In a recent article J. Daryl Charles argues that a neurobiological account of morality is significantly limited. Although there is something right about this claim, it’s unclear what Charles thinks neuroscience tells us about our ability to make moral judgments and to be held blameworthy as moral agents. Regarding the true case of the stepfather who became a pedophile, I argue, against Charles, that it reveals the crucial role that the prefrontal cortex plays in the regulation of moral behavior. I (...) offer additional evidence that brain damage can encroach on our moral capacities, and I argue that it’s unreasonable to hold Smith responsible since he temporarily lacked the ability to comply with the moral obligation to avoid fulfilling his desires. (shrink)