The star-nosed mole is aptly named. Its distinctive snout consists of 22 tendrils ringing a pair of nostrils and, from some angles, the entire setup resembles a misshapen star. The tendrils are fleshy and look a bit like fingers, and, like fingers, they have a certain dexterity. But why? Why does the mole have such a singular appendage as opposed to something more ordinary? What is the function or purpose of this bizarre structure? From the dedicated work of Ken Catania, (...) of Vanderbilt University, and colleagues, it appears that the appendage facilitates rapid handling of small prey items, making it advantageous for an organism whose diet consists of tiny invertebrates. We might therefore hazard that this feature arose evolutionarily because it conferred this benefit. But the matter is difficult to resolve, because current utility does not permit a straightforward inference of a reason for existence. -/- A correction has been published: BioScience, Volume 72, Issue 7, July 2022, Page 708. (shrink)

Although random mutation is central to models of evolutionary change, a lack of clarity remains regarding the conceptual possibilities for thinking about the nature and role of mutation in evolution. We distinguish several claims at the intersection of mutation, evolution, and directionality and then characterize a previously unrecognized category: complex conditioned mutation. Empirical evidence in support of this category suggests that the historically famous fluctuation test should be revisited, and new experiments should be undertaken with emerging experimental techniques to facilitate (...) detecting mutation rates within specific loci at an ultra‐high, individual base pair resolution. (shrink)

Given the pervasiveness of gene sharing in evolution and the extent of homology across the tree of life, why is everything not homologous with everything else? The continuity and overlapping genetic contributions to diverse traits across lineages seem to imply that no discrete determination of homology is possible. Although some argue that the widespread overlap in parts and processes should be acknowledged as “partial” homology, this threatens a broad base of presumed comparative morphological knowledge accepted by most biologists. Following a (...) long scientific tradition, we advocate a strategy of “theoretical articulation” that introduces further distinctions to existing concepts to produce increased contrastive resolution among the labels used to represent biological phenomena. We pursue this strategy by drawing on successful patterns of reasoning from serial homology at the level of gene sequences to generate an enriched characterization of serial homology as a hierarchical, phylogenetic concept. Specifically, we propose that the concept of serial homology should be applied primarily to repeated but developmentally individualized body parts, such as cell types, differentiated body segments, or epidermal appendages. For these characters, a phylogenetic history can be reconstructed, similar to families of paralogous genes, endowing the notion of serial homology with a hierarchical, phylogenetic interpretation. On this basis, we propose a five-fold theoretical classification that permits a more fine-grained mapping of diverse trait-types. This facilitates answering the question of why everything is not homologous with everything else, as well as how novelty is possible given that any new character possesses evolutionary precursors. We illustrate the fecundity of our account by reference to debates over insect wing serial homologs and vertebrate paired appendages. (shrink)

We introduce the notion of a lovely pair of models of a simple theory T, generalizing Poizat's “belles paires” of models of a stable theory and the third author's “generic pairs” of models of an SU-rank 1 theory. We characterize when a saturated model of the theory TP of lovely pairs is a lovely pair , finding an analog of the nonfinite cover property for simple theories. We show that, under these hypotheses, TP is also (...) simple, and we study forking and canonical bases in TP. We also prove that assuming only that T is low, the existentially universal models of the universal part of a natural expansion TP+ of TP, are lovely pairs, and “simple Robinson universal domains”. (shrink)

We study the theory of lovely pairs of geometric structures, in particular o-minimal structures. We use the pairs to isolate a class of geometric structures called weakly locally modular which generalizes the class of linear structures in the settings of SU-rank one theories and o-minimal theories. For o-minimal theories, we use the Peterzil–Starchenko trichotomy theorem to characterize for a sufficiently general point, the local geometry around it in terms of the thorn U-rank of its type inside a (...) lovely pair. (shrink)

We prove that for every simple theory $T$ (or even simple thick compact abstract theory) there is a (unique) compact abstract theory $T^fP$ whose saturated models are the lovely pairs of $T$. Independence-theoretic results that were proved in [Ben Yaacov, Pillay, Vassiliev - Lovely pairs of models] when $T^fP$ is a first order theory are proved for the general case: in particular $T^fP$ is simple and we characterise independence.

Given a lovely pair P ≺ M of models of a simple theory T, we study the structure whose universe is P and whose relations are the traces on P of definable (in ℒ with parameters from M) sets in M. We give a necessary and sufficient condition on T (which we call weak lowness) for this structure to have quantifier-elimination. We give an example of a non-weakly-low simple theory.

We prove that the definition of supersimplicity in metric structures from [Ben Yaacov, Uncountable dense categoricity in cats] is equivalent to an textit{a priori} stronger variant. This stronger variant is then used to prove that if $T$ is a supersimple Hausdorff cat then so is its theory of lovely pairs.

We prove that the definition of supersimplicity in metric structures from [7] is equivalent to an a priori stronger variant. This stronger variant is then used to prove that if T is a supersimple Hausdorff cat then so is its theory of lovely pairs.

Del Giudice proposes that short-term mating strategies are adaptive for attachment-avoidant men. We argue that this model (1) does not apply to the majority of avoidant men (fearful-avoidants); (2) is based on limited evidence that the remaining subset of avoidant men (dismissing-avoidants) engage in short-term mating strategies; and (3) disregards the importance of pair bonding even for dismissing-avoidants.

We provide a general theorem implying that for a (strongly) dependent theory T the theory of sufficiently well-behaved pairs of models of T is again (strongly) dependent. We apply the theorem to the case of lovely pairs of thorn-rank one theories as well as to a setting of dense pairs of first-order topological theories.

We study definable groups in dense/codense expansions of geometric theories with a new predicate P such as lovely pairs and expansions of fields by groups with the Mann property. We show that in such expansions, large definable subgroups of groups definable in the original language \ are also \-definable, and definably amenable \-definable groups remain amenable in the expansion. We also show that if the underlying geometric theory is NIP, and G is a group definable in a model (...) of T, then the connected component \ of G in the expansion agrees with the connected component \ in the original language. We prove similar preservation results for \^n\), the P-part of G in a lovely pair, and for subgroups of G in pairs where R is a real closed field and G is a subgroup of \ or the unit circle \\) with the Mann property. (shrink)

Generalising work of Berenstein, Dolich and Onshuus (Preprint 145 on MODNET Preprint server, 2008) and Günaydın and Hieronymi (Preprint 146 on MODNET Preprint server, 2010), we give sufficient conditions for a theory TP to inherit N I P from T, where TP is an expansion of the theory T by a unary predicate P. We apply our result to theories, studied by Belegradek and Zilber (J. Lond. Math. Soc. 78:563–579, 2008), of the real field with a subgroup of the unit (...) circle. (shrink)

In a pair of articles published in Faith and Philosophy, C. Stephen Evans argues that Kierkegaard’s pseudonym, Johannes Climacus, understands religious experience as the transforming power of an encounter with the love of God. However, in a book published under his own name, Kierkegaard gives a quite different picture of Christian experience. For Self-Examination makes clear that the reception of God’s love is a rebirth that can occur in the believer only insofar as he or she has died to the (...) world - to all possessions, even to the possession of God’s love. According to Kierkegaard, this “dying to” is the truly transforming experience that characterizes Christian spirituality, and that provides the condition for a life infused with faith, hope, and love. (shrink)

In a pair of articles published in Faith and Philosophy, C. Stephen Evans argues that Kierkegaard’s pseudonym, Johannes Climacus, understands religious experience as the transforming power of an encounter with the love of God. However, in a book published under his own name, Kierkegaard gives a quite different picture of Christian experience. For Self-Examination makes clear that the reception of God’s love is a rebirth that can occur in the believer only insofar as he or she has died to the (...) world - to all possessions, even to the possession of God’s love. According to Kierkegaard, this “dying to” is the truly transforming experience that characterizes Christian spirituality, and that provides the condition for a life infused with faith, hope, and love. (shrink)

The matched pair ‘love’ and ‘attention’ is familiar to most of us from the essays in Iris Murdoch's The Sovereignty of Good. Although she tells us in that book that there is, in her view, no God in the traditional sense of that term, she provides accounts of art, prayer and morality that are religious. ‘Morality’, she tells us, ‘has always been connected with religion and religion with mysticism’ . The connection here is love and attention: ‘Virtue is au fond (...) the same in the artist as in the good man in that it is a selfless attention to nature’ . Art and morals are two aspects of the same struggle; both involve attending, a task of attention which goes on all the time, efforts of imagination which are important cumulatively . ‘Prayer’, she says, ‘is properly not petition, but simply an attention to God which is a form of love’. (shrink)

Spurred by Judith Butler’s seminal work, Pamela Anderson finds herself challenged to rethink her ontological assumptions, away from the traditional conceptions of the self. This essay is an attempt to face this challenge upfront, and come to terms with the kind of vulnerability that Anderson wants to vindicate. I start with distinguishing different contrastive but interlocking pairs of concepts of vulnerability: the ontological and the ethical, the pathogenic and the self-enhancing, the inherent and the circumstantial. I then argue for (...) the relevance of ontological vulnerability and suggest that it reveals the apparent normative structure of human agency and indicates the root of mutual accountability. In this perspective, human vulnerability to love and love’s own vulnerability can be appreciated and reassessed as a distinctive drive to cooperative interactions and shared agency, which allows finite and interdependent agents to deal and cope with contingency and temporality, by relying on mutually accountable relations. Focusing on the dynamic reciprocal permeability which is distinctive of love, I concur with Anderson that emotional vulnerability is not the source of burdens and constraints but a precious capacity that enables relations of mutual accountability, shapes human identity, expands individual agency, and shapes integrity in interactive and historical ways. (shrink)

This paper reviews the evolutionary history and biology of love and marriage. It examines the current and imminent possibilities of biological manipulation of lust, attraction and attachment, so called neuroenhancement of love. We examine the arguments for and against these biological interventions to influence love. We argue that biological interventions offer an important adjunct to psychosocial interventions, especially given the biological limitations inherent in human love.

In lieu of an abstract, here is a brief excerpt of the content:Looking at Love an Ethics of VisionMieke Bal (bio)Kaja Silverman. The Threshold Of The Visible World. New York: Routledge, 1996.“The eye can confer the active gift of love upon bodies which have long been accustomed to neglect and disdain,” writes Kaja Silverman in her most recent book, The Threshold of the Visible World. The sentence neatly summarizes her project. “The active gift of love” is the central concept of (...) this book and indicative of the utopian dimension of the theory of love she develops.With Lacan as her primary interlocutor, she sets out to answer a question of one of her students: “does psychoanalysis have a theory of love?” Strange as it might seem, psychoanalysis, so often associated with an excessive interest in sexuality, has not seemed to believe in love. Within the rigorous framework of a discipline that has no use for love and theorizes a bleak view of human nature, Silverman sets out to think through the questions that every parent is at a loss, yet needs, to address: what is love, how can choices in love be culturally encouraged, reoriented, or discouraged? Lacan’s texts on the imaginary order and the visual field, and the imaginary’s stubborn presence within the symbolic order, remain a key resource for those who, like Silverman, wish to understand and analyze, critique and refocus contemporary culture with an eye open to contradictions and complexities. 1The ground for love, the ability to love, is idealization, Silverman claims. Without idealization life would be unbearable, but idealizing is influenced by cultural norms and values that we internalize from early childhood on. Silverman’s project—”to articulate the psychic and aesthetic conditions under which we might be carried away from both ideality and the self, and situated in an identificatory relation to [culturally] despised bodies” [2]—is an attempt to put pressure on two elements of this interaction, “idealization” and “self,” but as she does so she acknowledges the force of the transhistorical, heavy, thick structure of the psyche that is hard, if not impossible, to change.This project, the development of an “ethics of vision,” forms a key part within the larger framework of Silverman’s work. In her first book, The Subject of Semiotics, she argues for and explains the semiotic status of psychoanalysis and the indispensable contribution of psychoanalysis to semiotics. The book remains a valuable handbook for an understanding of the importance of such divergent theorists as De Saussure and Benveniste, Kristeva and Peirce, Freud and Lacan, and the theorists of suture for a coherent and comprehensive theory of culture. One example that will speak to many a cultural analyst is the way Silverman disentangles, and then connects again, the often conflated conceptual pairs of metaphor and metonymy, condensation and displacement, and paradigm and syntagma, showing that the first pair is situated on the level of interactions between the signifier and [End Page 59] the signified, the second on the level of the signified, and the third on the level of the structuration of the signifier. 2With this book, then, Silverman lays the foundation for a psychoanalytical semiotic that is nevertheless radically cultural in orientation: no conflation or confusion of psyche and culture, no flattening of the one through the other, but an integration that demonstrates convincingly that what happens within a psyche is irrevocably cultural and that every cultural expression entertains a relationship with one or more psyches. The structural similarities and interactions between the two then seem self-evident. But how these interactions work is explained in a manner that renders them analyzable.Silverman is in the habit of raising questions that remain unanswered, and devoting her next book to them. The Subject devoted much attention and analytical energy to filmic images, notably through suture theory, in which the technique of “shot-reverse shot” is central. This technique consists of successive images: first of a character looking at something, and then of what that character presumably sees. This would be the cinematic equivalent of what narratology calls transitions of focalization, likewise a technique used to “suture” image to diegetic character in order to stimulate identification. As in narratology, the question then arises: what exactly... (shrink)

Romantic love is a phenomenon of immense interest to the general public as well as to scholars in several disciplines. It is known to be present in almost all human societies and has been studied from a number of perspectives. In this integrative review, we bring together what is known about romantic love using Tinbergen’s “four questions” framework originating from evolutionary biology. Under the first question, related to mechanisms, we show that it is caused by social, psychological mate choice, genetic, (...) neural, and endocrine mechanisms. The mechanisms regulating psychopathology, cognitive biases, and animal models provide further insights into the mechanisms that regulate romantic love. Under the second question, related to development, we show that romantic love exists across the human lifespan in both sexes. We summarize what is known about its development and the internal and external factors that influence it. We consider cross-cultural perspectives and raise the issue of evolutionary mismatch. Under the third question, related to function, we discuss the fitness-relevant benefits and costs of romantic love with reference to mate choice, courtship, sex, and pair-bonding. We outline three possible selective pressures and contend that romantic love is a suite of adaptions and by-products. Under the fourth question, related to phylogeny, we summarize theories of romantic love’s evolutionary history and show that romantic love probably evolved in concert with pair-bonds in our recent ancestors. We describe the mammalian antecedents to romantic love and the contribution of genes and culture to the expression of modern romantic love. We advance four potential scenarios for the evolution of romantic love. We conclude by summarizing what Tinbergen’s four questions tell us, highlighting outstanding questions as avenues of potential future research, and suggesting a novel ethologically informed working definition to accommodate the multi-faceted understanding of romantic love advanced in this review. (shrink)

Neuropeptides vasopressin and oxytocin regulate a variety of behaviors ranging from maternal and pair bonding to aggression and fear. Their role in modulating fear responses has been widely recognized, but not yet well understood. Animal and human studies indicate the major role of the amygdala in controlling fear and anxiety. The amygdala is involved in detecting threat stimuli and linking them to defensive behaviors. This is accomplished by projections connecting the central nucleus of the amygdala (CeA) to the brain stem (...) and to hypothalamic structures, which organize fear responses. A recent study by Huber et al1 demonstrates that vasopressin and oxytocin modulate the excitatory inputs into the CeA in opposite manners. Therefore this finding elucidates the mechanisms through which these neuropeptides may control the expression of fear. BioEssays 27:869–873, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Literature 26.2 (2002) 415-431 [Access article in PDF] The Humanities at Home with Themselves Mark Bauerlein The Crafty Reader, by Robert Scholes; 272 pp. New Haven: Yale University Press, 2002, $24.95. WHEN I STARTED GRADUATE SCHOOL in English in the early Eight ies, a typical thing happened. Those few students with a background in philosophy drifted together, shared influences, and developed a hierarchy of critical works. A (...) few pushed analytic philosophy and pragmatism, but overall Continental theory took first place, especially Derrida. "Structure, Sign, and Play" and "White Mythology," de Man's "Rhetoric of Temporality," Shoshana Felman's "Turning the Screw of Interpretation," and other weighty essays had the status of cutting-edge wisdom, and the hostility deconstruction drew from traditionalists and Marxists in the department only sharpened our commitment. Having no other professional standing, we savored the stigma, the roguishness. It complemented our poverty, and eased our transition from hot-shot undergraduates to first-year, prequalifying Ph.D aspirants. In the evenings, after instructing freshmen in comma splices, we gathered to trade Nietszchean epigrams and mock professors who looked befuddled at the mention of a priori and aporia.Other students found us insufferable, and doubtless we were, but not in a partisan way. We panned each other just as hard as we did the uninformed. This was UCLA, not Yale or Johns Hopkins, and personalities mattered less than arguments. If in discussion I backed a point with [End Page 415] "As Derrida says...," someone always answered, "So what?" We frowned on arguments from authority. Popularizations such as Jonathan Culler's On Deconstruction earned our scorn. They were one step up from Cliff's Notes, packed with servile observations like "Jean Baudrillard wants to take us further, into a world where everything is so textualized that there is no space left for the real." We preferred to understand deconstruction through laborious readings of Being and Time and Beyond Good and Evil, not in watery effusions about textuality or the mechanical pairing of binary oppositions. The latter we placed among the scribes, those well-intentioned professionals canny enough to recognize the broad import of deconstruction, but not acute enough to discern the real meaning of différance or the radical disclosure of the ontic-ontological difference. The genius of philosophy, we thought, lay in plumbing the fundamental habits of cognition, like Hegel breaking down sense certainty and Heidegger questioning the determination of Being as substance. Exegesis of other texts was a lesser activity, though we acknowledged exceptions such as Starobinski's book on Rousseau and Kojève's lectures on The Phenomenology of Spirit.Lower in our rankings were the quasi-Leftist attacks just emerging, such as Frank Lentricchia's Criticism and Social Change, which cast theorists as mandarin functionaries treating interpretation as an apolitical game. They filled the page with spiteful terms like "the mask of pure reason" and righteous declarations like "it is wrong to claim that you are above politics," spurning argument for the rhetoric of the reformer. We diagnosed them as puny reactions to the Reagan Revolution, carried out on the irrelevant ground of literary theory. Philosophically, Lentricchia was a hack, and we rejected the imputation that theory nullified activism and justified the status quo. Not that we thought theory bred activism. We just considered them separate activities, and saw no determinate connection between hermeneutical stance and party affiliation. However, we accepted the elitist charge. How could ambitious academics avoid elitism? It wasn't hard for graduate students struggling on $900 a month to see that populist attitudes didn't suit the tenured Ivy Leaguer. Professors were paid by exclusive institutions to teach poetry, to write letters for the best and brightest, to run recondite journals and jet to prestigious symposia. We wanted to join them, but not with phony expressions of social injustice that targeted theory as the problem.Allied with the political attacks on theory, and esteemed even lower, were critiques of the humanities as a bastion of high culture. Polemics [End Page 416] such as Andrew Ross's No Respect: Intellectuals and Popular Culture treated... (shrink)

In this extraordinary tribute to the importance of the ordinary places in our lives, fifty-two Minnesotans write about the special, sometimes secret, places that give their lives meaning. For some it is their home or cabin or lake. For others, it's a family farm or neighbourhood park, a backyard garden or north woods trail: all places where we find a personal and spiritual connection to the land. VOICES FOR THE LAND explores this complex relationship by linking these personal essays with (...) striking images captured by award-winning photographer Brian Peterson. This marriage of words, images, and landscape provides a powerful reminder of our deep and abiding connection to the land. The writers share the experience of these favourite places through their senses, from the aching tingle of a cold winter night and the sound of ice 'singing' to the buzz of mosquitoes and the acrid smell of burning peat. The Voices for the Land project, organised by the non-profit group 1000 Friends of Minnesota, encouraged Minnesotans to write about the land they love and to fight for its preservation. The Minneapolis Star Tribune published a selection of these essays, paired with Brian Peterson's photos, in an award-winning series. VOICES FOR THE LAND brings these essays and photos together in book form for the first time. (shrink)

Might paranoia bear some promise, not only danger, for democratic theory and politics? To suggest that we should treat paranoia with anything but disdain today, in the age of Q anon and other white-supremacist lies, seems dangerous. But three decades ago, feminist theorist Naomi Schor took the risk and defended female paranoia, arguing that paranoia is an appropriate affect for feminist theory and critique. This essay follows Schor’s invitation to risk proximity to paranoia. I argue that the political importance of (...) Schor’s essay lies in one particular attribute of female paranoia that she celebrates: its love of detail. To explore the promise and limitations of the paranoid love of detail I pair Schor with two 20th-century theorists – Hannah Arendt and Simone de Beauvoir. Each studies a paranoid woman who clings to details: Arendt’s Rahel Varnhagen counts the number of teacups that she serves in her German salon. Beauvoir’s housewife collects tufts of dust. With Schor, Arendt and Beauvoir, the article argues that love of detail is a critical component not only of paranoid indictments of the world, but also of any project that desires to repair the world in the wake of paranoia. (shrink)

The myth of true, lifelong love promoted low divorce rates among farmers who depended on each other for survival. In the urban ecology after industrialization, it became increas­ingly clear that long-term monogamy goes against human nature. In the Scandinavian Modern Breakthrough, a late-1800s literary movement, Henrik Ibsen, August Strindberg, and others clashed in a battle over modern mating morality. Each interpreted Darwin to fit their own agenda, suggesting naturalistic understandings of “free love” and “true mar­riage,” some of which were laughable (...) while others landed authors in prison. Evolutionary theory from our present era suggests that human mate choice is guided by three brain systems: erotic lust, romantic love, and feelings of deep attachment; our species thus evolved for serial pair-bonding with extra-pair copulation. Using these and other evolutionary insights, this article evaluates narratives from the Modern Breakthrough, which laid the foundation for today’s gender-equal and sexually liberal Nordic societies. (shrink)

I often imagine how good it would be to have a pair of those infrared binoculars -- the ones always used by the hero in movies to see what's ordinarily hidden by darkness. Similar is the alien's vision of warmth in _Predator_. In this film the commandos, led by Arnold Schwarzenegger, cannot escape the prying eyes that see the warmth of their bodies (no matter how much guerrilla is in their warfare).

Evolutionary developmental biology (or developmental evolution) is in the middle stages of its “development.” Its early ontogeny cannot be traced back to fertilization but pivotal developmental events included Gould’s (1977) treatment of heterochrony, Riedl’s (1978) analysis of “burden”, the Dahlem conference of 1981, a British Society of Developmental Biologists Symposium, as well as books that incorporated developmental genetics into older comparative themes. A major inductive process began with the discovery of widespread phylogenetic conservation in homeobox-containing genes. One interpretation of these (...) early developmental dynamics holds that an increasingly prominent problem agenda (e.g., how do novel structures and functions originate?), inherited from long-standing research programs in comparative embryology, morphology, and paleontology, was handed a powerful set of experimental tools from the lineage of experimental embryology. This allowed for an experimental probing of development and its evolution in an unprecedented fashion. Although the relationship between evolution and development has exhibited a protracted and complex history, we are still in the process of comprehending these early stages of “modern” EvoDevo’s ontogeny. (shrink)

It is a common complaint that antireductionist arguments are primarily negative. Here I describe an alternative nonreductionist epistemology based on considerations taken from multidisciplinary research in biology. The core of this framework consists in seeing investigation as coordinated around sets of problems (problem agendas) that have associated criteria of explanatory adequacy. These ideas are developed in a case study, the explanation of evolutionary innovations and novelties, which demonstrates the applicability and fruitfulness of this nonreductionist epistemological perspective. This account also bears (...) on questions of conceptual change and theory structure in philosophy of science. †To contact the author, please write to: Department of Philosophy, University of Minnesota, 831 Heller Hall, 271 19th Ave. S., Minneapolis, MN 55455; e‐mail: [email protected]. (shrink)

“Functional homology” appears regularly in different areas of biological research and yet it is apparently a contradiction in terms—homology concerns identity of structure regardless of form and function. I argue that despite this conceptual tension there is a legitimate conception of ‘homology of function’, which can be recovered by utilizing a distinction from pre-Darwinian physiology (use versus activity) to identify an appropriate meaning of ‘function’. This account is directly applicable to molecular developmental biology and shares a connection to the theme (...) of hierarchy in homology. I situate ‘homology of function’ within existing definitions and criteria for structural assessments of homology, and introduce a criterion of ‘organization’ for judging function homologues, which focuses on hierarchically interconnected interdependencies (similar to relative position and connection for skeletal elements in structural homology). This analysis of biological concepts has at least three broad philosophical consequences: (1) it provides the grounds for the study of behavior and psychological categories as homologues; (2) it demonstrates that philosophers who take selected effect function as primary effectively ignore large portions of comparative, structural, and experimental research, thereby misconstruing biological reasoning and knowledge; and, (3) it underwrites causal generalizations, which illuminates inferences made from model organisms in experimental biology. (shrink)

One foundational question in contemporarybiology is how to `rejoin evolution anddevelopment. The emerging research program(evolutionary developmental biology or`evo-devo) requires a meshing of disciplines,concepts, and explanations that have beendeveloped largely in independence over the pastcentury. In the attempt to comprehend thepresent separation between evolution anddevelopment much attention has been paid to thesplit between genetics and embryology in theearly part of the 20th century with itscodification in the exclusion of embryologyfrom the Modern Synthesis. This encourages acharacterization of evolutionary developmentalbiology as the marriage (...) of evolutionary theoryand embryology via developmental genetics. Butthere remains a largely untold story about thesignificance of morphology and comparativeanatomy (also minimized in the ModernSynthesis). Functional and evolutionarymorphology are critical for understanding thedevelopment of a concept central toevolutionary developmental biology,evolutionary innovation. Highlighting thediscipline of morphology and the concepts ofinnovation and novelty provides an alternativeway of conceptualizing the `evo and the `devoto be synthesized. (shrink)

The goal of this paper is to encourage a reconfiguration of the discussion about typology in biology away from the metaphysics of essentialism and toward the epistemology of classifying natural phenomena for the purposes of empirical inquiry. First, I briefly review arguments concerning ‘typological thinking’, essentialism, species, and natural kinds, highlighting their predominantly metaphysical nature. Second, I use a distinction between the aims, strategies, and tactics of science to suggest how a shift from metaphysics to epistemology might be accomplished. Typological (...) thinking can be understood as a scientific tactic that involves representing natural phenomena using idealizations and approximations, which facilitates explanation, investigation, and theorizing via abstraction and generalization. Third, a variety of typologies from different areas of biology are introduced to emphasize the diversity of this representational reasoning. One particular example is used to examine how there can be epistemological conflict between typology and evolutionary analysis. This demonstrates that alternative strategies of typological thinking arise due to the divergent explanatory goals of researchers working in different disciplines with disparate methodologies. I conclude with several research questions that emerge from an epistemological reconfiguration of typology. (shrink)

This volume explores questions about conceptual change from both scientific and philosophical viewpoints by analyzing the recent history of evolutionary developmental biology. It features revised papers that originated from the workshop "Conceptual Change in Biological Science: Evolutionary Developmental Biology, 1981-2011" held at the Max Planck Institute for the History of Science in Berlin in July 2010. The Preface has been written by Ron Amundson. In these papers, philosophers and biologists compare and contrast key concepts in evolutionary developmental biology and their (...) development since the original, seminal Dahlem conference on evolution and development held in Berlin in 1981. Many of the original scientific participants from the 1981 conference are also contributors to this new volume and, in conjunction with other expert biologists and philosophers specializing on these topics, provide an authoritative, comprehensive view on the subject. Taken together, the papers supply novel perspectives on how and why the conceptual landscape has shifted and stabilized in particular ways, yielding insights into the dynamic epistemic changes that have occurred over the past three decades. This volume will appeal to philosophers of biology studying conceptual change, evolutionary developmental biologists focused on comprehending the genesis of their field and evaluating its future directions, and historians of biology examining this period when the intersection of evolution and development rose again to prominence in biological science. (shrink)

Although no one unified anarchist theory exists, educational approaches can be taken to support the full liberation of the self and the construction of an interconnected community that strives to rid itself of eco-sociocultural oppressions. An anarchist pedagogical approach could be one that is rooted in a love/rage unit of analysis occurring along a spectrum of various types of actions and contributions within a community. Anarchism as a violent destruction of the state is a stereotypical view that has perhaps led (...) to its own early demise as a social movement. Anarchism that embraces adaptation through more inclusive forms of resistance, including a reconstruction for the K?12 classroom context, is one that stands a chance in evolving a society toward love, justice, and empowerment. This article explores those possibilities aiming for accessibility while still honoring core anarchist calls for strong, localized democratic participation and decision-making outside of permanent hierarchies. (shrink)

Many philosophers of biology have embraced a version of pluralism in response to the failure of theory reduction but overlook how concepts, methods, and explanatory resources are in fact coordinated, such as in interdisciplinary research where the aim is to integrate different strands into an articulated whole. This is observable for the origin of evolutionary novelty—a complex problem that requires a synthesis of intellectual resources from different fields to arrive at robust answers to multiple allied questions. It is an apt (...) locus for exploring new dimensions of explanatory integration because it necessitates coordination among historical and experimental disciplines . These coordination issues are widespread for the origin of novel morphologies observed in the Cambrian Explosion. Despite an explicit commitment to an integrated, interdisciplinary explanation, some potential disciplinary contributors are excluded. Notable among these exclusions is the physics of ontogeny. We argue that two different dimensions of integration—data and standards—have been insufficiently distinguished. This distinction accounts for why physics-based explanatory contributions to the origin of novelty have been resisted: they do not integrate certain types of data and differ in how they conceptualize the standard of uniformitarianism in historical, causal explanations. Our analysis of these different dimensions of integration contributes to the development of more adequate and integrated explanatory frameworks. (shrink)

Causal relations among components and activities are intentionally misrepresented in mechanistic explanations found routinely across the life sciences. Since several mechanists explicitly advocate accurately representing factors that make a difference to the outcome, these idealizations conflict with the stated rationale for mechanistic explanation. We argue that these idealizations signal an overlooked feature of reasoning in molecular and cell biology—mechanistic explanations do not occur in isolation—and suggest that explanatory practices within the mechanistic tradition share commonalities with model-based approaches prevalent in population (...) biology. (shrink)

Although natural philosophers have long been interested in individuality, it has been of interest to contemporary philosophers of biology because of its role in different aspects of evolutionary biology. These debates include whether species are individuals or classes, what counts as a unit of selection, and how transitions in individuality occur evolutionarily. Philosophical analyses are often conducted in terms of metaphysics (“what is an individual?”), rather than epistemology (“how can and do researchers conceptualize individuals so as to address some of (...) their scientific goals?”). We review several philosophical distinctions in order to shift attention from metaphysics to epistemology. Many controversies involve epistemological differences rather than metaphysical disagreement. This implies that a pluralist stance about individuality in biology is warranted and has metaphysical consequences because the pluralism emerges from the diversity of scientific interests that investigate the complexity of living phenomena. (shrink)

Although the role of morphology in evolutionary theory remains a subject of debate, assessing the contributions of morphological investigation to evolutionary developmental biology (Evo-devo) is a more circumscribed issue of direct relevance to ongoing research. Historical studies of morphologically oriented researchers and the formation of the Modern Synthesis in the Anglo-American context identify a recurring theme: the synthetic theory of evolution did not capture multiple levels of biological organization. When this feature is incorporated into a philosophical framework for explaining the (...) origin of evolutionary innovations and novelties (a core domain of inquiry in Evo-devo) two specific roles for morphology can be described: (1) the conceptualization and operational identification of the targets of explanation; and (2) the elucidation of causal interactions at higher levels of organization during ontogeny and through evolutionary time. These roles are critical components of any adequate explanation of innovation and novelty though not exhaustive of the parts played by morphology in evolutionary investigation. They also invite reflection on what counts as an evolutionary cause in contemporary evolutionary biology. (shrink)

Many biologists and philosophers have worried that importing models of reasoning from the physical sciences obscures our understanding of reasoning in the life sciences. In this paper we discuss one example that partially validates this concern: part-whole reductive explanations. Biology and physics tend to incorporate different models of temporality in part-whole reductive explanations. This results from differential emphases on compositional and causal facets of reductive explanations, which have not been distinguished reliably in prior philosophical analyses. Keeping these two facets distinct (...) facilitates the identifi cation of two further aspects of reductive explanation: intrinsicality and fundamentality. Our account provides resources for discriminating between different types of reductive explanation and suggests a new approach to comprehending similarities and differences in the explanatory reasoning found in biology and physics. (shrink)

The Routledge Handbook of Mechanisms and Mechanical Philosophy is an outstanding reference source to the key topics, problems, and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors, the Handbook is divided into four Parts: Historical perspectives on mechanisms The nature of mechanisms Mechanisms and the philosophy of science Disciplinary perspectives on mechanisms. Within these Parts central topics and problems are examined, including the rise of mechanical (...) philosophy in the seventeenth century; what mechanisms are made of and how they are organized; mechanisms and laws and regularities; how mechanisms are discovered and explained; dynamical systems theory; and disciplinary perspectives from physics, chemistry, biology, biomedicine, ecology, neuroscience, and the social sciences. Essential reading for students and researchers in philosophy of science, the Handbook will also be of interest to those in related fields, such as metaphysics, philosophy of psychology, and history of science. (shrink)

Every scientist chooses a preferred level of analysis and this choice shapes the research program, even determining what counts as evidence. This contribution revisits Marr's three levels of analysis and evaluates the prospect of making progress at each individual level. After reviewing limitations of theorizing within a level, two strategies for integration across levels are considered. One is top–down in that it attempts to build a bridge from the computational to algorithmic level. Limitations of this approach include insufficient theoretical constraint (...) at the computation level to provide a foundation for integration, and that people are suboptimal for reasons other than capacity limitations. Instead, an inside-out approach is forwarded in which all three levels of analysis are integrated via the algorithmic level. This approach maximally leverages mutual data constraints at all levels. For example, algorithmic models can be used to interpret brain imaging data, and brain imaging data can be used to select among competing models. Examples of this approach to integration are provided. This merging of levels raises questions about the relevance of Marr's tripartite view. (shrink)

Using the context of controversies surrounding evolutionary developmental biology (EvoDevo) and the possibility of an Extended Evolutionary Synthesis, I provide an account of theory structure as idealized theory presentations that are always incomplete (partial) and shaped by their conceptual content (material rather than formal organization). These two characteristics are salient because the goals that organize and regulate scientific practice, including the activity of using a theory, are heterogeneous. This means that the same theory can be structured differently, in part because (...) theory presentations (as idealizations) intentionally depart from different features known to be present in a theory. Since there are diverse and potentially incompatible theory structures derived from heterogeneous goals found in scientific practices, a question arises about the absence of a unifying theory structure in the background. The notion of a “theory façade” offers a fruitful perspective on this potentially unsettling result. (shrink)

A Russian in Paris -- Russian contexts -- Madmen -- The possessed -- Godmen -- The Hegel lectures -- The last revolution -- Time no more -- The book of the dead -- The later writings -- Nobodies -- Roads or ruins? -- Why finality? -- The grand inquisitor.

In this paper I examine a dispositional property that has been receiving increased attention in biology, evolvability. First, I identify three compatible but distinct investigative approaches, distinguish two interpretations of evolvability, and treat the difference between dispositions of individuals versus populations. Second, I explore the relevance of philosophical distinctions about dispositions for evolvability, isolating the assumption that dispositions are intrinsically located. I conclude that some instances of evolvability cannot be understood as purely intrinsic to populations and suggest alternative strategies for (...) resolving this difficulty. (shrink)

Evolutionary developmental biology (Evo-devo) is a vibrant area of contemporary life science that should be (and is) increasingly incorporated into teaching curricula. Although the inclusion of this content is important for biological pedagogy at multiple levels of instruction, there are also philosophical lessons that can be drawn from the scientific practices found in Evo-devo. One feature of particular significance is the interdisciplinary nature of Evo-devo investigations and their resulting explanations. Instead of a single disciplinary approach being the most explanatory or (...) fundamental, different methodologies from biological disciplines must be synthesized to generate empirically adequate explanations. Thus, Evo-devo points toward a non-reductionist epistemology in biology. I review three areas where these synthetic efforts become manifest as a result of Evo-devo’s practices (form versus function reasoning styles; problem-structured investigations; idealizations related to studying model organisms), and then sketch some possible applications to teaching biology. These philosophical considerations provide resources for life science educators to address (and challenge) key aspects of the National Science Education Standards and Benchmarks for Scientific Literacy. (shrink)

Model organisms are central to contemporary biology and studies of embryogenesis in particular. Biologists utilize only a small number of species to experimentally elucidate the phenomena and mechanisms of development. Critics have questioned whether these experimental models are good representatives of their targets because of the inherent biases involved in their selection (e.g., rapid development and short generation time). A standard response is that the manipulative molecular techniques available for experimental analysis mitigate, if not counterbalance, this concern. But the most (...) powerful investigative techniques and molecular methods are applicable to single-celled organisms (‘microbes’). Why not use unicellular rather than multicellular model organisms, which are the standard for developmental biology? To claim that microbes are not good representatives takes us back to the original criticism leveled against model organisms. Using empirical case studies of microbes modeling ontogeny, we break out of this circle of reasoning by showing: (a) that the criterion of representation is more complex than earlier discussions have emphasized; and, (b) that different aspects of manipulability are comparable in importance to representation when deciding if a model organism is a good model. These aspects of manipulability harbor the prospect of enhancing representation. The result is a better understanding of how developmental biologists conceptualize research using experimental models and suggestions for underappreciated avenues of inquiry using microbes. More generally, it demonstrates how the practical aspects of experimental biology must be scrutinized in order to understand the associated scientific reasoning. (shrink)