Initially “meaningless” and randomly generated sounds can be learned over exposure. This is demonstrated by studies where repetitions of randomly determined sound patterns are detected better if they are the same sounds presented on previous trials than if they are novel. This experiment posed two novel questions about this learning. First, does familiarization with a sound outside of the repetition detection context facilitate later performance? Second, does familiarization enhance performance when repeats are interleaved with distracters? Listeners were first trained to (...) categorize a unique pattern of synchronous complex tone trains from other tone trains with similar qualities. They were then tasked to detect repeated pattern presentations interleaved with similar distracters in 4.2 s long excerpts. The familiarized pattern, an unfamiliar pattern that remained fixed throughout, or patterns that were uniquely determined on each trial could be presented as repeats. FF patterns were learned at a faster rate and achieved higher repetition detection sensitivity than UF and UU patterns. Similarly, FF patterns also showed steeper learning slopes in their response times than UF patterns. The data show that familiarity with a “meaningless” sound pattern on its own can facilitate repetition detection even in the presence of distracters. Familiarity effects become most apparent in the potential for learning. (shrink)