Severe acute respiratory syndrome‐coronavirus (SARS‐CoV)‐2′s origin is still controversial. Genomic analyses show SARS‐CoV‐2 likely to be chimeric, most of its sequence closest to bat CoV RaTG13, whereas its receptor binding domain (RBD) is almost identical to that of a pangolin CoV. Chimeric viruses can arise via natural recombination or human intervention. The furin cleavage site in the spike protein of SARS‐CoV‐2 confers to the virus the ability to cross species and tissue barriers, but was previously unseen in other SARS‐like CoVs. (...) Might genetic manipulations have been performed in order to evaluate pangolins as possible intermediate hosts for bat‐derived CoVs that were originally unable to bind to human receptors? Both cleavage site and specific RBD could result from site‐directed mutagenesis, a procedure that does not leave a trace. Considering the devastating impact of SARS‐CoV‐2 and importance of preventing future pandemics, researchers have a responsibility to carry out a thorough analysis of all possible SARS‐CoV‐2 origins. (shrink)

The article considers three episcopal assemblies held in Gaul, which the manuscript tradition has not preserved, all involved in doctrinal debates on grace and free will. The first two, the council of Arles and the synod of Lyon, took place in the second half of the fifth century and concerned the affair of the presbyter Lucidus. The third is the Council of Valence that met just before the Second Council of Orange (529), that is, the council that marks the “resolution” (...) of the conflict and also the only documented. With the idea that the history of the councils occupies important points in the reconstruction of the debate on grace and free will, even in the case of councils whose acts have not been transmitted, the article seeks to enhance these three events by reconsidering indirect sources. The episcopal meetings of Arles, Lyon, and Valence are, indeed, an integral part of the doctrinal work on grace and free will, which for about a century interested monastic and ecclesiastical circles in Gaul. Moreover, the recovery of their history restores well the complexity of the cultural, religious and political climate in which they took place. (shrink)

The workshop – presented by the director of a new center and the coordinator of an alliance intended to amplify and extend the influence of an established center – focused on the challenges involved in founding, growing, and sustaining centers for business ethics within university business schools. The discussion draws on experience at the Center for Business and Society, Leeds School of Business, University of Colorado, and the Center for Business Ethics, Bentley College and Bentley’s Alliance for Ethics & Social (...) Responsibility. (shrink)

The book offers insights on whether international law can shape the politics of the Security Council and, conversely, the extent to which the latter contribute to the development of international law. By providing a systematic analysis of the quantity and quality of international legal instruments referred to in the text of resolutions, the book reconstructs patterns of the Security Council's behavioural regularities and assesses them against the provisions of the United Nations Charter, which establishes its mandate. The analysis is divided (...) into three periods - the origins and Cold War period, post-Cold War period and the twenty-first century - and assesses the resolutions passed in each period by thematic category. The book argues that while international law plays an important role in shaping the politics of the Security Council, the Council's resolutions do not contribute significantly to the development of international law. (shrink)

L’agiografia fa parte dei generi letterari nei quali si esprimono con più libertà concezioni teologiche e morali non convenzionali, che ci svelano un Medioevo meno uniforme di come lo si immagina. L’articolo presenta alcuni esempi tratti da testi originari di diverse aree, dal Mediterraneo greco all’Irlanda, dall’epoca tardoantica al basso Medioevo. Di santi come il bretone Macuto, Epifanio di Salamina, i martiri edesseni e svariati abati irlandesi si narrano azioni mosse da permalosità, vendicatività, gelosia, competizione. Ancora nelle storie di santi (...) irlandesi, tra cui Brigida, compare il miracolo dell’eliminazione di un feto indesiderato dal grembo della madre. Il bolognese Procolo è celebrato per aver assassinato a sangue freddo il suo persecutore. La greca Irene è assunta fisicamente in cielo. Nella Navigatio Brendani, infine, la figura di Giuda è oggetto di una pietà del tutto eccezionale. Tutte queste anomalie generano alcune reazioni di censura e mitigazione nella ricezione e trasmissione dei testi, ma fondamentalmente sono accettate e conservate, testimoniando l’apertura e varietà dottrinale ancora possibile in epoca medievale. Hagiography is one of the literary genres in which unconventional theological and moral conceptions are most freely expressed, revealing a less uniform Middle Ages than we imagine. The article presents some examples from texts originating in different areas, from the Greek Mediterranean to Ireland, from late antiquity to the late Middle Ages. Saints such as the Breton Macutus, Epiphanius of Salamis, the Edessenian martyrs and several Irish abbots are described as acting out of touchiness, vindictiveness, jealousy and competition. In the stories of other Irish saints, including Bridget, we read the miracle of the elimination of an unwanted foetus from his mother’s womb. The Bolognese Proculus is celebrated for having cold-bloodedly murdered his persecutor. The Greek Irene is physically assumed into heaven. Finally, in the Navigatio Brendani, the figure of Judas is granted a quite exceptional piety. All these anomalies arouse some reactions of censorship and mitigation in the reception and transmission of these texts, but fundamentally they are accepted and preserved, testifying to the doctrinal openness and variety still possible in medieval times. (shrink)

Beaucoup de « géomètres » du XIXe siècle - Bernhard Riemann, Hermann von Helmholtz, Felix Klein, Riccardo De Paolis, Mario Pieri, Henri Poincaré, Federigo Enriques, et autres - ont joué un rôle important dans la discussion sur les fondements des mathématiques. Mais, contrairement aux idées d'Euclide, ils n'ont pas identifié «l'espace physique» avec« l'espace de nos sens». Partant de notre expérience dans l'espace, ils ont cherché à identifier les propriétés les plus importantes de l'espace et les ont posées à la (...) base de la géométrie. C'est sur la connaissance active de l'espace que les axiomes de la géométrie ont été élaborés ; ils ne pouvaient donc pas être a priori comme ils le sont dans la philosophie kantienne. En outre, pendant la dernière décade du siècle, certains mathématiciens italiens - De Paolis, Gino Fano, Pieri, et autres - ont fondé le concept de nombre sur la géométrie, en employant des résultats de la géométrie projective. Ainsi, on fondait l'arithmétique sur la géométrie et non l'inverse, comme David Hilbert a cherché à faire quelques années après, sans succès. (shrink)

This article examines the story of Jesus’ birth as it is presented in some of the so-called Apocryphal Infancy Gospels that have always aroused great interest in popular culture and in the arts. These texts describe the birth of Jesus by means of an important ‘narrative expansion’: the childbirth of Mary takes place in a cave, one or more midwives as well as two animals, the ox and the donkey, are added to the scene. These narratives do not relate the (...) preaching of Jesus, his death on the cross and his resurrection, but they present the event of his birth as a new beginning for all mankind. In doing so they reflect early Christian questions concerning Jesus’ nature. Examining some characteristic elements of this narrative development of the birth of Jesus, this article tries to show how this nativity may correspond to the construction of a myth. (shrink)

La autora realiza una aproximación crítica a la cultura jurídica de la izquierda, principalmente comunista, tomando como eje de su examen la posición interna o externa respecto del Estado adoptada por dicha cultura. El análisis se centra de manera especial en el problema de la "legislación de emergencia" y en sus consecuencias tanto en el tejido social como a efectos del problema de la legitimidad política.

The purpose of this essay is to elucidate the philosophical tools developed in George Steiner’s marvelous body of work. In his writings, he carries on a lucid observation and description of human spirit’s linguistic creation and formulation. His observations do not deviate from the way of a strict ethics inherited from ilustrated spiritual Judaism. His legacy about thought on language and his role as a contemporary culture’s critic leads us to a reflection on our continent and history. As an anthropological (...) work, it aims at a practical comprehension of gregariousness and to a psychic and physiological elucidation of the human phenomena. (shrink)

The ontogeny of the vertebrate retina has been a topic of interest to developmental biologists and human geneticists for many decades. Understanding the unfolding of the genetic program that transforms a field of progenitors cells into a functionally complex and multi‐layered sensory organ is a formidable challenge. Although classical genetic studies succeeded in identifying the key regulators of retina specification, understanding the architecture of their gene network and predicting their behavior are still a distant hope. The emergence of next‐generation sequencing (...) platforms revolutionized the field unlocking the access to genome‐wide datasets. Emerging techniques such as RNA‐seq, ChIP‐seq, ATAC‐seq, or single cell RNA‐seq are used to characterize eye developmental programs. These studies provide valuable information on the transcriptional and cis‐regulatory profiles of precursors and differentiated cells, outlining the trajectories that connect each intermediate state. Here, recent systems biology efforts are reviewed to understand the genetic programs shaping the vertebrate retina. (shrink)

L’Autrice si propone di tracciare la genealogia della posizione neoliberale, partendo soprattutto dai testi di Gary Becker. Il pensiero economico neoliberale è posto in relazione con la rivoluzione scientifica e l’operazione di matematizzazione della natura che da essa scaturisce. Questo percorso porterà poi a Jeremy Bentham, il cui sistema è spesso visto come antesignano degli studiosi neoliberali. Secondo la tesi sostenuta dall’Autrice, il neoliberalismo presenta il proprio sguardo come una neutra e scientifica descrizione del reale, sennonché in tale mossa si (...) annida pur sempre una tendenza normativa. È così che gli economisti neoliberali elaborano un sistema che è altresì prescrittivo, proponendo un modello che si pone sul piano politico; modello il quale viene qui designato con il nome di «utopia economica». (shrink)

Resumen: El presente artículo distingue principios epistemológicos que darían forma al oficio investigativo de la antropología. Se trata de presupuestos teóricos que encauzarían la práctica de una disciplina basada en un método de observación cualitativa, y en el registro sistemático de aquello observado bajo la forma de una huella subjetiva. En este trabajo se reflexiona sobre la postura ética implicada en el reconocimiento y explicitación de un locus investigativo, que sustentaría, a su vez, la articulación de un discurso aclaratorio con (...) carácter demostrativo. Un hipotético investigador será consciente de la representación multidimensional y subjetiva del fenómeno que observa, manteniéndose a resguardo de la acción interpretativa inmediatista y prescriptiva. En el marco conceptual que nos provee Bourdieu, la interpretación entrañará, en este caso, un “modus operandi” como expresión práctica y un “sentido común” como manifestación cultural. Se propone aquí una observación meditativa, que derivaría en la co-implicación del sujeto antropológico en aquello que intenta explicar.: This paper identifies epistemological principles that would come to define the task of anthropological research. These principles are theoretical assumptions which would inform the practice of a discipline based on a method of qualitative observation, and on the systematic recording of the things observed with a markedly subjective tone. In this study, I offer a proposal on the ethical stance implicit in the acknowledgement and explicitation of the locus of research, which would in turn underpin the articulation of an explanatory discourse that is demonstrative in nature. A hypothetical researcher would be aware of the multi-dimensional and subjective representation of the phenomenon observed and shun immediatist or prescriptive interpretations. In the conceptual framework offered by Bourdieu, interpretation in this case would entail a modus operandi as a practical expression and “common sense” as a cultural manifestation. What is proposed here is a meditative observation that would result in the co-involvement of the anthropological subject in that which the anthropologist seeks to explain. (shrink)

Este artículo contiene una reflexión, en primer lugar, sobre la vinculación que se establece entre la lengua de la madre –en su variedad experiencial cualitativa y determinaciones históricas– y el fenómeno de la locura y el dolor existenciales. En particular, se aborda el vínculo entre la mencionada lengua y el equívoco encauzamiento de una emocionalidad “no sabida”, esquivada o negada, hacia actos y acciones del habla. En segundo lugar, se observa la relación entre la lengua materna y formas de locura (...) existencial, en experiencias de fragmentación comunitario-familiar y de secuelas de exilios y diásporas del siglo XX. En tercer lugar, examina la experiencia, autobiográfica y crítica, de la escritura etnográfica y testimonial de la lengua. En cuarto lugar, ensaya una mirada fenomenológica de una ‘locura oral’, condicionada por secuelas de exterminios históricos. No es fácil notar, a primera vista, el ambiguo nexo de los sujetos plurales con la lengua materna, su reflejo en la psique colectiva como forma solapada de locura, monomanía, alienación y subjetividad fragmentada. Así como tampoco se advierte el impacto de esta particularidad en la acción comunicativa y convivencia lingüística gregaria. (shrink)

Resumen: Este artículo contiene una reflexión, en primer lugar, acerca de la vinculación que se establece entre la lengua de la madre -en su variedad experiencial cualitativa y determinaciones históricas- y el fenómeno de la locura y el dolor existenciales. En particular, se aborda el vínculo entre la mencionada lengua y el equívoco encauzamiento de una emocionalidad “no sabida”, esquivada o negada, hacia actos y acciones del habla. En segundo lugar, se observa la relación entre la lengua materna y formas (...) de locura existencial, en experiencias de fragmentación comunitario-familiar y de secuelas de exilios y diásporas del siglo XX. En tercer lugar, examina la experiencia, autobiográfica y crítica, de la escritura etnográfica y testimonial de la lengua. En cuarto lugar, ensaya una mirada fenomenológica de una “locura oral”, condicionada por secuelas de exterminios históricos. No es fácil notar, a primera vista, el ambiguo nexo de los sujetos plurales con la lengua materna, su reflejo en la psique colectiva como forma solapada de locura, monomanía, alienación y subjetividad fragmentada. Así como tampoco se advierte el impacto de esta particularidad en la acción comunicativa y convivencia lingüística gregaria.: This article contains, in the first place, a reflection on the link established between the mother's tongue -in its qualitative experiential variety and historical determinations- and the phenomenon of existential madness and grief, particularly with the distorted guiding of an “unidentified” emotionality, eluded or denied, towards speech acts. In the second place, the relationship between the mother’s tongue and different types of existential madness, in the context of community-family fragmentation experiences and sequels of exiles and diasporas of the twentieth century, is observed. In the third place, the autobiographical and critical experience of ethnographic and testimonial writing of the language is examined. Finally, this article aims to establish a phenomenological view of an ‘oral madness’, conditioned by sequels of historical extermination. It is not easy to notice, at first glance, the ambiguous nexus of plural subjects with the mother’s tongue, its reflection in the collective psyche as a concealed form of madness, monomania, alienation and fragmented subjectivity. Likewise, the impact of this particularity on communicative action and gregarious linguistic coexistence is neither easily noticed. (shrink)

Institutionalization occurs when organizations adopt policies and practices in an attempt to increase their legitimacy and competitive position. This process assumes that an organization's formal policies (macro‐level) are translated into organizational practices (micro‐level). This translation, however, can fail to occur, resulting in organizational decoupling and de‐institutionalization. Drawing on an institutionalization typology based on different levels of legitimacy (macro) and taken‐for‐grantedness (micro), the article draws on data from an assessment of theUnitedNations Global CompactLEADinitiative, assessing the extent to which this initiative is (...) being institutionalized in the member firms and examining the implications for theLEADinitiative and our thinking about institutionalization. (shrink)

La universidad adecuó la formación profesional hacia la virtualidad, adaptando con ello la teoría y la practica de las distintas materias, en ese nuevo contexto el objetivo de este estudio fue desarrollar un juego de simulación de selección de talento humano y describir la experiencia de juego en pandemia. Con un enfoque metodológico cuantitativo, diseño descriptivo no experimental transeccional, aplicado a estudiantes del VIII ciclo del curso de Gestión de Recursos Humanos. Se concluye que el juego simulado es una herramienta (...) que facilita el aprendizaje de forma virtual, asimismo contribuye con el aprendizaje del tema propuesto, de una forma organizada, dinámica y divertida. (shrink)

Recent research showed the potential benefits of robot-assisted therapy in treating children with Autism Spectrum Disorder. These children often have some form of Intellectual Disability too, but this has mainly been neglected by previous robotics research. This article presents an empirical evaluation of robot-assisted imitation training, where the child imitated the robot, integrated into the Treatment and Education of Autistic and related Communication handicapped Children program. The sample included six hospitalized children with different levels of ID, from mild to profound. (...) We applied mixed methods to assess their progress, during treatment and three months later. Results show increased Gross Motor Imitation skills in the children, except for those with profound ID and the therapists’ positive attitude towards the humanoid robot. Furthermore, the therapists suggest how a robot could be used to autonomously collect and analyze the information obtained in the rehabilitation training for a continuous evaluation of the participants. (shrink)

Today’s business students are tomorrow’s business leaders. To ensure they have skills in creating profitable, pro-social, ethical organizations, we need to consider alternative methods of teaching CSR. In this proposed symposium, we will present different approaches to international CSR/Service-Learning.

The current study aims at examining the relationship between the perfectionism two-factor model and burnout dimensions measured by using the BAT through a longitudinal study. A two-wave cross-lagged study was conducted using path analysis in SEM of 191 workers. Results confirmed the predictive role of perfectionistic concerns on the burnout dimensions, whereas perfectionistic strivings were not significantly related, suggesting that perfectionism should be monitored by employers and clinicians to prevent employee burnout. Limitations and future research directions are envisaged.

Desde 2019 un equipo de investigadoras de la Universidad Católica de Salta (Argentina) lleva adelante el proyecto de investigación “Ciclos de Complementación Curricular y Trayectorias Académicas en carreras de profesorados”, con el objetivo de comprender la incidencia del formato curricular en las trayectorias universitarias de estudiantes adultos que dan continuidad a su formación profesional en el campo de la docencia. Se trata de un estudio de casos con metodología cualitativa, que busca analizar el modo en que las condiciones y propuestas (...) institucionales favorecen u obstaculizan las trayectorias de los estudiantes en la cohorte 2018, considerando factores personales, institucionales y pedagógicos. (shrink)

What does Saussure really mean by “semiology”? This is the question we try to answer in this text. In fact, reading his writings and notes, we realize that Saussure uses the term “semiology” in different contexts and with different meanings. So the notion of “semiology” issued from his works is more complex than it seems because it undergoes several transformations throughout the development of Saussurian thought. The term “semiology” never appears in the texts published during in his lifetime, but we (...) find several mentions of this notion in the manuscript sources that make up the Saussurian corpus. While this term appears first during the period between 1881 and 1891, especially in all the documents known under the title of Phonétique, in the Gothic lessons, and in the manuscript “De l’essence double du langage”, the notion of “semiology” is presented to the public in the Cours de linguistique générale with a very precise meaning that has been taken up in Adrien Naville’s Nouvelle Classification des sciences. Then, after the publication of a large part of Saussure’s autograph writings, Ecrits de linguistique générale, we can return to this notion not only to trace its genesis, but also to better understand its complexity. And this is what we propose to do in this article. (shrink)