The human fovea is known for its distinctive pit‐like appearance, which results from the displacement of retinal layers superficial to the photoreceptors cells. The photoreceptors are found at high density within the foveal region but not the surrounding retina. Efforts to elucidate the mechanisms responsible for these unique features have ruled out cell death as an explanation for pit formation and changes in cell proliferation as the cause of increased photoreceptor density. These findings have led to speculation that mechanical forces (...) acting within and on the retina during development underly the formation of foveal architecture. Here we review eye morphogenesis and retinal remodeling in human embryonic development. Our meta‐analysis of the literature suggests that fovea formation is a protracted process involving dynamic changes in ocular shape that start early and continue throughout most of human embryonic development. From these observations, we propose a new model for fovea development. (shrink)

PurposeThis study investigated the impact of age and myopia on visual form perception among Chinese school-age children.MethodsThis cross-sectional study included 1,074 students with a mean age of 12.1 ± 4.7 years. The mean spherical equivalence refraction of the participants was −1.45 ± 2.07 D. All participants underwent distance visual acuity, refraction measurement and local and global visual form perception test including orientation, parallelism, collinearity, holes and color discrimination tasks.ResultsThe reaction times of emmetropes were slower than those of myopic and high (...) myopic groups on both local and global discrimination tasks. A reduction in reaction times was found with increasing age on both local and global discrimination tasks. Age was significantly associated with both local and global visual perception performance after adjusting for gender, visual acuity and SER.ConclusionsThis study revealed that both local and global visual perception improve with age among Chinese children and that myopes seem to have better visual perception than emmetropes. (shrink)