Abstract

In Expériences sur le principe de la vie (Chez D’Hautel, Paris, 1812), Jean César Legallois, a French physician and physiologist, explored the basic regulatory framework of vital processes of warm-blooded animals. He decapitated rabbits and cut off their limbs in order to search for a seat of life that is located in the spinal cord. Through ligatures and artificial pulmonary insufflations, he kept the trunks of rabbits alive for some minutes. Legallois thus criticized models of organic order in which the spinal cord only mediates, like a gross nerve, between the brain and the body. He identified a certain section of the spinal cord that influences respiratory acts, and he also established a connection between the spinal cord and the movement of the heart. Further on, Legallois envisioned experiments that would extend the life-time of headless trunks through the infusion of arterial blood