El pasaje de la Elegía de Gray (PEG) en “On Denoting” es extremadamente obscuro y ha sido objeto de muy diversas interpretaciones. Aparentemente contiene una crítica devastadora contra la teoría de los conceptos denotativos que el propio Russell había postulado en The Principles of Mathematics (PM) (1903). En este artículo exponemos sucintamente dicha teoría semántica, examinamos detalladamente el pasaje en cuestión y exploramos algunas de las interpretaciones que pretenden desentrañar su sentido. Con ello mostramos, en primer lugar, que la crítica (...) se dirige directamente contra la teoría de PM; en segundo lugar, que no es posible hacer unos pocos cambios homogéneos para habilitar una lectura literal del pasaje; finalmente, que, si bien algunos de los argumentos que los intérpretes han aducido para abandonar la teoría de los conceptos denotativos son sólidos, no es obvio que todos ellos se encuentren en PEG. (shrink)

Background: Electroconvulsive therapy is one of the most effective treatments for major depressive disorder. Recently, there has been increasing attention to evaluate the effect of ECT on resting-state functional magnetic resonance imaging. This study aims to compare rs-fMRI of depressive disorder patients with healthy participants, investigate whether pre-ECT dynamic functional network connectivity network estimated from patients rs-fMRI is associated with an eventual ECT outcome, and explore the effect of ECT on brain network states.Method: Resting-state functional magnetic resonance imaging data were (...) collected from 119 patients with depression or depressive disorder, and 61 healthy participants, with an age mean of 52.25 years old. The pre-ECT and post-ECT Hamilton Depression Rating Scale were 25.59 ± 6.14 and 11.48 ± 9.07, respectively. Twenty-four independent components from default mode and cognitive control network were extracted, using group-independent component analysis from pre-ECT and post-ECT rs-fMRI. Then, the sliding window approach was used to estimate the pre-and post-ECT dFNC of each subject. Next, k-means clustering was separately applied to pre-ECT dFNC and post-ECT dFNC to assess three distinct states from each participant. We calculated the amount of time each subject spends in each state, which is called “occupancy rate” or OCR. Next, we compared OCR values between HC and DEP participants. We also calculated the partial correlation between pre-ECT OCRs and HDRS change while controlling for age, gender, and site. Finally, we evaluated the effectiveness of ECT by comparing pre- and post-ECT OCR of DEP and HC participants.Results: The main findings include depressive disorder patients had significantly lower OCR values than the HC group in state 2, where connectivity between cognitive control network and default mode network was relatively higher than other states, Pre-ECT OCR of state, with more negative connectivity between CCN and DMN components, is linked with the HDRS changes. This means that those DEP patients who spent less time in this state showed more HDRS change, and The post-ECT OCR analysis suggested that ECT increased the amount of time DEP patients spent in state 2.Conclusion: Our finding suggests that dynamic functional network connectivity features, estimated from CCN and DMN, show promise as a predictive biomarker of the ECT outcome of DEP patients. Also, this study identifies a possible underlying mechanism associated with the ECT effect on DEP patients. (shrink)

Se explora el desarrollo del campo de la Alfabetización Mediática y Digital en México, entre 2000 y 2021, mediante el análisis bibliométrico de publicaciones en Scopus y Web of Science, a partir del uso de frases sinónimas. Se observa una incipiente y dispersa producción científica en dicha área del conocimiento para el periodo de estudio.

This research advocates a strategy to mitigate or prevent further anthropogenic climate change and preserve natural resources. The strategy takes into account mechanisms of social and moral norms, which are innate in humanity due to millions of years of evolution. Social norms themselves are not innate, but the mechanisms to acquire them and implement them are. To slow down anthropogenic climate change global forces, inclusive of governments, NGOs, and collective humanity, should help indigenous peoples to protect their territories and property. (...) Important to the moral argument is highlighting the murder of Berta Cáceres, a Honduran environmental activist, in 2015 by military members of Honduras at the instruction of the Honduran joint chiefs of staff as well as the likely involvement of an energy company. To conclude, if global forces were to enforce protection of indigenous communities affected by the negative effects of urbanization and globalization, then there would be a mitigating effect on anthropogenic climate change. (shrink)

How can we picture the days of December 19th and 20th 2001 ? Where can we trace its origins and driving force? Which has been the leading subject? Are there any clues which enable us to recognize the movement as well as the obstacles it will have to overcome? The labour of the movement in Argentina does not only show the peculiarities of our history, but it also refutes the series of arguments on universal circulation asserting that the passage front (...) fordism to post fordism implies the inevitable destruction-disappearance of all social achievements that can be credited to the movements action in the past. The ungovernability that began in 1955 is today more serious than ever, because it is not the result nor of the incompetence of the succeeding governments nor of the imposition of the international financial centres, but, on the contrary, it is the result of the movement’s action through the years. (shrink)