Timing models of reward learning and core addictive processes in the brain

Behavioral and Brain Sciences 31 (4):457-458 (2008)
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Abstract

People become addicted in different ways, and they respond differently to different interventions. There may nevertheless be a core neural pathology responsible for all distinctively addictive suboptimal behavioral habits. In particular, timing models of reward learning suggest a hypothesis according to which all addiction involves neuroadaptation that attenuates serotonergic inhibition of a mesolimbic dopamine system that has learned that cues for consumption of the addictive target are signals of a high-reward-rate environment

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Time, rate, and conditioning.C. R. Gallistel & John Gibbon - 2000 - Psychological Review 107 (2):289-344.

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