The question of the influence of genes on behavior raises difficult philosophical and social issues. In this paper I delineate what I call the Developmentalist Challenge (DC) to assertions of genetic influence on behavior, and then examine the DC through an indepth analysis of the behavioral genetics of the nematode, C. elegans, with some briefer references to work on Drosophila. I argue that eight "rules" relating genes and behavior through environmentally-influenced and tangled neural nets capture the results of developmental (...) and behavioral studies on the nematode. Some elements of the DC are found to be sound and others are criticized. The essay concludes by examining the relations of this study to Kitcher's antireductionist arguments and Bechtel and Richardson's decomposition and localization heuristics. Some implications for human behavioral genetics are also briefly considered. (shrink)

The argument of this book is that there is a form of Christian philosophy congruent with the contemporary philosophical climate. According to the author, a philosophy is Christian to the extent that it is elaborated within a Christian Weltanschauung, that is, insofar as its spirit and fundamental contents are guided by Christian revelation and bear the impress of Christian redemption. Christian philosophy is not a single system, but rather a tradition which approaches philosophical problems from a Christian perspective. Within this (...) tradition there can exist a considerable variety of philosophical opinion, since Christian revelation leaves many questions undecided. To show that such a Christian philosophy is possible today the author spends the major part of the book surveying a number of currents in recent philosophy. One purpose of this survey is to examine the resources and weaknesses of various philosophical methodologies. More importantly, the survey is used as the basis for arguing that existentialism, phenomenology, and analytic philosophy have recently developed in directions which suggest the possibility of formulating a new metaphysics which is at once contemporary and compatible with Christian philosophy as the author understands it. This new metaphysics is one which steers a middle ground between dogmatism and relativism. It is at once synoptic, in that it seeks a coherent understanding of the whole of reality by filling in the gaps in individual and collective experience; categorial, in that it forges categories which "picture the pervasive and formative characteristics of the world which are indicated by the large-scale structural aspects of experience and language rather than by particular observations or individual terms"; perspectival, in the sense that such a metaphysics elaborates a view of the world judged adapted to the philosopher's basic human commitments, to the empirical facts, and to formal laws of coherence and consistency, but in such a way that it remains open to changing attitudes and insights. Though its basic argument is not hard to grasp, this book is not easy to read. Partially this is due to a rather plodding style, but primarily it is the result of the structure of the book, which is such that the author discourses at a level of considerable generality on the doctrines of a great many different philosophers. He does this partially in order to illustrate his understanding of the dialogical character of philosophy. Nevertheless, the author's aims might well have been better served by a briefer, more sharply honed argument.--H. F. (shrink)

The argument of this book is that there is a form of Christian philosophy congruent with the contemporary philosophical climate. According to the author, a philosophy is Christian to the extent that it is elaborated within a Christian Weltanschauung, that is, insofar as its spirit and fundamental contents are guided by Christian revelation and bear the impress of Christian redemption. Christian philosophy is not a single system, but rather a tradition which approaches philosophical problems from a Christian perspective. Within this (...) tradition there can exist a considerable variety of philosophical opinion, since Christian revelation leaves many questions undecided. To show that such a Christian philosophy is possible today the author spends the major part of the book surveying a number of currents in recent philosophy. One purpose of this survey is to examine the resources and weaknesses of various philosophical methodologies. More importantly, the survey is used as the basis for arguing that existentialism, phenomenology, and analytic philosophy have recently developed in directions which suggest the possibility of formulating a new metaphysics which is at once contemporary and compatible with Christian philosophy as the author understands it. This new metaphysics is one which steers a middle ground between dogmatism and relativism. It is at once synoptic, in that it seeks a coherent understanding of the whole of reality by filling in the gaps in individual and collective experience; categorial, in that it forges categories which "picture the pervasive and formative characteristics of the world which are indicated by the large-scale structural aspects of experience and language rather than by particular observations or individual terms"; perspectival, in the sense that such a metaphysics elaborates a view of the world judged adapted to the philosopher's basic human commitments, to the empirical facts, and to formal laws of coherence and consistency, but in such a way that it remains open to changing attitudes and insights. Though its basic argument is not hard to grasp, this book is not easy to read. Partially this is due to a rather plodding style, but primarily it is the result of the structure of the book, which is such that the author discourses at a level of considerable generality on the doctrines of a great many different philosophers. He does this partially in order to illustrate his understanding of the dialogical character of philosophy. Nevertheless, the author's aims might well have been better served by a briefer, more sharply honed argument.--H. F. (shrink)

PurposeEven low intensity exercise bouts of at least 15 min can improve feelings of energy and reduce systolic blood pressure. However, little is known about the psychological outcomes of briefer exercise bouts, particularly for modes of exercise that are more intense than level walking, and readily available to many working adults. This study assessed the effects of a 4-min bout of stair walking on FOE and feelings of fatigue.MethodsThirty-six young adult participants were randomized to either stair walking or seated (...) control groups. All participants walked on level-ground from a laboratory to a nearby stairwell and were seated for 4 min before beginning their experimental condition. Stair-walking participants walked up and down one flight of 16 stairs at their own pace for 4 min, while control participants remained seated during that time. Participants walked back to the laboratory for post-condition assessments. Measures of blood pressure, heart rate, rated perceived exertion, and the intensity of feelings of mental energy, mental fatigue, physical energy, and physical fatigue were assessed pre-and post-condition. Separate one-way ANOVAs were conducted on change scores for all variables.ResultsThe stair climbing group experienced significant increases in heart rate [F = 13.167, p < 0.001] and RPE [F = 93.844, p < 0.001] that were not observed in the seated control group. Four minutes of self-paced stair climbing resulted in small changes and non-significant differences within and between groups in blood pressure as well as FOE and FOF.ConclusionAlthough a 4-min self-paced exercise bout can convey short-term physiological health benefits, a 4-min bout of self-paced indoor stair walking in a stairwell was insufficient to lower blood pressure or change subjective FOE and fatigue in a sample that exhibited better than typical FOE and FOF at the pre-test. (shrink)

This article focusses on the generality of the entities involved in a geometric proof of the kind found in ancient Greek treatises: it shows that the standard modern translation of Greek mathematical propositions falsifies crucial syntactical elements, and employs an incorrect conception of the denotative letters in a Greek geometric proof; epigraphic evidence is adduced to show that these denotative letters are ‘letter-labels’. On this basis, the article explores the consequences of seeing that a Greek mathematical proposition is fully general, (...) and the ontological commitments underlying the stylistic practice. (shrink)

In a lengthy article E. Scerri and J. Worrall put forward the case for a novel ‘accommodationist’ version of the events surrounding the development of Mendeleef's Periodic Table 1869–1899. However these authors lay undue stress on the fact that President of the Royal Society of London Spottiswoode made absolutely no mention of Mendeleef's famous predictions in the Davy Medal eulogy in 1883 and undue stress on the fact that Cleve's classic 1879 Scandium paper contained an acknowledgement of Mendeleef's prior prediction (...) of eka-boron.They also fail to analyse in any detail the so-called ‘rare earth problem’ which, in the opinion of this author, causes problems for their account but not for a predictivist account. (shrink)

My discussion addresses the differences between analytic and continental philosophy concerning the use of logic and exact reasoning in philosophical practice. These differences are mainly examined in the light of the controversial dominance of Hegel's concept of logic (and theory of concept) in twentieth-century continental philosophy. The inquiry is developed in two parts. In the first (Sections 1-2), I indicate some aspects of the analytic-continental divide, pointing to the role that the topic 'logic and philosophy' plays in it. In the (...) second part (Sections 3-6), I give a short account of the views of logic which are typical of the three main trends of continental philosophy (see Table 1). I also suggest how, with the aid of some typical analytical devices, some continental 'anti-logical' attitudes may be corrected, on their own terms. (shrink)

The globalization in business and tourism becomes crucial more and more for the economical sustainability of local communities. In the presence of an epidemic outbreak, there must be such a decision on the policy by the host community as whether to accept visitors or not, the number of acceptable visitors, or the condition for acceptable visitors. Making use of an SIRI type of mathematical model, we consider the influence of visitors on the spread of a reinfectious disease in a community, (...) especially assuming that a certain proportion of accepted visitors are immune. The reinfectivity of disease here means that the immunity gained by either vaccination or recovery is imperfect. With the mathematical results obtained by our analysis on the model for such an epidemic dynamics of resident and visitor populations, we find that the acceptance of visitors could have a significant influence on the disease’s endemicity in the community, either suppressive or supportive. (shrink)

In a paper entitled "Revolution in Permanence", published in the collection "Karl Popper: Philosophy and Problems", John Worrall severely criticised several aspects of Karl Popper's work before commenting that "I have no doubt that, given sufficient motivation, a case could be constructed on the basis of such remarks that Popper had a more sophisticated version of theory production......". Part of Worrall's criticism is directed at a "strawpopper": in his "Darwinian Model" emphasising the similarities and differences between genetic mutation, variation in (...) animal behaviour and the gestation of scientific theories, Popper never stated that tentative scientific conjectures "while more or less random, are not completely blind." He was referring to variation in animal species behaviour, and about tentative scientific conjectures he said nothing, although common sense would indicate that presumably he regarded them as being less blind and less random. In Popper, giving a summary of his "Darwinian Model", he repaired this omission about tentative scientific conjectures by inserting the sentence "On a level of World 3 theory formation they are of the character of planned gropings into the unknown." Recent developments in the field of genetics, Lewis, Korn ) indicate that Popper's intuitions were along the modern lines while Worrall's intuitions are old fashioned. Therefore Popper's "Darwinian Model" remains both viable and fruitful. (shrink)

Background A morally sound framework for benefit-sharing is crucial to minimize research exploitation for research conducted in developing countries. However, in practice, it remains uncertain which stakeholders should be involved in the decision-making process regarding benefit-sharing and what the implications might be. Therefore the study aimed to empirically propose a framework for benefit-sharing negotiations in research by taking HIV vaccine trials as a case. Methods The study was conducted in Tanzania using a case study design and qualitative approaches. Data were (...) collected using in-depth interviews (IDI) and focus group discussions (FGD). A total of 37 study participants were selected purposively comprising institutional review board (IRB) members, researchers, community advisory board (CAB) members, a policymaker, and HIV/AIDS advocates. Deductive and inductive thematic analysis approaches were deployed to analyze collected data with the aid of MAXQDA version 20.4.0 software. Results The findings indicate a triangular relationship between the research community, researched community and intermediaries. However, the relationship ought to take into consideration the timing of negotiations, the level of understanding between parties and the phase of the clinical trial. The proposed framework operationalize partnership interactions in community-based participatory research. Conclusion In the context of this study, the suggested framework incorporates the research community, the community being researched, and intermediary parties. The framework would guarantee well-informed and inclusive decision-making regarding benefit-sharing in HIV vaccine trials and other health-related research conducted in resource-limited settings. (shrink)

The paper shows that, contrary to what has been held since the sixteenth-century mathematician Christoph Clavius, there is no application of consequentia mirabilis (CM) in Greek mathematical works. This is shown by means of a detailed discussion of the logical structure of the proofs where CM is allegedly employed. The point is further enlarged to a critical assessment of the unsound methodology applied by many interpreters in seeking for specific logical rules at work in ancient mathematical texts.

In discussing questions of free will, Soviet philosophers fail to distinguish conditions from causes. This makes them unable to understand the very opponents they like to criticize.

This paper explains how to use a new software tool for argument diagramming available free on the Internet, showing especially how it can be used in the classroom to enhance critical thinking in philosophy. The user loads a text file containing an argument into a box on the computer interface, and then creates an argument diagram by dragging lines from one node to another. A key feature is the support for argumentation schemes, common patterns of defeasible reasoning historically know as (...) topics . Several examples are presented, as well as the results of an experiment in using the system with students in a university classroom. (shrink)

The defining principle of evolutionary biology is that all species, extant and extinct, evolved from ancient prokaryotic cells. Their initial appearance and adaptive evolution are proposed to have been accompanied by a cellular sentience, by feelings, subjectivity or, in a word, 'consciousness'. Prokaryotic cells, such as archaea and bacteria, have natural unitary, valence-marked 'mental' representations. They process and evaluate sensory information in a context-dependent manner. They learn, establish memories, and communicate using biophysical fields acting on excitable membranes. Symbiotic eukaryotic cells, (...) which evolved much later, initiated a compound cellular subjectivity utilizing 'senomic' and 'ephaptic' principles that evolved into the varieties of consciousness seen in multicellular species. This Cellular Basis of Consciousness (CBC) model provides a novel framework within which to approach fundamental issues such as the origins of life and the emergence of mind. (shrink)

This study examines the outcomes of a four-year faculty learning community (FLC) that aimed to transform departmental ethics curriculum by supporting Earth Sciences faculty members as they ethically inquired into their teaching of ethics and refined existing courses in alignment with an Integrated Community-Engaged Learning and Ethical Reflection (ICELER) framework. We present ethnographic case studies that unpack processes through which three faculty members transformed undergraduate courses. We assembled case studies by triangulating interview data, course artifacts, and faculty reflections. We examine (...) how faculty (1) built awareness around teaching ethics, (2) took responsibility for and made judgments about teaching ethics, (3) experimented by designing and implementing ICELER-inspired courses, and (4) interrogated the outcomes of their ethics teaching, utilizing findings to enhance awareness and revise courses. The paper closes by introducing a model detailing how instructors inquire into ethics teaching and how model components might inspire future educational practice and research. (shrink)