CRISPR and the Ethics of Gene Drive in Mosquitoes

Tina Rulli

dx.doi.org

CRISPR and the Ethics of Gene Drive in Mosquitoes

In David Boonin, Katrina L. Sifferd, Tyler K. Fagan, Valerie Gray Hardcastle, Michael Huemer, Daniel Wodak, Derk Pereboom, Stephen J. Morse, Sarah Tyson, Mark Zelcer, Garrett VanPelt, Devin Casey, Philip E. Devine, David K. Chan, Maarten Boudry, Christopher Freiman, Hrishikesh Joshi, Shelley Wilcox, Jason Brennan, Eric Wiland, Ryan Muldoon, Mark Alfano, Philip Robichaud, Kevin Timpe, David Livingstone Smith, Francis J. Beckwith, Dan Hooley, Russell Blackford, John Corvino, Corey McCall, Dan Demetriou, Ajume Wingo, Michael Shermer, Ole Martin Moen, Aksel Braanen Sterri, Teresa Blankmeyer Burke, Jeppe von Platz, John Thrasher, Mary Hawkesworth, William MacAskill, Daniel Halliday, Janine O’Flynn, Yoaav Isaacs, Jason Iuliano, Claire Pickard, Arvin M. Gouw, Tina Rulli, Justin Caouette, Allen Habib, Brian D. Earp, Andrew Vierra, Subrena E. Smith, Danielle M. Wenner, Lisa Diependaele, Sigrid Sterckx, G. Owen Schaefer, Markus K. Labude, Harisan Unais Nasir, Udo Schuklenk, Benjamin Zolf & Woolwine (eds.), The Palgrave Handbook of Philosophy and Public Policy. Springer Verlag. pp. 509-521 (2018)

@incollection{Rulli2018-RULCAT,
	author = {Tina Rulli},
	booktitle = {The Palgrave Handbook of Philosophy and Public Policy},
	editor = {David Boonin and Katrina L. Sifferd and Tyler K. Fagan and Valerie Gray Hardcastle and Michael Huemer and Daniel Wodak and Derk Pereboom and Stephen J. Morse and Sarah Tyson and Mark Zelcer and Garrett VanPelt and Devin Casey and Philip E. Devine and David K. Chan and Maarten Boudry and Christopher Freiman and Hrishikesh Joshi and Shelley Wilcox and Jason Brennan and Eric Wiland and Ryan Muldoon and Mark Alfano and Philip Robichaud and Kevin Timpe and David Livingstone Smith and Francis J. Beckwith and Dan Hooley and Russell Blackford and John Corvino and Corey McCall and Dan Demetriou and Ajume Wingo and Michael Shermer and Ole Martin Moen and Aksel Braanen Sterri and Teresa Blankmeyer Burke and Jeppe von Platz and John Thrasher and Mary Hawkesworth and William MacAskill and Daniel Halliday and Janine O?Flynn and Yoaav Isaacs and Jason Iuliano and Claire Pickard and Arvin M. Gouw and Tina Rulli and Justin Caouette and Allen Habib and Brian D. Earp and Andrew Vierra and Subrena E. Smith and Danielle M. Wenner and Lisa Diependaele and Sigrid Sterckx and G. Owen Schaefer and Markus K. Labude and Harisan Unais Nasir and Udo Schuklenk and Benjamin Zolf and Woolwine},
	pages = {509--521},
	publisher = {Springer Verlag},
	title = {Crispr and the Ethics of Gene Drive in Mosquitoes},
	year = {2018}
}

Rulli, Tina (2018). CRISPR and the Ethics of Gene Drive in Mosquitoes. In David Boonin, Katrina L. Sifferd, Tyler K. Fagan, Valerie Gray Hardcastle, Michael Huemer, Daniel Wodak, Derk Pereboom, Stephen J. Morse, Sarah Tyson, Mark Zelcer, Garrett VanPelt, Devin Casey, Philip E. Devine, David K. Chan, Maarten Boudry, Christopher Freiman, Hrishikesh Joshi, Shelley Wilcox, Jason Brennan, Eric Wiland, Ryan Muldoon, Mark Alfano, Philip Robichaud, Kevin Timpe, David Livingstone Smith, Francis J. Beckwith, Dan Hooley, Russell Blackford, John Corvino, Corey McCall, Dan Demetriou, Ajume Wingo, Michael Shermer, Ole Martin Moen, Aksel Braanen Sterri, Teresa Blankmeyer Burke, Jeppe von Platz, John Thrasher, Mary Hawkesworth, William MacAskill, Daniel Halliday, Janine O’Flynn, Yoaav Isaacs, Jason Iuliano, Claire Pickard, Arvin M. Gouw, Tina Rulli, Justin Caouette, Allen Habib, Brian D. Earp, Andrew Vierra, Subrena E. Smith, Danielle M. Wenner, Lisa Diependaele, Sigrid Sterckx, G. Owen Schaefer, Markus K. Labude, Harisan Unais Nasir, Udo Schuklenk, Benjamin Zolf & Woolwine (eds.), The Palgrave Handbook of Philosophy and Public Policy. Springer Verlag. pp. 509-521.

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Abstract

CRISPR Cas9-powered gene drive allows for the rapid alteration of malaria-causing mosquitoes to spread an infertility gene or resistance to malaria among their species. Malaria eradication would be a great boon to human health. But many are concerned with driving genetic changes through a natural species. This chapter catalogs objections to the use of gene drive in mosquitoes for eradicating malaria. In-principle objections to gene drive use are not compelling. The most urgent concerns are related to the safety of the technology for the environment and human health. Philosophers play a critical role in working along scientists to develop risk/benefit models that weigh the reasons for and against gene drive to eradicate malaria based on our best scientific knowledge and rigorous normative reasoning.

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Tina Rulli

University of California, Davis

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10.1007/978-3-319-93907-0_39

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Applied ethics	Epistemology	History of Western Philosophy	Meta-ethics	Metaphysics	Normative ethics
Philosophy of biology	Philosophy of language	Philosophy of mind	Philosophy of religion	Science Logic and Mathematics	More ...

CRISPR and the Ethics of Gene Drive in Mosquitoes

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