Coding sequences: A history of sequence comparison algorithms as a scientific instrument

Perspectives on Science 19 (3):263-299 (2011)
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Abstract

Historians of molecular biology have paid significant attention to the role of scientific instruments and their relationship to the production of biological knowledge. For instance, Lily Kay has examined the history of electrophoresis, Boelie Elzen has analyzed the development of the ultracentrifuge as an enabling technology for molecular biology, and Nicolas Rasmussen has examined how molecular biology was transformed by the introduction of the electron microscope (Kay 1998, 1993; Elzen 1986; Rasmussen 1997). 1 Collectively, these historians have demonstrated how instruments and other elements of the material culture of the laboratory have played a decisive role in determining the kind and quantity of ..

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