私たちの現実をこのようなものたらしめている「生命」。生命の内に何か新たなものが姿を現わす可能性としての「自由」。この二つの視点から捉えることで、私たちの現実が成り立っているさまを厳密に、かつ精密に描き 出す。現象学に立脚しながら、心の哲学、西田幾多郎の思想、現代の生命科学...などをめぐって展開する、スリリングで強靱な思考。.

哲学者・井筒俊彦が見極めた「東洋」哲学とは何か。端的な「ある」とは何か、またその先に開いている「無」を思考することとは?

Replication forks inevitably stall at damaged DNA in every cell cycle. The ability to overcome DNA lesions is an essential feature of the replication machinery. A variety of specialized polymerases have recently been discovered, which enable cells to replicate past various forms of damage by a process termed translesion synthesis. Alternatively, homologous recombination can be used to restart DNA replication across the lesion. Genetic and biochemical studies have shed light on the impact of these two post‐replication repair pathways in bacteria (...) and yeast. In vertebrates, however, a genetic approach to study post‐replication repair has been compromised because many of the genes involved appear to be essential for embryonic development. We have taken advantage of the chicken cell line DT40 to perform a genetic analysis of translesion synthesis and homologous recombination and to characterize genetic interactions between these two pathways in vertebrates. In this article, we aim to summarize our current understanding of post‐replication repair in DT40 in the perspective of bacterial, yeast and mammalian genetics. BioEssays 26:151–158, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Most previous research has demonstrated that receiving ability-focused praise negatively affects intrinsic motivation following failure. Surprisingly, a recent study showed that ability-focused praise affects not only the praisee but also the person offering praise, that is, the praiser. However, evidence of the effects on the praiser is quite limited, despite the utility of praise in education. Therefore, the present study employed face-to-face interaction to advance the knowledge of the effects of praise on the praiser. Two experiments were conducted in which (...) undergraduate participants praised a research confederate. We measured attentional engagement using an eye-tracker as a behavioral indicator of intrinsic motivation, as well as self-reported task enjoyment. To estimate the effect of praise, we combined the results of two experiments and conducted a Bayes factor meta-analysis. The results showed that in the ability praise group, participants’ attentional engagement in a task was significantly lower than in the control group. The present finding indicates that ability-focused praise negatively affects the praiser’s intrinsic motivation and suggests that praise should be used with caution in social and educational contexts. (shrink)

A psycho-historical framework for the science of art appreciation will be an experimental discipline that may shed new light on the highest capacities of the human brain, yielding new scientific ways to talk about the art appreciation. The recent findings of the contextual information processing in the human brain make the concept of the art-historical context clear for empirical experimentation.

The masked priming paradigm has been extensively used to investigate the indirect impacts of unconscious stimuli on conscious behaviors, and the congruency effect of priming on free choices has gained increasing attention. Free choices allow participants to voluntarily choose a response from multiple options during each trial. While repeated practice is known to increase priming effects in subliminal visual tasks, whether practice increases the priming effect of free choices in the masked priming paradigm is unclear. And it is also not (...) clear how the proportions of free choice and forced choice trials in one block will affect the free choice masked priming effect. The present study applied repeated practice in the masked priming paradigm and found that after training, the participants were more likely to be influenced by masked primes during free choice, but this training process did not alter the visibility of masked stimuli. In addition, this study revealed that when the proportions of free choice and forced choice trials were equal during the training stage, this enhanced effect by practice was the strongest. These results indicated that practice could enhance masked stimulus processing in free-choice, and that the learning effect may mainly be derived from the early selection and integrated processing of masked stimuli. (shrink)

Researchers have suggested that infants exhibiting baby schema are considered cute. These similar studies have mainly focused on changes in overall baby schema facial features. However, whether a change in only eye size affects the perception of cuteness across different facial expressions and ages has not been explicitly evaluated until now. In the present study, a paired comparison method and 7-point scale were used to investigate the effects of eye size on perceived cuteness across facial expressions and ages. The results (...) show that stimuli with large eyes were perceived to be cuter than both unmanipulated eyes and small eyes across all facial expressions and age groups. This suggests not only that the effect of baby schema on cuteness is based on changes in a set of features but also that eye size as an individual feature can affect the perception of cuteness. (shrink)

Friedrich Nietzsche's work has had a significant impact on the intellectual life of non-Western cultures and elicited responses from important thinkers outside of the Anglo-American philosophical traditions as well. Bringing together thirteen internationally renowned scholars, this is the first collection of essays to address the connection between Nietzsche's ideas and philosphies in India, China, and Japan. The contributors are Roger T. Ames, Johann Figl, Chen Guying, Michel Hulin, Arifuku Kogaku, David A. Kelly, Glen T. Martin, Sonoda Muneto, Graham Parkes, (...) okochi Ryogi, Eberhard Scheiffele, Mervyn Sprung, and Joan Stambaugh. "Exemplary. Its comparative approach is incisive yet accessible. I consider it a 'must read'"—Kathleen Marie Higgins, _Philosophy East and West_ "An excellent introduction to the broad ranging reception of Nietzsche among Asian thinkers."—James R. Watson, _Canadian Philosophical Review_ "The essays in this welcome collection are invariably thought-provoking and genuinely cross-disciplinary."—Kenneth Surin, _Religious Studies Review_ "A worthy and undogmatic introduction to several fascinating questions concerning the relations between Nietzschean thought and certain traditions of thought in India, China, and Japan."—Don Miller, _Asian Studies Review_. (shrink)