Peeling the onion: NMDA dysfunction as a unifying model in schizophrenia

Behavioral and Brain Sciences 26 (1):93-94 (2003)

Abstract

N-methyl-d-aspartate receptor (NMDAR) dysfunction plays a crucial role in schizophrenia, leading to impairments in cognitive coordination. NMDAR agonists (e.g., glycine) ameliorate negative and cognitive symptoms, consistent with NMDAR models. However, not all types of cognitive coordination use NMDAR. Further, not all aspects of cognitive coordination are impaired in schizophrenia, suggesting the need for specificity in applying the cognitive coordination construct.

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References found in this work

Does the Chimpanzee Have a Theory of Mind?David Premack & G. Woodruff - 1978 - Behavioral and Brain Sciences 4 (4):515-629.
An Integrative Theory of Prefrontal Cortex Function.Earl K. Miller & Jonathan D. Cohen - 2001 - Annual Review of Neuroscience 24 (1):167-202.
The Astonishing Hypothesis.Francis Crick & J. Clark - 1994 - Journal of Consciousness Studies 1 (1):10-16.

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Citations of this work

Chaotic Itinerancy is a Key to Mental Diversity.Ichiro Tsuda - 2004 - Behavioral and Brain Sciences 27 (4):586-587.

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