Language understanding is one of the most important characteristics for human beings. As a pervasive phenomenon in natural language, metaphor is not only an essential thinking approach, but also an ingredient in human conceptual system. Many of our ways of thinking and experiences are virtually represented metaphorically. With the development of the cognitive research on metaphor, it is urgent to formulate a computational model for metaphor understanding based on the cognitive mechanism, especially with the view to promoting natural language understanding. (...) Many works have been done in pragmatics and cognitive linguistics, especially the discussions on metaphor understanding process in pragmatics and metaphor mapping representation in cognitive linguistics. In this paper, a theoretical framework for metaphor understanding based on the embodied mechanism of concept inquiry is proposed. Based on this framework, ontology is introduced as the knowledge representation method in metaphor understanding, and metaphor mapping is formulated as ontology mapping. In line with the conceptual blending theory, a revised conceptual blending framework is presented by adding a lexical ontology and context as the fifth mental space, and a metaphor mapping algorithm is proposed. (shrink)

Schizophrenia is a serious mental illness characterized by a disconnection between brain regions. Transcranial magnetic stimulation is a non-invasive brain intervention technique that can be used as a new and safe treatment option for patients with schizophrenia with drug-refractory symptoms, such as negative symptoms and cognitive impairment. However, the therapeutic effects of transcranial magnetic stimulation remain unclear and would be investigated using non-invasive tools, such as functional connectivity. A longitudinal design was adopted to investigate the alteration in FC dynamics using (...) a dynamic functional connectivity approach in patients with schizophrenia following high-frequency repeated transcranial magnetic stimulation with the target at the left dorsolateral prefrontal cortex. Two groups of schizophrenia inpatients were recruited. One group received a 4-week high-frequency rTMS together with antipsychotic drugs, while the other group only received antipsychotic drugs. Resting-state functional magnetic resonance imaging and psychiatric symptoms were obtained from the patients with schizophrenia twice at baseline and after 4-week treatment. The dynamics was evaluated using voxel- and region-wise FC temporal variability resulting from fMRI data. The pattern classification technique was used to verify the clinical application value of FC temporal variability. For the voxel-wise FC temporary variability, the repeated measures ANCOVA analysis showed significant treatment × time interaction effects on the FC temporary variability between the left DLPFC and several regions, including the thalamus, cerebellum, precuneus, and precentral gyrus, which are mainly located within the cortico-thalamo-cerebellar circuit. For the ROI-wise FC temporary variability, our results found a significant interaction effect on the FC among CTCC. rTMS intervention led to a reduced FC temporary variability. In addition, higher alteration in FC temporal variability between left DLPFC and right posterior parietal thalamus predicted a higher remission ratio of negative symptom scores, indicating that the decrease of FC temporal variability between the brain regions was associated with the remission of schizophrenia severity. The support vector regression results suggested that the baseline pattern of FC temporary variability between the regions in CTCC could predict the efficacy of high-frequency rTMS intervention on negative symptoms in schizophrenia. These findings confirm the potential relationship between the reduction in whole-brain functional dynamics induced by high-frequency rTMS and the improvement in psychiatric scores, suggesting that high-frequency rTMS affects psychiatric symptoms by coordinating the heterogeneity of activity between the brain regions. Future studies would examine the clinical utility of using functional dynamics patterns between specific brain regions as a biomarker to predict the treatment response of high-frequency rTMS. (shrink)

Schizophrenia is considered as a self-disorder with disordered local synchronous activation. Previous studies have reported widespread dyssynchrony of local activation in patients with SZ, which may be one of the crucial physiological mechanisms of SZ. To further verify this assumption, this work used a surface-based two-dimensional regional homogeneity approach to compare the local neural synchronous spontaneous oscillation between patients with SZ and healthy controls, instead of the volume-based regional homogeneity approach described in previous study. Ninety-seven SZ patients and 126 HC (...) were recruited to this study, and we found the SZ showed abnormal 2dReHo across the cortical surface. Specifically, at the global level, the SZ patients showed significantly reduced global 2dReHo; at the vertex level, the foci with increased 2dReHo in SZ were located in the default mode network, frontoparietal network, and limbic network ; however, foci with decreased 2dReHo were located in the somatomotor network, auditory network, and visual network. Additionally, this work found positive correlations between the 2dReHo of bilateral rectus and illness duration, as well as a significant positive correlation between the 2dReHo of right orbital inferior frontal gyrus with the negative scores of the positive and negative syndrome scale in the SZ patients. Therefore, the 2dReHo could provide some effective features contributed to explore the pathophysiology mechanism of SZ. (shrink)

In the employment relationship, organizational factors are the main factors that affect employee behavior. Especially for knowledge-based workers, it is even more crucial for organizations to give enough attention to their individual needs. Based on Existence, Relatedness, and Growth theory, this study constructs a moderated mediating model to explore how the impact of the employee–organization relationship on work engagement and work well-being of knowledge-based employees. In this study, existence–relatedness–growth need satisfaction is used as a mediator and the perceived symbiotic relationship (...) is used as a moderator. Data collected from 791 knowledge-based employees in higher education institutions from more than 20 provinces and cities in China are used to test the model. The results show that EOR has significant positive effects on WE and WWB. Need satisfaction for relatedness partially mediates the effects of EOR on WE and WWB. Need satisfaction for growth mediates the effect of EOR on WE while the mediating role of need satisfaction for growth between EOR and WWB is unsupported. The mediating role of need satisfaction for the existence of EOR on both WE and WWB is unsupported. The perceived symbiotic relationship moderates the relationship between EOR and WE and WWB. The findings are of theoretical significance in expanding the research field of EOR and providing a basis for organizations to implement EOR strategies. (shrink)

1. Ai di zong jiao yu ai di lun li--2. Ru jia di ren shu lun li--3. Mo jia di jian ai zhu yi--4. Jidu jiao dao de yu Ru Mo di lun li.

《老子汇校新解》以《四部丛刊》影汉河上公章句《老子道德经》宋刻本为底本，以光绪浙江书局重刻明华亭张子象本王弼《老子道德经注》、明正统《道藏》本傅奕校定《道德经古本》、马王堆帛书《老子》、郭店楚简《老子 》、唐景龙二年易州龙兴观道德经碑5种版本为主要参校本。通过对《老子》原文的重新校勘和注训，一方面尽可能的恢复其文本的旧貌，一方面大限度的揭示其文辞的本义，从而更好地去发现其所蕴含的哲学思想。.

PurposeThe purpose of this paper is to reveal the underlying mechanisms that drive young adults’ participation in micro-charity.Design/methodology/approachA case study, which formed a large online ethnographic project, was conducted in which the twin methods of participatory observation and in-depth interviews were used to access the experience of a selected group (n= 60) of college students.FindingsThe present paper identifies that young adults’ participation in micro-charity is mainly driven by three underlying mechanisms: the formation of a powerful environment for the distribution of (...) awareness of obligation, creation of trust towards others in distant or weak ties and symbolic construction of collective identity with a shared commitment.Originality/valueThis paper is an exploratory work which sheds new light on charity or other social entrepreneurship development in the social media era. Specifically, the connectivity of social media and the pre-existing relationships may work well together and lead to many positive outputs, including distributing awareness of social obligation, instilling social trust and strengthening social coherence. (shrink)

本文集收入了当代西方科学哲学的逻辑进程、意识经验的感受性和涌现、现象学与逻辑学、西方形而上学的实存哲学路线等共26篇文章。.

BackgroundBreast cancer patients are at elevated risk of depression during treatment, thus provoking the chance of poor clinical outcomes. This retrospective cohort study aimed to investigate whether integrating Chinese herbal medicines citation into conventional cancer therapy could decrease the risk of depression in the long-term breast cancer survivors.MethodsA cohort of patients aged 20–70 years and with newly diagnosed breast cancer during 2000–2008 was identified from a nationwide claims database. In this study, we focused solely on survivors of breast cancer at (...) least1 year after diagnosis. After one-to-one matching for age, sex, and baseline comorbidities, breast cancer patients who received and did not receive CHM treatment were enrolled. The incidence rate and hazard ratio citation for depression between the two groups was estimated at the end of 2012. A Cox proportional hazard model was constructed to examine the impact of the CHM use on the risk of depression.ResultsDuring the study period, the incidence rate of depression was significantly lower in the treated cohort than in the untreated cohort [8.57 compared with 11.01 per 1,000 person-years citation], and the adjusted HR remained significant at 0.74 in a Cox proportional hazards regression model. The corresponding risk further decreasing to 43% among those using CHM for more than 1 year.ConclusionFinding from this investigation indicated that the lower risk of depression observed in breast cancer patients treated with CHM, suggesting that CHM treatment should be considered for disease management toward breast cancer. Yet, the optimal administered dose should be determined in further clinical trials. (shrink)