BackgroundCommunity Advisory Boards (CAB) have become essential organs of involving communities in HIV clinical trials especially in developing countries. However, limited empirical evidence exists on the role of CABs in low and middle-income countries including Tanzania. This study aims at exploring the role of CABs in community-based HIV clinical trials conducted in Tanzania.MethodologyWe adopted a phenomenological approach to purposefully select HIV clinical trial stakeholders. These included CAB members, researchers and Institutional Review Board (IRB) members in Tanzania. We conducted In-depth Interviews (...) (IDIs) with ten participants and three Focus Group Discussions (FGDs) with eighteen participants. The data were thematically analyzed with the aid of MAXQDA software version 20.2.1.ResultsThe findings indicate that at every stage of implementation of a community-based HIV clinical trial, a functioning CAB is important for its success. This importance is based on contextualization of the informed consent process and protocol, managing rumours in the community, weighing trial risks and benefits, sensitizing the community, assisting participant recruitment, tracing and retention. However, being perceived as financial beneficiaries than community representatives emerged as a challenge to CAB members. ConclusionThe study empirically indicates the need for functioning CABs in every stage of implementation of community-based HIV clinical trials. The roles of which are interwoven in serving research goals and protecting the interests of the community and that of trial participants. (shrink)

Opstellen over ideeën van historici als R. Fruin, J. Huizeinga en J.M. Romein.

This paper argues for the combination of political and socio-economic analysis in the study of early medieval gift-giving, specifically in the context of the late Merovingian Church. Gift-giving in this period is often viewed through a historiographical tradition strongly influenced by anthropological scholarship, which rarely considers any socio-economic reasoning behind the act – particularly in the case of ecclesiastical institutions and actors. This paper associates itself with the recent and growing answer to this position, and particularly to Ian Wood’s re-working (...) of Appadurai and Appadurai Breckenridge’s “Temple Societies” theory. It studies the political, social, and economic context and repercussions of gift-giving in the Life of Saint Eligius, a seventh-century craftsman, member of the Merovingian court, and subsequently bishop of the see of Noyon, in North-Eastern Francia. The paper analyses the vita in a threefold way: Firstly, it looks at the connection between political patronage and gift-giving through the saint’s relationship to the Merovingian court. Secondly, it considers the potential socio-economic effects of gift-giving on the ecclesiastical institutions described throughout the text, and on the societies around them. Thirdly, it interprets these aspects in the light of the political expansion of the Merovingian Church, and of its institutions, in eastern Gaul. (shrink)