Abstract
I defend the thesis that, if there are substances, substance causation (i.e., causation by substances) is the only sort of causation in the universe – or the only fundamental sort. Subsequently, I develop an account of substance causation that is partly grounded on a peculiar interpretation of absolute change (i.e., of entities' coming and ceasing to be) and qualitative change, on some ontological assumptions about modes (i.e., individual properties that ontologically depend on their bearers) and powers. Finally, I reply to some objections against substance causation in general (e.g., C. D. Broad's objection against causes' being non-essentially-dated entities) and to some possible objections against my own account and I briefly explore three advantages given by the acceptance of the latter.