Fragile kingdoms of innumerable organisms and rich beauty, forests today are both our most plentiful and our most endangered natural resource. Understanding their workings and how to sustain them is imperative to ensuring the future of humanity. John Berger urges us to learn what can be done to preserve these treasures, and he offers here a compelling guide to the complex issues surrounding forest preservation. An expanded and revised version of Berger’s bestselling Understanding Forests, Forests Forever offers a clear and (...) readable survey of forest history and management. Berger draws upon diverse sources in law, ecology, economics, politics, and anthropology to argue that ecology, rather than the marketplace, should be the driving force behind forest management. Historical case studies of forests worldwide support this contention, the book reveals, as does the history of governments’ forest policy. Keeping pace with today’s issues, Berger critically evaluates government policy over the last seven years, including a contrast between the destructive policies of the Bush Administration and model programs instituted by the Canadian Boreal Initiative and others. Ultimately, he offers us the guiding principles of sustainable forestry as an answer to the ever-increasing demand for wood products. Anchoring the account are galleries of breathtaking full-color images of trees, forest, wildlife, and other forestry subjects taken by the world’s leading nature photographers. A concise and wholly readable account, Forests Forever issues a call to arms for all those concerned with preserving and managing the world’s forests today. (shrink)

Perlecan is a ubiquitous proteoglycan of basement membrane and vascularized tissues but is also present in articular cartilage, meniscus and intervertebral disc, which are devoid of basement membrane and predominantly avascular. It is a prominent pericellular proteoglycan in the transitory matrix of the cartilaginous rudiments that develop into components of diarthrodial joints and the axial skeleton, and it forms intricate perichondrial vessel networks that define the presumptive articulating surfaces of developing joints and line the cartilage canals in cartilaginous rudiments. Such (...) vessels have roles in the nutrition of the expanding cell numbers in the developing joint. Perlecan sequesters a number of growth factors pericellularly (FGFs, PDGF, VEGF and CTGF) and through these promotes cell signalling, cell proliferation and differentiation. Perlecan also interacts with a diverse range of extracellular matrix proteins, stabilising and organising the ECM, and promoting collagen fibrillogenesis. Perlecan is a prominent pericellular component of mesenchymal cells from their earliest developmental stages through to maturation, forming cell–cell and cell–ECM interconnections that are suggestive of a role in mechanosensory processes important to tissue homeostasis. BioEssays 30:457–469, 2008. © 2008 Wiley Periodicals, Inc. (shrink)