That every response is also a stimulus has important implications for how we characterize the private experiences of both people and non-human animals. Acting as stimuli, responses, whether covert or overt, change the probability of subsequent responses. Hence, all behavior, covert and overt, is necessarily associative in some sense, and thinking may be characterized as “covert autochaining.” According to this view, animals capable of responding to temporally remote stimuli and to characteristics of their own bodies necessarily engage in (...) some form of associative thinking. This characterization of thinking necessarily presumes that private behavioral events adhere to at least some processes that occur in — and have been extensively studied in — overt behavior. To assume otherwise, as do Daniel Dennett, Robert Nozick, and others, is to be unnecessarily pessimistic both about the robustness of evolutionary processes and about our ability to explain complex human phenomena in rigorous empirical terms. (shrink)

Cigarette smoking and other addictive behaviors are among the main preventable risk factors for several severe and potentially fatal diseases. It has been argued that addictive behavior is controlled by an automatic-implicit cognitive system and by a reflective-explicit cognitive system, that operate in parallel to jointly drive human behavior. The present study addresses the formation of implicit attitudes towards smoking in both smokers and non-smokers, using a Go/NoGo association task, and behavioral and electroencephalographic measures. The GNAT assesses, via quantifying participants’ (...) reaction times, the strength of association between a target category and either pole of an evaluative dimension. EEG analysis is performed to determine the temporal course of the event-related potential components underlying Go/NoGo decisions and implicit attitude formation. Both smokers and non-smokers showed prolonged reaction times to smoking-related pictures when the pictures were coupled with positive evaluative words. This indicates negative implicit attitudes towards smoking in both groups alike at the time point of the behavioral response. However, only the non-smokers, not the smokers, were found to show a delay of the N200 component in the incongruent condition. This is interpreted as reflecting ambivalent or even positive implicit attitudes towards smoking in the smoker group at the time point of the N200. Our study thus provides evidence for the hypothesis that implicit attitudes are subject to changes within several hundred milliseconds after stimulus presentation, and can be altered in the course of their formation. (shrink)

Dysfunctional attentional control is observed in patients with mental disorders. However, there is no established neurophysiological method to assess attention in such patients. We showed a discrepancy in alpha-band power in the tasks that evoked internal and external attention event-related alpha-band power changes in healthy subjects during self-reflection and working memory tasks in a preliminary study. In this study, we aimed at elucidating event-related alpha-band power changes in healthy subjects during the tasks, addressing the shortcomings of the previous (...) study. Sixteen healthy volunteers were examined for the event-related power change during the tasks. The results demonstrated the discrepancy of alpha-band ERpow at 8, 10, and 12 Hz in the parieto-occipital area between the WM and SR tasks for a period between a target stimulus and a command stimulus, where a participant switched to internal attention from external attention according to the SR task and remained at external attention according to the WM task. The results suggest that alpha-band ERpow in this area is associated with the direction of attention in response to cognitive stimuli, indicating that the findings of ERpow during the two tasks would potentially aid in the clarification of the pathophysiology of the dysfunctional change in attention in patients with psychiatric disorders. (shrink)

The tremendous recent growth of the women's movement as a political force has been accompanied by an event of equal import to the academic world--the development of the discipline of women's studies. Colleges across the nation are establishing programs in this area. Women's Studies is a classroom anthology designed for use in these newly-introduced courses.

A set of images can be considered as meaningfully different for an observer if they can be distinguished phenomenally from one another. Each phenomenal difference must be supported by some neurophysiological differences. Differentiation analysis aims to quantify neurophysiological differentiation evoked by a given set of stimuli to assess its meaningfulness to the individual observer. As a proof of concept using high-density EEG, we show increased neurophysiological differentiation for a set of natural, meaningfully different images in contrast to another set of (...) artificially generated, meaninglessly different images in nine participants. Stimulus-evoked neurophysiological differentiation (over 257 channels, 800 ms) was systematically greater for meaningful vs. meaningless stimulus categories both at the group level and for individual subjects. Spatial breakdown showed a central-posterior peak of differentiation, consistent with the visual nature of the stimulus sets. Temporal breakdown revealed an early peak of differentiation around 110 ms, prominent in the central-posterior region; and a later, longer-lasting peak at 300–500 ms that was spatially more distributed. The early peak of differentiation was not accompanied by changes in mean ERP amplitude, whereas the later peak was associated with a higher amplitude ERP for meaningful images. An ERP component similar to visual-awareness-negativity occurred during the nadir of differentiation across all image types. Control stimulus sets and further analysis indicate that changes in neurophysiological differentiation between meaningful and meaningless stimulus sets could not be accounted for by spatial properties of the stimuli or by stimulus novelty and predictability. (shrink)

The Council on Ethical and Judicial Affairs of the American Medical Association examines physicians’ professional ethical responsibility in the event that the security of patients’ electronic records is breached.

Conflicts between target and distraction can occur at the level of both stimulus and response processing. However, the neural oscillations underlying occurrence of the interference in different levels have not been understood well. Here, we reveal such a neural oscillation modulation by combining a 4:2 mapping design (two targets are mapped into one response key) with a practice paradigm (pretest, practice, and posttest) when healthy human participants were performing a novel color-word flanker task. Response time (RT) results revealed constant (...) stimulus conflict (SC, stimulus incongruent minus congruent, SI-CO) but increased response conflict (RC, response incongruent minus stimulus incongruent, RI-SI) with practice. Event-related potential (ERP) results demonstrated stable P3 amplitude differences for the SI-CO in the centro-parietal region across practice, which may reflect maintenance of the stimulus processing; and significantly larger P3 amplitudes in the same region for the RI relative to SI trial type in posttest, which may reflect inhibition of the distraction response. Further, neural oscillatory results showed that with practice, the lower alpha band in the frontal region and the upper alpha band in the occipital-parietal region distinguished between stimulus- and response-conflicts, respectively, suggesting that practice reduces the alertness (sensitiveness) of the brain to conflict occurrence, and enhances stimulus-response associations. (shrink)

Using a classical conditioning technique, this study investigated whether nonconscious associative learning could be indexed by event-related brain activity . There were three phases. In a preconditioning baseline phase, pleasant and unpleasant facial schematics were presented in awareness . A conditioning phase followed, in which stimuli were presented outside awareness , with an unpleasant face linked to an aversive shock and a pleasant face not linked to a shock. The third, postconditioning phase, involved stimulus presentations in awareness (...) . Evidence for acquisition of a conditional response was sought by comparing suprathreshold pre- and postconditioning phases, as well as in the subthreshold conditioning phase itself. For the pre-postconditioning phase analyses, significant ERP component differences differentiating CS+ and CS− were observed for N1, P2, and especially P3. For the conditioning phase, significant differences were observed in the 100–400 ms. post-stimulus region reflecting a CS+ processing negativity. Brain activity does indeed index the acquisition of a conditional response to subthreshold stimuli. Associative learning can occur outside awareness. (shrink)

Explicit and implicit learning have been attributed to different learning processes that create different types of knowledge structures. Consistent with that claim, our study provides evidence that people integrate stimulus events differently when consciously aware versus unaware of the relationship between the events. In a first, acquisition phase participants sorted words into two categories , which were fully predicted by task-irrelevant primes—the labels of two other, semantically unrelated categories . In a second, test phase participants performed a lexical decision (...) task, in which all word stimuli stemmed from the previous prime categories and the primes were the labels of the previous target categories . Reliable priming effects in the second phase demonstrated that bidirectional associations between the respective categories had been formed in the acquisition phase , but these effects were found only in participants that were unaware of the relationship between the categories! We suggest that unconscious, implicit learning of event relationships results in the rather unsophisticated integration of the underlying event representations, whereas explicit learning takes the meaning of the order of the events into account, and thus creates unidirectional associations. (shrink)

Using a classical conditioning technique, this study investigated whether nonconscious associative learning could be indexed by event-related brain activity . There were three phases. In a preconditioning baseline phase, pleasant and unpleasant facial schematics were presented in awareness . A conditioning phase followed, in which stimuli were presented outside awareness , with an unpleasant face linked to an aversive shock and a pleasant face not linked to a shock. The third, postconditioning phase, involved stimulus presentations in awareness (...) . Evidence for acquisition of a conditional response was sought by comparing suprathreshold pre- and postconditioning phases, as well as in the subthreshold conditioning phase itself. For the pre-postconditioning phase analyses, significant ERP component differences differentiating CS+ and CS− were observed for N1, P2, and especially P3. For the conditioning phase, significant differences were observed in the 100–400 ms. post-stimulus region reflecting a CS+ processing negativity. Brain activity does indeed index the acquisition of a conditional response to subthreshold stimuli. Associative learning can occur outside awareness. (shrink)

This experiment used event-related potentials to study the tactile-visual information conflict processing in a tactile-visual pairing task and its modulation by tactile-induced emotional states. Eighteen participants were asked to indicate whether the tactile sensation on their body matched or did not match the expected tactile sensation associated with the object depicted in an image. The type of tactile-visual stimuli and the valence of tactile-induced emotional states were manipulated following a 2 × 2 factorial design. Electrophysiological analyses revealed a mismatched (...) minus matched negative difference component between 420 and 620 ms after stimulus onset in the negative tactile-induced emotional state condition. This ND420-620 component was considered as a sign of the cross-modal conflict processing during the processing of incongruent tactile-visual information. In contrast, no significant mismatched minus matched negative difference component was found in the positive tactile-induced emotional state condition. Together, these results support the hypothesis that a positive emotional state induced by a positive tactile stimulation improves tactile-visual conflict processing abilities. (shrink)

Inhibition, associated with self-efficacy, enables people to control thought and action and inhibit disturbing stimulus and impulsion and has certain evolutionary significance. This study analyzed the neural correlates of inhibition modulated by self-efficacy. Self-efficacy was assessed by using the survey adapted from the Motivated Strategies for Learning Questionnaire. Fifty college students divided into low and high self-efficacy groups participated in the experiments. Their ability to conduct inhibitory control was studied through Go/No-Go tasks. During the tasks, we recorded students’ brain (...) activity, focusing on N2 and P3 components in the event-related potential. Larger No-Go N2 amplitudes for the high self-efficacy group were found compared with the low self-efficacy group. Conflict detection as represented by N2 was modulated by self-efficacy, whereas conflict inhibition as represented by P3 was not modulated by self-efficacy. The highly self-efficacious students were more capable of detecting conflicts but not necessarily more capable of inhibiting action given that conflict was detected. Taken together, these findings offer neurophysiological evidence of the important regulatory role of self-efficacy in inhibitory control ability development. (shrink)

Previous research has shown that the content and frequency of mind-wandering episodes—the occurrence of thoughts that are both stimulus-independent and task-unrelated—are closely related to an individual’s future-related concerns. Whether this relationship is shaped by the affective changes that are usually associated with future-related concerns still remains unclear, however. In this study, we induced the anticipation of a negatively valenced event and examined whether the ensuing affective changes were related to the occurrence and content of mind-wandering during an unrelated (...) attentional task. We found that the increase in negative affect following concern induction predicted the general frequency of mind-wandering episodes. Furthermore, mind-wandering episodes specifically directed at the induced concern were related to a lower decrease in negative affect during the attentional task. These results suggest that the negative emotional impact of future-related concerns is an important factor to be taken into consideration for the subsequent occurrence of mind-wandering episodes, which might in turn be involved in the maintenance of negative affect over time. (shrink)

Long-term potentiation is one of the most extensively studied forms of neuroplasticity and is considered the strongest candidate mechanism for memory and learning. The use of event-related potentials and sensory stimulation paradigms has allowed for the translation from animal studies to non-invasive studies of LTP-like synaptic plasticity in humans. Accumulating evidence suggests that synaptic plasticity as measured by stimulus-specific response modulation is reduced in neuropsychiatric disorders such as major depressive disorder, bipolar disorders and schizophrenia, suggesting that impaired synaptic (...) plasticity plays a part in the underlying pathophysiology of these disorders. This is in line with the neuroplasticity hypothesis of depression, which postulate that deficits in neuroplasticity might be a common pathway underlying depressive disorders. The current study aims to replicate and confirm earlier reports that visual stimulus-specific response modulation is a viable probe into LTP-like synaptic plasticity in a large sample of healthy adults. Further, this study explores whether impairments in LTP-like synaptic plasticity is associated with self-reported subclinical depressive symptoms and stress in a healthy population. Consistent with prior research, the current study replicated and confirmed reports demonstrating significant modulation of visual evoked potentials following visual high-frequency stimulation. Current results further indicate that reduced LTP-like synaptic plasticity is associated with higher levels of self-reported symptoms of depression and perceived stress. This indicate that LTP-like plasticity is sensitive to sub-clinical levels of psychological distress, and might represent a vulnerability marker for the development of depressive symptoms. (shrink)

Studies on associative learning in normals and patients need appropriate dependent measures which are sensitive enough to reflect stimulus-specific responses and also consider the context in which the conditioning takes place. Patient's fear responses, once acquired, seem to be maintained by specific cognitive biases such as individual belief systems and a tendency to stay consistent with their previous judgments.

Drawing on the Ideal Standards Model, the current study investigated whether the relationship events and experiences that occur on a given day in romantic relationships were associated with partner evaluations. Individuals in a current romantic relationship completed daily measures of positive and negative relationship events and experiences and partner evaluations for seven consecutive days. As hypothesized, findings demonstrated that on a given day negative relationship events and experiences were associated with evaluating partners as falling short of mate ideals, while positive (...) relationship events and experiences were associated with evaluating partners as more closely meeting ideals. The findings demonstrate the importance of the relational context in evaluations of a partner against ideal standards. (shrink)