The recognition of animal sentience in law has created high expectations but has not yet lived up to them. In some jurisdictions, the recognition of animal sentience has formed the basis of new legal obligations imposed on humans to protect animal interests. So far, however, its potential has been limited because legal officials have interpreted sentience narrowly, as mainly referring to pain. This article proposes identifying other animal characteristics to better serve animal interests, namely sociability and agency. These animal characteristics (...) could, like sentience, be legally recognized by legislatures and receive normative force from the courts. This article argues that the legal recognition of sociability and agency could address animal exploitation and killing. Animal sociability and agency are already implicitly recognized by the law of most Western states, making it easier for them to be explicitly recognized in the future. Although these characteristics are already found in the law, they have the potential to be more disruptive than sentience because they have never served as the basis for the legal protection of animals. In other words, their potential as protective tools remains underexplored and underexploited. Moreover, sociability and agency more intuitively suggest normative implications because of their demanding nature. Acknowledging that a being is social and agential implies recognizing her need for social relationships and ensuring that her choices are fulfilled. This research article provides antispeciesist scholars and activists with a critical overview of new concepts around which some may wish to rally, particularly since the legal recognition of sentience has shown limits in multiple jurisdictions. This article explores the potential of legally recognizing sociability and agency by taking examples from the lives of dogs, cows, cats, horses, northern gannets, and dolphins. (shrink)

Ribosome biogenesis includes the making and processing of ribosomal RNAs, the biosynthesis of ribosomal proteins from their mRNAs in the cytosol and their transport to the nucleolus to assemble pre‐ribosomal particles. Several stresses including cellular senescence reduce nucleolar rRNA synthesis and maturation increasing the availability of ribosome‐free ribosomal proteins. Several ribosomal proteins can activate the p53 tumor suppressor pathway but cells without p53 can still arrest their proliferation in response to an imbalance between ribosomal proteins and mature rRNA production. Recent (...) results on senescence‐associated ribogenesis defects (SARD) show that the ribosomal protein S14 (RPS14 or uS11) can act as a CDK4/6 inhibitor linking ribosome biogenesis defects to the main engine of cell cycle progression. This work offers new insights into the regulation of the cell cycle and suggests novel avenues to design anticancer drugs. (shrink)

This article examines the concept of ‘event’ and the manner in which it has been neglected in both ecocriticism and Hitchcock studies. Using The Birds (1963) to rethink the premises of ecocritics’ discussion of nature, animals, and disasters in cinema and Hitchcock scholars’ emphasis on representation and symbolism, the article argues that it has become imperative to philosophically foreground ‘events’ in light of the numerous contemporary films that revolve around them. Hitchcock’s film is shown to propose a renewed concept of (...) event, a concept that significantly departs from the two most influential conceptualisations of the event in post-1960 continental philosophy: those of Gilles Deleuze and Alain Badiou. Eschewing philosophical theories that equate the event with pure becoming or conceptualisations that characterise events as rupture and break, the film reveals a particular form of bird-event that posits relationality to address becoming and rupture simultaneously. Indeed, what distinguishes Hitchcock’s concept of event, contra Deleuze’s and Badiou’s, is that it emphasises relationality instead of pure continuity or radical rupture in the characterisation of corporeal or embodied individuation. Emphasising relationality helps understand the film’s deployment of a concept of event that departs from the aforementioned theorisations that exclude the human body (and therefore affect) from the event’s experiential import. Closely aligning bodies prior to and after the bird-events, The Birds ultimately discloses the paradox of body and event at the heart of contemporary event theory by way of linking or relating bodies and events, thus tapping into debates over embodiment and affect in cultural and media theory. Centering around modalities of evental experience rather than the controversial and endlessly debatable signification of the bird attacks, the analysis purports that the bird-event configures materiality only to reveal its relational and interstitial volatility. (shrink)

: As the fifth national bioethics commission has concluded its work and a sixth is currently underway, it is time to step back and consider appropriate measures of success. This paper argues that standard measures of commissions' influence fail to fully assess their role as public forums. From the perspective of democratic theory, a critical dimension of this role is public engagement: the ability of a commission to address the concerns of the general public, to learn how average citizens resolve (...) moral issues in healthcare, and to monitor public opinion on the topics addressed in the commission. Such a public forum role is supported by the critical literature within bioethics, which has deemed some commissions successful, supported more generally by the history of bioethics as a reform discourse that has brought socially important values into the medical domain, and supported more generally still by the example of the great social issues commissions of the 1960s. (shrink)

: In a 2004 article, we argued that bioethics commissions should be assessed in terms of their usefulness as public forums. A 2006 article by Summer Johnson argued that our perspective was not supported by the existing literature on presidential commissions, which had not previously identified commissions as public forums and that we did not properly account for the political functions of commissions as instruments of presidential power. Johnson also argued that there was nothing sufficiently unique about bioethics commissions to (...) make the public forum perspective particularly applicable. We respond by arguing that analysis of commissions' work as public forums fits well within the literature on commissions, especially on their agenda-setting functions, and that the political functions of commissions are often compatible with their functioning as public forums. We also demonstrate how the origins and concerns of bioethics make public forum analysis particularly applicable to bioethics commissions. (shrink)

Fisher’s ‘fundamental theorem of natural selection’ is notoriously abstract, and, no less notoriously, many take it to be false. In this paper, I explicate the theorem, examine the role that it played in Fisher’s general project for biology, and analyze why it was so very fundamental for Fisher. I defend Ewens (1989) and Lessard (1997) in the view that the theorem is in fact a true theorem if, as Fisher claimed, ‘the terms employed’ are ‘used strictly as defined’ (1930, (...) p. 38). Finally, I explain the role that projects such as Fisher’s play in the progress of scientific inquiry. (shrink)

Fisher’s ‘fundamental theorem of natural selection’ is notoriously abstract, and, no less notoriously, many take it to be false. In this paper, I explicate the theorem, examine the role that it played in Fisher’s general project for biology, and analyze why it was so very fundamental for Fisher. I defend Ewens and Lessard in the view that the theorem is in fact a true theorem if, as Fisher claimed, ‘the terms employed’ are ‘used strictly as defined’. Finally, I explain (...) the role that projects such as Fisher’s play in the progress of scientific inquiry. (shrink)

Fisher’s ‘fundamental theorem of natural selection’ is notoriously abstract, and, no less notoriously, many take it to be false. In this paper, I explicate the theorem, examine the role that it played in Fisher’s general project for biology, and analyze why it was so very fundamental for Fisher. I defend Ewens and Lessard in the view that the theorem is in fact a true theorem if, as Fisher claimed, ‘the terms employed’ are ‘used strictly as defined’. Finally, I explain (...) the role that projects such as Fisher’s play in the progress of scientific inquiry. (shrink)

Given his expertise in the classroom and in school, the cooperating teacher is essential to teacher training. Expectations towards him are coming from ministerial authorities (gouvernement du Québec, 2002, 2008), but also from student teachers (Caron, Portelance and Martineau, 2013). In order to meet these expectations, the cooperating teacher is strongly encouraged to enroll in a continuous training process leading to enhance his training practices. With the intention of supporting the development of the expected cooperating teacher’s competencies (Portelance, Gervais, (...) class='Hi'>Lessard, Beaulieu et al., 2008), a research funded by the Quebec Ministry of Education [1] uses a collaborative approach with cooperating teachers gathered in a community of practice. The members are engaged in a reflection process and a co-construction of meaning (Bourassa, Philion and Chevalier, 2007). Discussions focus on their training practices. The analysis of their purposes emphasizes the manifestations of interactional dynamics that favor their professional co-development. (shrink)