Several DNA-damage detection and repair mechanisms have evolved to repair double-strand breaks induced by mutagens. Later in evolutionary history, DNA single- and double-strand cuts made possible immune diversity by V(D)J recombination and recombination at meiosis. Such cuts are induced endogenously and are highly regulated and controlled. In meiosis, DNA cuts are essential for the initiation of homologous recombination, and for the formation of joint molecule and crossovers. Many proteins that function during somatic DNA-damage detection and repair are also active during (...) homologous recombination. However, their meiotic functions may be altered from their somatic roles through localization, posttranslational modifications and/or interactions with meiosis-specific proteins. Presumably, somatic repair functions and meiotic recombination diverged during evolution, resulting in adaptations specific to sexual reproduction. BioEssays 27:795–808, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

Context is a notion that is commonly invoked in many linguistic studies, either with very general reference or, more specifically, in the light of one of a number of research approaches which assign distinct definitions to context, ranging from factors that can be recovered from a text, through social parameters serving as an index for the appropriation of discursive performance, to factors that bring texts into being and give them meaning. This exploratory and descriptive research problematises the notion of context (...) specifically on the grounds of English/Polish translation of corporate documentation processed in company registration proceedings, touching upon factors that are presumed to be discursively relevant in this communicative situation. The study is conducted from the perspective of the sociocultural approach and it adopts the parallel corpus methodology. The author discusses the concept of context on the ground of legal communication and secondarily presents a corpus-based description of the context categories that are idiosyncratic and potentially discursively relevant for the said communicative situation in the cross-linguistic perspective. The contextual variation is tested for its capacity to affect translation performance. The results reveal specific tendencies as regards the distribution patterns in the values corresponding to the investigated context categories. They point to some divergencies in translation output caused by the source text variantivity and they pave the way and directions for further research. Already at this stage the findings may have significant pedagogical value and they constitute a solid starting point for sociolinguistic research on discourse variantivity. (shrink)

In this study the author has focused on the impact of activeness and independence on the quality of life of seniors. Activeness is taken to mean the participation in regular everyday tasks. Functional independence is independence in everyday life. Quality of life in old age describes the level of satisfaction with life and indicators of successful ageing. The survey was conducted in October 2013 among four groups of seniors. Two variables determined the distribution of respondents: the level of activeness and (...) the functional independence of the seniors. The study involved 99 seniors from Sopot and Gdansk. Functional independence has a much greater impact on the quality of life of seniors than activeness in as much as independence is influenced by our state of health over which we may always have full control, whereas activeness to a large extent depends on ourselves. (shrink)

W swoim artykule przedstawiłam w skróconej formie problem społeczeństwa żydowskiego z przełomu lat 1933-1945 na terenie niemieckiego miasta Bayreuth, znanego w świecie jako miejsce corocznych festiwali wagnerowskich. Osoby zajmujące się historią, a w szczególności okresem II wojny światowej oraz ci, których pasjonuje z różnych powodów muzyka Ryszarda Wagnera, natkną się z pewnością na ślady historii miasta Bayreuth, będącego w tym czasie niemal świątynią kultu ideologii nazistowskiej. To tu właśnie tworzył wybitny, a zarazem uwielbiany przez Hitlera Niemiec: Ryszard Wagner. Fakt ten (...) pełnił dość istotną funkcję wspomagającą manipulację masami ludzkimi. Przypisywanie kompozytorowi oraz jego sztuce antysemityzmu okazało się czystym środkiem do celu, jakim było wyniszczenie narodu żydowskiego. Podsycanie nienawiści, propaganda, bojkoty ze strony nazistów, brutalna dyskryminacja społeczeństwa żydowskiego i niszczenie jego długowiecznego dobytku kulturowego przyniosło zamierzone efekty w postaci emigracji tej ludności na zachód, do Ameryki, Kanady oraz Izraela. Liczne deportacje i eksterminacja Żydów sprawiły, że niewielu wróciło po wojnie do Bayreuth. Szybko odrodziła się tu jednak kultura żydowska i znalazła po wojnie pełną akceptację społeczeństwa. Warto dodać, że Bayreuth cieszy się dziś ogólnym uznaniem w świecie muzyki. Co roku napływają tu rzesze zwolenników twórczości Ryszarda Wagnera z całego świata, podziwiając piękno jego muzyki oraz urocze krajobrazy Zielonego Wzgórza. (shrink)

The paper presents findings gathered in an exploratory, descriptive, corpus-based analysis of a parallel corpus composed of English corporate documents and their translations into Polish with regard to the frequency-related, binary strategy distribution pattern. In general, the author posits a distinctiveness of interlingual communication in the domain of law, as delineated by the institutional and disciplinary framework. The material extracted from the corpus and studied for its generic features points to the hermetic character of corporate written communication in English. The (...) thesis to be verified is whether there are any tendencies in the distribution of the translation strategies in the corpus texts. The research question was operationalised via coding the corpus extracts according to the binary strategy division scheme. Further, the data have been discussed in reference to the sociocultural background of the communicative situation covered under the analysis in order to account for the translators’ motivation. (shrink)

The paper explores the hypothesis that multinomials can act as authorship-based style distinguishing markers in legal communication. Specifically, the analysis focuses on identifying the quantitative distribution patterns of structural categories of multinomials as typical for two authorship categories and on their communicative function. The two authorship categories that are contrasted here are legal professionals/experts and lay people. The analysis is conducted in the corpus-based methodology with a custom-designed corpus of English, authentic texts found in the legal trade, in the domain (...) of company registration proceedings. The findings confirm that multinomials that are conventionally considered to be a feature of professional legal communication are also cognitively salient in lay communication. Further, the texts drafted by the two categories of authors are profiled by structurally distinct multinomials. Functionally, it has been demonstrated that the structurally distinct types of multinomials that are found quantitatively salient in the two authorship categories are used predominantly for specific stylistic and/or pragmatic functions. Stylistically, multinomials contribute to conventional and ritual patterns which are used to meet the formality standards that have evolved in specific legal professions where authority is of particular importance. Pragmatic factors which account for quantitative salience of specific, structurally profiled categories of multinomials involve mainly reduplication of multinomials that embody norm-related concepts, which is required on the ground of intertextuality and ensures the materialisation of legal effect. (shrink)

The paper aims at describing the findings and conclusions formulated in the analysis of the authorship factor in legal discourse. It is hypothesised that verbal structures show systemically varied distribution across legal discourse and the relevant distinctions run through the authorship categories. When it comes to the aim of the research it draws on the tradition of sociolinguistic methodology targeting issues related to language variation which follows the basic assumptions of functional grammar. From the point of view of the material (...) covered by the analysis it contributes to the research on legal discourse and specifically on its specialised domain referred to as corporate, company or business discourse. It provides additional empirical data pointing to the non-homogeneity of the legal style and formal distinctions originating from rich contextual background. The study is conducted on the material of a custom-designed corpus of English legal texts, classified as secondary genres. Methodologically, the study makes use of the tenets of supervised search of digitalised corpora and automatic data extraction based on discrete units, subsequent identification of recurring longer contiguous and/or non-contiguous sequences, if any, built around the axis of specific verbal structures and finally qualitative comparative analysis of the material. The discussion presents sample data and focuses on the most salient categories, both quantitatively and qualitatively. The inductive approach confirms the formal divergencies in the communicative situation covered by the analysis. The findings encapsulate patterns and tendencies in the quantitative distribution of verbal structures depending on the authorship category. It may be concluded that authorship is a factor delineating distinctions as regards the repertoire of grammatical instruments exploited, which contributes to the specific stylistic profile of given authors. This shows that the thesis posed is verified positively and the study shows further, more detailed distinctions running through groups of subcategories distinguished within the authorship categories specified upon the start of the research. (shrink)

The purpose of this paper is to present some of the findings (which were reported on more extensively in earlier work) regarding the visibility of gender issues in the literature on selected information and communication technologies (ICTs) with a view to make predictions about potential ethical issues that the application of these ICTs may bring about in the future. On the basis of the analysis of around 100 published sources, which dealt with various aspects of selected ICTs, conclusions have been (...) drawn regarding gender issues and concerns that the applications of these ICTs may cause. The authors' analysis is theoretically informed by critical discourse analysis (CDA) which assumes that texts, both written and spoken, as well as other forms of symbolic representations, are indicative of social practices. Of particular methodological relevance was the survey of methods of text and discourse analysis presented in Titscher et al and especially the application of keyword search as a way to measure the prominence of each investigated method. This approach to literature surveying proved very useful in selecting analytic material: only those published sources on the selected four ICTs have been included in the survey, for which the analysis of keywords, abstracts and indexes of terms indicated authors' interest in gender issues. Findings - First, ICTs such as affective computing, ambient intelligence, and artificial intelligence, have been found to have the potential of positively affecting gender power relations and thus positively affecting gender balance in the areas of labour market related to ICT across EU countries and worldwide. Second, more research on the relationship between gender and ICT design, application and representation is needed, so as to enhance a better understanding of ethical issues resulting from unequal participation of women and men in all aspects of ICT production and implementation, which in itself is an ethical dilemma with which both the ICT business and legislators have to grapple. The paper offers insight into the relationship between the level of attention devoted to particular ICTs by ICT researchers, as evidenced in the reviewed literature, and the likelihood of the application of a particular ICT in the future, which is looked at and assessed from a gender perspective. (shrink)

The article examines the findings that allow us to date the first installation of the Serapieia A and B at Delos, according to material recovered in recent excavations. A study of the ceramics led to a revision of previously established positions: in particular, the construction date of the Serapieion B must now be brought back by a century, while the date of the Serapieion A seems to correspond to the one generally agreed upon, based on the chronology of the epigraphic (...) texts. Consequently, the issue of the discrepancy between the epigraphic data and the ceramic data with regard to the dating of the Serapieion B must be examined. (shrink)

Timeless Radcliffe: A Review of Ann Radcliffe, Romanticism and the Gothic - Tomasz Fisiak Yeats’s Genres and Tensions: A Review of Charles I. Armstrong’s Reframing Yeats: Genre, Allusion and History - Wit Pietrzak Review of Anna Pochmara’s The Making of the New Negro: Black Authorship, Masculinity, and Sexuality in the Harlem Renaissance - Antoni Górny “Artful Exaggeration” - Krzysztof Majer Interviews Bill Gaston Transcultural Theatre in the UK - Uilleam Blacker Talks to Joanna Kosmalska.

Timeless Radcliffe: A Review of Ann Radcliffe, Romanticism and the Gothic - Tomasz Fisiak Yeats’s Genres and Tensions: A Review of Charles I. Armstrong’s Reframing Yeats: Genre, Allusion and History - Wit Pietrzak Review of Anna Pochmara’s The Making of the New Negro: Black Authorship, Masculinity, and Sexuality in the Harlem Renaissance - Antoni Górny “Artful Exaggeration” - Krzysztof Majer Interviews Bill Gaston Transcultural Theatre in the UK - Uilleam Blacker Talks to Joanna Kosmalska.

The generic overgeneralization effect is an attested tendency to accept false universal generalizations such as “all eagles fly” or “all snakes lay eggs” as true. In this paper, we discuss the generic overgeneralization effect demonstrated by Polish adult speakers. We asked 313 native speakers of Polish to evaluate universal quantified generalizations such as “all eagles fly” or “all snakes lay eggs” as true or false. The control group of 107 respondents provided data on the acceptance rates of the corresponding generic (...) generalizations such as “eagles fly” or “snakes lay eggs”. By determining the impact of test fillers on the participants’ acceptance rates, the study aimed to identify the scope of the generic overgeneralization effect. We manipulated four conditions: the universal negative, positive, neutral, and generic control conditions. The results showed significant differences between the first two conditions, but neither the negative nor the positive condition differed from the neutral one. The overall acceptance rates of universal statements were 63% for the negative condition, 49% for the positive condition, 55% for the neutral condition, and 90% for the control group. Overall, the participants accepted universal quantified statements at high rates even when they were prompted to reject them. The results may be interpreted as another piece of evidence in support of the generic overgeneralization effect. (shrink)

This article is devoted to presenting the intermedia journalistic project called Out of Eden Walk and launched by American reporter Paul Salopek. Based on values such as journalistic reliability and the in-depth view of the reality, the project can be situated within the framework of the popular strands of slow journalism and slow travel. Salopek’s intention was to present Out of Eden Walk as an alternative to the rapidity of mass media communication and popular travel writing. The purpose of this (...) paper is to demonstrate the way in which Salopek uses media convergence mechanisms for creating an intermediary journalistic message, which is then distributed via various communication platforms based on both new media and traditional media. (shrink)

Rozważania o moralności i etyczności uczonych oraz wiedzy będącej efektem ich prac, sugerują, że twórcy i ich dzieła powinni być obdarzeni jakimiś wyjątkowymi predyspozycjami moralnymi, poznawczymi oraz intelektualnymi, a zatem muszą funkcjonować jakieś pożądane i akceptowane wzorce „cnót”, którymi powinien szczycić się uczony, a także sama nauka. Pojawia się pytanie, jakie miałyby one być? Powyższa kwestia jest interesująca w kontekście dyskursu kształtującego oblicze nauki nowożytnej, dyskursu, w którym formułowano oczekiwania, co do etyczności, moralności nauki i uczonych. Można byłoby powiedzieć, że (...) te oczekiwania mają znaczenie także i dzisiaj, mimo że zmieniła się nauka, społeczeństwa i ustroje oraz wymagania ludzi wobec nauki. Uprawianie nauki wymagało (i nadal wymaga) swobody twórczej. Jednakże instytucjonalizacja środowiska akademickiego zakładała podległość wobec władz, podległość, która generowała (i generuje) napięcie między potrzebą niezależności naukowej, a wymaganiami „sponsorów”. Także relacje między nauką, a polityką były przedmiotem rozważań wielu uczonych i filozofów, szczególnie gdy uwzględnimy aspekt moralności nauki i moralnej odpowiedzialności uczonych. Rozważania na ten temat są efektem lektury książki Richarda Holmesa Wiek cudów. Jak odkrywano piękno i grozę nauki, w której autor – opisując życiorysy uczonych, ale przede wszystkim ich dokonania oraz przeciwności, na jakie natrafiali – nieustannie podkreśla moralne i etyczne aspekty związane z osobowością uczonych i ich działalnością. (shrink)

As the recent Ebola outbreak demonstrates, visibility is central to the shaping of political, medical, and socioeconomic decisions. The symposium in this issue of the Journal of Bioethical Inquiry explores the uneasy relationship between the necessity of making diseases visible, the mechanisms of legal and visual censorship, and the overall ethics of viewing and spectatorship, including the effects of media visibility on the perception of particular “marked” bodies. Scholarship across the disciplines of communication, anthropology, gender studies, and visual studies, as (...) well as a photographer’s visual essay and memorial reflection, throw light on various strategies of visualization and legitimation and link these to broader socioeconomic concerns. Questions of the ethics of spectatorship, such as how to evoke empathy in the representation of individuals’ suffering without perpetuating social and economic inequalities, are explored in individual, national, and global contexts, demonstrating how disease visibility intersects with a complex nexus of health, sexuality, and global/national politics. A sensible management of visibility—an “ecology of the visible”—can be productive of more viable ways of individual and collective engagement with those who suffer. (shrink)

The aim of this article is to present the results of an analysis of the terminology of the Polish Criminal Code and its equivalents taken from three translations of the code into German. Scientific corpus includes Polish Criminal Code and the following three translations: DE-IURE-PL (2019), C.H. Beck (2012) and Max-Planck-Institut (1998). The method used is comparative legal analysis. The results of the analysis may find application in academic teaching and be used in the develop­ment of courses in legal translation.

Niccolo Machiavelli’s way of understanding the notions of good and evil rely on his theory of the origins of communities, according to which their basic structure is build around the figures of founders. Communities are kept alive by the constant effort make by their members to take care of common good and practice of crafts of peace. Forces opposed to the founders and disarraying the social life can be described as the figures on the continuum stretched between traitors, as Brutus (...) or Judas, and lazy-bones or cowards, parasiting on the fruits of common labor. This way of understanding the good and the evil has its roots in the age of Athenian Enlightenment – in the conception of virtue ethics based on workmanship metaphor as presented in the philosophy of sophists, Socrates, cynics and Aristotle. (shrink)