In this paper I argue that despite the philosophical, theological and cultural challenges, it is still possible to maintain, in a legitimate and critical way, a worldview that is coherent, unified, comprehensive and meaningful. I believe that the philosophical theology of KarlRahner offers just such a perspective. Hence, this paper explored the extent to which Karl Rahner’s understanding of the unity of matterand spirit, expressed in his integration of theology and evolution, can serve as the foundation for a more (...) comprehensive and integratedunderstanding of reality. I endeavored to provide a preliminary assessment of the adequacy of this integration by evaluating its abilityto respond to some of the important challenges to Christian theism raised by the American philosopher Daniel Dennett. By showingthat Rahner’s integration of theology and evolution can respond adequately to these challenges, the paper provides a promising firststep toward a more comprehensive investigation. (shrink)