The associative theory of creativity states that creativity is associated with differences in the structure of semantic memory, whereas the executive theory of creativity emphasises the role of top-down control for creative thought. For a powerful test of these accounts, individual semantic memory structure was modelled with a novel method based on semantic relatedness judgements and different criteria for network filtering were compared. The executive account was supported by a correlation between creative ability and broad retrieval ability. The associative account (...) was independently supported, when network filtering was based on a relatedness threshold, but not when it was based on a fixed edge number or on the analysis of weighted networks. In the former case, creative ability was associated with shorter average path lengths and higher clustering of the network, suggesting that the semantic networks of creative people show higher small-worldness. (shrink)

Zonulin is a physiological modulator of intercellular tight junctions, which upregulation is involved in several diseases like celiac disease (CeD). The polyQ gliadin fragment binds to the CXCR3 chemokine receptor that activates zonulin upregulation, leading to increased intestinal permeability in humans. Here, we report a general hypothesis based on the structural connection between the polyQ sequence of the immunogenic CeD protein, gliadin, and enteric coccidian parasites proteins. Firstly, a novel interaction pathway between the parasites and the host is described based (...) on the structural similarities between polyQ gliadin fragments and the parasite proteins. Secondly, a potential connection between coccidial infections as a novel environmental trigger of CeD is hypothesized. Therefore, this report represents a promising breakthrough for coccidian research and points out the potential role of coccidian parasites as a novel trigger of CeD that might define a preventive strategy for gluten‐related disorders in general. Also see the video abstract here: https://youtu.be/oMaQasStcFI. (shrink)

Progress in Neuroscience advances rapidly and promises to change some of the basic concepts we have about ourselves. The field of Neuroethics is concerned with the resulting ethical implications. In this paper, we propose a framework to systematize the questions and positions in this context. We start with the discussion of three concrete cases around the topics of treatment/enhancement, personhood and privacy. For each case, we get a set of axes along which standpoints may vary. Finally, we generalize the particular (...) axes of each case and arrive at a three-dimensional coordinate system spanned by the axes of “Liberty of Denial”, “Liberty of Use” and “Scepticism”. With this, we hope to provide a common language simplifying interdisciplinary dialogue and communication with the public. (shrink)

Louis Althusser is the blemish on the field of political theory. His barely explored and partly forgotten contributions are nonetheless formative for contemporary critical thought. Interestingly, at their very core his interventions are based on his own extensive readings of early modern political thought. Therefore, this study traces Althusser's readings of Machiavelli, Hobbes, Locke, Rousseau and Montesquieu and is the first to do so. Building on this, the study demonstrates how Althusser's new foundation of Marxism, which is very much alive (...) today, arises from this part of his work. Thereby, it becomes visible how the post-Marxist paradigm, which Althusser's many important students further developed, is formed through his readings of the classic thinkers of the bourgeois state. (shrink)

The scientific and literary achievements of Albrecht von Haller were never questioned, but there has been much disagreement on the issue whether he was able to bring his scientific, philosophical, and religious beliefs into a harmonius synthesis. The recent and most comprehensive book on Haller by Richard Toellner (1971) suggests that Haller's thought possessed such a unity, and this judgment has remained unchallenged. This article reopens the question by painting out discrepancies between the Cartesian, Lockean, and Newtonian strands in Haller's (...) philosophy of science, as evidenced particularly by his pivotal essay on irritability and sensibility. In opposition to vitalism Haller postulated forces innate to matter, but out of religious concerns he feared materialism and was anxious to limit the power of such innate forces. (shrink)

Journal Name: Semiotica - Journal of the International Association for Semiotic Studies / Revue de l'Association Internationale de Sémiotique Volume: 2013 Issue: 196 Pages: 243-260.

This article contains an analysis of Warren Neidich’s early photographic work of 1997 until 2002. These works are linked to the extensive theoretical production of the artists who connect them to the concepts of the dispositif and apparatus respectively. The article provides a close description of the parameters of four pivotal work groups of Neidich’s early practice, Brain Wash, Double Vision, Shot Reverse Shot and Law of Loci. These works were realized with the aid of low-tech devices stemming from neuro-ophthalmology, (...) marking the interface between current neuro-philosophical discourses such as the plasticity of the brain, the apparati of visual, i.e. analog and digital, culture and the philosophy of memory. It is suggested that Neidich, even though he intervenes and contributes importantly to these intermingling discourses in a broad manner, is particularly interested in the degraded and infirm implementations of human vision in order to explore new sensations and habits of perception. (shrink)