In the 1820s, some years after smallpox vaccination had been introduced by most German states, physicians were faced with a seemingly new disease that they called false smallpox or varioloid . The paper deals with two epidemics of varioloid that spread in Würzburg between 1825 and 1829. The reports of eyewitnesses, case histories, and patients records from the Julius Hospital in Würzburg are analysed with respect to the state of vaccination in this region, and in consideration of the personal, practical (...) and scientific interests of the physicians involved. Special points of discussion are Schoenleins concept of epidemic disease, the role of contagionism, and the ambiguity of historical diagnosis. (shrink)

In early 19th‐century German medicine many doctors had a strong interest in historical pathology. They investigated the historical records of fevers and epidemics in detail, trying to find out how the changing influence of the epidemic constitution worked and hoping that history would help them to define specific disease entities. The underlying theory of this endeavour was that diseases undergo a historical development similar to the evolution of plants and animals. This paper tries to show that historical pathology was, in (...) its time, a legitimate attempt to solve the most urgent problems of empirical medicine. (shrink)