Abstract
The Triple Helix ) of university–industry–government relations can first be considered as an institutional network. However, the correlations in the patterns of relations provide another topology: that of a vector space. Meanings are provided from positions in this latter topology and from the perspective of hindsight. Meanings can be shared, and sharing generates redundancy. Increasing redundancy provides new options and reduces uncertainty; reducing uncertainty improves the innovative climate, and the generation of options is crucial for innovation. The knowledge base provides an engine of the economy by evolving in terms of generating new options. The trade-off between the evolutionary generation of redundancy and the historical variation providing uncertainty can be measured as negative and positive information, respectively. In a number of studies of national systems of innovation, this TH synergy indicator has been used to analyze regions and sectors in which uncertainty was significantly reduced. The quality of innovation systemsinnovation system can thus be quantified at different geographical scales and in terms of sectors such as high- and medium-tech manufacturing or knowledge-intensive services ).