A sense of agency (SoA) is the experience of subjective awareness regarding the control of one’s actions. Humans have a natural tendency to generate prediction models of the environment and adapt their models according to changes in the environment. The SoA is associated with the degree of the adaptation of the prediction models, e.g., insufficient adaptation causes low predictability and lowers the SoA over the environment. Thus, identifying the mechanisms behind the adaptation process of a prediction model related to the (...) SoA is essential for understanding the generative process of the SoA. In the first half of the current study, we constructed a mathematical model in which the SoA represents a likelihood value for a given observation (sensory feedback) in a prediction model of the environment and in which the prediction model is updated according to the likelihood value. From our mathematical model, we theoretically derived a testable hypothesis that the prediction model is updated according to a Bayesian rule or a stochastic gradient. In the second half of our study, we focused on the experimental examination of this hypothesis. In our experiment, human subjects were repeatedly asked to observe a moving square on a computer screen and press a button after a beep sound. The button press resulted in an abrupt jump of the moving square on the screen. Experiencing the various stochastic time intervals between the action execution button-press) and the consequent event square jumping caused gradual changes in the subjects' degree of their SoA. By comparing the above theoretical hypothesis with the experimental results, we concluded that the update (adaptation) rule of the prediction model based on the SoA is better described by a Bayesian update than by a stochastic gradient descent. (shrink)

如来蔵思想、法華経、中観、唯識、日本仏教等、仏教思想の様々な問題に関する批判的研究23編(和文15編、英文8編)を収録。.

This paper presents an explanation for the breakdown of dominant party systems. In contrast to previous works that examine how ruling parties lose their dominant position as a result of interparty competition, this paper focuses on how they are undermined from within by factional conflict. Through an overview of dominant party systems in the postwar world, we show that most of the ruling parties suffered from major splits that significantly reduced their electoral strengths before their final electoral defeat. In order (...) to explain why large groups of politicians decide to leave dominant parties that are likely to remain in power, we develop simple game-theoretic models of intraparty bargaining between party factions over the distribution of benefits from office. Our results suggest two mechanisms through which dominant parties break up. First, factional defections from dominant parties are likely to occur when they are experiencing a significant decline in public support. Second, factional defections are likely to occur when a non-mainstream faction is rapidly losing its bargaining power against the party leadership. Importantly, our results show that under certain conditions, dominant parties will break up even when their electoral prospects are much better than the opposition. We briefly discuss how these mechanisms can be applied to actual cases of dominant party systems. (shrink)

Representational momentum is a well-known phenomenon that occurs when a moving object vanishes suddenly and the memory of its final or vanishing position is displaced forward in the direction of its motion. Many studies have shown evidence of various perceptual and cognitive characteristics of RM in various daily aspects, sports, development, and aging. Here we examined the longitudinal developmental changes in the displacement magnitudes of RM among younger and older nursery school children for pointing and judging tasks. In our experiments, (...) the children were asked to point at by their finger and judge the spatial location of the vanishing point of a moving stimulus. Our results showed that the mean magnitudes of RM significantly decreased from 5- to 6-year-old children for the pointing and judging tasks, although the mean magnitude of RM was significantly greater in the 5-year-old children for the pointing task but not for the judging task. We further examined the developmental changes in RM for a wide range of ages based on data from the present study and our previous study. This ad hoc examination showed that the magnitude of RM was significantly greater in 5-year-old children than in adults for the pointing and judging tasks. Our findings suggest that the magnitude of RM was significantly greater in young children than in adults and significantly decreased in young children through adults for the pointing and judging tasks. (shrink)

We investigated whether the inferior parietal lobule (IPL) responds in real-time to multisensory inconsistency during movement. The IPL is thought to be involved in both the detection of inconsistencies in multisensory information obtained during movement and that obtained during self-other discrimination. However, because of the limited temporal resolution of conventional neuroimaging techniques, it is difficult to distinguish IPL activity during movement from that during self-other discrimination. We simultaneously conducted electroencephalography (EEG) and near-infrared spectroscopy (NIRS) with the goal of examining IPL (...) activity with a high spatiotemporal resolution during single reaching movements. Under a visual feedback-delay condition, gamma event-related synchronization (γ-ERS), i.e., an increase in gamma (31–47 Hz) EEG power, occurred during reaching movements. This γ-ERS is considered to reflect processing of information about prediction errors. To integrate this temporal information with spatial information from the NIRS signals, we developed a new analysis technique that enabled estimation of the regions that show a hemodynamic response characterized by EEG fluctuation present in the visual feedback-delay condition. As a result, IPL activity was explained by γ-ERS specific to visual feedback delay during movements. Thus, we succeeded in demonstrating real-time activation of the IPL in response to multisensory inconsistency. However, we did not find any correlation between either IPL activity or γ-ERS with the sense of agency. Therefore, our results suggest that while the IPL is influenced by prediction error signals, it does not engage in direct processing underlying the conscious experience of making a movement, which is the foundation of self-other discrimination. (shrink)

Recently we proposed the linguistic Copenhagen interpretation of quantum mechanics, which is called quantum language or measurement theory. This theory is valid for both quantum and classical systems. Thus, we think that quantum language is one of the most powerful scientific theories, like statistics, and thus, it is the scientific completion (i.e., the destination) of dualistic idealism. If so, we can introduce the concept “progress” in the dualistic idealism. For example, we can assert that [Plato → Descartes → Kant → (...) Wittgenstein → quantum language], where [“X” → “Y”] means that “Y” is more like quantum language than “X”. In this paper, we will study the problem of universals from the perspective of quantum language (i.e., from the scientific perspective of ignoring any religious perspective). And we can be confident of the progress of both of the two time series [Plato → Anselmus → Thomas Aquinas → quantum language] and [Descartes → Thomas Aquinas → quantum language] in dualistic idealism. The reader may find it surprising that Scholastic philosophy is more scientific than Cartesian-Kantian philosophy. However, this is because Descartes gave up the pursuit of “universals” and presented dualism as a visible “mind-matter dualism” so that it could be familiar to the general public. This made the Cartesian-Kantian philosophy socially successful, but unscientific. The problem of universals has not always been clear in the long history of philosophy. The reader should be convinced that the reason is that the problem of universals has been discussed in an incomplete non-scientific dualism to this day. (shrink)

Recently we proposed "quantum language" (or, the linguistic Copenhagen interpretation of quantum mechanics"), which was not only characterized as the metaphysical and linguistic turn of quantum mechanics but also the linguistic turn of Descartes=Kant epistemology. We believe that quantum language is the language to describe science, which is the final goal of dualistic idealism. Hence there is a reason to want to clarify, from the quantum linguistic point of view, the following problems: "brain in a vat argument", "the Cogito proposition", (...) "five-minute hypothesis", "only the present exists", "Copernican revolution", "McTaggart's paradox", and so on. In this paper, these will be discussed and clarified in quantum language. That is, these are not in quantum language. Also we emphasize that Leibniz's relationalism in Leibniz-Clarke correspondence is regarded as one of the most important parts of the linguistic Copenhagen interpretation of quantum mechanics. This paper is the revised version of the paper: Open Journal of Philosophy, 2018 Vol.8, No.5, 466-480). (shrink)

SUPERANNO A unique collection of photographs by WRA photographer Hikaru Iwasaki focuses on resettlement using photos of Japanese Americans following their release from WRA camps from 1943 to 1945. Author Lane Hirabayashi explores the use of photography in the WRA mission to encourage “loyal” Japanese Americans to return to society at large, and convince Euro-Americans this was safe. Hirabayashi also assesses the success of the WRA project, and the multiple uses of the photographs over time.

There is growing evidence that individuals with social anxiety show impaired cortisol recovery after experiencing social evaluative stressors. Yet, little is known regarding the cognitive processes underlying such impaired cortisol recovery. The present study examined the effect of post-event processing (PEP), referred to as repetitive thinking about social situations, on cortisol recovery following a social stressor. Forty-two non-clinical university students (23 women, 19 men, mean age = 22.0 ± 2.0 years) completed the Trier Social Stress Test (TSST), followed by a (...) thought sampling procedure which assessed the frequency of PEP reflecting the TSST. A growth curve model showed PEP and social anxiety interactively predicted cortisol recovery. In particular, PEP predicted impaired cortisol recovery in those with low levels of social anxiety but not in those with high levels of social anxiety, which contradicted the initial hypothesis. These findings suggest that PEP is differentially associated with cortisol recovery depending on levels of social anxiety. The possible mechanisms underlying these findings were discussed in terms of protective inhibition framework. (shrink)

To apply reinforcement learning to difficult classes such as real-environment learning, we need to use a method robust to perceptual aliasing problem. The exploitation-oriented methods such as Profit Sharing can deal with the perceptual aliasing problem to a certain extent. However, when the agent needs to select different actions at the same sensory input, the learning efficiency worsens. To overcome the problem, several state partition methods using history information of state-action pairs are proposed. These methods try to convert a POMDP (...) environment into an MDP environment, and thus they are sometimes very useful. However, their computation cost is very high especially in large state spaces. In contrast, memory-less approaches try to escape from the aliased states by outputting actions stochastically. However, these methods output actions stochastically even in unaliased states, and thus the learning efficiency is bad. If we desire to guarantee the rationality in POMDPs, it is efficient to output actions stochastically only in the aliased states and to output one action deterministically in the other unaliased states. Hence, to discriminate between aliased states and unaliased states, the utilization of χ² -goodness-of-fit test is proposed by Miyazaki et al. They point out that, in aliased states, the distributions of the state transitions by random search and a particular policy are different. This difference doesn't occur owing to non-deterministic actions. Hence, if the agent can collect enough samples to implement the test, the agent can distinguish between aliased states and unaliased states well. However, such a test needs a large amount of data, and it's a problem how the agent collects samples without worsening learning efficiency. If the agent uses random search in the course of learning, the learning efficiency worsens especially in unaliased states. Therefore, in this research, we propose a new method called Extended On-line Profit Sharing with Judgement (EOPSwJ) to detect important incomplete perception, which doesn't need large computation cost and numerous samples. We use two criterions for detecting important incomplete perceptions to attain a task. One is the rate of transitions to each state, and the other is the deterministic rate of actions. We confirm the availability of EOPSwJ using two simulations. (shrink)

Estrogen receptor α (ERα) is a ligand‐dependent transcription factor that regulates the expression of estrogen‐responsive genes. Approximately 70% of patients with breast cancer are ERα positive. Estrogen stimulates cancer cell proliferation and contributes to tumor progression. Endocrine therapies, which suppress the ERα signaling pathway, significantly improve the prognosis of patients with breast cancer. However, the development of de novo or acquired endocrine therapy resistance remains a barrier to breast cancer treatment. Therefore, understanding the regulatory mechanisms of ERα is essential to (...) overcome the resistance to treatment. This review focuses on the regulation of ERα expression, including copy number variation, epigenetic regulation, transcriptional regulation, and stability, as well as functions from the point of view post‐translational modifications. (shrink)

Cytoskeletal organization in embryonic skeletal muscle cells has been examined by transmission electron microscopy; the technique involves preparation using the platinum replication method of freezedried samples, with and without cryofracture. The cytoskeletons in developing muscle cells appear to play a role in preserving cell shape as well as in anchoring myofibrils to cell membrane.

The standing screens on the title is the oldest work extant of KANO Motonobu's work as folding screens of thick colored flowers and birds with golden background. This thesis designates that the scenery and the motif of the work are in correspondence with both descriptions of the scenery of Pure Land in several Buddhist scriptures and the design of actual gardens. Firstly, a peacock on the right hand screen is focused to indicate the bird connotes the elements of auspicious birds (...) in Buddhism, such as Mahamayuri and Kalavinka.Secondly, the elements of the scenery in the work, such as the four seasons at the same time ∼ the depiction of perpetuity ∼ and the existence of a pond, are identified with the description of Pure Land in Kwan-mu-liang-shou-ching and Ta-wuliang-shou-ching. These elements of the garden in the work are placed similarly to the Pure Land style gardens, which are illustrated in "Center and Surrounds of Kyoto" 's. In consideration of the above factors, the conclusion that, in the work, KANO Motonobu succeeded to portray the ideal garden by combining the scenery of Pure Land and that of actual gardens, is drawn. (shrink)

Familial amyloidotic polyneuropathy (FAP) is an inherited systemic amyloidosis, characterized by the extracellular deposition of fibrillar amyloid protein, i.e. a variant type of prealbumin, and by prominent peripheral nerve involvement. We recently established the basis of FAP, using a cloned human prealbumin cDNA, restriction endonuclease(s) and Southern blot procedures. This approach clearly revealed a direct link between mutation in the prealbumin gene and FAP; individuals with FAP are heterozygous for the prealbumin gene, carrying one normal and one mutant gene. Molecular (...) analysis of the prealbumin gene yielded pertinent data on the genetic basis for FAP. (shrink)