The endangered species Tokudaia osimensis has the unique chromosome constitution of 2n = 25, with an XO/XO sex chromosome configuration (2n = 25; XO). There is urgency to preserve this species and to elucidate the regulator(s) that can discriminate the males and females arising from the indistinguishable sex chromosome constitution. However, it is not realistic to examine this rare animal species by sacrificing individuals. Recently, true naïve induced pluripotent stem cells were successfully generated from a female T. osimensis, and the (...) sexual plasticity of its germ cells was elucidated. This achievement constitutes the basis of an attractive research area, including embryonic fate determination, sex determination, and factor(s) that can replace the Y chromosome. In this essay, concrete strategies to conserve rare animal species and to reveal their specific characteristics using other compatible and abundant animals are proposed. -/- . (shrink)

In his early essay, “Must We Mean What We Say”, Cavell argues that the claims of ordinary language philosophers regarding “what we say when” are not empirical generalizations about a given group of speakers but are rather to be understood as measuring the limits of what counts as a coherent act of thinking and speaking. Cavell’s charge against the skeptic about the external world is that he seeks to think and speak beyond these limits. In this paper I compare Cavell’s (...) response to the skeptic to Davidson’s. Both base their responses on a broadly Kantian approach that appeals to the conditions under which thinking or speaking about objects is possible. On this approach the skeptic isn’t giving a false answer to an intelligible question, but rather, the question to which the skeptic is giving an answer is shown to be in some way unintelligible. But while Davidson’s critique of the skeptic is based on the conditions of ascribing meaning to one’s words, and contents to one’s beliefs, Cavell’s critique is based on the failure of the skeptic to mean the words he uses in the way that he needs. This difference expresses an underlying disagreement about the meaning of “meaning”: for Davidson the world comes into view through the meaning of our words and concepts, through the contents of our beliefs; for Cavell, the world comes into view through the agreement in “criteria” that are a condition of applying words and concepts to the world. This difference illuminates what Cavell calls “the truth of skepticism”: the idea that “my relation to the world and to others in general is not one of knowing”. (shrink)

This article explores what enables a space to become festive. We start by reviewing how the festive has been deeply connected with play, to the point of being considered a type of play, or more generally, a type of interaction. What enables the festive is the ability to interact with the substance on which participants feast. The question we will then explore in more detail is: given a subject matter from which to build a festive occasion or space, how do (...) we go about making it happen? How do we model the festive space? It is impossible to show that there is only one way of going about enacting the festive. For this reason, it is more productive to propose a model of how to achieve such task. The model that emerges in this article proposes that dismembering the festive substance, in a participatory way, facilitates its enactment. We then examine two cases of festive enactment in different mediums: the textual feast of Julio Cortázar’s novel Hopscotch that turns the printed page into a festive space, and the making of festive theatre, including the creation of the festive play Fire ’Scapes. (shrink)

This article examines how narratives mediate human interactions with environments to create a sense of place and identity. We begin with a review of the Greek poem Phaenomena to see how constellations brought a human dimension to the cosmos as well as a sense of predictability. A review of Jean-Paul Sartre’s Nausea illustrates the conception of indifferent space that erases the human presence, and how the imagination comes into play to fill the void. We examine how narratives work to model (...) aspects of environments and draw out meaning where before there was raw substance. Two seminal poems of Baudelaire then present a more subjective modeling of the environment. Pablo Neruda let his poetic vision be reflected in his three homes as protective playgrounds for his imagination. The article concludes that the models we examined are sheltering niches that help us feel at home in the world. As environments turn out to be more interactive, fragile, and complex than previously thought, our narratives also have to reflect on their impact on the sense of home they propose. (shrink)

Because of a strong similarity between two passages in Philo Judaeus, Cher. 37 and Her. 206, and the verb ejpikhrukeuvomai which is used in both loci is almost always completed by a dative. The Author proposes to read bivw/ instead of bivou at Cher. 37.

Substantial evidence supports the perspective that the people of Ancient Greece had a language for and some use for drugs, both for the purpose of medicine and poison; however, the question remains whether Ancient Greek civilization held a concept approximating what we today call drug addiction. This article explores the textual evidence for the use of two drugs, nepenthes and cannabis, in Ancient Greece. While the existence of nepenthes remains in doubt, the use of cannabis is well documented. Either drug (...) or both drugs may have been used in the rites of the Bacchic and Orphic mysteries, which might explain why there are so few references to these drugs in the Ancient Greek literature. (shrink)

The propositional fragment L 1 of Leniewski's ontology is the smallest class (of formulas) containing besides all the instances of tautology the formulas of the forms: (a, b) (a, a), (a, b) (b,). (a, c) and (a, b) (b, c). (b, a) being closed under detachment. The purpose of this paper is to furnish another more constructive proof than that given earlier by one of us for: Theorem A is provable in L 1 iff TA is a thesis of first-order (...) predicate logic with equality, where T is a translation of the formulas of L 1 into those of first-order predicate logic with equality such that T(a, b) = FblxFax (Russeltian-type definite description), TA B = TA TB, T A = TA, etc. (shrink)

Sensory symptoms are common in autism spectrum disorder. Previous studies have shown a positive correlation between sensory symptoms and internalizing problems; however, the role of the suffering due to sensory symptoms is not well understood. In the present study, we hypothesized that the relationship between sensory symptoms and internalizing problems in children is mediated by children’s and surrounding people’s suffering due to sensory symptoms. Parents of 113 students aged 6–15 years with and without ASD completed questionnaires about their children’s autistic (...) traits, sensory symptoms, suffering due to sensory symptoms, and internalizing problems. The results showed that autistic traits and sensory symptoms were distributed as a continuum throughout children with and without ASD. Therefore, we investigated the relationship among variables in children with and without ASD attending regular classes. Structural equation modeling indicated that those who scored higher on sensory symptoms demonstrated greater suffering due to sensory symptoms as predictors of internalizing problems. Our findings provide evidence for developing a support system that specifically reduces suffering due to sensory symptoms, especially for students in regular classes. (shrink)

Positive Youth Development (PYD) is an approach that promotes resilience and focuses on youth strengths rather than their weaknesses as done by the traditional deficit-based perspective. Research in Europe and North America show that developmental assets are associated with school success, psychological well-being, and lower health risks among youth and young adults. However, not much research has been done on these associations in Latin American contexts. The purpose of this research study is to assess the association between substance use behaviors, (...) such as drunkenness and the use of illicit drugs, and mental health, together with the mediating role of developmental assets representing youth strengths (e.g., social competence) and contextual resources (e.g., social support at home or school). Cross-national data was collected from Colombian (n= 210; 70.4% females) and Peruvian(n= 349; 66.5% females) 1st year university students. Results shed light on the protective role of developmental assets regarding substance use behaviors and mental well-being. Specifically, the results showed direct negative associations between developmental assets and substance use behaviors and positive associations of developmental assets with mental health indicators. Internal assets appear to be a stronger predictor of social, emotional, and psychological well-being compared to external assets. We did not find any statistical significance in the association of substance use behavior and mental health. We discuss implications regarding research, policy, and practice. (shrink)

Fidias López Valenzuela, Geógrafo de Profesión, al igual que muchos otros colegas en el desarrollo laboral, nos vemos enfrentados al concepto de Barrio. Innumerables han sido los intentos por llegar a un consenso sobre su definición, incluso visto por distintos profesionales como Arquitectos, Paisajistas y Geógrafos, entre otros; pero sin duda, a través de este Libro “Encantador era mi Barrio” se logra la esencia de lo que significa la palabra Barrio.El autor realiza una detallada descripción..