allows the evolution of learning to yield maladaptive behavior and can be extended to characterize dynamic social interactions. We clarify that ours is not a homeostatic model involving ideal set points, and we clarify and defend our application of Pavlovian concepts to the analysis of social play. (shrink)

The conceptual and investigative tools for the analysis of social behavior can be expanded by integrating biological theory, control systems theory, and Pavlovian conditioning. Biological theory has focused on the costs and benefits of social behavior from ecological and evolutionary perspectives. In contrast, control systems theory is concerned with how machines achieve a particular goal or purpose. The accurate operation of a system often requires feed-forward mechanisms that adjust system performance in anticipation of future inputs. Pavlovian conditioning is ideally suited (...) to subserve this function in behavioral systems. Pavlovian mechanisms have been demonstrated in various aspects of sexual behavior, maternal lactation, and infant suckling. Pavlovian conditioning of agonistic behavior has been also reported, and Pavlovian processes may likewise be involved in social play and social grooming. Several further lines of evidence indicate that Pavlovian conditioning can increase the efficiency and effectiveness of social interactions, thereby improving their cost/benefit ratio. We extend Pavlovian concepts beyond the traditional domain of discrete secretory and other physiological reflexes to complex real-world behavioral interactions and apply abstract laboratory analyses of the mechanisms of associative learning to the daily challenges animals face as they interact with one another in their natural environments. Key Words: aggression; biological theory; control theory; feed-forward mechanisms; learning theory; nursing and lactation; Pavlovian conditioning; sexual behavior; social behavior; social grooming; social play. (shrink)

This document describes the technique and technology currently used to apply cryosurgery, a technic based on low temperatures for medical purposes that allows the controlled destruction of pathological cells and tissues. Cryosurgery is an effective and innocuous process that is painless, safe and economical, applied to multiple specialities in which it provides alternatives to its traditional methods. A search was carried out for articles and bibliographic reviews referring to Cryosurgery and from whose information this technical note was obtained. Research on (...) the application of Cryosurgery presents solid evidence of its benefits. Therefore, it has been used in several countries and health campaigns, showing excellent results, so it is advisable to implement it in health systems. (shrink)