Despite recent advances in the research related to air pollution and associated adverse cardiovascular events, the combined effects of air pollution, climate change, and SARS‐CoV‐2 infection on cardiovascular health need to be researched further. This Commentary addresses their impacts on cardiovascular health in the approximately 25 million people with a severe form of inherited hypercholesterolemia, called familial hypercholesterolemia (FH). The arterial endothelium in these individuals is potentially under multiple attacks caused by particles of both endogenous and exogenous origin. Thus, they (...) have a lifelong highly elevated level of circulating low density lipoprotein (LDL) cholesterol which drives premature atherosclerosis. The high levels of LDL particles, often associated with an elevated level of circulating lipoprotein(a) particles, are both capable of inducing and maintaining endothelial dysfunction. Such pre‐existing endothelial dysfunction can be exacerbated by exposure to SARS‐CoV‐2 viral particles, by exposure to fine particulate matter generated by climate change‐associated wildfires, and by dehydration during deadly heatwaves linked to the globally rising temperatures. The external factors can severely worsen the pre‐existing endothelial dysfunction, and thereby significantly increase the risk of a cardiovascular event in the exposed FH patients. (shrink)

Two Dogmas of Rorty's Pragmatism Here I discuss two controversial distinctions that have an essential role in Rorty's pragmatism: the distinction between descriptive and normative discourses, and the distinction between the private and public dimensions of human life. Neither of them is Rorty's novelty, but the way he stresses them is unique. The first is a central presupposition of his Philosophy and the Mirror of Nature (1979), while the other is the argumentative base of Contingency, Irony, and Solidarity (1989). I (...) will argue that the distinctions provide metaphilosophical tools for Rorty's pragmatism, and that our stance towards the latter depends on the plausibility of them. (shrink)

This paper reviews the research done in Finland on medical ethics in the last three years and published in four leading journals. The general characteristics of this area are discussed and some comments on its most conspicuous representatives are offered. The conclusion reached is that medical ethics in Finland is still in a rather embryonic stage of development, and that more systematic and theoretically sophisticated approaches are required. However, since many physicians have become interested in ethical questions, it can be (...) reasonably assumed that a more lively and theoretically grounded discussion will ensue in the near future. (shrink)

One of the interests in the Gapping construction is the headache it causes for those trying to get constituency structure right. On the assumption that Gapping, like other processes of sentence grammar, respects constituency, it is very hard to deliver the right constituents in cases such as (1). (1) a. Some consider him honest and others consider him pleasant. b. The faculty brought scotch to the party and the students brought beer to the party. c. The girls occasionally ate peanuts (...) and the boys occasionally ate breath mints. (Understand the material in strikeouts to be Gapped.) Everything else tells us that the Gapped strings in (1) should not form a constituent which excludes the material left behind. Yet, the fact that only when the verb Gaps may the other material too suggests just the opposite. That is, if we deny that the verb forms a constituent with the other material, and let Gapping apply to each of the elided constituents independently, we would have no way to express this dependency. If we let Gapping only elide constituents that house the verb, on the other hand, it follows. (shrink)