Bridging the gap between medical and bioinformatics: An ontological case study in colon carcinoma
Computers in Biology and Medicine 36 (7):694--711 (2006)
Abstract
Ontological principles are needed in order to bridge the gap between medical and biological information in a robust and computable fashion. This is essential in order to draw inferences across the levels of granularity which span medicine and biology, an example of which include the understanding of the roles of tumor markers in the development and progress of carcinoma. Such information integration is also important for the integration of genomics information with the information contained in the electronic patient records in such a way that real time conclusions can be drawn. In this paper we describe a large multi-granular datasource built by using ontological principles and focusing on the case of colon carcinoma.Author's Profile
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References found in this work
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On the application of formal principles to life science data: A case study in the Gene Ontology.Jacob Köhler, Anand Kumar & Barry Smith - 2004 - In Proceedings of DILS 2004 (Data Integration in the Life Sciences), (Lecture Notes in Bioinformatics 2994). Berlin: Springer. pp. 79-94.
The cornucopia of formal-ontological relations.Barry Smith & Pierre Grenon - 2004 - Dialectica 58 (3):279–296.
The ontology of the Gene Ontology.Barry Smith, Jennifer Williams & Steffen Schulze-Kremer - 2003 - In AMIA 2003 Symposium Proceedings. Washington, DC: AMIA. pp. 609-613.
