Sociotype is a concept that allows a more comprehensive understanding about biosociology of undiagnosed rare diseases (URD). Sociotype is related to a genotype and a phenotype and it is an expression of the individual life world in society. In this paper, semiotic and hermeneutic analysis of papers published and selected about URD is developed. Te perspective followed in this research is aligned with the works of Barbieri and Peirce. Papers with the most social content have been selected and those with (...) a more biomedical content have been rejected. Te semiotics analysis has been divided in genotypic, phenotypic and sociotypic, and related to the hermeneutical perspective. It has been possible to understand the basis of semiotics elements of URD. Te general conclusion is that URD is a particular sociotype with a determined set of social characteristics. Tis paper opens research on the biosemiotic and hermeneutic perspective about URD. (shrink)

In this research work we approach to the knowledge of undiagnosed diseases. These diseases are framed within the so-called rare diseases, because they are not frequent. They generate a series of conditions in the lives of the affected people and in their social relationships. This is the result of the semiotic break between the biological and the social code. This situation can force people with these diseases to be out of the social structure, and they also can be reduced their (...) capacity to make decisions. For this reason, it is necessary to develop semiotics bridges that connect the codes we have talked about. (shrink)

O presente artigo trata da influência exercida pela filosofia kantiana na actualidade a partir da chamada crise da Modernidade ilustrada. Os autores começam por analisar o posicionamento original kantiano, incidindo especialmente na sua concepção do criticismo e do transcendentalismo. Esta análise é feita a partir da perspectiva da aberta pela Kritik der Urteilskraft enquanto marco do sistema da razão, capaz de incorporar a finitude da mesma. Seguidamente são analisadas a recepção e a transformação do pensamento kantiano a partir de duas (...) correntes filosóficas actuais: o Racionalismo Crítico de Karl Popper e Hans Albert, e a Pragmática Transcendental da linguagem de KarlOtto Apel. Em ambos os casos se compara o seu modo próprio de incorporar as noções de crítica e transcendentalidade com a concepção original de Kant. (shrink)

AI research is being challenged with ensuring that autonomous agents learn to behave ethically, namely in alignment with moral values. Here, we propose a novel way of tackling the value alignment problem as a two-step process. The first step consists on formalising moral values and value aligned behaviour based on philosophical foundations. Our formalisation is compatible with the framework of (Multi-Objective) Reinforcement Learning, to ease the handling of an agent’s individual and ethical objectives. The second step consists in designing an (...) environment wherein an agent learns to behave ethically while pursuing its individual objective. We leverage on our theoretical results to introduce an algorithm that automates our two-step approach. In the cases where value-aligned behaviour is possible, our algorithm produces a learning environment for the agent wherein it will learn a value-aligned behaviour. (shrink)

El campo de la comunicación es un área de estudio de transcendencia global y con el desarrollo y auge de importantes tecnologías, han devenido en nuevos paradigmas sociales causales de los procesos de cambio impulsados por la mayor circulación de información y comunicación en un entorno global en el que la alfabetización mediática vista como un dominio progresivo promoviendo la comunicación, ha sido un desafío en su práctica y la investigación. El artículo ofrece una propuesta para incorporar en aulas universitarias (...) procesos de alfabetización mediática e informacional, revirtiendo así en prácticas atractivas y reales adaptadas a los nuevos retos educativos. (shrink)

In this paper we study the presence of elements related to Roman games in the work of the bishop Paulinus of Nola (355-431 AD). References to shows inhis work are not as abundant as they occurs among his contemporaries. Nevertheless, many of these references possess a great importance for us. Certainly, they are similar to other allusions made by his contemporaries; however they express the opinion of one of the most famous and prestigious bishops of the Late Antiquity about these (...) popular exhibitions. In his writings we can see his criticism of the waste of wealth in the organization of the Roman games, and also the use of a metaphorical language with ludical reminiscences whose origins go back to Paul of Tarsus. (shrink)

The Historia monachorum Syriae, written by Theodoret of Cyrrhus in 444 AD, contains a large quantity of sports metaphors in which the ascetic was presented as the “athlete of God”. The origin of this metaphor goes back to the epistles of Paul of Tarsus. Afterwards, there were many Christian writers who included it in their writings, although Theodoret undoubtedly exploited it in a much more intense way than other authors. His abundant use of this metaphor was due to the great (...) popularity enjoyed by athletic contests in the eastern Mediterranean well into the fifth century. Moreover, the partially profane education of Theodoret allowed him to give a specific terminology to his sports metaphors hardly documentable in other writers of Christian antiquity. (shrink)

La concepción más común de lo utópico es la de aquella entidad social que, por su misma perfección, no puede darse en la realidad. Esa concepción, que se ha impuesto en el pensamiento moderno y contemporáneo, suele aplicarse, asimismo, a la obra de Tomás Moro, Utopia, en la que se suele ver un estado perfecto pero relegado a la geografía fantástica de lo que podría ser pero nunca será, razón por la cual el humanista ha situado su sociedad en una (...) isla imaginaria. Pero esta concepción olvida los elementos auto-irónicos de la obra de Moro que excluyen una lectura que se pudiera basar en la dicotomía perfección ideal/imperfección real. Ensayamos una lectura, por tanto, más “hermenéutica” de la obra del escritor inglés. (shrink)

Este artículo trata de una inscripción constructiva omeya andalusí del año 387 / 4 enero 997-2 enero 998, hoy perdida, pero transmitida a través de un resumen castellano incluido en una lápida de 1259 "reparada" en 1575. Se intenta la restitución del texto árabe original y se estudian los hechos y los personajes documentados.

O presente artigo trata da influência exercida pela filosofia kantiana na actualidade a partir da chamada crise da Modernidade ilustrada. Os autores começam por analisar o posicionamento original kantiano, incidindo especialmente na sua concepção do criticismo e do transcendentalismo. Esta análise é feita a partir da perspectiva da aberta pela Kritik der Urteilskraft enquanto marco do sistema da razão, capaz de incorporar a finitude da mesma. Seguidamente são analisadas a recepção e a transformação do pensamento kantiano a partir de duas (...) correntes filosóflcas actuais: o Racionalismo Crítico de Karl Popper e Hans Albert, e a Pragmática Transcendental da linguagem de Karl-Otto Apel. Em ambos os casos se compara o sen modo próprio de incorporar as noções de crítica e transcendentalidade com a concepção original de Kant. /// The article addresses the influence of Kantian philosophy in contemporary thought from the view point of the crisis of illustrated Modernity. The authors start by analyzing the original Kantian position, whereby particular attention is given to his conception of criticism and transcendentalism. This analysis is worked out from the perspective of the Kritik der Urteilskraft as a frame for the system of reason, able to incorporate the finitude of reason itself This is followed by a detailed analysis of the reception and the transformation of illustrated thinking performed by two contemporary philosophical schools: Critical Rationalism (Karl Popper and Hans Albert), and Transcendental Pragmatics of language (Karl-Otto Apel). The authors of the article compare in each case the adoption of the notions of critique and transcendentality with the original use that Kant himself makes of them. (shrink)

In the context of solving large distributed constraint optimization problems, belief-propagation and incomplete inference algorithms are candidates of choice. However, in general, when the problem structure is very cyclic, these solution methods suffer from bad performance, due to non-convergence and many exchanged messages. As to improve performances of the MaxSum inference algorithm when solving cyclic constraint optimization problems, we propose here to take inspiration from the belief-propagation-guided decimation used to solve sparse random graphs. We propose the novel DeciMaxSum method, which (...) is parameterized in terms of policies to decide when to trigger decimation, which variables to decimate and which values to assign to decimated variables. Based on an empirical evaluation on a classical constraint optimization benchmarks, some of these combinations of policies, using periodic decimation, cycle detection-based decimation, parallel and non parallel decimation, random or deterministic variable selection and deterministic or random sampling for value selection, outperform state-of-the-art competitors in many settings. (shrink)

Chemosensation and mechanosensation cover an enormous spectrum of processes by which animals use information from the environment to adapt their behavior. For pragmatic reasons, these sensory modalities are commonly investigated independently. Recent advances, however, have revealed numerous situations in which they function together to control animals’ actions. Highlighting examples from diverse vertebrates and invertebrates, we first discuss sensory receptors and neurons that have dual roles in the detection of chemical and mechanical stimuli. Next we present cases where peripheral chemosensory and (...) mechanosensory pathways are discrete but intimately packaged to permit coordinated reception of external cues. Finally, we consider how chemical and mechanical signals converge in central neural circuitry to enable multisensory integration. These insights demonstrate how investigation of the interplay between different sensory modalities is key to a more holistic and realistic understanding of sensory‐guided behaviors. (shrink)

The aim of the present research was to assess elite student-athletes’ perception of the dual career during the lockdown caused by the coronavirus disease 2019 pandemic, compared with a group of elite student-athletes who could develop their dual career under normal conditions. A total of 150 elite athletes who were also undergraduate or postgraduate students self-completed the “Perceptions of dual career student-athletes ” questionnaire. From them, 78 did it during the mandatory lockdown period due to the state of emergency caused (...) by COVID-19 and 72 completed it in the previous year to Rio 2016 Olympic Games. The COVID-19 group was found to spend a significantly higher number of hours per week studying, while no significant differences were observed between groups in any training time variable. Student-athletes of the COVID-19 group showed better perception of whether their sport career could help them cope with their academic career and better general perception of remote learning and the use of tasks and videoconferencing as learning support tools. A lower percentage of athletes of the COVID-19 group than of the control group wished to continue with their sport career once they finished their studies. To conclude, student-athletes of the COVID-19 group show adaptations with regard to the organization of their studies and the importance they give to them and to the services provided by dual-career programs, compared with student-athletes from an ordinary pre-Olympic year. In general, student-athletes’ perception of the dual career is very positive. (shrink)

This study aimed to investigate the student-athletes' capability to face the academic, sport, and social challenges during the coronavirus disease 2019 (COVID-19) lockdown and to disclose novel aspects of dual careers. A 32-item online survey encompassing demographic characteristics, sport and university engagement, support and dual-career benefits, physical activity, sitting time, and the time deemed necessary to recover the previous level of performance was developed. Four hundred sixty-seven student-athletes (males: 57%, females: 43%) from 11 countries, competing in 49 different sports (individual: (...) 63.4%, team: 36.6%) at regional (17.5%), national (43.3%), and international (39.2%) levels, and enrolled at high school (21.9%) and university (78.1%) levels completed the survey. During the lockdown, the respondents decreased the time dedicated to sport and academics, although they maintained an active lifestyle. Student-athletes from countries under severe contagion were more likely to train at home, dedicate to academics, and receive support from the coach but less likely receive support from their teachers. With respect to their team sport counterparts, athletes competing in individual sports trained more and were more likely to receive support from their coaches. International athletes showed the highest training time and support from their coaches and as student-athletes. High school students received more support from their coaches and teachers, whereas university students were more likely considering dual careers useful to cope with the COVID-19 pandemic. This study substantiates the relevant role of competitive sports participation in the maintenance of active lifestyles, with student-athletes considering home training and e-learning valuable resources during the lockdown. Furthermore, their sport and academic commitments helped student-athletes cope with the emergency of the COVID-19 pandemic. (shrink)

The dual career allows elite athletes to attain their maximum competitive and academic performance, but the COVID-19 pandemic hindered their development and changed their perception of the importance given to the sporting and educational environment. For this reason, the aim of the present study was to determine the differences in the motivations and perceived barriers, the importance given to academic qualifications, and the perception of the dual career from a multifactorial perspective, of elite athletes according to sex, type of sport (...) practiced, job performance, time of sports career, type of athlete, and type of scholarship received. A total of 100 student-athletes participated in the research study by completing the “Perceptions of dual career student-athletes” questionnaire. The results showed that athletes from individual modalities and those who did not receive any scholarships described more barriers. In addition, women studied more because they enjoyed it ; athletes from individual modalities studied to work later ; athletes who do not work perceived a greater influence between study and sports performance ; at the beginning and at the best stage of their sports career, a greater influence of academics on performance was perceived ; and athletes who considered themselves professionals, and athletes who did not receive any scholarships, reported that the conciliation between sports and academic life was difficult. The results obtained point to the importance of dual career scholarships for student-athletes, as well as the need for the programs implemented for these athletes to consider sex, sport modality or type of scholarship granted. (shrink)

El objetivo de esta investigación, desarrollada en el contexto de educación virtual, fue mejorar las competencias investigativas de estudiantes universitarios. Este estudio cualitativo y de diseño investigación-acción se basó en un diagnóstico inicial con el que se identificó plagio académico, además de una autopercepción de nivel medio o bajo respecto de las habilidades investigativas de los alumnos. Durante la ejecución de las estrategias diseñadas, se aplicaron las técnicas de focus group y análisis documental de los ensayos estudiantiles. Se concluyó la (...) efectividad de las estrategias en la mejora de las competencias básicas, de búsqueda y análisis de información, y actitudinales. (shrink)

Desde un enfoque neuropsicológico, este estudio busca describir las operaciones cognitivas aplicadas durante la lectura. Este es un estudio de caso mixto, orientado a una muestra de 200 estudiantes de Enfermería. Para el recojo de información, se aplicó una prueba y un cuestionario de autopercepción lectora a los estudiantes; así como una guía de entrevista semiestructurada, dirigida a docentes. Entre los resultados, destaca que la velocidad lectora, la memoria y la atención impactan en el acto lector, además de las emociones (...) y los saberes previos. En conclusión, las operaciones cognitivas se vinculan directamente con los procesos asociados a la lectura. (shrink)

This paper studies an Umayyad Andalusi foundation inscription, dated 387/4 January 997-2 January 998, which is no longer extant but has been transmited in a summary in Castilian on a tablet dated 1259 and repaired in 1575. An attempt is made to deduce the original Arabic text, and the documented facts and persons are discussed.

Psychological flexibility is a key concept of acceptation and commitment therapy. This factor has been linked with psychological wellbeing and associated factors, such as quality of life, in cancer patients. These and other positive results of acceptation and commitment therapy in cancer patients found in previous research could be enhanced by using mhealth tools. A three-arm randomized superiority clinical trial, with a pre-post-follow-up repeated measures intergroup design with a 1:1:1 allocation ratio is proposed. A hundred and twenty cancer patients will (...) be randomly assigned to one of the following interventions: face-to-face ACT + mobile application, face-to-face ACT, and Waitlist control group. The primary expected outcome is to observe significant improvements in psychological flexibility acceptance and action questionnaire- II in the face-to-face ACT + app group, after comparing baseline and post-treatment scores, and the scores will remain stable in the two assessment points, 3 and 6 months after the intervention. Secondary expected outcomes are significant increasing scores in quality of life and post-traumatic-growth, and significant decreasing scores in anxiety and depression, insomnia and fatigue at the same assessment points. Also, it is expected that the scores of this group will be higher than the scores of the face-to-face ACT group and the waitlist control group. This study aims to assess the efficacy of a combined intervention for psychological flexibility and associated symptoms in cancer patients. The results of this protocol may help to consider the use of acceptation and commitment therapy and mhealth applications in cancer settings as a valid therapeutic choice.Clinical Trial Registration[www.ClinicalTrials.gov], identifier [NCT05126823]. (shrink)

En este trabajo intentamos un acercamiento a la filosofía social desarrollada por Simón Rodríguez en el conjunto de sus escritos reflexivos sobre la realidad político social hispanoamericana de la primera mitad del siglo XIX. Argumentamos que su examen de los problemas de las repúblicas hispanoamericanas constituyen una investigación crítica en el sentido moderno de este término, esto es, una investigación sobre las condiciones de posibilidad mismas de la comunidad como espacio del buen vivir. En este sentido, su trabajopropone la (...) aplicación de criterios, como el dominio del idioma español y el cambio de costumbres, para reformar la cultura. Se concluye que su filosofía social reivindica el papel de la comunidad en las necesarias transformaciones sociales que requiere la vida republicana en América del Sur, por supuesto, sin soslayar la importancia manifiesta que tienen los individuos como agentes concretos de cambio. Simon Rodriguez: his social philosophyIn thispaper we attemptan approach tosocialphilosophydeveloped bySimon Rodriguezon the set ofhis reflectivewritingsonLatin Americansocial and politicalrealityin the first halfof the nineteenth century.We argue thatconsiderationof the problemsof theAmerican republicsare acritical research, inthe modern sense ofthe term,that is,an inquiry intothe conditions of possibilityof this particular community of nationsasa good livingspace. In thissense, thepaper proposesthe applicationof certain criteria such asSpanishlanguage proficiencyand changingof habits,to reform theculture.We conclude thatsocialphilosophyclaims the roleof the community inthe necessarysocial changesrequirea republicin South America, of course, without ignoringthe importancethat individualsmanifestasindividualagentsof change. (shrink)

In Sociedades americanas en 1828, Simón Rodríguez describes and supports a republican attempt as a new way of government. Aware of the problem his project meant and warned against the accusation of being an utopian, he claims that the social republic would not be an utopia, as Tomas Moro imagined about, but the opportunity for the republics in South America to be the good place for an authentic social life. On the grounds that are described above, this paper examines (...) analytically and critically the relationships between republic and utopia in Simon Rodriguez. (shrink)

In Sociedades americanas en 1828, Simón Rodríguez describes and supports a republican attempt as a new way of government. Aware of the problem his project meant and warned against the accusation of being an utopian, he claims that the social republic would not be an utopia, as Tomas Moro imagined about, but the opportunity for the republics in South America to be the good place for an authentic social life. On the grounds that are described above, this paper examines (...) analytically and critically the relationships between republic and utopia in Simon Rodriguez. (shrink)

Abordamos aquí unos aspectos, posiblemente los menos conocidos, de la dilatada vida de Fray Diego de Deza, como son los orígenes de su linaje en la gallega Terra de Deza y el afincamiento durante la segunda mitad del siglo XIV de la que fue la rama familiar de Toro, su ciudad natal. No perteneciendo a la hidalguía de mayor abolengo y riqueza de los linajes allí establecidos, sus méritos personales le labraron un futuro prometedor, primero por la cátedra docente que (...) ocupó en Salamanca y sus altas dotes como maestro y, además, por la confianza que los Reyes Católicos depositaron en él al nombrarlo preceptor del malogrado príncipe heredero don Juan, lo que le hizo emprender una envidiable carrera tanto eclesiástica como por sus servicios a la Corona. Nuestro objetivo aquí no ha sido otro que vislumbrar sus relaciones parentales y sociales, obviando su brillante cursus honorum en ese doble rol de servicio al altar y al trono. (shrink)

Este trabajo comienza ofreciendo, a modo de «status quaestionis», una panorámica de la atención que se ha prestado a la obra ensayística de Sánchez Ferlosio, desde las lecturas propuestas en los años noventa del siglo pasado por autores del círculo de nuestro autor hasta los estudios y artículos aparecidos tras su muerte, en 2019. A continuación, se presentan algunas aportaciones relevantes de Ferlosio al pensamiento contemporáneo. Concretamente, se analiza el «aprecio por lo perecedero» como uno de estas aportaciones y, además, (...) se explica cómo este aprecio surge en el marco de una «actitud reflexiva ante el lenguaje». Por último, se procede a un balance crítico de las posiciones de Sánchez Ferlosio con respecto a los asuntos mencionados. (shrink)

Introduction: Loss of employment is an experience that is lived and interpreted differently depending on a series of individual variables, including the psychological resources available to the affected person, as well as their perception of their degree of employability. Losing one’s job can be one of the most painful and traumatic events a person has to withstand. Following a dismissal, the worker needs to overcome a period of emotional adaptation to the loss. But that period of grieving can also condition (...) the process of job search of the person, and be influenced by different variables, highlighting the age and work experience. The objective of this study is to analyze the relationship between intensity and type of affliction due to the loss of employment in older workers and their level of employability. Method: We carried out a descriptive, analytical, cross-sectional study. The sample consisted of 140 unemployed participants, from 19 to 65 years of age, users of job Orientation in the Public Employment Service of Andalusia (España). Of the total participants, 66 were unemployed and over 45 years of age. They all took the Labour Insertion Potential Assessment Test, and the Texas Inventory revised adapted to job loss Results: Significant differences are shown in the grieving process due to loss of employment between both groups, with the older unemployed living the process more intensely. In relation to the employability potential, differences are found between both groups in terms of availability, perceived difficulties and fears. Interrelationships between total grieving intensity and the importance that older jobseekers give to work are also indicated. Conclusion:Loss of employment and the psychological and health consequences of this situation are identified with those that arise in the grieving process. Older workers present a series of features that determine that their job loss grieving process is more intense and lasts longer than that of other younger workers, regardless of whether the job loss was recent or not. On the other hand, it is shown that the intensity of grieving is related to the decrease of certain variables that are part of the concept of employability. (shrink)

Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week multi-domain, single-blind, proof-of-concept randomized controlled trial examining the cognitive effect and underlying mechanisms of an aerobic exercise, computerized cognitive training and a combined groups compared to a waitlist control group. Adherence was > 80% for 82/109 participants recruited. In this study we report intervention-related changes in plasma biomarkers and structural-MRI and how they (...) related to changes in physical activity and individual variables and their potential role as mediators in the cognitive changes. Our results show that although there were no significant changes in molecular biomarker concentrations in any intervention group, changes in ICAM-1 and SDF1-α were negatively associated with changes in physical activity outcomes in AE and COMB groups. Brain volume changes were found in the CCT showing a significant increase in precuneus volume. Sex moderated the brain volume change in the AE and COMB groups, suggesting that men may benefit more than women. Changes in molecular biomarkers and brain volumes did not significantly mediate the cognitive-related benefits found previously for any group. This study shows crucial initial molecular and brain volume changes related to lifestyle interventions at early stages and highlights the value of examining activity parameters, individual difference characteristics and using a multi-level analysis approach to address these questions. (shrink)