Central sensitization refers to the increased responsiveness of nociceptive neurons in the central nervous system after repeated or sustained peripheral nociceptor activation. It is hypothesized to play a key role in the development of chronic pain. A hallmark of central sensitization is an increased sensitivity to noxious mechanical stimuli extending beyond the injured location, known as secondary hyperalgesia. For its ability to modulate the transmission and the processing of nociceptive inputs, attention could constitute a promising target to prevent central sensitization (...) and the development of chronic pain. It was recently shown that the experimental induction of central sensitization at both forearms of healthy volunteers using bilateral high-frequency electrocutaneous stimulation (HFS), can be modulated by encouraging participants to selectively focus their attention to one arm, to the detriment of the other arm, resulting in a greater secondary hyperalgesia on the attended arm as compared to the unattended one. Given the potential value of the question being addressed, we conducted a preregistered replication study in a well-powered independent sample to assess the robustness of the effect, i.e., the modulatory role of spatial attention on the induction of central sensitization. This hypothesis was tested using a double-blind, within-subject design. Sixty-seven healthy volunteers performed a task that required focusing attention toward one forearm to discriminate innocuous vibrotactile stimuli while HFS was applied on both forearms simultaneously. Our results showed a significant increase in mechanical sensitivity directly and 20 min after HFS. However, in contrast to the previous study, we did not find a significant difference in the development of secondary hyperalgesia between the attended vs. unattended arms. Our results question whether spatial selective attention affects the development of secondary hyperalgesia. Alternatively, the non-replication could be because the bottom-up capture of attention caused by the HFS-mediated sensation was too strong in comparison to the top-down modulation exerted by the attentional task. In other words, the task was not engaging enough and the HFS pulses, including those on the unattended arm, were too salient to allow a selective focus on one arm and modulate nociceptive processing. (shrink)

While the normative debate on European integration has addressed the importance of the construction of truly democratic institutions as well as the establishment of social rights at EU level, the role of progressive social movements has not been much debated. Building upon theorization and research in social movement studies, I argue that progressive social movements are indeed already contributing to the construction of European public spheres. Not one liberal (or bourgeois), public sphere but the proliferation of subaltern counterpublics could allow (...) for the participation of the excluded, giving them the possibility to make their political voice heard. Through different paths of Europeanization (in particular, domestication, externalization and transnationalization), progressive social movements have played an important role in the creation of a critical public sphere as, by contesting European institutions, they have contributed to make them (more) accountable, but have also developed collective identities at EU level and, with them, European public spheres. A main challenge is now to connect an emancipatory critical public to public institutions. (shrink)

The paper dealt with the control on political corruption in Italy, in particular with the reasons why most of the control mechanisms did not work for a long time, allowingfor the development of"tangentopoli". First of all, we briefly discussed the reasons why the controls ''from below"--that is, from citizens or electors--did not function in Italy: the pervasive occupation of the administration and the civil society by the political parties, as well as "secret" agreements between political parties in order to avoid (...) political scandals were discussed.The paper continued by analyzing two types of institutional control: the administrative controls and the judiciary controls. In the second part, we presented some main characteristics of the Italian public administration that hampered internal controls, the informal control of parties over the bureaucrats through clientelism and complicity in corruption being one among them. In the third part, we focused on the peculiar characteristics of a magistracy that enjoyed of a very high degree of format autonomy from the political power, but was "pushed" towards politics for reasons as different as complicity in corruption and the need to "substitute" for the weak policy making capacity of political parties. In the fourth part, we reviewed some reform bills to deal with the control of political corruption. (shrink)

Children’s sociocultural experiences in their day-to-day lives markedly play a key role in learning about the world. This study investigated parent–child teaching during early childhood as it naturally occurs in the home setting. Thirty-nine families’ naturalistic interactions in the home setting were observed; 1033 teaching sequences were identified based on detailed transcriptions of verbal and non-verbal behavior. Within these sequences, three domains of learning (knowledge, skills, and dispositions) and subtopics were identified and analyzed in relation to gender, child birth order, (...) context, teaching strategies, and learner response. Findings show knowledge, skills, and dispositions were taught equally, marked by the most prominent subtopics taught within each domain, including cognitive (skill), game rule (knowledge), and social rule (disposition). Further, mothers and fathers were found to teach their children equally, however, fathers taught knowledge more than mothers, whereas mothers taught dispositions more than fathers. Differences between domains of learning and subtopics also existed between mother’s and father’s teaching based on child birth order and gender. This study also assessed the contrast between teaching knowledge, skills, and dispositions by context, parent teaching strategies, and child learner response. Results support the notion that family interactions in the home setting set a stage for children’s rich informal learning experiences. Vygotskian sociocultural conceptions underpin this research and findings are discussed using this central theoretical lens. (shrink)

This volume contains essays that examine the optical works of Giambattista Della Porta, an Italian natural philosopher during the Scientific Revolution. Coverage also explores the science and technology of early modern optics. Della Porta's groundbreaking book, Magia Naturalis, includes a prototype of the camera. Yet, because of his obsession with magic, Della Porta's scientific achievements are often forgotten. As the contributors argue, his work inspired such great minds as Johanes Kepler and Francis Bacon. After reading this (...) book, researchers, historians, and students will have a better appreciation of this influential scientist. They will also gain a greater understanding of an important period in the history of optics. Readers will learn about Della Porta's experimental method, a process governed by the protocols, aims, and theoretical assumptions of natural magic. Coverage also discusses the material properties and limitations of optical technology in the early 17th century, based on a recently discovered Dutch spyglass. It also demonstrates how diagrams were instrumental in the discovery of the sine law of refraction. In addition, the book includes an in-depth analysis of previously untranslated Latin sources. This makes the material useful to historians of optics unfamiliar with the language. More than 70 illustrations complement the text. (shrink)

The study of vegetables represents one of the main topics in Bacon’s Sylva sylvarum. Not only in quantitative terms, because plants occupy about a third of the entire book, but the centuries on plants are among the most structured, and this reveals Bacon’s particular interest for the topic. The key to understanding Bacon’s interest can be found in both his Sylva sylvarum and the Historia vitae et mortis, where Bacon explains how the results of studying certain processes in plants can (...) be later transferred and applied to animals and humans. In the context of his discussion of nourishing foods and drinks, Bacon addresses the question of how nourishment gets assimilated in the body. One of the ways in which the... (shrink)

In questo lavoro si esplora la possibilità che l’inserzione dello sfruttamento umano all’interno del processo lavorativo e la conseguente apparizione sociale dell’uomo-merce abbiano lasciato tracce nell’opera di Dante. Si rintracciano così in una selezione di passi i problemi che questo processo impone alla nascente concezione dell’identità individuale e all’assunzione in una cornice ideologica ancora sacralizzata della distinzione fra ambito pubblico e ambito privato, che caratterizzerà il capitalismo fino a poche decadi fa.

I teoremi di Gödel suscitano un interesse sempre crescente nella riflessione filosofica contemporanea. Rimane però in discussione fra gli studiosi come si sia arrivati alla loro scoperta e quale sia il loro significato per il dibattito sui fondamenti delle scienze. Nel volume si ripercorrono le vicende che portarono alla formulazione dei teoremi di incompletezza, a partire dall’incontro tra von Neumann e Gödel al Congresso di Königsberg nel 1930, e si indaga, riferendosi in particolare al lavoro di von Neumann, sull’impatto che (...) questi teoremi hanno avuto per il progetto hilbertiano di fondazione della matematica e delle scienze più in generale. Ne risulta un’immagine delle indagini di Hilbert meno rigida di quella finora corrente, in linea con le più recenti acquisizioni della storiografia, e soprattutto più rispettosa della stessa prassi assiomatica, che oscillava per Hilbert tra ambizioni fondazionaliste e istanze pragmatiche. È stato von Neumann a rendere esplicita, dopo la scoperta dei teoremi di Gödel, quella che si può definire come la “svolta pragmatica” nell’assiomatica. Il libro propone inoltre un chiarimento riguardo alla scoperta di von Neumann del secondo teorema di incompletezza. (shrink)

In "La science et l’hypothèse" Henri Poincaré scrive: «Compito dello scienziato è ordinare; si fa la scienza con i fatti, come si fa una casa con le pietre; ma un cumulo di fatti non è una scienza, proprio come un mucchio di pietre non è una casa» . Oltre a richiamare qualcosa che a molti potrebbe persino apparire ovvio – cioè che la scienza non possa in alcun modo ridursi ad un mero agglomerato di fatti che il ricercatore registra in (...) ambito osservativo, ma richieda piuttosto un attento processo di elaborazione razionale sia in fase preventiva rispetto al contesto dell’esperienza, sia in fase di valutazione dei dati sperimentali raccolti – questa affermazione ha il merito di ricordarci qualcosa che spesso viene passato sotto silenzio, vale a dire il fatto che durante il nostro tentativo di comprendere il mondo si dia alla conoscenza una materia, un complesso di "oggetti", tale da risultare determinante nella costruzione e nella formulazione delle nostre teorie. Se questo è vero, si può quindi parlare di una materia, e di una forma da essa distinta, della conoscenza scientifica, sebbene con alcune precisazioni. Nel contributo si preciserà questa distinzione facendo riferimento alle assiomatizzazioni di alcune discipline scientifiche condotte nella prima metà del secolo scorso. (shrink)

Malebranche and the Search after Lost Identity. Legacy and Uncertainty of His Philosophy between the Eighteenth and Twentieth Centuries. Starting from the Œuvres complètes edited by Robinet, the article summarizes the vicissitudes through which the French historical scholarship with its leading figure Victor Cousin have restored the imagine and the correspondence of Malebranche, beginning with the dissemination of the original documents, conserved throughout the eighteenth century by P. Lelong, P. André, and finally P. Adry. In spite of his great historical (...) contribution, the French scholarship generally stressed an inadequate assessment of this philosophy, sharply suspected of spinozism, a judgment inherited by the handbooks of the history of philosophy edited between the XIX and the XX Century, as proved by the case of Grundriss der Geschichte der Philosophie by Überweg. The article concludes with three minimalist but creative readings of Malebranche by Proust, Heisenberg, Dalì. (shrink)

Negli anni che intercorrono fra la prima e l'ultima stesura della Scienza nuova vedono la luce in Europa le opere di Montesquieu e di Voltaire, di Lamettrie e di Hume, di Tindal e di Berkeley, di Morelly e di D'Alembert, Nell'Europa del suo tempo Vico fu senza dubbio un pensatore 'isolato'. Tale isolamento è stato di volta in volta interpretato come arretratezza e come capacità di divinazione - le pagine della Scienza nuova sono State interpretate come l'espressione tipica (...) di una rinnovata visione cristiana della storia o come un'anticipata polemica antilluministica e un precorrimento dei temi della cultura romantica e della filosofia di Hegel. 'Da un angoletto morto della storia', lavorando sui testi del secolo precedente, Vico affrontava comunque alcuni grandi problemi che resteranno al centro della cultura romantica, di quella positivistica, delle discussioni sullo storicismo. (shrink)

Una riflessione, a 400 anni dalla morte di Giovan Battista Della Porta Napoletano, uno dei grandi geni del Rinascimento.