The human loss of the sense of sacred has been driven by a mechanization of the world that privileges the mundane and the material. Yet the earliest surviving history of the human mind reveals a widespread, embodied human faculty for perception of the cosmos and an intimate human relation to the cosmos. This history hints of an origin story that may be partly recovered by sacred relics of human prehistory.

There is no direct, constant relationship between the anthropological and cultural aspects of modernity. Anthropologically modern peoples display a certain heterogeneity that is not unconnected with earlier peoples, and the culture produced by modern humans, which is also heterogeneous, is differentiated diachronically and according to territory. Though paleogenetic research seems to point us to a single, African source for modern peoples, who had replaced the pre-sapiens populations in Eurasia, this view is not completely proven or accepted. On the other hand, (...) paleo-genetic research has contributed to our relinquishing the hypothesis of a multiregional ‘total continuity’ of local pre-modern populations in the Old World. Indeed the theory of a partial replacement, by a migration ‘out of Africa’, appears to be getting increasingly plausible. This article deals with the problems of the origins of modern man from the points of view of anthropological, paleogenetic, paleoenvironmental and cultural approaches. (shrink)

Skeletons drawn from archaeological contexts provide a fund of data for assessing disease in general and timing of epidemics in particular in past societies. The bioarchaeological record presents an especially important perspective on timing of some of the world's most catastrophic diseases, such as leprosy, tuberculosis, plague (Black Death), and treponematosis. Application of new developments in paleogenomics and paleogenetics presents new opportunities to document ancient pathogens' DNA (for example, Black Death), track their history, and assess their beginning and end (...) points. Paleopathological documentation of disease terminus is complex, in part owing to circumstances where past communities experienced overlapping epidemics, such as leprosy and plague. For most settings, these syndemics-whereby there is an interaction between two or more epidemic diseases-both exacerbate and enhance the burden of morbidity in a community or region. Fundamental to understanding the severity and duration of epidemics is the consideration of multiple factors that simultaneously influence the severity and duration of the specific infectious diseases in a community or region, including poor oral health, under-nutrition, iron deficiency anemia, and elevated parasite load. In our view, comprehending the beginning, the middle, and the end of epidemics requires understanding the wider context of syndemics, the multiple challenging circumstances that undermine health and community stability, and how biosocial factors differentially affect the immune competence of individuals. This article provides several examples of the application of bioarchaeology and syndemics theory in achieving an understanding of how epidemics end. Pathogens continue to circulate, even after what appears to be the end. In effect, then, there is no “end,” just evolution of opportunistic pathogens and our ability (or not) to mitigate them. (shrink)

This essay surveys the evolution of historical scholarship on epidemic diseases in the Mediterranean/Islamicate world with a particular focus on plague. Temporally, it covers the scholarship on plague epidemics during the last 1,500 years, surveyed in three major pandemics: first, second, and third pandemics of plague. Geographically, it addresses the Mediterranean basin and its hinterland, including the Middle East and North Africa (MENA), the Anatolian peninsula, the Balkans, and occasionally drawing on adjacent areas such as the Black Sea region and (...) the Persian plateau. It outlines major trends and turning points in the modern historiography; reviews prevailing paradigms, contested issues, and emergent consensuses; and identifies methodologies, sources, and approaches. Whenever possible, it highlights contributions from paleogenetic and other scientific studies, with special reference to the diversity of opinions, actors, and materials in this highly controversial but vigorous field of study. The major goal of this essay is to reunite the divided historiographies of the Mediterranean world, which are typically studied separately in the case of Europe and the Islamicate world, with a view to underscoring their shared epidemiological experiences. (shrink)